Affiliation: University of London
- Anomalous properties of spray dried solid dispersionsHisham Al-Obaidi
Department of Pharmaceutics, The School of Pharmacy, University of London, 29 39 Brunswick Square, London WC1N 1AX, UK
J Pharm Sci 98:4724-37. 2009..This result supports the hypothesis that the polymer conformation may significantly change the properties of the solid dispersion...
- Evaluation of griseofulvin binary and ternary solid dispersions with HPMCASHisham Al-Obaidi
The School of Pharmacy, University of London, 29 39 Brunswick Square, London, WC1N 1AX, UK
AAPS PharmSciTech 10:1172-7. 2009..These results reveal significant stability of the amorphous form due to the hydrogen bond formation with the polymer. The addition of the third polymer improved the stability but had a minor impact on dissolution...
- Investigation of preparation methods on surface/bulk structural relaxation and glass fragility of amorphous solid dispersionsPeng Ke
Department of Pharmaceutics, School of Pharmacy, University of London, 29 39 Brunswick Square, London WC1 N 1AX, UK
Int J Pharm 422:170-8. 2012..6, -4.2 and 16.7°C respectively which correlated well with their physical stability results. Therefore, T(0) appears to be a better indicator than T(g) for predicting stability of amorphous materials...
- Atypical effects of incorporated surfactants on stability and dissolution properties of amorphous polymeric dispersionsHisham Al-Obaidi
The School of Pharmacy, University of Reading, Reading, UK
J Pharm Pharmacol 68:1373-1383. 2016..To understand the impact of ionic and non-ionic surfactants on the dissolution and stability properties of amorphous polymeric dispersions using griseofulvin (GF) as a model for poorly soluble drugs...