Genomes and Genes
University of Liverpool
Organization: University of Liverpool
- Transfusion-transmitted malaria in countries where malaria is endemic: a review of the literature from sub-Saharan AfricaAlex K Owusu-Ofori
Department of Clinical Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana
Clin Infect Dis 51:1192-8. 2010....
- Gene expression markers of tendon fibroblasts in normal and diseased tissue compared to monolayer and three dimensional culture systemsSarah E Taylor
Department of Veterinary Clinical Science, University of Liverpool, Neston, South Wirral, UK
BMC Musculoskelet Disord 10:27. 2009..This study aims to quantify gene expression markers that distinguish between tendon fibroblasts and other mesenchymal cells which may be used to investigate tenogenesis...
- The extradural pressure profile in goats following extradural injectionIsabelle Iff
Clinic for Anaesthesiology and Perioperative Intensive Care, Clinical Department of Small Animals and Horses, Veterinary University, Vienna, Austria
Vet Anaesth Analg 36:180-5. 2009..To measure the extradural pressures in goats before and after extradural injection, and to investigate the occurrence of extradural pressure waves...
- Nonlinear spatial warping for between-subjects pedobarographic image registrationT C Pataky
HACB, University of Liverpool, UK
Gait Posture 29:477-82. 2009..001). These data demonstrate that nonlinear spatial warping is necessary for robust between-subject pedobarographic image registration and, by extension, robust homologous data comparison at the pixel level...
- Planning ahead in public health? A qualitative study of the time horizons used in public health decision-makingDavid C Taylor-Robinson
Division of Public Health, The Whelan Building, Liverpool, UK
BMC Public Health 8:415. 2008..In order to better understand factors that influence decisions for public health, we undertook a qualitative study to explore issues relating to the time horizons used in decision-making...
- Problem-based learning: where are we now?David Taylor
School of Medical Education, University of Liverpool, UK
Med Teach 30:742-63. 2008....
- Prior information and oculomotor initiation: the effect of cues in gapsPaul C Knox
Division of Orthoptics, University of Liverpool, Thompson Yates Building, Brownlow Hill, Liverpool, L69 3GB, UK
Exp Brain Res 192:75-85. 2009....
- Changes in body composition during weight loss in obese client-owned cats: loss of lean tissue mass correlates with overall percentage of weight lostAlexander J German
Small Animal Teaching Hospital, Department of Veterinary Clinical Sciences, University of Liverpool, Chester High Road, Neston, Wirral, UK
J Feline Med Surg 10:452-9. 2008..2%, P=0.026). Conventional weight loss programmes produce safe weight loss, but lean tissue loss is an inevitable consequence in cats that lose significant proportions of their starting body weight...
- Trypanosomosis in The Gambia: prevalence in working horses and donkeys detected by whole genome amplification and PCR, and evidence for interactions between trypanosome speciesGina L Pinchbeck
Faculty of Veterinary Science, University of Liverpool, Leahurst, Neston, CH64 7TE, UK
BMC Vet Res 4:7. 2008....
- Cystic fibrosis and formes frustes of CFTR-related diseaseKevin W Southern
Royal Liverpool Children s Hospital, Institute of Child Health, University of Liverpool, Liverpool, UK
Respiration 74:241-51. 2007..In other cases where a mild CF phenotype is apparent, atypical CF is probably a better term. It remains unclear whether carrier status predisposes to certain conditions such as chronic rhinosinusitis or pancreatitis...
- Arachnoid cyst mimicking normal pressure hydrocephalus. A case report and review of the literatureJ Ramtahal
Walton Centre for Neurology and Neurosurgery, Liverpool, UK
J Neurosurg Sci 50:79-81; discussion 81. 2006..On CT scanning, she is found to have a large arachnoid cyst which mimicked the syndrome of NPH. This is also the 60th published case of arachnoid cyst presenting over the age of 60...
- The complement regulatory proteins CD55 (decay accelerating factor) and CD59 are expressed on the inner acrosomal membrane of human spermatozoa as well as CD46 (membrane cofactor protein)J A Cummerson
Division of Immunology, School of Infection and Host Defence, University of Liverpool, Liverpool, UK
Immunology 118:333-42. 2006..Antibody-induced membrane rafting and release of CD55 & CD59 in vitro may have influenced previous results. Significant coexpression of CD55 & CD46 on the IAM suggests some functional cooperation at this site...
- A model of long-term metabolic progression of type 2 diabetes mellitus for evaluating treatment strategiesAdrian Bagust
University of Liverpool Management School, UK
Pharmacoeconomics 24:5-19. 2006....
- The growing problem of obesity in dogs and catsAlexander J German
Department of Veterinary Clinical Sciences, University of Liverpool, Small Animal Hospital, Liverpool, L7 7EX, UK
J Nutr 136:1940S-1946S. 2006..There is a need to increase the awareness of companion animal obesity as a serious medical concern within the veterinary profession...
- Therapy-related acute leukaemia with Mitoxantrone: what is the risk and can we minimise it?R Ellis
Walton Centre for Neurology and Neurosurgery, Neurological Sciences, Liverpool, UK
Mult Scler 15:505-8. 2009..The timing of this complication, risk, mortality and relationship to exposure remain uncertain...
- The contribution of seizures to psychosocial ill-healthAnn Jacoby
Division of Public Health, University of Liverpool, Whelan Building, The Quadrangle, Brownlow Hill, Liverpool L69 3GB, UK
Epilepsy Behav 15:S41-5. 2009..The need for a more nuanced approach to understanding the causes of psychosocial ill-health is highlighted, as is an important distinction between epilepsy as biomedically defined disease and as socially defined illness...
- Radionuclide transfer to invertebrates and small mammals in a coastal sand dune ecosystemM D Wood
Institute for Sustainable Water Integrated Management and Ecosystem Research School of Biological Sciences, Nicholson Building, University of Liverpool, Liverpool, Merseyside, United Kingdom
Sci Total Environ 407:4062-74. 2009..The lower CRs at the sand dunes may be due to the influence of other cations from the marine environment (e.g. K and Na) on the net radionuclide transfer observed, but further research is required to test this hypothesis...
- "You can't spend years with someone and just cast them aside": augmented identity in older British widowsKate Mary Bennett
School of Psychology, University of Liverpool, Liverpool, UK
J Women Aging 22:204-17. 2010..The reconstructed identity is not that of wife but rather that of an augmented identity of wife/widow. The tensions between how the widows see themselves, and how society sees them are explored...
- Dynamics of longitudinal arch support in relation to walking speed: contribution of the plantar aponeurosisPaolo Caravaggi
Human Anatomy and Cell Biology, School of Biomedical Sciences, University of Liverpool, Liverpool, UK
J Anat 217:254-61. 2010....
- Detection of norovirus in mouthwash samples from patients with acute gastroenteritisAndrew Kirby
School of Infection and Host Defence, University of Liverpool, 8th Floor Duncan Building, Daulby Street, Liverpool L69 3GA, UK
J Clin Virol 48:285-7. 2010..The oral cavity is therefore likely to become contaminated with norovirus during episodes of gastroenteritis...
- 'Waiting until they got home': gender, smoking and tobacco exposure in households in ScotlandJude Robinson
The Health and Community Care Research Unit HaCCRU, University of Liverpool, Thompson Yates Building, The Quadrangle, Brownlow Hill, Liverpool L69 3GB, United Kingdom
Soc Sci Med 71:884-90. 2010..Although home smoking was linked to gendered caring responsibilities, other issues associated with being a smoker also meant that many women smokers chose to keep smoking in their homes...
- Viral respiratory diseases (ILT, aMPV infections, IB): are they ever under control?Richard C Jones
School of Veterinary Science, University of Liverpool, Neston, South Wirral, England, UK
Br Poult Sci 51:1-11. 2010..The importance of constant surveillance is emphasised and the testing of novel vaccines cannot be achieved without the use of vaccine-challenge experiments in poultry...
- Evaluation of housing as a means to protect cattle from Culicoides biting midges, the vectors of bluetongue virusM Baylis
Liverpool University Climate and Infectious Diseases of Animals Group LUCINDA, Department of Veterinary Clinical Science, University of Liverpool, Neston, UK
Med Vet Entomol 24:38-45. 2010..The results suggest that the risk of animals receiving bites from C. obsoletus is reduced by housing at both times of year and the benefit would be greatest on warm, still nights when outside catches are at their greatest...
- Distinct roles for Caf1, Ccr4, Edc3 and CutA in the co-ordination of transcript deadenylation, decapping and P-body formation in Aspergillus nidulansIgor Y Morozov
School of Biological Sciences, The University of Liverpool, Crown Street, Liverpool L69 7ZB, UK
Mol Microbiol 76:503-16. 2010..As with DeltacutA, Deltaedc3 led to reduced rates of transcript degradation. These data link P-bodies to both the optimization and regulation of transcript degradation...
- Undergraduate training in palliative medicine: is more necessarily better?Stephen R Mason
Marie Curie Palliative Care Institute Liverpool, UK
Palliat Med 24:306-9. 2010The General Medical Council's call to modernize medical education prompted the University of Liverpool Medical School to develop a new undergraduate programme, integrating palliative medicine as 'core' curricula...
- Can central hexagon peak latency provide a clue to fixation within the mfERGR P Hagan
Department of Medical Physics and Clinical Engineering, Royal Liverpool University Hospital, Liverpool, L7 8XP, UK
Doc Ophthalmol 120:159-64. 2010..This study suggests that latency could provide a clue to fixation particular at slow rates thereby improving the quality and confidence of recordings made clinically...
- Cementoblastoma in the maxilla: a case reportGillian L Barker
Liverpool University Dental School, Liverpool, UK
Prim Dent Care 16:154-6. 2009..It also serves as a reminder that rare odontogenic tumours may present initially in primary care and it is essential that all practitioners are aware of them...
- The diagnostic and prognostic accuracy of five markers of serious bacterial infection in Malawian children with signs of severe infectionEnitan D Carrol
Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi
PLoS ONE 4:e6621. 2009....
- Cellularity and apparent diffusion coefficient in oligodendroglial tumours characterized by genotypeMichael D Jenkinson
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool, L9 7LJ, UK
J Neurooncol 96:385-92. 2010..This study evaluated the relationship between ADC and tumour cellularity in oligodendroglial tumours characterized by genotype...
- Confidence intervals for the volume of brain structures in Cavalieri sampling with local errorsMarta Garcia-Finana
Centre for Medical Statistics and Health Evaluation, University of Liverpool, Shelley s Cottage, Liverpool, UK
J Neurosci Methods 179:71-7. 2009..Finally, the new approach is applied to investigate the significance of hippocampus volume change in a patient with epilepsy after 2 years of disease...
- Biofilm structure and cell vitality in a laboratory model of subgingival plaqueC K Hope
Division of Microbial Diseases, Eastman Dental Institute, University College London, London, UK
J Microbiol Methods 66:390-8. 2006..The reasons for the preponderance of nonviable bacteria in the outer layer of the bacterial stacks remain to be established...
- Catastrophic fracture of the lateral condyle of the third metacarpus/metatarsus in UK racehorses - fracture descriptions and pre-existing pathologyT D H Parkin
Department of Veterinary Clinical Science, University of Liverpool Veterinary Teaching Hospital, Leahurst, Neston CH64 7TE, UK
Vet J 171:157-65. 2006..The degree of this pathology was not associated with horse age, length of career or number of career starts...
- Comparison of direct and indirect tests for small intestinal bacterial overgrowth and antibiotic-responsive diarrhea in dogsA J German
Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol, UK
J Vet Intern Med 17:33-43. 2003..These results question the utility of quantitative duodenal juice bacteriology and indirect biochemical marker tests for SIBO in the investigation of canine gastrointestinal disorders...
- Insulin-treated diabetes and driving in the UKG Gill
Department of Diabetes and Endocrinology, University Hospital Aintree, Liverpool, UK
Diabet Med 19:435-9. 2002..Diabetes and insulin-treated diabetes is an emotive and difficult issue, for which a stronger evidence base is urgently needed...
- Managing the entry of new medicines in the National Health Service: health authority experiences and prospects for primary care groups and trustsR McDonald
Prescribing Research Group, Department of Pharmacology and Therapeutics, University of Liverpool, 70 Pembroke Place, Liverpool L69 3GF, UK
Health Soc Care Community 9:341-7. 2001..The tensions between local priority setting, which may mean saying no to new medicines, whilst at the same time eradicating postcode prescribing and balancing budgets means that PCG/Ts face difficult policy choices...
- Evidence for memorized site-fidelity in Anopheles arabiensisP J McCall
Division of Parasite and Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
Trans R Soc Trop Med Hyg 95:587-90. 2001..The effects of the observed behaviours on malaria epidemiology are discussed...
- Molecular pathogenesis of pancreatic ductal adenocarcinoma and clinical implicationsC J Magee
University of Liverpool, Department of Surgery, 5th Floor UCD Building, Royal Liverpool University Hospital, Daulby Street, Liverpool L69 3GA, UK
Surg Oncol 10:1-23. 2001..This review is concerned with the molecular pathogenesis of PDAC and the application of this basic scientific understanding into state-of-the-art clinical practice...
- Learning gross anatomy in a clinical skills courseP Dangerfield
Department of Human Anatomy and Cell Biology, The University of Liverpool, United Kingdom
Clin Anat 13:444-7. 2000..Students take responsibility for their own learning, with appropriate support and resources. In clinical skills courses, anatomy underpins the development and retention of clinical knowledge and skills...
- Problems posed by natural environments for monitoring microorganismsC Edwards
School of Biological Sciences, University of Liverpool, UK
Mol Biotechnol 15:211-23. 2000....
- COPD: early detection and interventionP M Calverley
University Clinical Departments, University Hospital Aintree, Long Lane, Liverpool, United Kingdom
Chest 117:365S-71S. 2000..In this article, some of the important concepts relevant to this process are considered, and some of the present techniques used to intervene in established COPD are reviewed...
- The effect of inositol 1,3,4,5-tetrakisphosphate on inositol trisphosphate-induced Ca2+ mobilization in freshly isolated and cultured mouse lacrimal acinar cellsP M Smith
Department of Clinical Dental Sciences, University of Liverpool, Liverpool L69 3BX, U K
Biochem J 347:77-82. 2000....
- Suppression of oxytocin-induced prostaglandin F2alpha release after intra-uterine nordihydroguariaretic acid administration in ewesR G Cooke
Department of Veterinrary Preclinical Sciences, University of Liverpool, Cheshire, United Kingdom
Prostaglandins Other Lipid Mediat 60:27-33. 2000..01) in the nordihydroguariaretic acid-treated ewes (218+/-60 vs. 579+/-66 fmol/mg tissue). These results suggest that 5-lipoxygenase products of arachidonate metabolism may be involved in the control of ovine luteal function...
- The use of electronic mail in biomedical communicationR Costello
Department of Medicine, University of Liverpool, University Hospital Aintree, United Kingdom
J Am Med Inform Assoc 7:103-5. 2000..To determine whether there are statistically significant differences in the content of electronic mail (e-mail) and conventional mail sent to authors of papers published in medical journals...
- Transmission control and drug resistance in malaria: a crucial interactionD H Molyneux
Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, UK
Parasitol Today 15:238-40. 1999..Modelling the many parameters that impact on this complex relationship will better inform policy makers...
- Calcium-binding protein S100A4 in health and diseaseR Barraclough
School of Biological Sciences, University of Liverpool, UK
Biochim Biophys Acta 1448:190-9. 1998..Possible mechanisms for the metastasis-inducing effect of S100A4 and the relevance of these observations to human cancer are discussed...
- Are proximal colorectal cancers always associated with distal adenomas?A J M Watson
Department of Medicine, University of Liverpool, Daulby St, Liverpool L69 3GA, UK
Gut 52:317-8. 2003
- Common themes in changing vector-borne disease scenariosDavid H Molyneux
Lymphatic Filariasis Support Centre, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
Trans R Soc Trop Med Hyg 97:129-32. 2003..vivax ratios and well-described land use changes such as hydrological, urbanization, agricultural, mining and forest-associated impacts (extractive activities, road building, deforestation and migration) which are seen on a global scale...
- Pseudoainhum in chronic psoriasisS L Almond
Department of Plastic Surgery, Whiston Hospital, Prescot Road, Merseyside, L35 5DR, UK
Br J Dermatol 149:1064-6. 2003..Progression of the lesions can cause irreversible damage and autoamputation of the affected digit. This report documents a rare association of pseudoainhum and psoriasis and emphasizes the importance of recognizing this condition...
- Ca2+ signalling and pancreatitis: effects of alcohol, bile and coffeeOle H Petersen
MRC Group, Physiological Laboratory and Division of Surgery and Oncology, University of Liverpool, Liverpool L69 3BX, UK
Trends Pharmacol Sci 27:113-20. 2006..These abnormal Ca2+ signals, which can be inhibited by caffeine, explain how excessive alcohol intake and biliary disease cause acute pancreatitis, an often-fatal human disease in which the pancreas digests itself and its surroundings...
- Analytical and physiological factors affecting the interpretation of serum testosterone concentration in menM J Diver
Department of Clinical Biochemistry and Metabolic Medicine, Royal Liverpool University Hospital, Prescot Street, Liverpool L7 8XP, UK
Ann Clin Biochem 43:3-12. 2006....
- Dynamic mechanical allodynia in neuropathic painDavid Bowsher
Pain Research Institute, Clinical Sciences Building, University Hospital Aintree, Liverpool L9 7AL, UK
Pain 116:164-5. 2005..The findings have implications for diagnosis, and require pathophysiological elucidation in terms of revealed differences...
- Evaluation of the clinical efficacy of prokinetic drugs in the management of post-operative ileus: can retrospective data help us?M A Smith
Equine Division, Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool, Leahurst, Neston, Wirral, Liverpool CH64 7TE, UK
Vet J 170:230-6. 2005..This report illustrates difficulties with performing retrospective analysis of clinical data to determine the efficacy of treatment regimes...
- Impact of epilepsy in adolescence: a UK controlled studyGus A Baker
Department of Neurological Science, University of Liverpool, Walton Hospital, Liverpool, UK
Epilepsy Behav 6:556-62. 2005....
- Effects of cold storage on detection of avian infectious bronchitis virus in chicken carcasses and local antibodies in tracheal washesKannan Ganapathy
Department of Veterinary Pathology, University of Liverpool, Leahurst, Neston, South Wirral CH64 7TE, UK
J Virol Methods 126:87-90. 2005..Levels of IgA in tracheal washes remained high for up to 9 h of storage, suggesting that accurate sampling for research purposes when required must be carried out within this time...
- Investigating heterogeneity in an individual patient data meta-analysis of time to event outcomesCatrin Tudur Smith
Centre for Medical Statistics and Health Evaluation, University of Liverpool, Liverpool L69 3BX, UK
Stat Med 24:1307-19. 2005..The models are further applied to simulated data examples in which the degree of heterogeneity and magnitude of treatment effect are varied. The behaviour of each model in each situation is explored and compared...
- Developing rat lung has a sided pacemaker region for morphogenesis-related airway peristalsisEdwin C Jesudason
Paediatric Surgery, Institute of Child Health, Alder Hey Children s Hospital, Eaton Road, Liverpool L12 2AP, UK
Am J Respir Cell Mol Biol 32:118-27. 2005..Airway peristalsis may be crucial for lung development (thereby providing a physiologic role for airway smooth muscle) and play a hitherto unanticipated role in reported transgenic mutant lung phenotypes...
- Congenital phimosis in a catS R Bright
Ashleigh Veterinary Centre, 221 Upper Chorlton Road, Whalley Range, Manchester M16 0DE, UK
J Feline Med Surg 6:367-70. 2004..The procedure was quick, easy to perform and led to a resolution of the occasional bouts of haematuria and pollakiuria...
- Apoptosis and colorectal cancerA J M Watson
Department Medicine, University of Liverpool Medical School, Daulby St, Liverpool L69 3GA, UK
Gut 53:1701-9. 2004
- Design and synthesis of endoperoxide antimalarial prodrug modelsPaul M O'Neill
Department of Chemistry, The Robert Robinson Laboratories, University of Liverpool, Liverpool L69 7ZD, UK
Angew Chem Int Ed Engl 43:4193-7. 2004
- Wolbachia and cytoplasmic incompatibility in mosquitoesSteven P Sinkins
Vector Research Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
Insect Biochem Mol Biol 34:723-9. 2004....
- 1H chemical shifts in NMR. Part 20--anisotropic and steric effects in halogen substituent chemical shifts (SCS), a modelling and ab initio investigationRaymond J Abraham
Chemistry Department, University of Liverpool, P O Box 147, Liverpool L69 3BX, UK
Magn Reson Chem 42:436-44. 2004..m.s. errors and the CHARGE program was shown to be more accurate for the compounds considered here than the other two methods. The different philosophies of these programs are discussed together with the results obtained...
- Factors affecting the development of carious lesions in bovine teeth in vitroB T Amaechi
Department of Clinical Dental Sciences, The University of Liverpool, England
Arch Oral Biol 43:619-28. 1998..It was concluded that caries-like lesions can be consistently produced in bovine enamel with a partially saturated acidic buffer solution at 20 degrees C or 37 degrees C within 3 days...
- Institutional Collaboration Between Liverpool STM & CDC on MalariaFeiko ter Kuile; Fiscal Year: 2007..The secretariat will be based at the LSTM. ..