University College London
Organization: University College London
- Detection of the cardiovascular complications of thalassemia by echocardiographyJohn Malcolm Walker
Hatter Cardiovascular Institute, University College Hospital, London, United Kingdom
Ann N Y Acad Sci 1202:165-72. 2010..It is particularly suited to assess diastolic function, diagnose intracardiac masses (usually thrombus), and assess right ventricular function and pulmonary pressure...
- Oral bisphosphonates and risk of atrial fibrillation and flutter in women: a self-controlled case-series safety analysisAnthony Grosso
Department of Pharmacy, University College London Hospitals NHS Foundation Trust, London, United Kingdom
PLoS ONE 4:e4720. 2009..Two subsequent population-based case-control studies of patients receiving a more established oral bisphosphonate, alendronic acid, reported conflicting results, possibly due to uncontrolled confounding factors...
- Experimental therapies in Ewing's sarcomaRachael Windsor
The London Sarcoma Service, UCL Hospitals NHS Foundation Trust, First Floor Central, 250 Euston Road, NW1 2PG, London, UK
Expert Opin Investig Drugs 18:143-59. 2009..With current treatments, significant numbers of patients relapse and survival is poor for those with metastatic disease...
- A tertiary experience of vesico-vaginal and urethro-vaginal fistula repair: factors predicting successJeremy L Ockrim
Institute of Urology, University College London Hospital, London, UK
BJU Int 103:1122-6. 2009..To review the outcomes of all patients referred with vesico-vaginal (V VF) and urethro-vaginal (UVF) fistulae to a tertiary centre, and to investigate the patient, fistula and surgical factors relevant to success...
- Pharyngeal residue across the lifespan: a first look at what's normalA M Kelly
Head and Neck Centre, University College London Hospitals NHS Foundation Trust, London, UK
Clin Otolaryngol 33:348-51. 2008..Without good evidence, post-swallow pharyngeal residue is considered abnormal. Our aim was to document residue from normal food and fluid boluses in young and elderly healthy populations...
- Comparison of gemcitabine and carboplatin versus cisplatin and etoposide for patients with poor-prognosis small cell lung cancerS M Lee
Department of Oncology, University College Hospital, London, UK
Thorax 64:75-80. 2009..This non-inferiority design trial aimed to determine whether the combination of gemcitabine and carboplatin (GC) results in similar survival but is less toxic with better quality of life...
- The use of implants at an increased vertical dimension of occlusion to correct a scissor bite: a case reportGwen Benny Wilson
Eur J Prosthodont Restor Dent 16:67-72. 2008..The importance of a multi-disciplinary approach to planning and close liaison between the orthodontist, surgeon and restorative dentist during the treatment phase are discussed...
- Emotional support given by ward-based nurses to sarcoma patientsJennifer Spears
Department of Oncology, University College London Hospitals NHS Foundation Trust, 235 Euston Road, London NW1 2BU, UK
Eur J Oncol Nurs 12:334-41. 2008..This study explored the emotional support, as perceived by patients, that ward nurses give to sarcoma patients at a large cancer centre...
- Neurological picture. Varicella zoster virus and intracranial dolichoectasia in a late adult cancer survivorC M Dalton
Acute Stroke and Brain Injury Service, The National Hospital for Neurology and Neurosurgery, London WC1N 3BG, UK
J Neurol Neurosurg Psychiatry 79:573. 2008
- Sugar rush: the early days of molecular imagingPeter J Ell
Institute of Nuclear Medicine, University College London Hospitals NHS Trust, London, UK
Lancet Oncol 9:400. 2008
- Poor accrual of teenagers and young adults into clinical trials in the UKJeremy S Whelan
Department of Oncology, University College Hospital, London
Lancet Oncol 9:306-7. 2008
- Emerging chemotherapeutic strategies and the role of treatment stratification in Ewing sarcomaBeatrice M Seddon
London Bone and Soft Tissue Tumor Service, University College Hospital, London, UK
Paediatr Drugs 10:93-105. 2008....
- Role of FDG PET in the management of childhood lymphomas--case proven or is the jury still out?Ananth Shankar
Department of Paediatric and Adolescent Oncology, 6th Floor Central, University College London Hospitals NHS Foundation Trust, 250 Euston Road, London, UK
Eur J Cancer 44:663-73. 2008..Specific attention is focused on the clinical circumstances in which FDG PET is most likely to have an impact on management and some indications for its use in childhood lymphomas are suggested...
- The role of recombinant erythropoietin in childhood cancerAnanth Gouri Shankar
Department of Paediatric and Adolescent Oncology, University College London Hospitals NHS Foundation Trust, London, NW1 2PG, United Kingdom
Oncologist 13:157-66. 2008..This review critically evaluates the published evidence of its use in childhood cancer especially; its safety and efficacy in the prevention and treatment of CAA and some indications for its use in childhood cancer are suggested...
- Investigation of the effect of a proprietary dental waterline disinfectant on shear bond strengths of Panavia 21 to enamel and dentineK Patel
University College London, Eastman Dental Institute
Eur J Prosthodont Restor Dent 17:41-6. 2009..There was no significant difference in shear bond strengths for both enamel and dentine with Alpron mint irrigation compared with distilled water (P = 0.245)...
- Management of related donor care: a European surveyS Clare
Department of Clinical Haematology, Haematology Nursing Research and Practice Development, University College Hospital, University College London Hospitals NHS Foundation Trust, London, UK
Bone Marrow Transplant 45:97-101. 2010..The development of such guidelines would assist in maintaining patient autonomy, confidentiality and access to accurate and objective information...
- The impact of reconstruction method on the quantification of DaTSCAN imagesJohn C Dickson
Institute of Nuclear Medicine, UCLH NHS Foundation Trust and University College London, London, UK
Eur J Nucl Med Mol Imaging 37:23-35. 2010..This study assessed the impact of the number of iterations on the image quantification, comparing the results of the iterative reconstruction with filtered back-projection data...
- T-cell-depleted reduced-intensity transplantation followed by donor leukocyte infusions to promote graft-versus-lymphoma activity results in excellent long-term survival in patients with multiply relapsed follicular lymphomaKirsty J Thomson
Department of Haematology, University College Hospital, London, UK
J Clin Oncol 28:3695-700. 2010..Thus, reduced-intensity conditioning regimens are being explored...
- The use of adenosine triphosphate bioluminescence to assess the efficacy of a modified cleaning program implemented within an intensive care settingGinny Moore
Department of Microbiology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
Am J Infect Control 38:617-22. 2010..A total environmental cleaning system based on microfiber technology was implemented within 2 intensive care units (ICUs). The efficacy of this modified cleaning program was assessed using adenosine triphosphate (ATP) bioluminescence...
- Mitochondrial DNA targets increase sensitivity of malaria detection using loop-mediated isothermal amplificationSpencer D Polley
Department of Clinical Parasitology, Hospital for Tropical Diseases, London Hospitals University College NHS Foundation Trust, Mortimer Market, Capper Street, London WC1E 6JB, United Kingdom
J Clin Microbiol 48:2866-71. 2010....
- Simultaneous dual-radionuclide myocardial perfusion imaging with a solid-state dedicated cardiac cameraSimona Ben-Haim
Institute of Nuclear Medicine, University College London Hospitals NHS Trust, London, UK
Eur J Nucl Med Mol Imaging 37:1710-21. 2010..We compared simultaneous dual-radionuclide (DR) stress and rest myocardial perfusion imaging (MPI) with a novel solid-state cardiac camera and a conventional SPECT camera with separate stress and rest acquisitions...
- The potential for mixed multiplexed and non-multiplexed data to improve the reconstruction quality of a multi-slit-slat collimator SPECT systemShelan T Mahmood
Institute of Nuclear Medicine, UCL and UCLH NHS Foundation Trust, London, UK
Phys Med Biol 55:2247-68. 2010..This gain in the SNR corresponds to a 75% increase in counts or sensitivity which can be utilized to reduce acquisition time, patient dose or/and improve image quality...
- Antithrombotic treatment failures in antiphospholipid syndrome: the new anticoagulants?H Cohen
Department of Haematology, University College London, London, UK
Lupus 19:486-91. 2010..Here, we summarize current indications for these agents and address the potential for their use in patients with thrombotic APS...
- Serum 25-hydroxy vitamin D levels in chronic fatigue syndrome: a retrospective surveySaul Berkovitz
Royal London Homeopathic Hospital, University College London Hospitals NHS Trust, London, UK
Int J Vitam Nutr Res 79:250-4. 2009..We hypothesized that serum 25-OH vitamin D levels are lower in CFS patients than in the general British population...
- Brain-water diffusion coefficients reflect the severity of inherited prion diseaseH Hyare
National Prion Clinic, Box 98, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK, WC1N 3BG
Neurology 74:658-65. 2010..We wished to assess the potential of diffusion-weighted MRI as a biomarker of disease severity in inherited prion diseases...
- The myotonic dystrophies: diagnosis and managementChris Turner
Department of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
J Neurol Neurosurg Psychiatry 81:358-67. 2010....
- The modern investigation and management of gastro-oesophageal reflux disease (GORD)Matthew Banks
University College London
Clin Med 9:600-4. 2009..Most patients do not require investigation and respond either to lifestyle changes, antacid/alginates, H2A, PPI or a combination of these treatments. Surgery is only rarely indicated...
- Wound management and restrictive arm movement following cardiac device implantation - evidence for practice?Katrine Bavnbek
The Heart Hospital, University College London Hospitals, UK
Eur J Cardiovasc Nurs 9:85-91. 2010..No national/international guidelines address postoperative care and controversy exists regarding wound management and arm movement following cardiac device implantation...
- Right to left shunt following radiofrequency catheter ablation of atrial fibrillation in a patient with complex congenital heart diseaseJames W McCready
The Heart Hospital, University College Hospital, UCL, London W1G 8PH, UK
Europace 12:289-90. 2010..Post procedure the patient became cyanosed with right to left shunting. Transcatheter closure immediately improved symptoms and oxygen saturation...
- Use of ultrasound pattern recognition by expert operators to identify borderline ovarian tumors: a study of diagnostic performance and interobserver agreementJ Yazbek
Early Pregnancy and Gynaecology Assessment Unit, King s College Hospital, London, UK
Ultrasound Obstet Gynecol 35:84-8. 2010..To assess the accuracy and reproducibility of ultrasound 'pattern recognition' for the diagnosis of borderline ovarian tumors by asking experienced ultrasound operators to evaluate representative images of different types of adnexal tumor...
- Oral healthcare for HIV-infected patients: an international perspectiveA M Hegarty
UCL Eastman Dental Institute and UCLHT Eastman Dental Hospital, Unit of Oral Medicine, 256 Grey s Inn Road, London, WC1X 8LD, UK
Expert Opin Pharmacother 9:387-404. 2008..These will inform treatment protocols tailored to these locations. This review highlights the international variance in therapeutic intervention for HIV-related orofacial disease...
- Depression in adults with Fabry disease: a common and under-diagnosed problemA L Cole
Charles Dent Metabolic Unit, Box 92, The National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N3BG, UK
J Inherit Metab Dis 30:943-51. 2007..Depression in adults with AFD has been reported, but no large study has been done. We have examined the adult Fabry population in the United Kingdom to describe the prevalence, associated factors and frequency of diagnosis of depression...
- Evaluation of specific and non-specific effects in homeopathy: feasibility study for a randomised trialPeter Fisher
Royal London Homoeopathic Hospital, London, UK
Homeopathy 95:215-22. 2006....
- Management of urethral stricturesA R Mundy
The Institute of Urology, London, 2A Maple House, Ground Floor, Rosenheim Wing, 25 Grafton Way, London WC1E 6AU, UK
Postgrad Med J 82:489-93. 2006..Although this review is therefore inevitably biased, it is unlikely that expert opinion will take issue with most of the general points raised here...
- An epidemiological evaluation of risk factors for tuberculosis in South India: a matched case control studyN Shetty
Department of Clinical Microbiology, Health Protection Agency Collaborating Centre, University College London Hospitals, 1st Floor, Windeyer Institute of Medical Sciences, 46 Cleveland Street, London W1T 4JF, United Kingdom
Int J Tuberc Lung Dis 10:80-6. 2006..There are limited data on risk factors associated with tuberculosis (TB) in India...
- Homeopathy and mainstream medicine: a dialogue of the deaf?Peter Fisher
Royal London Homoeopathic Hospital, London, United Kingdom
Wien Med Wochenschr 155:474-8. 2005..The Royal London Homoeopathic Hospital is developing clinical integration and scientific collaboration with a major academic medical centre in London...
- Review article: complementary and alternative therapies for inflammatory bowel diseaseL Langmead
Department of Gastroenterology, University College London Hospitals, NHS Foundation Trust, London, UK
Aliment Pharmacol Ther 23:341-9. 2006..There is a need for further controlled clinical trials of the potential efficacy of complementary and alternative approaches in inflammatory bowel disease, together with enhanced legislation to maximize their quality and safety...
- Evaluation of three commercial agar preparations for the presumptive identification of significant urinary isolatesK I Miles
Microbiology Department, University College London Hospitals Trust, Windeyer Institute, UK
Br J Biomed Sci 62:179-81. 2005..Chromogenic media are richer than CLED and a number of Lactobacillus spp. (normally regarded as normal flora) grew on this medium. These were not considered to be significant...
- A new protein substitute for adolescents and adults with maple syrup urine disease (MSUD)P Hallam
The Charles Dent Metabolic Unit, The National Hospital for Neurology and Neurosurgery, University College Hospitals NHS Trust, London, UK
J Inherit Metab Dis 28:665-72. 2005..The aim was to study the efficacy and acceptability of MSUD Express in adolescent and adult patients with maple syrup urine disease (MSUD)...
- Caspofungin in the treatment of invasive fungal infectionsSimon Keady
Women and Children s Services, University College London Hospitals NHS Foundation Trust, UK
Intensive Crit Care Nurs 22:59-62. 2006..The article also discusses the warnings and precautions associated with the use of this drug. Caspofungin is an effective treatment option in the management of fungal infections...
- Prevalence of Fusobacterium necrophorum and other upper respiratory tract pathogens isolated from throat swabsA Batty
Department of Clinical Microbiology, University College London Hospitals, Windeyer Institute of Medical Sciences, 46 Cleveland Street, London W1T 4JF
Br J Biomed Sci 62:66-70. 2005..However, based on the clinical symptoms routinely provided by clinicians requesting microscopy, culture and sensitivity on throat swabs, F. necrophorum culture is required on all throat swabs received in the laboratory...
- Hooray for hypoxia?Geoff Bellingan
Department of Critical Care, University College Hospitals, London, United Kingdom
PLoS Med 2:e130. 2005
- Congenital heart disease in pregnancyC E G Head
Department of Cardiology, University Hospital, Birmingham, UK
Postgrad Med J 81:292-8. 2005..The optimum management of a pregnant woman with a metallic prosthetic valve remains to be determined...
- Effectiveness gaps: a new concept for evaluating health service and research needs applied to complementary and alternative medicinePeter Fisher
Royal London Homoeopathic Hospital, London, UK
J Altern Complement Med 10:627-32. 2004..Complementary and alternative medicine (CAM) interventions, by definition, are not generally available through normal health care channels. Therefore, if effective, they have the potential to increase achieved community effectiveness...
- Evaluation of mutation screening as a first line test for the diagnosis of the primary hyperoxaluriasGill Rumsby
Clinical Biochemistry, UCL Hospitals, London, United Kingdom
Kidney Int 66:959-63. 2004..We have evaluated a molecular genetic approach for the diagnosis of these autosomal-recessive diseases...
- Frequency of metabolic disorders: more than one needle in the haystackP J Lee
Charles Dent Metabolic Unit, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
Arch Dis Child 91:879-80. 2006
- Diagnosing pancreatic cancer: the role of percutaneous biopsy and CTZ Amin
Department of Imaging, University College Hospital, London, UK
Clin Radiol 61:996-1002. 2006..To determine the sensitivity and complications of percutaneous biopsy of pancreatic masses, and whether typical computed tomography (CT) features of adenocarcinoma can reliably predict this diagnosis...
- Free phenytoin concentration measurement in brain extracellular fluid: a pilot studyM Tisdall
Department of Neuroanaesthesia and Neurocritical Care, National Hospital for Neurology and Neurosurgery, London, UK
Br J Neurosurg 20:285-9. 2006..This has implications for dosing regimens relying on plasma phenytoin levels...
- A review of the aetiology and management of fractured dental implants and a case reportP Virdee
Department of Periodontology, Eastman Dental Hospital, 256 Gray s Inn Road, London, WC1X 8LD
Br Dent J 203:461-6. 2007..The likely causes are discussed and the treatment options highlighted together with the decision making process which lead to the final management...
- The impact of the introduction of critical care outreach services in England: a multicentre interrupted time-series analysisHaiyan Gao
Intensive Care National Audit and Research Centre, Tavistock House, Tavistock Square, London WC1H 9HR, UK
Crit Care 11:R113. 2007..We undertook a multicentre interrupted time-series analysis of the impact of CCOS, as characterised by the case mix, outcome and activity of admissions to adult, general critical care units in England...
- Intensive care management of patients with subarachnoid haemorrhageMartin Smith
National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London, UK
Curr Opin Anaesthesiol 20:400-7. 2007....
- Review of NICE guidelines on routine postnatal infant careM Sellwood
University College London Hospitals NHS Foundation Trust, London, UK
Arch Dis Child Fetal Neonatal Ed 93:F10-3. 2008
- Three novel highly charged copper-based biocides: safety and efficacy against healthcare-associated organismsVanya A Gant
Department of Microbiology, University College Hospitals NHS Foundation Trust, London W1T 4JF, UK
J Antimicrob Chemother 60:294-9. 2007..We investigated three novel highly charged copper-based inorganic biocidal formulations for their activity against organisms highly relevant to healthcare-associated infection...
- Requests for cosmetic genitoplasty: how should healthcare providers respond?Lih Mei Liao
Middlesex Centre, UCL Institute for Women s Health, Elizabeth Garrett Anderson and Obstetric Hospital, London WC1E 6DH
BMJ 334:1090-2. 2007
- A novel starch for the treatment of glycogen storage diseasesK Bhattacharya
Charles Dent Metabolic Unit, National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK
J Inherit Metab Dis 30:350-7. 2007..To determine whether a new starch offers better short-term metabolic control than uncooked cornstarch in patients with glycogen storage diseases (GSDs)...
- Endovascular management of major arterial hemorrhage as a complication of inflammatory pancreatic diseaseHarpreet Hyare
Department of Radiology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
J Vasc Interv Radiol 18:591-6. 2007....
- Guidelines for the use of imaging in the management of myelomaShirley D'Sa
Department of Haematology, University College Hospital, London, UK
Br J Haematol 137:49-63. 2007..These stand-alone imaging guidelines discuss recommendations for the use of each modality of imaging at diagnosis and in the follow up of patients with myeloma...
- Localised periodontitis associated with an ectopic orthodontic separatorZoe Harrington
Department of Periodontology, Eastman Dental Hospital, London, UK
Prim Dent Care 14:5-6. 2007..The presence of this object was related to quite severe periodontal breakdown around an upper right first premolar tooth in an otherwise unsusceptible individual...
- The heat stability of Plasmodium lactate dehydrogenase-based and histidine-rich protein 2-based malaria rapid diagnostic testsPeter L Chiodini
Department of Clinical Parasitology, Hospital for Tropical Diseases, London, UK
Trans R Soc Trop Med Hyg 101:331-7. 2007..The performance of malaria RDTs can be adversely affected at the temperatures to which they will be exposed when transported to, and used in, the rural tropics...
- Immunizing patients with systemic lupus erythematosus: a review of effectiveness and safetyS G O'Neill
Centre for Rheumatology, University College London, London, UK
Lupus 15:778-83. 2006..The majority of patients appear to have a reasonable serological response to vaccination...
- Incontinence after brain injury: prevalence, outcome and multidisciplinary management on a neurological rehabilitation unitS M Leary
Regional Neurological Rehabilitation Unit, Homerton University Hospital and National Hospital for Neurology and Neurosurgery, University College London Hospitals, Queen Square, London, UK
Clin Rehabil 20:1094-9. 2006..To investigate the prevalence, outcome and multidisciplinary management of incontinence in patients with acquired brain injury...
- Reforming clinical research and development in EnglandNick McNally
University College London Hospitals NHS Trust, London NW1 2LT
BMJ 327:550-3. 2003