Genomes and Genes
University of London
Organization: University of London
- Development of motion processing in children with autismDagmara Annaz
Department of Developmental Sciences, Division of Psychology and Language Science, University College London, UK
Dev Sci 13:826-38. 2010..Finally, Gabor display thresholds appeared to develop typically in children with autism...
- Psychiatric institutions, their architecture, and the politics of regional autonomy in the Austro-Hungarian monarchyLeslie Topp
Lecturer in History of Art and Architecture, Birkbeck College, Faculty of Continuing Education, 26 Russell Square, London WC1B 5DQ, UK
Stud Hist Philos Biol Biomed Sci 38:733-55. 2007..The spatial arrangement and visual articulation of the two asylums is interpreted in the context of the interaction of psychiatry and the politics of regional autonomy...
- Distinct processing of objects and faces in the infant brainVictoria Southgate
Birkbeck, University of London, London, UK
J Cogn Neurosci 20:741-9. 2008..These data suggest markedly different processing of objects and faces in the infant brain and, furthermore, indicate that the representation underpinned by the posterior gamma increase may contain only spatiotemporal information...
- Bilingualism and memory: early 19th century ideas about the significance of polyglot aphasiaMarjorie Lorch
School of Languages, Linguistics and Culture, Birkbeck College, University of London, London, UK
Cortex 43:658-66. 2007..Consideration of these writings helps to illuminate the history of ideas about the organization of language in the brain...
- Processing acoustic change and novelty in newborn infantsElena Kushnerenko
Centre for Brain and Cognitive Development, School of Psychology, Birkbeck College, Henry Wellcome Building, London Malet Street, WC1E 7HX, UK
Eur J Neurosci 26:265-74. 2007..Results are discussed in terms of developmental refinement of the initially broadly tuned neonate auditory system...
- Variation in community intervention programmes and consequences for children and families: the example of Sure Start Local ProgrammesEdward Melhuish
Institute for the Study of Children Families and Social Issues, Birkbeck, University of London, UK
J Child Psychol Psychiatry 48:543-51. 2007..A national evaluation examined the links between variation in programme implementation and effectiveness...
- Pandemic in print: the spread of influenza in the Fin de SiècleJames Mussell
Faculty of Continuing Education, Birkbeck College, London WC1B 5DQ, United Kingdom
Endeavour 31:12-7. 2007..This link between the press and the illness made the epidemic seem a curious symptom of the modern communications technologies that increasingly defined the age...
- Benchmarking natural-language parsers for biological applications using dependency graphsAndrew B Clegg
School of Crystallography, Birkbeck, University of London, Malet Street, London WC1E 7HX, UK
BMC Bioinformatics 8:24. 2007..We also demonstrate how this method can be easily tailored to various application-driven criteria...
- Teachers in the wildGergely Csibra
School of Psychology, Birkbeck, University of London, Malet Street, London WC1E 7HX, UK
Trends Cogn Sci 11:95-6. 2007..However, these behaviours, although capable of facilitating information or skill acquisition in youngsters, could not support the transmission of cultural knowledge across individuals, which human teaching arguably serves...
- Atypical epigenesisAnnette Karmiloff-Smith
Developmental Neurocognition Lab, Birkbeck, University of London, London, UK
Dev Sci 10:84-8. 2007..Atypical epigenesis may often involve a lack of specialization and localization of brain function over developmental time, even in cases of behavioural proficiency...
- Factors influencing newborns' preference for faces with eye contactTeresa Farroni
Dipartimento di Psicologia dello Sviluppo e della Socializzazione, University of Padua, Via Venezia 8, 35131 Padua, Italy
J Exp Child Psychol 95:298-308. 2006..Overall, these results further the view that relatively simple perceptual biases in newborns may be an essential foundation for later social-cognitive development...
- Lucky 13-microtubule depolymerisation by kinesin-13 motorsCarolyn A Moores
School of Crystallography, Birkbeck College, Malet Street, London, WC1E 7HX, UK
J Cell Sci 119:3905-13. 2006..Such carefully controlled localisation and regulation makes these kinesins efficient, multi-tasking molecular motors...
- Distinct roles of doublecortin modulating the microtubule cytoskeletonCarolyn A Moores
School of Crystallography, Birkbeck College, University of London, London, UK
EMBO J 25:4448-57. 2006..These distinct properties combine to give doublecortin a unique function in microtubule regulation, a role that cannot be compensated for by other microtubule-stabilising proteins and nucleating factors...
- SiPep: a system for the prediction of tissue-specific minor histocompatibility antigensM Halling-Brown
Institute of Structural Molecular Biology, School of Crystallography, Birkbeck College, University of London, Malet Street, London, WC1E 7HX, UK
Int J Immunogenet 33:289-95. 2006..The SiPep tools and SNPBinder database are available free of charge via the internet. An HTML interface providing search facilities can be found at the following address: http://www.sipep.org/...
- Strand bias structure in mouse DNA gives a glimpse of how chromatin structure affects gene expressionKenneth J Evans
School of Crystallography, Birkbeck College, University of London, Malet Street, London, WC1E 7HX, UK
BMC Genomics 9:16. 2008..On a single strand of genomic DNA the number of As is usually about equal to the number of Ts (and similarly for Gs and Cs), but deviations have been noted for transcribed regions and origins of replication...
- Ten-month-olds' selective use of visual dimensions in category learningTeodora Gliga
Centre for Brain and Cognitive Development, School of Psychology, Birkbeck, University of London, Malet Street, London WC1E 7HX, UK
Infant Behav Dev 31:287-93. 2008..These results are discussed with reference to the development of selective feature processing in infancy...
- Protein structure fitting and refinement guided by cryo-EM densityMaya Topf
School of Crystallography, Birkbeck College, University of London, Malet Street, London WC1E 7HX, United Kingdom
Structure 16:295-307. 2008..At approximately 10 A resolution, Calpha rmsd between the initial and final structures was reduced on average by approximately 53%. The method is automated and can refine both experimental and predicted atomic structures...
- Infant attachment security and the timing of puberty: testing an evolutionary hypothesisJay Belsky
Institute for the Study of Children, Families and Social Issues, Birkbeck University of London, London, United Kingdom
Psychol Sci 21:1195-201. 2010..These results support a conditional-adaptational view of individual differences in attachment security and raise questions about the biological mechanisms responsible for the attachment effects we discerned...
- A computational analysis of the antigenic properties of haemagglutinin in influenza A H3N2William D Lees
Department of Biological Sciences and Institute of Structural and Molecular Biology, Birkbeck College, University of London, Malet Street, London WC1E 7HX, UK
Bioinformatics 26:1403-8. 2010..The virus is known to exhibit sudden jumps in antigenic distance, and prediction of such novel strains from amino acid sequence differences remains a challenge...
- Using non-homogeneous models of nucleotide substitution to identify host shift events: application to the origin of the 1918 'Spanish' influenza pandemic virusMario dos Reis
The MRC National Institute for Medical Research, London, NW7 1AA, UK
J Mol Evol 69:333-45. 2009..This would suggest that the virus was introduced into humans sometime between 1913 and 1918...
- Nativism versus neuroconstructivism: rethinking the study of developmental disordersAnnette Karmiloff-Smith
Birkbeck College, University of London, UK
Dev Psychol 45:56-63. 2009..e., the emergent property over developmental time of dynamic, multidirectional interactions between genes, brain, cognition, behavior, and environment) with domain-specific outcomes impossible without the process of development...
- Spatial structure affects temporal judgments: evidence for a synchrony binding codeSamuel Cheadle
School of Psychology, Birkbeck, University of London, UK
J Vis 8:12.1-12. 2008....
- Towards a lightweight generic computational grid framework for biological researchMark D Halling-Brown
Institute of Structural and Molecular Biology, School of Crystallography, Birkbeck College, Malet Street, London, WC1E 7HX, UK
BMC Bioinformatics 9:407. 2008..This is particularly true in the biological field, whether to facilitate the analysis of large high-throughput data sets, or to perform large numbers of complex simulations - a characteristic of the emerging field of systems biology...
- A pulse--radiolysis approach to fast reductive cleavage of a disulfide bond to uncage enzyme activityLilia Milanesi
Centre for Chemical Biology, Department of Chemistry, Krebs Institute for Biomolecular Science, University of Sheffield, Sheffield S3 7HF, UK
Free Radic Biol Med 45:1271-8. 2008....
- Analogy as relational priming: a developmental and computational perspective on the origins of a complex cognitive skillRobert Leech
School of Psychology, Birkbeck, University of London, London, WC1E 7HX, United Kingdom
Behav Brain Sci 31:357-78; discussion 378-414. 2008....
- Changes in induced hues at low luminance and following dark adaptation suggest rod-cone interactions may differ for luminance increments and decrementsA J Shepherd
School of Psychology, Birkbeck College, University of London, United Kingdom
Vis Neurosci 25:387-94. 2008....
- Part one: introduction to Quentin Skinner: interpretation in psychoanalysis and historyDaniel Pick
Birkbeck, University of London, Maret Street, London WCIE 7HX
Int J Psychoanal 89:637-45. 2008
- Donor substrate recognition in the raffinose-bound E342A mutant of fructosyltransferase Bacillus subtilis levansucraseGuoyu Meng
School of Biosciences, University of Birmingham, Birmingham, B15 2TT, UK
BMC Struct Biol 8:16. 2008..Still, the structural determinants of the fructosyl transfer reaction thus far have been only partially defined...
- Face transplantation and living a flourishing lifeA C Grayling
Lancet 371:707-8. 2008
- Visualisation of a kinesin-13 motor on microtubule end mimicsCarolyn A Moores
School of Crystallography, Birkbeck College, Malet Street, London WC1E 7HX, UK
J Mol Biol 377:647-54. 2008..This enabled us to detect conformational changes that the motor undergoes during depolymerisation. Our data suggest that such tubulin oligomers can be used to examine other microtubule end-binding proteins...
- Asymmetric bagging and random subspace for support vector machines-based relevance feedback in image retrievalDacheng Tao
School of Computer Science and Information Systems, Birkbeck, University of London, Malet Street, London WC1E 7HX, UK
IEEE Trans Pattern Anal Mach Intell 28:1088-99. 2006..Finally, by integrating AB-SVM and RS-SVM, an asymmetric bagging and random subspace SVM (ABRS-SVM) is built to solve these three problems and further improve the relevance feedback performance...
- Recognition memory and awareness: A high-frequency advantage in the accuracy of knowingVernon H Gregg
School of Psychology, Birkbeck College, University of London, UK
Memory 14:265-75. 2006..The results are discussed in relation to theories of knowing, particularly those incorporating perceptual and conceptual fluency...
- Child-rearing antecedents of intergenerational relations in young adulthood: a prospective studyJ Belsky
School of Psychology, Birkbeck College, University of London, England
Dev Psychol 37:801-13. 2001....
- Emanuel Miller lecture developmental risks (still) associated with early child careJ Belsky
Institute for the Study of Children, Families and Social Issues, Birkbeck College, University of London, UK
J Child Psychol Psychiatry 42:845-59. 2001....
- Increased visual after-effects following pattern adaptation in migraine: a lack of intracortical excitation?A J Shepherd
School of Psychology, Birkbeck College, London, UK
Brain 124:2310-8. 2001..There were no differences between migraine subgroups classified according to the presence or absence of aura. These results are discussed in terms of models of cortical function in migraine...
- Determinants of coping: some alternative explanations and measurement issuesP Dewe
Department of Organizational Psychology, Birkbeck College, University of London, Malet Street, London WC 1E 7HX, England
Psychol Rep 88:832-4. 2001....
- Changing patterns of teenage pregnancy: population based study of small areasA McLeod
MRC Social and Public Health Sciences Unit, University of Glasgow, Glasgow G12 8RZ
BMJ 323:199-203. 2001..To measure the impact of socioeconomic deprivation on rates of teenage pregnancy and the extent of local variation in pregnancy rates in Scotland, and to examine how both have changed over time...
- Phonological and orthographic approaches to the treatment of word retrieval in aphasiaR Herbert
School of Psychology, Birkbeck, University of London, Malet Street, London, WC1E 7HX
Int J Lang Commun Disord 36:7-12. 2001..The results from both phases were encouraging with improved word retrieval for three out of the four participants. The implications for clinical practice are discussed...
- 'We don't sing the chorus when the folksinger's here': the learning society and health careT Schuller
Faculty of Continuing Education, Birkbeck College, 26 Russell Square, London WC1B 5DQ, UK
Nurse Educ Today 20:227-32. 2000..It deals with three key issues: initial education and the implications for continuing education and training; markets, investment and the returns to CET; and cultural factors. The paper concludes with some key implications...
- An ERP study of sustained spatial attention to stimulus eccentricityM Eimer
Department of Psychology, Birkbeck College, University of London, Malet Street, London, UK
Biol Psychol 52:205-20. 2000..However, ERPs also suggested the presence of selective mechanisms that exclude irrelevant stimuli located between two simultaneously attended areas...
- Identification of arsenosugars at the picogram level using nanoelectrospray quadrupole time-of-flight mass spectrometryS A Pergantis
School of Biological and Chemical Sciences, Birkbeck College, University of London, U K
Anal Chem 72:357-66. 2000....
- The 2.0 A structure of the second calponin homology domain from the actin-binding region of the dystrophin homologue utrophinN H Keep
MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
J Mol Biol 285:1257-64. 1999..Here, we present the 2.0 A structure of the second calponin homology domain of utrophin solved by X-ray crystallography, and compare it to the other calponin homology domains previously determined from spectrin and fimbrin...
- A novel method for structure-based prediction of ion channel conductance propertiesO S Smart
Department of Crystallography, Birkbeck College, University of London, England www http www cryst bbk ac uk ubcg8ab smart html
Biophys J 72:1109-26. 1997..Results for a cholera toxin B-subunit crystal structure agree well with the measured values. The difficulty in interpreting such studies is discussed, with the conclusion that measurements on channels of known structure are required...
- Attentional tracking and inhibition of return in dynamic displaysH J Muller
Department of Psychology, University of London, England
Percept Psychophys 58:224-49. 1996..The implications of the present findings for the role of attentive tracking and IOR in dynamic scenes are discussed...
- Comparative biochemical effects of low doses of mercury II chloride in the F344 rat and the multimammate mouse (Mastomys natalensis)E Holmes
Department of Chemistry, Birkbeck College, London, UK
Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 114:7-15. 1996..Since gamma GT activity is involved in the tubular reabsorption of Hg2+, the lower levels of gamma GT in Mastomys might partially account for the lower toxicity of Hg2+ in this species...
- The X-ray crystal structure of human gamma S-crystallin C-terminal domainAndrew G Purkiss
School of Crystallography, Birkbeck College, Malet Street, London WC1E 7HX, United Kingdom
J Biol Chem 277:4199-205. 2002..Two glutamines found in lattice contacts may be important for short range interactions in the lens. An asparagine known to be deamidated in human cataract is located in a highly ordered structural region...
- Increased visual after-effects in migraine following pattern adaptation extend to simultaneous tilt illusionA J Shepherd
School of Psychology, Birkbeck College, University of London, Malet Street, London WC1E 7HX, UK
Spat Vis 16:33-43. 2002..The results are discussed in terms of alternative models of cortical function, including a lack of excitation and reduced central energy reserves...
- Analyses of circular dichroism spectra of membrane proteinsB A Wallace
Department of Crystallography, Birkbeck College, University of London, London WC1E 7HX, UK
Protein Sci 12:875-84. 2003..These results have important consequences for studies that seek to use the existing soluble protein reference databases for the analyses of membrane proteins...
- Subcortical face processingMark H Johnson
Centre for Brain and Cognitive Development, Birkbeck University of London, 32 Torrington Square, London WC1E 7JL, UK
Nat Rev Neurosci 6:766-74. 2005....
- Educating executive attentionKarla Holmboe
Centre for Brain and Cognitive Development, Birkbeck College, University of London, 32 Torrington Square, London WC1E 7JL, United Kingdom
Proc Natl Acad Sci U S A 102:14479-80. 2005
- Cutaneous saltation within and across arms: a new measure of the saltation illusion in somatosensationMartin Eimer
Department of Psychology, Birkbeck College, University of London, England
Percept Psychophys 67:458-68. 2005..These results challenge the view that saltation is a purely attentional phenomenon, but they are inconsistent with the idea that this illusion is produced in the primary somatosensory cortex...
- Loss aversion and inhibition in dynamical models of multialternative choiceMarius Usher
Department of Psychology, Birkbeck College, University of London, London, England
Psychol Rev 111:757-69. 2004..Usher & J. L. McClelland, 2001) that relies on inhibition independent of similarity among alternatives. The model accounts for the 3 effects and makes testable predictions contrasting with those of the Roe et al. (2001) model...
- New rapamycin derivatives by precursor-directed biosynthesisPhilip A S Lowden
School of Chemistry, University of Exeter, Stocker Road, Exeter, EX4 4QD, UK
Chembiochem 5:535-8. 2004
- Thinking, recognition, and othernessStephen Frosh
School of Psychology, Birkbeck College, Malet Street, London WC1E 7HX, United Kingdom
Psychoanal Rev 90:771-89. 2003
- Anterior and posterior attentional control systems use different spatial reference frames: ERP evidence from covert tactile-spatial orientingMartin Eimer
Department of Psychology, Birkbeck College, University of London, London, UK
Psychophysiology 40:924-33. 2003..It is suggested that a posterior process operates on the basis of external spatial coordinates, whereas an anterior process is based primarily on anatomically defined spatial codes...
- Response facilitation and inhibition in subliminal primingMartin Eimer
School of Psychology, Birkbeck College, University of London, Malet Street, London WC1E 7HX, UK
Biol Psychol 64:7-26. 2003..Overall, results demonstrate that inhibitory mechanisms are involved in the control of response processes, even when motor activations are triggered by stimuli that are not accessible to conscious awareness...
- Are developmental disorders like cases of adult brain damage? Implications from connectionist modellingMichael Thomas
Neurocognitive Development Unit, Institute of Child Health and School of Psychology, Birkbeck College, University of London, London WC1E 7HX, United Kingdom
Behav Brain Sci 25:727-50; discussion 750-87. 2002....
- Revealing the set of mutually correlated positions for the protein families of immunoglobulin foldBoris Galitsky
Knowledge Trail Inc, Natick, MA 01760, USA
In Silico Biol 3:241-64. 2003..Hence, the set of constant positions (comprising the hydrophobic common core) and the set of variable but mutually correlated ones can serve as a basis of having the common 3D structure for rather distinct protein sequences...
- The "what" and "where" of object representations in infancyDenis Mareschal
Centre for Brain and Cognitive Development, School of Psychology, Birkbeck College, University of London, Malet Street, WC1E 7HX London, UK
Cognition 88:259-76. 2003..Our results suggest that it is the target's affordance for action that determines whether the dorsal or ventral information is selectively maintained during occlusion...
- Circular dichroism and synchrotron radiation circular dichroism spectroscopy: tools for drug discoveryB A Wallace
Department of Crystallography, Birkbeck College, University of London, Malet Street, London WC1E 7HX, UK
Biochem Soc Trans 31:631-3. 2003....
- The pH-dependent stability of wild-type and mutant transthyretin oligomersS Skoulakis
Department of Crystallography, Birkbeck College, University of London, UK
Biophys J 84:2795-804. 2003..Certain residues (namely Glu-72, His-88, His-90, Glu-92, and Tyr-116), play an important role in the binding process, as seen by the considerable pK(1/2) change of these residues upon dimer formation...
- 1H NMR spectroscopic studies on the reactions of haloalkylamines with bicarbonate ions: formation of N-carbamates and 2-oxazolidones in cell culture media and blood plasmaM L Anthony
Department of Chemistry, Birkbeck College, University of London, UK
Chem Res Toxicol 8:1046-53. 1995..The ability to form carbamoylated species and OX (or PHOX) may mediate the toxicity of this series of haloalkylamines and hence is potentially of considerable significance...
- BIOPHYSICAL STUDIES OF SRC HOMOLOGY 2 DOMAINSGabriel Waksman; Fiscal Year: 2003..abstract_text> ..
- Structure of Proteins Involved in Bacterial PathogenesisGabriel Waksman; Fiscal Year: 2001..abstract_text> ..
- STRUCTURAL STUDIES OF DNA REPLICATION AND REPAIRGabriel Waksman; Fiscal Year: 1999..Recently, sizable crystals of a DNA/SSBc complex have been grown. ..
- STRUCTURAL STUDIES OF DNA REPLICATION AND REPAIRGabriel Waksman; Fiscal Year: 2003..Such structures will provide information on the mechanism of active unwinding by DNA-helicases and of passive unwinding by helix-destabilizing SSB proteins. ..