Naveed Sattar

Summary

Country: UK

Publications

  1. pmc First-trimester prediction of gestational diabetes mellitus: examining the potential of combining maternal characteristics and laboratory measures
    Makrina Savvidou
    Department of Maternal Fetal Medicine, Imperial College School of Medicine, Chelsea and Westminster Hospital, London, UK
    Diabetes 59:3017-22. 2010
  2. doi request reprint Lipid-lowering efficacy of the PCSK9 inhibitor evolocumab (AMG 145) in patients with type 2 diabetes: a meta-analysis of individual patient data
    Naveed Sattar
    Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK Electronic address
    Lancet Diabetes Endocrinol 4:403-10. 2016
  3. pmc SGLT2 Inhibition and cardiovascular events: why did EMPA-REG Outcomes surprise and what were the likely mechanisms?
    Naveed Sattar
    BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, 126 University Avenue, Glasgow, G12 8TA, UK
    Diabetologia 59:1333-9. 2016
  4. doi request reprint Type 2 diabetes in migrant south Asians: mechanisms, mitigation, and management
    Naveed Sattar
    Institute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK Electronic address
    Lancet Diabetes Endocrinol 3:1004-16. 2015
  5. pmc The emergence of proton nuclear magnetic resonance metabolomics in the cardiovascular arena as viewed from a clinical perspective
    Naomi J Rankin
    BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, G12 8TA, UK Glasgow Polyomics, Joseph Black Building, University of Glasgow, Glasgow, G12 8QQ, UK Electronic address
    Atherosclerosis 237:287-300. 2014
  6. pmc A dysglycaemic effect of statins in diabetes: relevance to clinical practice?
    Daniel I Swerdlow
    Institute of Cardiovascular Science, University College London, 222 Euston Road, London, NW1 2DA, UK
    Diabetologia 57:2433-5. 2014
  7. pmc A complex intervention to improve pregnancy outcome in obese women; the UPBEAT randomised controlled trial
    Annette L Briley
    Division of Women s Health, Women s Health Academic Centre, King s College London and King s Health Partners, 10th Floor, North Wing, St, Thomas Hospital, London SE1 7EH, UK
    BMC Pregnancy Childbirth 14:74. 2014
  8. pmc Type 2 diabetes as a disease of ectopic fat?
    Naveed Sattar
    Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK
    BMC Med 12:123. 2014
  9. pmc Revisiting the J shaped curve, exploring the association between cardiovascular risk factors and concurrent depressive symptoms in patients with cardiometabolic disease: Findings from a large cross-sectional study
    Bhautesh Dinesh Jani
    Professor of Primary Care Research, General Practice and Primary Care, Institute of Health and Wellbeing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G112 9LX, UK
    BMC Cardiovasc Disord 14:139. 2014
  10. pmc First-trimester circulating 25-hydroxyvitamin D levels and development of gestational diabetes mellitus
    Mahlatse Makgoba
    Department of Maternal Fetal Medicine, Imperial College School of Medicine, Chelsea and Westminster Hospital, London, UK
    Diabetes Care 34:1091-3. 2011

Detail Information

Publications115 found, 100 shown here

  1. pmc First-trimester prediction of gestational diabetes mellitus: examining the potential of combining maternal characteristics and laboratory measures
    Makrina Savvidou
    Department of Maternal Fetal Medicine, Imperial College School of Medicine, Chelsea and Westminster Hospital, London, UK
    Diabetes 59:3017-22. 2010
    ..Our objective was to integrate several potential GDM predictors with consideration to both simple and novel measures and to determine the extent to which GDM can be predicted in the first trimester...
  2. doi request reprint Lipid-lowering efficacy of the PCSK9 inhibitor evolocumab (AMG 145) in patients with type 2 diabetes: a meta-analysis of individual patient data
    Naveed Sattar
    Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK Electronic address
    Lancet Diabetes Endocrinol 4:403-10. 2016
    ..We compared the effect of the PCSK9 inhibitor evolocumab on lipid parameters in patients with and without type 2 diabetes...
  3. pmc SGLT2 Inhibition and cardiovascular events: why did EMPA-REG Outcomes surprise and what were the likely mechanisms?
    Naveed Sattar
    BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, 126 University Avenue, Glasgow, G12 8TA, UK
    Diabetologia 59:1333-9. 2016
    ..Finally, areas for future research are suggested to better understand the relevant mechanisms and to identify other groups who may benefit from SGLT2 inhibitor therapy. ..
  4. doi request reprint Type 2 diabetes in migrant south Asians: mechanisms, mitigation, and management
    Naveed Sattar
    Institute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK Electronic address
    Lancet Diabetes Endocrinol 3:1004-16. 2015
    ..We review these aspects and suggest areas for future research...
  5. pmc The emergence of proton nuclear magnetic resonance metabolomics in the cardiovascular arena as viewed from a clinical perspective
    Naomi J Rankin
    BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, G12 8TA, UK Glasgow Polyomics, Joseph Black Building, University of Glasgow, Glasgow, G12 8QQ, UK Electronic address
    Atherosclerosis 237:287-300. 2014
    ....
  6. pmc A dysglycaemic effect of statins in diabetes: relevance to clinical practice?
    Daniel I Swerdlow
    Institute of Cardiovascular Science, University College London, 222 Euston Road, London, NW1 2DA, UK
    Diabetologia 57:2433-5. 2014
    ..Finally, we remind colleagues that nearly all drugs have side effects and we should not be surprised by this statin-dysglycaemia effect, which can be easily managed...
  7. pmc A complex intervention to improve pregnancy outcome in obese women; the UPBEAT randomised controlled trial
    Annette L Briley
    Division of Women s Health, Women s Health Academic Centre, King s College London and King s Health Partners, 10th Floor, North Wing, St, Thomas Hospital, London SE1 7EH, UK
    BMC Pregnancy Childbirth 14:74. 2014
    ..A secondary aim is to determine whether the intervention lowers the long term risk of obesity in the offspring...
  8. pmc Type 2 diabetes as a disease of ectopic fat?
    Naveed Sattar
    Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK
    BMC Med 12:123. 2014
    ..Although obesity and diabetes commonly co-exist, the evidence base to support obesity as the major driver of type 2 diabetes mellitus (T2DM), and the mechanisms by which this occurs, are now better appreciated...
  9. pmc Revisiting the J shaped curve, exploring the association between cardiovascular risk factors and concurrent depressive symptoms in patients with cardiometabolic disease: Findings from a large cross-sectional study
    Bhautesh Dinesh Jani
    Professor of Primary Care Research, General Practice and Primary Care, Institute of Health and Wellbeing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G112 9LX, UK
    BMC Cardiovasc Disord 14:139. 2014
    ..The objective of this paper is to study the association between cardiovascular risk factors and concurrent depressive symptoms in patients with three common cardiometabolic conditions: coronary heart disease (CHD), stroke and diabetes...
  10. pmc First-trimester circulating 25-hydroxyvitamin D levels and development of gestational diabetes mellitus
    Mahlatse Makgoba
    Department of Maternal Fetal Medicine, Imperial College School of Medicine, Chelsea and Westminster Hospital, London, UK
    Diabetes Care 34:1091-3. 2011
    ..To investigate the association between first-trimester maternal serum levels of 25-hydroxyvitamin D (25-OH-D) as measured by liquid chromatography-tandem mass spectrometry and development of gestational diabetes mellitus (GDM)...
  11. doi request reprint The use of statins in people at risk of developing diabetes mellitus: evidence and guidance for clinical practice
    Naveed A Sattar
    Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK Electronic address
    Atheroscler Suppl 15:1-15. 2014
    ..Should a patient develop T2D during statin treatment, physicians should continue with statin therapy and manage T2D in accordance with relevant national guidelines. ..
  12. doi request reprint Gender aspects in type 2 diabetes mellitus and cardiometabolic risk
    Naveed Sattar
    Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK Electronic address
    Best Pract Res Clin Endocrinol Metab 27:501-7. 2013
    ..This chapter explores the relevant data underlying this observation, examines potential mechanisms including life course changes in insulin resistance and role of adiposity, and discusses relevant clinical implications and solutions. ..
  13. doi request reprint Revisiting the links between glycaemia, diabetes and cardiovascular disease
    N Sattar
    Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK
    Diabetologia 56:686-95. 2013
    ....
  14. doi request reprint Statins are diabetogenic--myth or reality?
    Naveed Sattar
    Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK
    Atheroscler Suppl 13:1-10. 2012
    ..Nevertheless, the level of evidence has been sufficient to lead the FDA to make a change to the labelling of statins. This review assesses the current available evidence and offers a clinical perspective...
  15. doi request reprint HbA1c in type 2 diabetes diagnostic criteria: addressing the right questions to move the field forwards
    N Sattar
    BHF Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK
    Diabetologia 55:1564-7. 2012
    ..Instead, we provide a list of important future questions, including whether adoption of HbA(1c) as the primary diagnostic test improves uptake of diabetes screening, with resultant earlier diagnosis and improvement in outcomes...
  16. pmc Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses
    Stella Trompet
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    BMC Med Genet 12:131. 2011
    ..In this report we first describe the rationale of the PROSPER/PHASE project and second show that the PROSPER/PHASE study can be used to study pharmacogenetics in the elderly...
  17. doi request reprint Biomarkers for diabetes prediction, pathogenesis or pharmacotherapy guidance? Past, present and future possibilities
    N Sattar
    Faculty of Medicine, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK
    Diabet Med 29:5-13. 2012
    ..In summary, biomarker research in diabetes is continuing apace in a number of areas, but it remains to be seen whether the promise of biomarker research to improve the care of our patients becomes a reality...
  18. pmc Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice
    Ashley M Miller
    Division of Immunology, Infection and Inflammation, GBRC, University of Glasgow, Glasgow, United Kingdom
    Circ Res 107:650-8. 2010
    ..The cytokine interleukin (IL)-33 and its receptor ST2 are expressed in adipose tissue, but their role in adipose tissue inflammation during obesity is unclear...
  19. pmc Leptin predicts diabetes but not cardiovascular disease: results from a large prospective study in an elderly population
    Paul Welsh
    Faculty of Medicine, University of Glasgow, Scotland, UK
    Diabetes Care 32:308-10. 2009
    ..To clarify the association of circulating levels of leptin with risk for cardiovascular disease (CVD) events and new-onset diabetes in men and women...
  20. doi request reprint Vascular dysfunction and alteration of novel and classic cardiovascular risk factors in mothers of growth restricted offspring
    Malini G Kanagalingam
    Reproductive and Maternal Medicine, University of Glasgow, Glasgow, United Kingdom
    Atherosclerosis 205:244-50. 2009
    ..However, whether established or putative novel cardiovascular risk factors including vascular and metabolic function are disrupted in women who delivered small for gestational age (SGA) offspring is unknown...
  21. ncbi request reprint Effects of low-dose continuous combined HRT on vascular function in women with type 2 diabetes
    Andrew F B Kernohan
    Division of Cardiovascular and Medical Sciences, University of Glasgow, 36 Church St, Glasgow, G11 6NT, UK
    Diab Vasc Dis Res 1:82-8. 2004
    ..Women with type 2 diabetes (T2DM) are at increased cardiovascular risk and have impaired endothelial function. Any benefits of HRT on endothelial function in this group are of particular interest...
  22. pmc Programming of adiposity in offspring of mothers with type 1 diabetes at age 7 years
    Robert S Lindsay
    Faculty of Medicine, University of Glasgow, Glasgow, UK
    Diabetes Care 33:1080-5. 2010
    ....
  23. doi request reprint Adipocytokines and risk of stroke in older people: a nested case-control study
    David J Stott
    Division of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Scotland, UK
    Int J Epidemiol 38:253-61. 2009
    ..Inflammation may play an important role in atherothrombosis and in promoting cerebral damage after stroke. We hypothesized that plasma adipocytokine concentrations would be associated with risk of stroke in older people...
  24. doi request reprint Socioeconomic deprivation and cortical morphology: psychological, social, and biological determinants of ill health study
    Rajeev Krishnadas
    Sackler Institute of Psychobiological Research, Southern General Hospital, Glasgow, Scotland, UK
    Psychosom Med 75:616-23. 2013
    ..The aim of this study was to examine the association between neighborhood-level deprivation and the morphology of cortical regions associated with language and executive control in adults...
  25. pmc N-terminal pro-B-type natriuretic peptide and the prediction of primary cardiovascular events: results from 15-year follow-up of WOSCOPS
    Paul Welsh
    College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK
    Eur Heart J 34:443-50. 2013
    ..To test whether N-terminal pro-B-type natriuretic peptide (NT-proBNP) was independently associated with, and improved the prediction of, cardiovascular disease (CVD) in a primary prevention cohort...
  26. ncbi request reprint Inflammation and endothelial activation is evident at birth in offspring of mothers with type 1 diabetes
    Scott M Nelson
    Division of Developmental Medicine, University of Glasgow, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow, G31 2ER, UK
    Diabetes 56:2697-704. 2007
    ..We examined whether these biomarkers were elevated at birth in offspring of type 1 diabetic mothers (OT1DM)...
  27. doi request reprint The inverse relationship between alanine aminotransferase in the normal range and adverse cardiovascular and non-cardiovascular outcomes
    Ian Ford
    From the Robertson Centre for Biostatistics, University of Glasgow, Glasgow, Scotland
    Int J Epidemiol 40:1530-8. 2011
    ..High serum alanine aminotransferase (ALT) levels have been associated with increased risk of diabetes and with increased mortality, but associations of variations of ALT in the normal range with outcomes have been less well studied...
  28. ncbi request reprint Serial metabolic measurements and conversion to type 2 diabetes in the west of Scotland coronary prevention study: specific elevations in alanine aminotransferase and triglycerides suggest hepatic fat accumulation as a potential contributing factor
    Naveed Sattar
    Department of Vascular Biochemistry, University of Glasgow, Glasgow, Scotland
    Diabetes 56:984-91. 2007
    ....
  29. doi request reprint Socioeconomic status and the cerebellar grey matter volume. Data from a well-characterised population sample
    Jonathan Cavanagh
    Sackler Institute of Psychobiological Research, Institute of Health and Wellbeing, University of Glasgow, Glasgow, Scotland, UK
    Cerebellum 12:882-91. 2013
    ..These findings provide data on the relationship between socioeconomic deprivation and a brain region highly sensitive to environmental factors. ..
  30. pmc Reduced glomerular filtration rate and its association with clinical outcome in older patients at risk of vascular events: secondary analysis
    Ian Ford
    Robertson Centre for Biostatistics, University of Glasgow, Glasgow, Scotland
    PLoS Med 6:e16. 2009
    ..We aimed to determine the predictive value of the GFR for mortality and morbidity using data from the 5,804 participants randomized in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)...
  31. doi request reprint Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies
    Naveed Sattar
    Faculty of Medicine, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK
    Lancet 371:1927-35. 2008
    ..We investigated to what extent metabolic syndrome and its individual components were related to risk for these two diseases in elderly populations...
  32. doi request reprint Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials
    Naveed Sattar
    British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK
    Lancet 375:735-42. 2010
    ..We aimed to establish by a meta-analysis of published and unpublished data whether any relation exists between statin use and development of diabetes...
  33. pmc Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events?
    Naveed Sattar
    Division of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, Scotland, UK
    PLoS Med 6:e1000099. 2009
    ..We tested whether interleukin (IL)-6, C-reactive protein (CRP), and fibrinogen more strongly associate with fatal compared to nonfatal myocardial infarction (MI) and stroke...
  34. doi request reprint High adiponectin and increased risk of cardiovascular disease and mortality in asymptomatic older men: does NT-proBNP help to explain this association?
    Sasiwarang Goya Wannamethee
    Department of Primary Care and Population Health, UCL, London, UK
    Eur J Cardiovasc Prev Rehabil 18:65-71. 2011
    ..We examined whether N-terminal pro-brain natriuretic peptide (NT-proBNP), a marker of cardiac dysfunction, may help explain this relationship...
  35. ncbi request reprint Effects of a moderate exercise session on postprandial lipoproteins, apolipoproteins and lipoprotein remnants in middle-aged men
    Jason M R Gill
    Department of Vascular Biochemistry, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK
    Atherosclerosis 185:87-96. 2006
    ....
  36. pmc Do the pleiotropic effects of statins in the vasculature predict a role in inflammatory diseases?
    David W McCarey
    Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK
    Arthritis Res Ther 7:55-61. 2005
    ..Together with their known vasculoprotective effects, this growing body of evidence provides compelling support for longer-term trials of statin therapy in human disease such as rheumatoid arthritis...
  37. ncbi request reprint Effects of HRT on liver enzyme levels in women with type 2 diabetes: a randomized placebo-controlled trial
    Joyce McKenzie
    Department of Medicine, Glasgow Royal Infirmary University NHS Trust, Glasgow, Scotland, UK
    Clin Endocrinol (Oxf) 65:40-4. 2006
    ..g. nonalcoholic fatty liver disease (NAFLD)]. Recent data indicating that hormone replacement therapy (HRT) may lessen diabetes risk is intriguing but explanatory mechanisms are unclear...
  38. doi request reprint The incidence and risk factors for new onset atrial fibrillation in the PROSPER study
    Peter W Macfarlane
    Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK
    Europace 13:634-9. 2011
    ..We aimed to determine retrospectively whether pravastatin reduces the incidence of AF and whether any electrocardiographic measures or clinical conditions might be risk factors for its development...
  39. pmc Personality, socio-economic status and inflammation: cross-sectional, population-based study
    Keith Millar
    College of Medical, Veterinary and Life Sciences, Institute of Mental Health and Wellbeing, University of Glasgow, Glasgow, Scotland
    PLoS ONE 8:e58256. 2013
    ....
  40. doi request reprint Obesity is associated with fatal coronary heart disease independently of traditional risk factors and deprivation
    Jennifer Logue
    BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK
    Heart 97:564-8. 2011
    ..However, there is now evidence of a differential effect of risk factors on fatal and non-fatal CHD events, with markers of inflammation more strongly associated with fatal than non-fatal events...
  41. pmc Prediction of Cardiovascular Disease Risk by Cardiac Biomarkers in 2 United Kingdom Cohort Studies: Does Utility Depend on Risk Thresholds For Treatment?
    Paul Welsh
    From the Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre P W, D P, N S, Institute of Health and Wellbeing C H, G W, and Robertson Centre for Biostatistics A M, H M, University of Glasgow, Glasgow, United Kingdom Department of Primary Care and Population Health, University College London, London, United Kingdom O P, S R, P W, G W and Helmsley Medical Centre, Helmsley, York, United Kingdom M U
    Hypertension 67:309-15. 2016
    ..0%-9.2% and 2.6%; 0.0%-5.8%, respectively). In conclusion, the improvement in treatment allocation gained by adding cardiac biomarkers to risk scores seems to depend on the risk threshold chosen for commencing preventative treatments. ..
  42. doi request reprint Effects of a beverage rich in (poly)phenols on established and novel risk markers for vascular disease in medically uncomplicated overweight or obese subjects: A four week randomized placebo-controlled trial
    Adam Mullan
    Institute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow, Cardiovascular Research Centre, University of Glasgow, UK
    Atherosclerosis 246:169-76. 2016
    ....
  43. doi request reprint Apolipoprotein E-deficient mice are resistant to the development of collagen-induced arthritis
    Darren L Asquith
    University of Glasgow, Glasgow, UK
    Arthritis Rheum 62:472-7. 2010
    ..To determine whether elevated serum lipid levels resulting from feeding animals a high-fat diet can affect the inflammatory process in C57BL/6 (B6) wild-type (WT) and B6 ApoE(-/-) mouse models of collagen-induced arthritis (CIA)...
  44. pmc Ethnicity and prediction of cardiovascular disease: performance of QRISK2 and Framingham scores in a U.K. tri-ethnic prospective cohort study (SABRE--Southall And Brent REvisited)
    Therese Tillin
    International Centre for Circulatory Health, National Heart and Lung Institute, Imperial College London, London, UK
    Heart 100:60-7. 2014
    ..To evaluate QRISK2 and Framingham cardiovascular disease (CVD) risk scores in a tri-ethnic U.K. population...
  45. ncbi request reprint Short- and long-term changes in plasma inflammatory markers associated with preeclampsia
    Dilys J Freeman
    Division of Developmental Medicine, University of Glasgow, Glasgow, United Kingdom
    Hypertension 44:708-14. 2004
    ..In conclusion, preeclampsia is associated with short- and long-term changes in inflammatory status...
  46. doi request reprint Allopurinol use yields potentially beneficial effects on inflammatory indices in those with recent ischemic stroke: a randomized, double-blind, placebo-controlled trial
    Scott W Muir
    Division of Cardiovascular and Medical Sciences, Acute Stroke Unit, University of Glasgow, Western Infirmary, Glasgow, UK
    Stroke 39:3303-7. 2008
    ..We sought to investigate whether allopurinol alters expression of inflammatory markers after acute ischemic stroke...
  47. pmc Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes?
    Ashley M Miller
    Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
    PLoS ONE 7:e47830. 2012
    ..Further mechanistic studies determining how sST2 is linked to diabetes pathways may offer new insights into the inflammatory paradigm for type 2 diabetes...
  48. doi request reprint Role of adiponectin in matching of fetal and placental weight in mothers with type 1 diabetes
    Scott M Nelson
    Faculty of Medicine, University of Glasgow, Glasgow, UK
    Diabetes Care 31:1123-5. 2008
    ..To assess the association of fetal hormones with placental growth and fetal weight-to-placental weight ratio index (FPI) in pregnancies complicated by maternal diabetes...
  49. pmc Fasting plasma glucose in non-diabetic participants and the risk for incident cardiovascular events, diabetes, and mortality: results from WOSCOPS 15-year follow-up
    David Preiss
    Faculty of Medicine, University of Glasgow, Glasgow, UK
    Eur Heart J 31:1230-6. 2010
    ..The evidence base for fasting plasma glucose (FPG) in the non-diabetic range as a risk factor for cardiovascular disease (CVD) is inconclusive. We investigated this question in the West of Scotland Coronary Prevention Study (WOSCOPS)...
  50. doi request reprint Role for TNF in atherosclerosis? Lessons from autoimmune disease
    Gayle E McKellar
    Center for Rheumatic Diseases, Glasgow, Royal Infirmary, Glasgow, UK
    Nat Rev Cardiol 6:410-7. 2009
    ..Moreover, such data obtained in chronic inflammatory diseases likely have relevance to primary atherosclerosis...
  51. ncbi request reprint Metabolic, inflammatory and haemostatic effects of a low-dose continuous combined HRT in women with type 2 diabetes: potentially safer with respect to vascular risk?
    Joyce McKenzie
    Diabetes Centre, Glasgow Royal Infirmary University NHS Trust, Glasgow, UK
    Clin Endocrinol (Oxf) 59:682-9. 2003
    ....
  52. doi request reprint Leptin and coronary heart disease: prospective study and systematic review
    Naveed Sattar
    BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, University of Glasgow, Glasgow, Scotland, UK
    J Am Coll Cardiol 53:167-75. 2009
    ..This study sought to better determine the link between leptin and coronary heart disease (CHD)...
  53. pmc Fat oxidation, fitness and skeletal muscle expression of oxidative/lipid metabolism genes in South Asians: implications for insulin resistance?
    Lesley M L Hall
    Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom
    PLoS ONE 5:e14197. 2010
    ..We investigated whether differences in oxidative capacity and capacity for fatty acid utilisation in South Asians might contribute, using a range of whole-body and skeletal muscle measures...
  54. pmc Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort
    Paul G Shiels
    Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland
    PLoS ONE 6:e22521. 2011
    ....
  55. pmc Temporal Evolution of Myocardial Hemorrhage and Edema in Patients After Acute ST-Segment Elevation Myocardial Infarction: Pathophysiological Insights and Clinical Implications
    David Carrick
    BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK Robertson Center for Biostatistics, University of Glasgow, UK
    J Am Heart Assoc 5:. 2016
    ..The time course and relationships of myocardial hemorrhage and edema in patients after acute ST-segment elevation myocardial infarction (STEMI) are uncertain...
  56. pmc Corrigendum to "Cardio-metabolic risk factors and cortical thickness in a neurologically healthy male population: Results from the psychological, social and biological determinants of ill health (pSoBid) study" [Neuroimage Clin. 2 (2013) 646-57]
    Rajeev Krishnadas
    Sackler Institute of Psychobiological Research, Institute of Health and Wellbeing, University of Glasgow, Glasgow, Scotland, UK
    Neuroimage Clin 9:e1. 2015
    ..This corrects the article DOI: 10.1016/j.nicl.2013.04.012.]. ..
  57. ncbi request reprint Vitamin antioxidants, lipid peroxidation and the systemic inflammatory response in patients with prostate cancer
    Ahmed S K Almushatat
    University Department of Surgery, Royal Infirmary, Glasgow, UK
    Int J Cancer 118:1051-3. 2006
    ..269, p = 0.017). These results indicate that lower concentrations of carotenoids, in particular, lycopene reflect disease progression rather than the systemic inflammatory response in patients with prostate cancer...
  58. ncbi request reprint Serum C-reactive protein and lipids in ultra-Marathon runners
    Maciej Tomaszewski
    British Heart Foundation Glasgow Cardiovascular Research Centre, Division of Cardiovascular and Medical Sciences, and Department of Pathological Biochemistry, University of Glasgow, Glasgow, United Kingdom
    Am J Cardiol 94:125-6. 2004
    ..This exercise-induced reduction in low-density lipoprotein cholesterol was independent of the decrease in C-reactive protein levels...
  59. doi request reprint Liver X receptor agonism promotes articular inflammation in murine collagen-induced arthritis
    Darren L Asquith
    Glasgow Biomedical Research Center, Division of Infection, Immunity and Inflammation, University of Glasgow, 120 University Place, Glasgow, UK
    Arthritis Rheum 60:2655-65. 2009
    ..This study was therefore undertaken to explore the biologic mechanisms of LXRs in vivo and in vitro in an experimental inflammatory arthritis model...
  60. doi request reprint NT-proBNP is associated with coronary heart disease risk in healthy older women but fails to enhance prediction beyond established risk factors: results from the British Women's Heart and Health Study
    Naveed Sattar
    Division of Cardiovascular and Medical Sciences, BHF Cardiovascular Research Building, Faculty of Medicine, University of Glasgow, 126 University Place, Scotland, UK
    Atherosclerosis 209:295-9. 2010
    ..Limited evidence suggests NT-proBNP improves prediction of coronary heart disease (CHD) events but further data are needed, especially in people without pre-existing CHD and in women...
  61. doi request reprint Intergenerational change and familial aggregation of body mass index
    Paul C D Johnson
    Robertson Centre for Biostatistics, Boyd Orr Building, University of Glasgow, Glasgow, UK
    Eur J Epidemiol 27:53-61. 2012
    ..Familial influences on BMI among middle-aged women appear significantly stronger from mothers than fathers...
  62. pmc Prognostic significance of infarct core pathology revealed by quantitative non-contrast in comparison with contrast cardiac magnetic resonance imaging in reperfused ST-elevation myocardial infarction survivors
    David Carrick
    BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G128TA, UK West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK
    Eur Heart J 37:1044-59. 2016
    ..To assess the prognostic significance of infarct core tissue characteristics using cardiac magnetic resonance (CMR) imaging in survivors of acute ST-elevation myocardial infarction (STEMI)...
  63. doi request reprint The incremental prognostic and clinical value of multiple novel biomarkers in heart failure
    Colette E Jackson
    British Heart Foundation Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow, G12 8TA, UK
    Eur J Heart Fail 18:1491-1498. 2016
    ..In recent years there has been an increase in the number of biomarkers in heart failure (HF). The clinical role for these novel biomarkers in combination is not clear...
  64. pmc Remote Zone Extracellular Volume and Left Ventricular Remodeling in Survivors of ST-Elevation Myocardial Infarction
    Jaclyn Carberry
    From the BHF Glasgow Cardiovascular Research Centre J C, D C, S M R, N A, I M, M M, M C P, H E, S H, S W, M L, A D, A M, N S, P W, A R, K G O, C B and Robertson Centre for Biostatistics C H, I F, University of Glasgow, Glasgow, United Kingdom and Golden Jubilee National Hospital, Dunbartonshire, United Kingdom D C, S W, C B
    Hypertension 68:385-91. 2016
    ..43 (0.10-2.76); P=0.036). ΔECV is implicated in the pathophysiology of left ventricular remodeling post STEMI, but because the effect size is small, ΔECV has limited use as a clinical biomarker of remodeling...
  65. ncbi request reprint Effects of prior moderate exercise on postprandial metabolism and vascular function in lean and centrally obese men
    Jason M R Gill
    Department of Vascular Biochemistry, University of Glasgow, Glasgow Royal Infirmary, Glasgow G12 8QQ, Scotland, UK
    J Am Coll Cardiol 44:2375-82. 2004
    ..We investigated whether a session of prior exercise could ameliorate postprandial endothelial dysfunction...
  66. doi request reprint Contrasting associations of insulin resistance with diabetes, cardiovascular disease and all-cause mortality in the elderly: PROSPER long-term follow-up
    Paul Welsh
    British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, G12 8TA, UK
    Diabetologia 57:2513-20. 2014
    ..We assessed the association of fasting insulin and HOMA-IR with incident CVD and diabetes in older people...
  67. doi request reprint Circulating 25OHD, dietary vitamin D, PTH, and calcium associations with incident cardiovascular disease and mortality: the MIDSPAN Family Study
    Paul Welsh
    Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, United Kingdom
    J Clin Endocrinol Metab 97:4578-87. 2012
    ..Observational studies relating circulating 25-hydroxyvitamin D (25OHD) and dietary vitamin D intake to cardiovascular disease (CVD) have reported conflicting results...
  68. doi request reprint The value of N-terminal pro-B-type natriuretic peptide in determining antihypertensive benefit: observations from the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT)
    Paul Welsh
    BHF Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Pl, Glasgow G12 8TA, United Kingdom or
    Hypertension 63:507-13. 2014
    ..If confirmed, these novel results suggest that NT-proBNP, as well as aiding cardiovascular disease risk assessment, may also help assess the efficacy of specific antihypertensive regimens. Further relevant studies seem warranted. ..
  69. pmc Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension
    Sandosh Padmanabhan
    Institute of Cardiovascular and Medical Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
    PLoS Genet 6:e1001177. 2010
    ..The newly discovered UMOD locus for hypertension has the potential to give new insights into the role of uromodulin in BP regulation and to identify novel drugable targets for reducing cardiovascular risk...
  70. pmc Evaluation of C-reactive protein prior to and on-treatment as a predictor of benefit from atorvastatin: observations from the Anglo-Scandinavian Cardiac Outcomes Trial
    Peter S Sever
    International Centre for Circulatory Health, Imperial College London, 59 North Wharf Road, London, UK
    Eur Heart J 33:486-94. 2012
    ..We tested whether on-statin C-reactive protein is associated with cardiovascular (CV) outcome in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT)...
  71. doi request reprint Changes in lipid levels with inflammation and therapy in RA: a maturing paradigm
    Jamie Robertson
    Institute of Infection, Immunity and Inflammation, University of Glasgow, 120 University Place, Glasgow, UK
    Nat Rev Rheumatol 9:513-23. 2013
    ..Whether alternative lipid or lipoprotein measures (or simple markers of inflammation) could improve stratification of CVD risk in RA beyond the established risk factors requires future investigation. ..
  72. ncbi request reprint Growth hormone replacement reduces C-reactive protein and large-artery stiffness but does not alter endothelial function in patients with adult growth hormone deficiency
    Roland W McCallum
    Division of Cardiovascular and Medical Sciences, University of Glasgow, Western Infirmary, Glasgow G11 6NT, UK
    Clin Endocrinol (Oxf) 62:473-9. 2005
    ..GH replacement may lead to differentially altered production of vasorelaxant agents from the endothelium of large and small arteries. Reduction in vascular inflammation may be associated with reduced vascular risk...
  73. ncbi request reprint Genetic determinants of metabolic syndrome components in the stroke-prone spontaneously hypertensive rat
    Pamela Strahorn
    BHF Glasgow Cardiovascular Research Centre, Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK
    J Hypertens 23:2179-86. 2005
    ..Animal models may facilitate genetic analysis of complex phenotypes by allowing complete control of environmental conditions and the ability to produce designer strains...
  74. ncbi request reprint Effects of tumor necrosis factor blockade on cardiovascular risk factors in psoriatic arthritis: a double-blind, placebo-controlled study
    Naveed Sattar
    University of Glasgow, Glasgow, UK
    Arthritis Rheum 56:831-9. 2007
    ....
  75. ncbi request reprint Reproducibility and repeatability of peripheral microvascular assessment using iontophoresis in conjunction with laser Doppler imaging
    Sachin Jadhav
    Divisions of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, Scotland, UK
    J Cardiovasc Pharmacol 50:343-9. 2007
    ..LDI can be used to assess peripheral vascular response with good repeatability as long as measurements are corrected for skin resistance, which affects drug delivery. This has important implications for the future use of LDI...
  76. pmc Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)
    Dilys J Freeman
    Centre of Population and Health Sciences, University of Glasgow, Glasgow, UK
    BMC Geriatr 11:8. 2011
    ..We aimed to determine the effect of pravastatin on incident VTE in older people; we also studied the impact of clinical and plasma risk variables...
  77. pmc The effect of statin therapy on heart failure events: a collaborative meta-analysis of unpublished data from major randomized trials
    David Preiss
    BHF Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK
    Eur Heart J 36:1536-46. 2015
    ..The effect of statins on risk of heart failure (HF) hospitalization and HF death remains uncertain. We aimed to establish whether statins reduce major HF events...
  78. pmc Predictors of development of diabetes in patients with chronic heart failure in the Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM) program
    David Preiss
    BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland, UK
    Diabetes Care 32:915-20. 2009
    ....
  79. pmc Associations between dietary fiber and inflammation, hepatic function, and risk of type 2 diabetes in older men: potential mechanisms for the benefits of fiber on diabetes risk
    S Goya Wannamethee
    Department of Primary Care and Population Health, University College Medical School, Hampstead Campus, University College London, London, UK
    Diabetes Care 32:1823-5. 2009
    ..To examine the relationship between dietary fiber and the risk of type 2 diabetes in older men and the role of hepatic and inflammatory markers...
  80. ncbi request reprint High sensitivity C-reactive protein and cardiovascular disease: an association built on unstable foundations?
    Naveed Sattar
    Department of Clinical Biochemistry, University of Glasgow, Glasgow Royal Infirmary, Glasgow G31 2ER, UK
    Ann Clin Biochem 43:252-6. 2006
    ..Therefore, the current focus in clinical practice should remain on established risk factors (e.g. smoking, lipids and blood pressure), both to determine coronary heart disease risk and to reduce it...
  81. doi request reprint Does low to moderate alcohol intake protect against cognitive decline in older people?
    David J Stott
    Faculty of Medicine, Academic Section of Geriatric Medicine, University of Glasgow, Glasgow, United Kingdom
    J Am Geriatr Soc 56:2217-24. 2008
    ..To determine whether low to moderate alcohol intake is protective against cognitive decline in older people...
  82. doi request reprint Liver enzymes, nonalcoholic fatty liver disease, and incident cardiovascular disease: a narrative review and clinical perspective of prospective data
    Nazim Ghouri
    BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK
    Hepatology 52:1156-61. 2010
    ..Finally, although some studies have linked imaging-defined and biopsy-confirmed NAFLD with CVD risk, the evidence is inconsistent, with few incident events and/or insufficient potential confounders...
  83. doi request reprint Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein E-deficient mice
    Neil Macritchie
    Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, 120 University Place, Glasgow G12 8TA, United Kingdom
    Arterioscler Thromb Vasc Biol 32:2569-79. 2012
    ..Results from animal models are controversial, with pDCs seen to inhibit or promote lesion development depending on the experimental settings. Here, we investigated the role of pDCs in atherosclerosis in apolipoprotein E-deficient mice...
  84. ncbi request reprint Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial
    David W McCarey
    Centre for Rheumatic Diseases, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK
    Lancet 363:2015-21. 2004
    ..We postulated that statins might reduce inflammatory factors in rheumatoid arthritis and modify surrogates for vascular risk...
  85. ncbi request reprint Comparison of the associations of apolipoprotein B and non-high-density lipoprotein cholesterol with other cardiovascular risk factors in patients with the metabolic syndrome in the Insulin Resistance Atherosclerosis Study
    Naveed Sattar
    Section of Vascular Biochemistry, North Glasgow Hospitals University NHS Trust, Glasgow Royal Infirmary, Glasgow, UK
    Circulation 110:2687-93. 2004
    ..Both apolipoprotein (apo)B and non-HDL cholesterol (NHDLC) have been proposed as an additional indicator to identify patients at higher risk in MetS patients...
  86. ncbi request reprint Effects of metformin on microvascular function and exercise tolerance in women with angina and normal coronary arteries: a randomized, double-blind, placebo-controlled study
    Sachin Jadhav
    Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, Scotland
    J Am Coll Cardiol 48:956-63. 2006
    ..This study sought to determine whether metformin improves vascular function or myocardial ischemia in nondiabetic subjects...
  87. ncbi request reprint C-reactive protein and prediction of coronary heart disease and global vascular events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)
    Naveed Sattar
    Department of Vascular Biochemistry, University of Glasgow, Glasgow, Scotland, UK
    Circulation 115:981-9. 2007
    ..The role of C-reactive protein (CRP) in predicting vascular events and response to statin therapy remains uncertain. Additional large prospective studies are required...
  88. ncbi request reprint IGF-1 and leptin associate with fetal HDL cholesterol at birth: examination in offspring of mothers with type 1 diabetes
    Scott M Nelson
    Department of Reproductive and Maternal Medicine, Division of Developmental Medicine, University of Glasgow, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow, G31 ER, UK
    Diabetes 56:2705-9. 2007
    ..We examined the influence of maternal diabetes on cord lipids at birth and relationship to body composition, cord insulin, leptin, and other hormonal measures...
  89. doi request reprint Novel antecedent plasma biomarkers of cardiovascular disease: improved evaluation methods and comparator benchmarks raise the bar
    Paul Welsh
    Division of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Scotland, UK
    Curr Opin Lipidol 19:563-71. 2008
    ..To assess recent advances in cardiovascular disease biomarkers, focusing on past failings, current promise, and areas for future work...
  90. doi request reprint Lipid-modifying therapies and risk of pancreatitis: a meta-analysis
    David Preiss
    BHF Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Pl, Glasgow G12 8TA, United Kingdom
    JAMA 308:804-11. 2012
    ..Although lipid guidelines recommend fibrate therapy to reduce pancreatitis risk in persons with hypertriglyceridemia, fibrates may lead to the development of gallstones, a risk factor for pancreatitis...
  91. pmc Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring
    Eleanor Jarvie
    Reproductive and Maternal Medicine, Faculty of Medicine, University of Glasgow, Glasgow, U K
    Clin Sci (Lond) 119:123-9. 2010
    ..The combination of excess/altered lipid nutrient supply, suboptimal in utero metabolic environment and alterations in placental gene expression, inflammation and metabolism may also induce obesity in the offspring...
  92. doi request reprint A systematic review of event rates in clinical trials in diabetes mellitus: the importance of quantifying baseline cardiovascular disease history and proteinuria and implications for clinical trial design
    David Preiss
    BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom
    Am Heart J 161:210-219.e1. 2011
    ....
  93. doi request reprint Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-analysis
    David Preiss
    BHF Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Pl, Glasgow G12 8TA, Scotland, United Kingdom
    JAMA 305:2556-64. 2011
    ..A recent meta-analysis demonstrated that statin therapy is associated with excess risk of developing diabetes mellitus...
  94. doi request reprint Lipids, lipid modifying agents and cardiovascular risk: a review of the evidence
    David Preiss
    BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK
    Clin Endocrinol (Oxf) 70:815-28. 2009
    ..Ongoing studies such as ACCORD, IMPROVE-IT, ASCEND, ORIGIN and HPS2-THRIVE should assist in answering outstanding questions over the next 5 years...
  95. doi request reprint Simultaneous activation of the liver X receptors (LXRα and LXRβ) drives murine collagen-induced arthritis disease pathology
    Darren L Asquith
    Glasgow Biomedical Research Centre, Institute of Immunity, Infection and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, UK
    Ann Rheum Dis 70:2225-8. 2011
    ..It has previously been shown that dual activation of the Liver X Receptors (LXRα and LXRβ) by the agonist, GW3965, enhances pathology in a murine model of collagen-induced arthritis...
  96. doi request reprint Eplerenone and new-onset diabetes in patients with mild heart failure: results from the Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure (EMPHASIS-HF)
    David Preiss
    British Heart Foundation Cardiovascular Research Centre, University of Glasgow, Glasgow G12 8TA, UK
    Eur J Heart Fail 14:909-15. 2012
    ..In addition, though the combination of diabetes and chronic heart failure (CHF) carries a poor prognosis, few studies have examined predictors of new-onset diabetes in those with CHF...
  97. doi request reprint High molecular weight adiponectin is not associated with incident coronary heart disease in older women: a nested prospective case-control study
    Naveed Sattar
    British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom
    J Clin Endocrinol Metab 93:1846-9. 2008
    ..Adiponectin levels appear weakly linked to incident vascular disease, but the high molecular weight (HMW) fraction may be more relevant...
  98. pmc Sitting time and waist circumference are associated with glycemia in U.K. South Asians: data from 1,228 adults screened for the PODOSA trial
    Jason M R Gill
    Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK
    Diabetes Care 34:1214-8. 2011
    ..To investigate the independent contributions of waist circumference, physical activity, and sedentary behavior on glycemia in South Asians living in Scotland...
  99. ncbi request reprint Vascular comorbidity in rheumatoid arthritis: potential mechanisms and solutions
    Naveed Sattar
    Section of Vascular Biochemistry, Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow Royal Infirmary, Scotland, UK
    Curr Opin Rheumatol 17:286-92. 2005
    ..To summarise recent evidence for elevated risk of coronary heart disease (CHD) in rheumatoid arthritis (RA) and explore explanatory mechanisms and modalities that may lessen such risk...
  100. ncbi request reprint Human placental peroxisome proliferator-activated receptor delta and gamma expression in healthy pregnancy and in preeclampsia and intrauterine growth restriction
    Vanessa A Rodie
    Division of Developmental Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow, United Kingdom
    J Soc Gynecol Investig 12:320-9. 2005
    ..We studied placental PPARdelta, PPARgamma, and retinoid X receptor alpha (RXRalpha) expression in healthy pregnancy and in preeclampsia (PET) and intrauterine growth restriction (IUGR)...