J D Steele
- Segregation of cognitive and emotional function in the prefrontal cortex: a stereotactic meta-analysisJ D Steele
Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh EH10 5HF, UK
Neuroimage 21:868-75. 2004..Such estimates of most likely reported activation loci may allow improved planning, analysis, and interpretation of imaging studies of psychiatric disorder and of normal function...
- Neural predictive error signal correlates with depressive illness severity in a game paradigmJ D Steele
Department of Mental Health, University of Aberdeen, Aberdeen, AB25 2ZH, UK
Neuroimage 23:269-80. 2004..Again, differences were found that in some cases correlated with illness severity. These results are discussed in the context of quantitative theories of brain function, clinical features of depressive illness and treatments...
- Abnormal temporal difference reward-learning signals in major depressionP Kumar
Department of Mental Health, University of Aberdeen, Aberdeen AB25 2ZH, UK
Brain 131:2084-93. 2008....
- Blunted response to feedback information in depressive illnessJ D Steele
Department of Mental Health, University of Aberdeen, Royal Cornhill Hospital, Aberdeen AB25 2ZH, UK
Brain 130:2367-74. 2007..Our results suggest a direct link between the core subjective symptom of anhedonia, replicated neuropsychological deficits, electrophysiological and imaging abnormalities, and hypothesized dysfunction of the error correction system...
- Possible structural abnormality of the brainstem in unipolar depressive illness: a transcranial ultrasound and diffusion tensor magnetic resonance imaging studyJ D Steele
Department of Mental Health, University of Aberdeen, Royal Cornhill Hospital, UK
J Neurol Neurosurg Psychiatry 76:1510-5. 2005..This may be consistent with disruption of white matter tracts, including the medial forebrain bundle, and it has been suggested that the effect of such disruption could be reversed by antidepressants...
- Connecting the brain and new drug targets for schizophreniaH C Whalley
Division of Psychiatry, University of Edinburgh, Edinburgh, Scotland, UK
Curr Pharm Des 15:2615-31. 2009..We conclude that substantial work needs to be done on standardising connectivity analyses across laboratories and that disconnectivity studies should be an integral part of drug discovery programmes...