Robert Wilson

Summary

Affiliation: Royal Brompton Hospital
Country: UK

Publications

  1. ncbi request reprint A comparison of gemifloxacin and clarithromycin in acute exacerbations of chronic bronchitis and long-term clinical outcomes
    Robert Wilson
    Royal Brompton Hospital, London, England
    Clin Ther 24:639-52. 2002
  2. ncbi request reprint Oral gemifloxacin once daily for 5 days compared with sequential therapy with i.v. ceftriaxone/oral cefuroxime (maximum of 10 days) in the treatment of hospitalized patients with acute exacerbations of chronic bronchitis
    R Wilson
    Royal Brompton Hospital, London, U K
    Respir Med 97:242-9. 2003
  3. ncbi request reprint Short-term and long-term outcomes of moxifloxacin compared to standard antibiotic treatment in acute exacerbations of chronic bronchitis
    Robert Wilson
    Royal Brompton Hospital, London, UK
    Chest 125:953-64. 2004
  4. pmc Moxifloxacin versus amoxicillin/clavulanic acid in outpatient acute exacerbations of COPD: MAESTRAL results
    Robert Wilson
    Host Defence Unit, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Eur Respir J 40:17-27. 2012
  5. pmc Prognostic factors for clinical failure of exacerbations in elderly outpatients with moderate-to-severe COPD
    Robert Wilson
    Host Defence Unit, Royal Brompton Hospital, London, UK
    Int J Chron Obstruct Pulmon Dis 10:985-93. 2015
  6. doi request reprint The use of moxifloxacin for acute exacerbations of chronic obstructive pulmonary disease and chronic bronchitis
    Robert Wilson
    Royal Brompton Hospital, London, UK
    Expert Rev Respir Med 6:481-92. 2012
  7. doi request reprint Cyclical caspofungin for chronic pulmonary aspergillosis in sarcoidosis
    Gregory J Keir
    Royal Brompton Hospital, London, UK
    Thorax 69:287-8. 2014
  8. pmc Newer fluoroquinolones in the treatment of acute exacerbations of COPD
    Amit Patel
    Royal Brompton Hospital, London, UK
    Int J Chron Obstruct Pulmon Dis 1:243-50. 2006
  9. doi request reprint Bronchiectasis in yellow nail syndrome
    Georgia Woodfield
    Host Defence Unit, Royal Brompton Hospital, London, UK
    Respirology . 2016
  10. doi request reprint Respiratory infection in noncystic fibrosis bronchiectasis
    Zaid Zoumot
    Host Defence Unit, Royal Brompton Hospital, London, UK
    Curr Opin Infect Dis 23:165-70. 2010

Collaborators

Detail Information

Publications25

  1. ncbi request reprint A comparison of gemifloxacin and clarithromycin in acute exacerbations of chronic bronchitis and long-term clinical outcomes
    Robert Wilson
    Royal Brompton Hospital, London, England
    Clin Ther 24:639-52. 2002
    ..Gemifloxacin is an enhanced-affinity quinolone with potent activity against lower respiratory tract pathogens...
  2. ncbi request reprint Oral gemifloxacin once daily for 5 days compared with sequential therapy with i.v. ceftriaxone/oral cefuroxime (maximum of 10 days) in the treatment of hospitalized patients with acute exacerbations of chronic bronchitis
    R Wilson
    Royal Brompton Hospital, London, U K
    Respir Med 97:242-9. 2003
    ..A 5-day course of oral gemifloxacin was shown by this study to be at least equivalent to sequential i.v. ceftriaxone/cefuroxime axetil (for up to 10 days) in patients with AECB who require hospital treatment...
  3. ncbi request reprint Short-term and long-term outcomes of moxifloxacin compared to standard antibiotic treatment in acute exacerbations of chronic bronchitis
    Robert Wilson
    Royal Brompton Hospital, London, UK
    Chest 125:953-64. 2004
    ..To compare the effectiveness of oral moxifloxacin with standard antibiotic therapy in acute exacerbation of chronic bronchitis (AECB)...
  4. pmc Moxifloxacin versus amoxicillin/clavulanic acid in outpatient acute exacerbations of COPD: MAESTRAL results
    Robert Wilson
    Host Defence Unit, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Eur Respir J 40:17-27. 2012
    ..The MAESTRAL study showed that moxifloxacin was as effective as amoxicillin/clavulanic acid in the treatment of outpatients with AECOPD. Both therapies were well tolerated...
  5. pmc Prognostic factors for clinical failure of exacerbations in elderly outpatients with moderate-to-severe COPD
    Robert Wilson
    Host Defence Unit, Royal Brompton Hospital, London, UK
    Int J Chron Obstruct Pulmon Dis 10:985-93. 2015
    ..We aimed to identify pretherapy factors predictive of clinical failure in elderly (≥60 years old) outpatients with acute Anthonisen type 1 exacerbations...
  6. doi request reprint The use of moxifloxacin for acute exacerbations of chronic obstructive pulmonary disease and chronic bronchitis
    Robert Wilson
    Royal Brompton Hospital, London, UK
    Expert Rev Respir Med 6:481-92. 2012
    ..Moxifloxacin is a quinolone antibiotic and is one of the treatment options. This article discusses pathophysiology of these diseases, moxifloxacin clinical studies and appropriate use of moxifloxacin...
  7. doi request reprint Cyclical caspofungin for chronic pulmonary aspergillosis in sarcoidosis
    Gregory J Keir
    Royal Brompton Hospital, London, UK
    Thorax 69:287-8. 2014
    ..We report a treatment regimen of cyclical caspofungin infusions in 10 patients with sarcoidosis and worsening CPA despite oral triazoles. ..
  8. pmc Newer fluoroquinolones in the treatment of acute exacerbations of COPD
    Amit Patel
    Royal Brompton Hospital, London, UK
    Int J Chron Obstruct Pulmon Dis 1:243-50. 2006
    ..Recent antibiotic trials have compared fluoroquinolones with "standard" antibiotics and found, in the main, longer exacerbation-free intervals and better bacterial eradication rates in those treated with fluoroquinolones...
  9. doi request reprint Bronchiectasis in yellow nail syndrome
    Georgia Woodfield
    Host Defence Unit, Royal Brompton Hospital, London, UK
    Respirology . 2016
    ..Yellow nail syndrome (YNS) is a rare and poorly described disease process. In this case-control study, clinical features and findings on HRCT were compared with idiopathic bronchiectasis (IBx)...
  10. doi request reprint Respiratory infection in noncystic fibrosis bronchiectasis
    Zaid Zoumot
    Host Defence Unit, Royal Brompton Hospital, London, UK
    Curr Opin Infect Dis 23:165-70. 2010
    ..We highlight some of the main developments in the investigation and management of bronchiectasis, a condition causing susceptibility to airway infections and in more severe cases chronic bronchial suppuration...
  11. pmc A novel study design for antibiotic trials in acute exacerbations of COPD: MAESTRAL methodology
    Robert Wilson
    Host Defence Unit, Royal Brompton Hospital, London, England, UK
    Int J Chron Obstruct Pulmon Dis 6:373-83. 2011
    ..Patients are stratified according to oral corticosteroid use to control their effect across antibiotic treatment arms. Secondary endpoints include quality of life, symptom assessments and health care resource use...
  12. doi request reprint Challenges in managing Pseudomonas aeruginosa in non-cystic fibrosis bronchiectasis
    Robert Wilson
    Host Defence Unit, Royal Brompton Hospital, London, UK Electronic address
    Respir Med 117:179-89. 2016
    ..Multiple studies have found that chronic P. aeruginosa infection is associated with more severe disease and higher morbidity and mortality...
  13. doi request reprint A longitudinal study characterising a large adult primary ciliary dyskinesia population
    Anand Shah
    Host Defence Unit, Royal Brompton and Harefield NHS Foundation Trust, London, UK Imperial College London, London, UK
    Eur Respir J 48:441-50. 2016
    ....
  14. pmc Evidence of mycobacterial disease in COPD patients with lung volume reduction surgery; the importance of histological assessment of specimens: a cohort study
    Anjali Char
    Royal Brompton and Harefield NHS Foundation Trust, London, UK
    BMC Pulm Med 14:124. 2014
    ..This study examined the histology of lung tissue from COPD patients following lung volume reduction with particular focus on evidence of mycobacterial infection...
  15. pmc Ciprofloxacin dry powder for inhalation in non-cystic fibrosis bronchiectasis: a phase II randomised study
    Robert Wilson
    Host Defence Unit, Royal Brompton Hospital, London, UK
    Eur Respir J 41:1107-15. 2013
    ..Ciprofloxacin DPI 32.5 mg twice daily for 28 days was well tolerated and achieved significant reductions in total bacterial load compared with placebo in subjects with non-cystic fibrosis bronchiectasis...
  16. doi request reprint Pulmonary hypertension in patients with bronchiectasis: prognostic significance of CT signs
    Anand Devaraj
    Department of Radiology, Royal Brompton Hospital, Sydney St, London, SW3 6NP, UK
    AJR Am J Roentgenol 196:1300-4. 2011
    ..The purpose of this study was to evaluate the association between pulmonary hypertension estimated with CT and outcome among patients with bronchiectasis...
  17. doi request reprint The validity of health-related quality of life questionnaires in bronchiectasis: a systematic review and meta-analysis
    Arietta Spinou
    Division of Asthma, Allergy and Lung Biology, King s College London, Respiratory Medicine, London, UK
    Thorax 71:683-94. 2016
    ..A systematic review was conducted to evaluate their psychometric properties and assess associations between HRQOL and clinical measures...
  18. doi request reprint Predicting mortality in bronchiectasis using bronchiectasis severity index and FACED scores: a 19-year cohort study
    Huw C Ellis
    Host Defence Unit, Royal Brompton Hospital, London, UK These authors contributed equally to this paper
    Eur Respir J 47:482-9. 2016
    ..Whilst both scores had excellent predictive power, the FACED score was superior for 15-year mortality. ..
  19. ncbi request reprint Pharmacotherapy for bronchiectasis
    Michael R Loebinger
    Royal Brompton Hospital, Host Defence Unit, Fulham Road, London, SW3 6NP, UK
    Expert Opin Pharmacother 8:3183-93. 2007
    ..This article discusses the management of bronchiectasis with particular reference to the pathophysiological processes involved in the condition. It then looks at the available evidence supporting such a management plan...
  20. ncbi request reprint In vitro models of infection I--human respiratory tissue organ culture
    Andrew M Middleton
    Department of Microbiology, Royal Brompton Hospital, Host Defense Unit, Imperial College School of Science, Technology and Medicine, National Heart and Lung Institute, London, United Kingdom
    Methods Mol Med 71:277-95. 2003
  21. ncbi request reprint MOSAIC acronym
    Robert Wilson
    Chest 126:1708. 2004
  22. ncbi request reprint Endothelial dysfunction in patients with recent myocardial infarction and hyperhomocysteinaemia: effects of vitamin supplementation
    Stanley Chia
    Department of Cardiology, National Heart Centre, 17 Hospital Avenue, Singapore 168752, Republic of Singapore
    Clin Sci (Lond) 108:65-72. 2005
    ..This endothelial vasomotor dysfunction is unaltered by vitamin supplementation...
  23. ncbi request reprint Bacteria and airway inflammation in chronic obstructive pulmonary disease: more evidence
    Robert Wilson
    Am J Respir Crit Care Med 172:147-8. 2005
  24. ncbi request reprint Multiple simultaneous complications of acute otitis media in a child diagnosed with chronic granulomatous disease: a case report
    Robert Wilson
    Department of Surgery, Division of Otolaryngology, University of Kentucky College of Medicine, 800 Rose St, Lexington, KY 40536 0298, USA
    Ear Nose Throat J 87:271-2, 279. 2008
    ..The presented case should encourage physicians to investigate the possibility of an underlying immunodeficiency when treating patients with multiple simultaneous complications of acute otitis media...
  25. doi request reprint Short course of antibiotic treatment in acute exacerbations of COPD
    Robert Wilson
    Thorax 63:390-2. 2008