University of Oxford

Summary

Organization: University of Oxford
Country: UK

Top Publications

  1. pmc Reticular alignment: a progressive corner-cutting method for multiple sequence alignment
    Adrienn Szabó
    Computer and Automation Research Institute, Hungarian Academy of Sciences, Lágymányosi u 11, 1111 Budapest, Hungary
    BMC Bioinformatics 11:570. 2010
  2. doi Alternative activation of macrophages: an immunologic functional perspective
    Fernando O Martinez
    Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom
    Annu Rev Immunol 27:451-83. 2009
  3. pmc The prevalence of mental disorders among the homeless in western countries: systematic review and meta-regression analysis
    Seena Fazel
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, United Kingdom
    PLoS Med 5:e225. 2008
  4. doi Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2003-2004
    David J Harvey
    Department of Biochemistry, Oxford Glycobiology Institute, University of Oxford, Oxford OX1 3QU, UK
    Mass Spectrom Rev 28:273-361. 2009
  5. doi Mathematical models of plant-soil interaction
    Tiina Roose
    OCIAM and CMB, Mathematical Institute, University of Oxford, 24 29 St Giles, Oxford OX1 3LB, UK
    Philos Trans A Math Phys Eng Sci 366:4597-611. 2008
  6. doi Photophysics and deactivation pathways of thymine
    Gunther Zechmann
    Physical and Theoretical Chemistry Laboratory, Oxford University, South Parks Road, Oxford OX1 3QZ, UK
    J Phys Chem A 112:8273-9. 2008
  7. doi Biochemistry. A natural choice for activating hydrogen
    Fraser A Armstrong
    Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3QR, UK
    Science 321:498-9. 2008
  8. ncbi Toll-like receptor 4 and CD14 polymorphisms in ankylosing spondylitis: evidence of a weak association in Finns
    Jennifer J Pointon
    NIHR OxfordMusculoskeletal Biomedical Research Unit and BotnarResearch Centre, Oxford, UK
    J Rheumatol 35:1609-12. 2008
  9. pmc Gallbladder disease and use of transdermal versus oral hormone replacement therapy in postmenopausal women: prospective cohort study
    Bette Liu
    Epidemiology Unit, University of Oxford, Oxford OX3 7LF
    BMJ 337:a386. 2008
  10. doi A pilot randomised controlled trial of a brief cognitive behavioural group intervention to reduce recurrence rates in late life depression
    Philip Wilkinson
    Department of Psychiatry, University of Oxford, Oxford, UK
    Int J Geriatr Psychiatry 24:68-75. 2009

Research Grants

  1. Gender, Relationship Dynamics, and HIV Risk
    Don Operario; Fiscal Year: 2007
  2. The international 1q type 2 diabetes consortium
    MARK IAN MCCARTHY; Fiscal Year: 2010
  3. The international 1q type 2 diabetes consortium
    Mark McCarthy; Fiscal Year: 2007
  4. INNATE IMMUNITY
    Siamon Gordon; Fiscal Year: 2005
  5. Monitoring tobacco mortality in 2M adults in 4 countries
    Richard Peto; Fiscal Year: 2004
  6. Starburst Viruses: A paradigm for modification of biological surfaces
    Leonard Seymour; Fiscal Year: 2007
  7. Neural Ensemble Codes in Drosophila Olfaction
    GERO MIESENBOECK; Fiscal Year: 2003
  8. Neural Ensemble Codes in Drosophila Olfaction
    GERO MIESENBOECK; Fiscal Year: 2007
  9. Genetically Encoded Phototriggers of Neuronal Activity
    GERO MIESENBOECK; Fiscal Year: 2006
  10. Neural Ensemble Codes in Drosophila Olfaction
    GERO MIESENBOECK; Fiscal Year: 2006

Detail Information

Publications62

  1. pmc Reticular alignment: a progressive corner-cutting method for multiple sequence alignment
    Adrienn Szabó
    Computer and Automation Research Institute, Hungarian Academy of Sciences, Lágymányosi u 11, 1111 Budapest, Hungary
    BMC Bioinformatics 11:570. 2010
    ..The program contains a threshold parameter on which the size of the network depends. The larger the threshold parameter and thus the network, the deeper the search in the alignment space for better scored alignments...
  2. doi Alternative activation of macrophages: an immunologic functional perspective
    Fernando O Martinez
    Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom
    Annu Rev Immunol 27:451-83. 2009
    ..The evidence for in vivo alternative activation of macrophages is also analyzed, with nematode infection as prototypic disease. Finally, we revisit the concept of macrophage activation in the context of the immune response...
  3. pmc The prevalence of mental disorders among the homeless in western countries: systematic review and meta-regression analysis
    Seena Fazel
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, United Kingdom
    PLoS Med 5:e225. 2008
    ..We undertook a systematic review of surveys of such disorders in homeless people...
  4. doi Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2003-2004
    David J Harvey
    Department of Biochemistry, Oxford Glycobiology Institute, University of Oxford, Oxford OX1 3QU, UK
    Mass Spectrom Rev 28:273-361. 2009
    ....
  5. doi Mathematical models of plant-soil interaction
    Tiina Roose
    OCIAM and CMB, Mathematical Institute, University of Oxford, 24 29 St Giles, Oxford OX1 3LB, UK
    Philos Trans A Math Phys Eng Sci 366:4597-611. 2008
    ..Finally, we discuss different future avenues of research and how we believe these should be approached so that in the long term it will be possible to develop a valid, quantitative whole-plant model...
  6. doi Photophysics and deactivation pathways of thymine
    Gunther Zechmann
    Physical and Theoretical Chemistry Laboratory, Oxford University, South Parks Road, Oxford OX1 3QZ, UK
    J Phys Chem A 112:8273-9. 2008
    ..Two distinct types of paths were observed, both with features that should delay the internal conversion to the ground state. This is shown to provide a possible explanation for the relatively long excited-state lifetime of thymine...
  7. doi Biochemistry. A natural choice for activating hydrogen
    Fraser A Armstrong
    Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3QR, UK
    Science 321:498-9. 2008
  8. ncbi Toll-like receptor 4 and CD14 polymorphisms in ankylosing spondylitis: evidence of a weak association in Finns
    Jennifer J Pointon
    NIHR OxfordMusculoskeletal Biomedical Research Unit and BotnarResearch Centre, Oxford, UK
    J Rheumatol 35:1609-12. 2008
    ..To investigate the association of CD14 and Toll-like receptor (TLR4) with ankylosing spondylitis (AS)...
  9. pmc Gallbladder disease and use of transdermal versus oral hormone replacement therapy in postmenopausal women: prospective cohort study
    Bette Liu
    Epidemiology Unit, University of Oxford, Oxford OX3 7LF
    BMJ 337:a386. 2008
    ..To determine whether transdermal compared with oral use of hormone replacement therapy reduces the risk of gallbladder disease in postmenopausal women...
  10. doi A pilot randomised controlled trial of a brief cognitive behavioural group intervention to reduce recurrence rates in late life depression
    Philip Wilkinson
    Department of Psychiatry, University of Oxford, Oxford, UK
    Int J Geriatr Psychiatry 24:68-75. 2009
    ..To apply the intervention in a research setting and to estimate its effect on recurrence rates in recently depressed older adults, in preparation for a definitive study...
  11. doi Autoimmunizing mechanisms in thymoma and thymus
    Nick Willcox
    Neuroscience Group, Weatherall Institute for Molecular Medicine, University of Oxford, England, UK
    Ann N Y Acad Sci 1132:163-73. 2008
    ..Together, moreover, our findings implicate both myoid cells and TEC in autoimmunization, and thus strongly support our hypothesis...
  12. ncbi In vitro assays for assessing the potential for copper complexes to function as radiopharmaceutical agents
    P J Barnard
    Siemens Oxford Molecular Imaging Laboratory, Inorganic Chemistry Laboratory, University of Oxford, Oxford, UK
    Q J Nucl Med Mol Imaging 52:235-44. 2008
    ..Evaluation of complex stability and speciation over a range of pH values may also be used to obtain information on potential biodistribution...
  13. pmc Opa protein repertoires of disease-causing and carried meningococci
    Martin J Callaghan
    Dept of Paediatrics, Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Churchill Hospital, Headington, Oxford OX3 9DU, United Kingdom
    J Clin Microbiol 46:3033-41. 2008
    ..Meningococcal Opa repertoire is strongly linked to MLST genotype irrespective of epidemiological sampling and therefore correlates with invasiveness. It is not, however, strongly associated with severity of meningococcal disease...
  14. pmc Patterns of coronary heart disease mortality over the 20th century in England and Wales: Possible plateaus in the rate of decline
    Steven Allender
    Division of Public Health and Primary Health Care, University of Oxford, Oxford, UK
    BMC Public Health 8:148. 2008
    ..Recent work suggests that the rate of change in some groups has begun to decrease and may be starting to plateau or even reverse...
  15. pmc Genetic association study for RSV bronchiolitis in infancy at the 5q31 cytokine cluster
    J T Forton
    The Wellcome Trust Centre for Human Genetics, University of Oxford, UK
    Thorax 64:345-52. 2009
    ..A recent twin study estimated a heritable contribution of 22% to RSV bronchiolitis. Genetic epidemiology provides a new approach to identifying important immune determinants of disease severity...
  16. ncbi Assessment of platelet function in the laboratory
    P Harrison
    Oxford Haemophilia and Thrombosis Centre, Churchill Hospital, Oxford, OX3 7LJ, UK
    Hamostaseologie 29:25-31. 2009
    ....
  17. doi Meta-analysis of neuroimaging data: a comparison of image-based and coordinate-based pooling of studies
    Gholamreza Salimi-Khorshidi
    Centre for Functional MRI of the Brain FMRIB, University of Oxford, Oxford, UK
    Neuroimage 45:810-23. 2009
    ..To make IBMA analyses practical, however, the neuroimaging field needs to develop an effective mechanism for sharing image data, including whole-brain images of both effect estimates and their standard errors...
  18. doi Species differences in executive function correlate with hippocampus volume and neocortex ratio across nonhuman primates
    Susanne Shultz
    British Academy Centenary Research Project, Institute of Cognitive and Evolutionary Anthropology, University of Oxford, 64 Banbury Rd, Oxford OX2 6PN, England
    J Comp Psychol 124:252-60. 2010
    ..They also suggest that commonly used indices of encephalization, such as residuals of brain volume regressed on body size, may confound rather than clarify matters...
  19. pmc Estimating the number of paediatric fevers associated with malaria infection presenting to Africa's public health sector in 2007
    Peter W Gething
    Spatial Ecology and Epidemiology Group, Department of Zoology, University of Oxford, Oxford, United Kingdom
    PLoS Med 7:e1000301. 2010
    ..Here we compute the number of fevers likely to present to public health facilities in Africa and the estimated number of these fevers likely to be infected with Plasmodium falciparum malaria parasites...
  20. doi Systematic review of the prevalence of suicide in veterinary surgeons
    B Platt
    Centre for Suicide Research, Department of Psychiatry, University of Oxford, Oxford OX3 7JX, UK
    Occup Med (Lond) 60:436-46. 2010
    ..There is preliminary evidence to suggest that veterinary surgeons are a group at risk...
  21. pmc Can we rely on the best trial? A comparison of individual trials and systematic reviews
    Paul P Glasziou
    Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, UK
    BMC Med Res Methodol 10:23. 2010
    ..However, for many clinical questions a systematic review will not be available, or may not be up to date. One option could be to use the evidence from an individual trial to answer the question?..
  22. pmc An expedient route to substituted furans via olefin cross-metathesis
    Timothy J Donohoe
    Department of Chemistry, University of Oxford, Oxford, OX1 3TA UK
    Proc Natl Acad Sci U S A 107:3373-6. 2010
    ..These cascade processes portend further opportunities for the regiocontrolled preparation of other highly substituted aromatic and heteroaromatic classes...
  23. doi Genetic influences in the aetiology of femoroacetabular impingement: a sibling study
    T C B Pollard
    Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences University of Oxford, Headington, Oxford OX3 7LD, UK
    J Bone Joint Surg Br 92:209-16. 2010
    ..This risk appears to be manifested through not only abnormal joint morphology, but also through other factors which may modulate progression of the disease...
  24. pmc Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination
    Simon Myers
    Department of Statistics, Oxford University, 1 South Parks Road, Oxford OX1 3TG, UK
    Science 327:876-9. 2010
    ..The involvement of PRDM9, which causes histone H3 lysine 4 trimethylation, implies that there is a common mechanism for recombination hotspots in eukaryotes but raises questions about what forces have driven such rapid change...
  25. doi The genetics of mood disorders
    Jennifer Y F Lau
    Department of Experimental Psychology, University of Oxford, 0X1 4AU, United Kingdom
    Annu Rev Clin Psychol 6:313-37. 2010
    ....
  26. doi Cohesin: its roles and mechanisms
    Kim Nasmyth
    Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom
    Annu Rev Genet 43:525-58. 2009
    ..Recent evidence suggests that cohesin acts as a novel topological device that traps chromosomal DNA within a large tripartite ring formed by its core subunits...
  27. doi Detection of MCI in the clinic: evaluation of the sensitivity and specificity of a computerised test battery, the Hopkins Verbal Learning Test and the MMSE
    Celeste A de Jager
    Oxford Project to Investigate Memory and Ageing OPTIMA, Department of Physiology, Anatomy and Genetics, University of Oxford, UK
    Age Ageing 38:455-60. 2009
    ..We evaluated whether the computerised cognitive test battery, CogState, was as sensitive to MCI as two well-validated 'paper-and-pencil' tests, the Hopkins Verbal Learning Test (HVLT) and the Mini-Mental Status Examination (MMSE)...
  28. ncbi Megaphylogeny, cell body plans, adaptive zones: causes and timing of eukaryote basal radiations
    Thomas Cavalier-Smith
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom
    J Eukaryot Microbiol 56:26-33. 2009
    ..New subphyla are established for Choanozoa and Loukozoa; Amoebozoa are divided into three revised subphyla, with Variosea transferred into Conosa...
  29. doi Cytochrome c oxidase levels in chondrocytes during monolayer expansion and after return to three dimensional culture
    O A Boubriak
    Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK
    Osteoarthritis Cartilage 17:1084-92. 2009
    ....
  30. doi The importance of radiation chemistry to radiation and free radical biology (The 2008 Silvanus Thompson Memorial Lecture)
    P Wardman
    University of Oxford, Gray Cancer Institute, Mount Vernon Hospital, Northwood, Middlesex, UK
    Br J Radiol 82:89-104. 2009
    ....
  31. doi Light affects mitochondria to cause apoptosis to cultured cells: possible relevance to ganglion cell death in certain optic neuropathies
    Neville N Osborne
    Nuffield Laboratory of Ophthalmology, University of Oxford, Oxford, UK
    J Neurochem 105:2013-28. 2008
    ....
  32. doi Surprises
    L Weiskrantz
    Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, United Kingdom
    Neuropsychologia 46:771-3. 2008
  33. ncbi A computational analysis of the impact of the transient genetic imbalance on compartmentalized gene expression during sporulation in Bacillus subtilis
    Dagmar Iber
    Mathematical Institute, Centre for Mathematical Biology, University of Oxford, Oxford, UK
    J Mol Biol 360:15-20. 2006
    ..We conclude that the volume difference between the two compartments is the main determinant of cell fate...
  34. ncbi Controlled delivery of membrane proteins to artificial lipid bilayers by nystatin-ergosterol modulated vesicle fusion
    M R R de Planque
    University of Oxford, Bionanotechnology IRC, Clarendon Laboratory, Department of Physics, Oxford, UK
    IEE Proc Nanobiotechnol 153:21-30. 2006
    ....
  35. ncbi Dynamic nucleosomes and gene transcription
    Jane Mellor
    Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK
    Trends Genet 22:320-9. 2006
    ..Here, new concepts such as dynamic nucleosomes and a dynamic histone code in gene transcription are explored...
  36. ncbi Nanohazards: knowledge is our first defence
    Amanda S Barnard
    Department of Materials, University of Oxford, Parks Road, Oxford, OX1 3PH, UK
    Nat Mater 5:245-8. 2006
  37. pmc Age-dependent diet choice in an avian top predator
    Christian Rutz
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Proc Biol Sci 273:579-86. 2006
    ..Furthermore, our study is, to our knowledge, the first demonstration that prey choice of breeders, which might reflect individual hunting skills, is age-dependent in a raptor...
  38. ncbi Suicide trends in discharged patients with mood disorders: associations with selective serotonin uptake inhibitors and comorbid substance misuse
    Seena Fazel
    Department of Psychiatry, University of Oxford, Warneford Hospital, UK
    Int Clin Psychopharmacol 21:111-5. 2006
    ..We conclude that there is no evidence from this study of an increase in suicide rates following the introduction of SSRIs in the general population or in a high-risk inpatient sample...
  39. ncbi A theoretical analysis of the selection of differentially expressed genes
    Sach Mukherjee
    Department of Engineering Science, University of Oxford, Oxford OX1 3PJ, United Kingdom
    J Bioinform Comput Biol 3:627-43. 2005
    ..The utility of our approach is illustrated by comparing three widely-used gene selection methods...
  40. ncbi The dynamics of chromatin remodeling at promoters
    Jane Mellor
    Division of Molecular Genetics, Department of Biochemistry, University of Oxford, UK
    Mol Cell 19:147-57. 2005
    ..Recent advances have allowed nucleosome dynamics on promoters to be studied in real time, dramatically changing how we think about gene regulation on chromatin templates...
  41. ncbi Structural studies of glucose-6-phosphate and NADP+ binding to human glucose-6-phosphate dehydrogenase
    Masayo Kotaka
    Laboratory of Molecular Biophysics, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, England
    Acta Crystallogr D Biol Crystallogr 61:495-504. 2005
    ..The implications of possible interaction between the structural NADP(+) and G6P are considered...
  42. ncbi Parametric modelling of cost data: some simulation evidence
    Andrew Briggs
    Department of Public Health, Health Economics Research Center, University of Oxford, UK
    Health Econ 14:421-8. 2005
    ..In practical situations, where the true distribution is unknown, the sample mean generally remains the estimator of choice, especially when limited sample size prohibits detailed modelling of the cost data distribution...
  43. ncbi Barking up the wrong tree? Lexical ambiguity resolution in children with language impairments and autistic spectrum disorders
    Courtenay Frazier Norbury
    Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, UK
    J Exp Child Psychol 90:142-71. 2005
    ..These findings challenge the assumptions of weak central coherence theory and demonstrate the need for stringent language controls in the study of autistic cognition...
  44. ncbi yBlast, a graphical front end for the standalone BLAST suite
    Nicolas Buisine
    Biochemistry Department, Oxford University, Oxford, UK
    Biotechniques 37:987-9. 2004
  45. ncbi Pathogen recognition or homeostasis? APC receptor functions in innate immunity
    Siamon Gordon
    Sir William Dunn School of Pathology, South Parks Road, Oxford OXI 3RE, UK
    C R Biol 327:603-7. 2004
    ..This article will evaluate one of the paradigms that underlie innate immunity...
  46. pmc Late sodium current in the pathophysiology of cardiovascular disease: consequences of sodium-calcium overload
    D Noble
    University Laboratory of Physiology, Parks Road, Oxford OX1 3PT, UK
    Heart 92:iv1-iv5. 2006
    ..Reduction of late sodium current would therefore be expected to have therapeutic benefits, particularly in disease states such as ischaemia in which sodium-calcium overload is a major feature...
  47. ncbi The beta-adrenergic receptor antagonist metipranolol blunts zinc-induced photoreceptor and RPE apoptosis
    Neville N Osborne
    Nuffield Laboratory of Ophthalmology, University of Oxford, Oxford, United Kingdom
    Invest Ophthalmol Vis Sci 47:3178-86. 2006
    ..Furthermore, the effects of metipranolol, known to prevent retinal damage, and of other antiglaucoma drugs were determined on zinc-injured retinal cells...
  48. ncbi Functional analysis of six Kir6.2 (KCNJ11) mutations causing neonatal diabetes
    Christophe A J Girard
    University Laboratory of Physiology, Oxford University, Oxford, OX1 3PT, UK
    Pflugers Arch 453:323-32. 2006
    ..None of the mutations substantially affected the sensitivity of the channel to inhibition by the sulphonylurea tolbutamide, suggesting patients carrying these mutations may respond to these drugs...
  49. doi Facts, fantasies and fun in epithelial physiology
    C A R Boyd
    Department of Physiology, Anatomy and Genetics, University of Oxford, Le Gros Clark Building, South Parks Road, Oxford, UK
    Exp Physiol 93:303-14. 2008
    ..One example is the finding that certain amino-acid transporters may act as 'transceptors' and play a role as sensors of the extracellular environment that then regulate intracellular pathways controlling cell growth...
  50. ncbi Cerebral blood flow and ventilatory sensitivity to CO2 measured with the modified rebreathing method
    Jaideep J Pandit
    University of Oxford, Nuffield Department of Anaesthetics, John Radcliffe Hospital, UK
    Adv Exp Med Biol 605:480-5. 2008
    ....
  51. ncbi Psychopathology in adolescent and young adult criminal offenders (15-21 years) in Sweden
    Mina Fazel
    University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK
    Soc Psychiatry Psychiatr Epidemiol 43:319-24. 2008
    ....
  52. pmc Structural and functional abnormalities of the motor system in developmental stuttering
    Kate E Watkins
    Department of Experimental Psychology, University of Oxford, Oxford, UK
    Brain 131:50-9. 2008
    ....
  53. ncbi Differential effects of erythropoietin on neural and cognitive measures of executive function 3 and 7 days post-administration
    Kamilla Miskowiak
    Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, OX1 3UD, UK
    Exp Brain Res 184:313-21. 2008
    ..The present study supports the notion that Epo may have clinical applications in the treatment of psychiatric disorder characterized by cognitive dysfunction...
  54. ncbi Multiple cascade effects of oxidative stress on astroglia
    Cherie E Bond
    Department of Pharmacology, University of Oxford, Oxford OX1 3QT, United Kingdom
    Glia 55:1348-61. 2007
    ....
  55. ncbi Views of doctors in training on the importance and availability of career advice in UK medicine
    Trevor W Lambert
    Unit of Health Care Epidemiology, Department of Public Health, University of Oxford, Oxford, UK
    Med Educ 41:460-6. 2007
    ....
  56. ncbi IkappaB genetic polymorphisms and invasive pneumococcal disease
    Stephen J Chapman
    The Wellcome Trust Centre for Human Genetics, University of Oxford, and Oxford Centre for Respiratory Medicine, Churchill Hospital Site, Oxford Radcliffe Hospital, Roosevelt Drive, Oxford, OX3 7BN, UK
    Am J Respir Crit Care Med 176:181-7. 2007
    ..Rare NFKBIA mutations cause immunodeficiency with severe bacterial infection, raising the possibility that common IkappaB gene polymorphisms confer susceptibility to common bacterial disease...
  57. ncbi Investigational treatment for vascular cognitive impairment
    Jacqueline Birks
    University of Oxford, Cochrane Dementia and Cognitive Improvement Group, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Expert Opin Investig Drugs 16:647-58. 2007
    ..For the purposes of this review, the authors focus on interventions that have been evaluated by randomised controlled trials...
  58. ncbi Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells
    Helen R Dawe
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK
    J Cell Sci 120:7-15. 2007
    ....
  59. ncbi Immunoregulation in normal pregnancy and pre-eclampsia: an overview
    Ian L Sargent
    Nuffield Department of Obstetrics and Gynaecology, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    Reprod Biomed Online 13:680-6. 2006
    ..There is evidence that such trophoblast debris interacts with maternal leukocytes and endothelial cells to stimulate the release of proinflammatory cytokines, which could then trigger the maternal disease...
  60. ncbi Strategies for managing antidepressant-induced sexual dysfunction: a review
    Matthew J Taylor
    University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, United Kingdom
    Curr Psychiatry Rep 8:431-6. 2006
    ..Many specific antidotes have been trialed but with lack of convincing benefit in most cases. However, where antidepressants cause erectile dysfunction, the use of sildenafil has the largest and most consistent evidence base...
  61. ncbi Total synthesis of (+)-cis-sylvaticin: double oxidative cyclization reactions catalyzed by osmium
    Timothy J Donohoe
    Department of Chemistry, University of Oxford, Chemistry Research Laboratory, UK
    J Am Chem Soc 128:13704-5. 2006
    ..The natural product was then prepared by a short sequence of reactions that is exceptionally concise: the final route being just 13 linear steps and 19 chemical operations in total...
  62. ncbi Meta-analysis of genetic association studies
    Marcus R Munafo
    Cancer Research UK GPRG, Department of Clinical Pharmacology, Radcliffe Infirmary, University of Oxford, Oxford OX2 6HE, UK
    Trends Genet 20:439-44. 2004
    ..If heterogeneity is adequately recognized and taken into account, meta-analysis can confirm the involvement of a genetic variant, but it is not a substitute for an adequately powered primary study...

Research Grants22

  1. Gender, Relationship Dynamics, and HIV Risk
    Don Operario; Fiscal Year: 2007
    ..Findings will contribute toward developing a theory-driven, culturally appropriate relationship-focused HIV prevention intervention with these groups. ..
  2. The international 1q type 2 diabetes consortium
    MARK IAN MCCARTHY; Fiscal Year: 2010
    ..This information will contribute to future diagnostic and therapeutic advances in the clinical management of this condition. ..
  3. The international 1q type 2 diabetes consortium
    Mark McCarthy; Fiscal Year: 2007
    ..This information will contribute to future diagnostic and therapeutic advances in the clinical management of this condition. ..
  4. INNATE IMMUNITY
    Siamon Gordon; Fiscal Year: 2005
    ..The meeting will conclude with examples of how disorders of innate immunity can give rise to important diseases. ..
  5. Monitoring tobacco mortality in 2M adults in 4 countries
    Richard Peto; Fiscal Year: 2004
    ..We already have evidence that this has taken place in China, where the earliest study was established. ..
  6. Starburst Viruses: A paradigm for modification of biological surfaces
    Leonard Seymour; Fiscal Year: 2007
    ..g. hepatitis) and inherited diseases (e.g. cystic fibrosis) and notably in development of antibody-resistant viral vaccines suitable for repeated use in diseases such as HIV, malaria, TB and influenza. ..
  7. Neural Ensemble Codes in Drosophila Olfaction
    GERO MIESENBOECK; Fiscal Year: 2003
    ..abstract_text> ..
  8. Neural Ensemble Codes in Drosophila Olfaction
    GERO MIESENBOECK; Fiscal Year: 2007
    ..abstract_text> ..
  9. Genetically Encoded Phototriggers of Neuronal Activity
    GERO MIESENBOECK; Fiscal Year: 2006
    ..abstract_text> ..
  10. Neural Ensemble Codes in Drosophila Olfaction
    GERO MIESENBOECK; Fiscal Year: 2006
    ..abstract_text> ..