- Conditional lethality of the diprotic weak bases chloroquine and quinacrine against Cryptococcus neoformansT S Harrison
Department of Infectious Diseases, Division of Cellular and Molecular Sciences, St George s Hospital Medical School, London SW17 ORE, United Kingdom
J Infect Dis 182:283-9. 2000..These findings add to the known spectrum of activity of chloroquine and quinacrine. These, and related compounds, may have utility for the treatment of cryptococcosis...
- Determination of the pH of the Cryptococcus neoformans vacuoleT S Harrison
Department of Infectious Diseases, St George s Hospital Medical School, London, UK
Med Mycol 40:329-32. 2002..Antifungal activity may result from the consequent disruption of pH-dependent processes as well as effects on other as yet undefined fungal targets...