P Harnden

Summary

Affiliation: St James's University Hospital
Country: UK

Publications

  1. doi request reprint Evaluation of the use of digital images for a national prostate core external quality assurance scheme
    Patricia Harnden
    Histopathology, Leeds Teaching Hospitals NHS Trust, St James s University Hospital, Leeds, UK
    Histopathology 59:703-9. 2011
  2. doi request reprint Does the extent of carcinoma in prostatic biopsies predict prostate-specific antigen recurrence? A systematic review
    Patricia Harnden
    Cancer Research UK Clinical Centre, St James s University Hospital, Beckett Street, Leeds, United Kingdom
    Eur Urol 54:728-39. 2008
  3. doi request reprint Prostatic pathology reporting in the UK: development of a national external quality assurance scheme
    P Harnden
    Cancer Research UK Clinical Centre, St James s University Hospital, Leeds, UK
    Histopathology 52:147-57. 2008
  4. ncbi request reprint The prognostic significance of perineural invasion in prostatic cancer biopsies: a systematic review
    Patricia Harnden
    Cancer Research UK Clinical Centre, St James s University Hospital, Leeds, United Kingdom
    Cancer 109:13-24. 2007
  5. ncbi request reprint A critical appraisal of the classification of urothelial tumours: time for a review of the evidence and a radical change?
    Patricia Harnden
    Leeds Teaching Hospitals NHS Trust, St James s University Hospital, Leeds, UK
    BJU Int 99:723-5. 2007
  6. doi request reprint The clinical management of patients with a small volume of prostatic cancer on biopsy: what are the risks of progression? A systematic review and meta-analysis
    Patricia Harnden
    Cancer Research United Kingdom Clinical Centre, St James s University Hospital, Leeds, UK
    Cancer 112:971-81. 2008
  7. ncbi request reprint Should the Gleason grading system for prostate cancer be modified to account for high-grade tertiary components? A systematic review and meta-analysis
    Patricia Harnden
    Cancer Research UK Clinical Centre, St James s University Hospital, Leeds, UK
    Lancet Oncol 8:411-9. 2007
  8. ncbi request reprint Cytokeratin expression patterns in normal and malignant urothelium: a review of the biological and diagnostic implications
    J Southgate
    ICRF Cancer Medicine Research Unit, Research School of Medicine, St James s University Hospital, Leeds, UK
    Histol Histopathol 14:657-64. 1999
  9. ncbi request reprint APE1 and XRCC1 protein expression levels predict cancer-specific survival following radical radiotherapy in bladder cancer
    Sei C Sak
    Cancer Research UK Clinical Centre, St James s University Hospital, Leeds, United Kingdom
    Clin Cancer Res 11:6205-11. 2005
  10. ncbi request reprint Uroplakin gene expression in normal human tissues and locally advanced bladder cancer
    Jonathon Olsburgh
    Imperial Cancer Research Fund Clinical Centre, Leeds, UK
    J Pathol 199:41-9. 2003

Collaborators

  • Jennifer Southgate
  • Margaret A Knowles
  • Malcolm Mason
  • J Melia
  • Mike D Shelley
  • Sue M Moss
  • Johanne Bentley
  • Anne E Kiltie
  • Sei C Sak
  • Ananya Choudhury
  • Claire F Taylor
  • Johanna Lowery
  • Fiona M Platt
  • Carolyn D Hurst
  • Colin F Johnston
  • Nicholas P Munro
  • Rosamonde E Banks
  • Barbara Smith
  • Jonathon Olsburgh
  • Christine P Diggle
  • Faye Elliott
  • Robert G Bristow
  • Sameer Chilka
  • Michael Churchman
  • Selina Bhattarai
  • Louisa D Nelson
  • Mark T W Teo
  • D Timothy Bishop
  • Corine L'Hôte
  • Fiona Platt
  • Walter M Gregory
  • Claire Taylor
  • David A Cairns
  • Douglas Thompson
  • Mark Rogers
  • Jennifer H Barrett
  • Anthea J Stanley
  • Paul Clarke
  • Ian Eardley
  • Alan B Paul
  • Peter Selby
  • Peter J Selby
  • Geoffrey Hall
  • Robert Weeks
  • Richard Poulsom
  • Sheena Cruickshank
  • Stephanie Pellegrin
  • Jonathon D Olsburgh
  • Adrian Joyce

Detail Information

Publications15

  1. doi request reprint Evaluation of the use of digital images for a national prostate core external quality assurance scheme
    Patricia Harnden
    Histopathology, Leeds Teaching Hospitals NHS Trust, St James s University Hospital, Leeds, UK
    Histopathology 59:703-9. 2011
    ..To evaluate the use of virtual images as an alternative to glass slides to expand the number of participants in the External Quality Assurance Scheme for prostatic biopsies...
  2. doi request reprint Does the extent of carcinoma in prostatic biopsies predict prostate-specific antigen recurrence? A systematic review
    Patricia Harnden
    Cancer Research UK Clinical Centre, St James s University Hospital, Beckett Street, Leeds, United Kingdom
    Eur Urol 54:728-39. 2008
    ..The biologic potential of prostate cancer (pCA) is variable, and the ability to identify tumours that might cause morbidity and mortality is limited...
  3. doi request reprint Prostatic pathology reporting in the UK: development of a national external quality assurance scheme
    P Harnden
    Cancer Research UK Clinical Centre, St James s University Hospital, Leeds, UK
    Histopathology 52:147-57. 2008
    ....
  4. ncbi request reprint The prognostic significance of perineural invasion in prostatic cancer biopsies: a systematic review
    Patricia Harnden
    Cancer Research UK Clinical Centre, St James s University Hospital, Leeds, United Kingdom
    Cancer 109:13-24. 2007
    ..However, the data are limited, and well-designed studies that use predefined stringent protocols are required to provide robust estimates of risk to aid in treatment planning...
  5. ncbi request reprint A critical appraisal of the classification of urothelial tumours: time for a review of the evidence and a radical change?
    Patricia Harnden
    Leeds Teaching Hospitals NHS Trust, St James s University Hospital, Leeds, UK
    BJU Int 99:723-5. 2007
  6. doi request reprint The clinical management of patients with a small volume of prostatic cancer on biopsy: what are the risks of progression? A systematic review and meta-analysis
    Patricia Harnden
    Cancer Research United Kingdom Clinical Centre, St James s University Hospital, Leeds, UK
    Cancer 112:971-81. 2008
    ..The authors concluded that patients with microfocal carcinoma on biopsy should be advised that their disease is not necessarily "insignificant" and should be counseled accordingly...
  7. ncbi request reprint Should the Gleason grading system for prostate cancer be modified to account for high-grade tertiary components? A systematic review and meta-analysis
    Patricia Harnden
    Cancer Research UK Clinical Centre, St James s University Hospital, Leeds, UK
    Lancet Oncol 8:411-9. 2007
    ..Therefore, more evidence is needed to warrant the adaptation of the Gleason system to account for the presence of a tertiary grade, especially when scoring prostatic biopsies and applying predictive algorithms...
  8. ncbi request reprint Cytokeratin expression patterns in normal and malignant urothelium: a review of the biological and diagnostic implications
    J Southgate
    ICRF Cancer Medicine Research Unit, Research School of Medicine, St James s University Hospital, Leeds, UK
    Histol Histopathol 14:657-64. 1999
    ..This review will consider cytokeratin expression in urothelium and discuss the application of cytokeratin typing to the diagnosis and prognosis of patients with TCC...
  9. ncbi request reprint APE1 and XRCC1 protein expression levels predict cancer-specific survival following radical radiotherapy in bladder cancer
    Sei C Sak
    Cancer Research UK Clinical Centre, St James s University Hospital, Leeds, United Kingdom
    Clin Cancer Res 11:6205-11. 2005
    ..We therefore investigated the prognostic value of the DNA repair proteins APE1 and XRCC1 in patients with muscle-invasive bladder cancer treated by radical radiotherapy...
  10. ncbi request reprint Uroplakin gene expression in normal human tissues and locally advanced bladder cancer
    Jonathon Olsburgh
    Imperial Cancer Research Fund Clinical Centre, Leeds, UK
    J Pathol 199:41-9. 2003
    ....
  11. ncbi request reprint Urinary biomarker profiling in transitional cell carcinoma
    Nicholas P Munro
    Cancer Research UK Clinical Centre, St James s University Hospital, Beckett Street, Leeds, United Kingdom
    Int J Cancer 119:2642-50. 2006
    ..Identification of the relevant peaks may facilitate multiplex marker assay development for detection of recurrent disease...
  12. pmc Identification of genes up-regulated in urothelial tumors: the 67-kd laminin receptor and tumor-associated trypsin inhibitor
    Christine P Diggle
    Cancer Research United Kingdom Clinical Centre, St James s University Hospital, Leeds, UK
    Am J Pathol 163:493-504. 2003
    ....
  13. doi request reprint Papillary and muscle invasive bladder tumors with distinct genomic stability profiles have different DNA repair fidelity and KU DNA-binding activities
    Johanne Bentley
    Cancer Research UK Clinical Centre, Section of Experimental Oncology, Leeds Institute of Molecular Medicine, St James s University Hospital, Leeds, UK
    Genes Chromosomes Cancer 48:310-21. 2009
    ..End-joining fidelity correlated with stage and was increasingly error-prone as tumors became more invasive and KU binding activity reduced; these changes may underlie the different genomic profiles of these tumors...
  14. doi request reprint Spectrum of phosphatidylinositol 3-kinase pathway gene alterations in bladder cancer
    Fiona M Platt
    Cancer Research UK Clinical Centre, Leeds Institute of Molecular Medicine, United Kingdom
    Clin Cancer Res 15:6008-17. 2009
    ..Our aim was to assess the frequency and distribution of pathway alterations in bladder cancer...
  15. pmc MRE11 expression is predictive of cause-specific survival following radical radiotherapy for muscle-invasive bladder cancer
    Ananya Choudhury
    Sections of Experimental Oncology and Epidemiology and Biostatistics, Leeds Institute of Molecular Medicine, Cancer Research UK Genome Variation Laboratory Service, Leeds, United Kingdom
    Cancer Res 70:7017-26. 2010
    ..MRE11 expression may ultimately allow patient selection for radiotherapy or cystectomy, thus improving overall cure rates...