A M Wallace

Summary

Affiliation: Royal Infirmary
Country: UK

Publications

  1. ncbi request reprint Glucocorticoids contribute to the heritability of leptin in Scottish adult female twins
    A M Wallace
    Department of Clinical Biochemistry, Royal Infirmary, Glasgow, UK
    Clin Endocrinol (Oxf) 61:149-54. 2004
  2. pmc The changing role of the clinical laboratory in the investigation of polycystic ovarian syndrome
    A Michael Wallace
    Department of Clinical Biochemistry and Vascular Biochemistry, Glasgow Royal Infirmary, Glasgow, UK
    Clin Biochem Rev 28:79-92. 2007
  3. ncbi request reprint Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS)
    A M Wallace
    Department of Pathological Biochemistry, Glasgow Royal Infirmary, University of Glasgow, Glasgow, Scotland
    Circulation 104:3052-6. 2001
  4. ncbi request reprint Effect of weight loss and the inflammatory response on leptin concentrations in gastrointestinal cancer patients
    A M Wallace
    University Department of Clinical Biochemistry, Royal Infirmary, Glasgow, United Kingdom
    Clin Cancer Res 4:2977-9. 1998
  5. ncbi request reprint Undetectable salivary testosterone in young women with premature ovarian failure
    A Mason
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Glasgow, UK
    Clin Endocrinol (Oxf) 64:711-4. 2006
  6. ncbi request reprint The co-ordinated cytokine/hormone response to acute injury incorporates leptin
    A M Wallace
    Clinical Biochemistry, Royal Infirmary, Glasgow, UK
    Cytokine 12:1042-5. 2000
  7. doi request reprint A screening procedure for primary aldosteronism based on the Diasorin Liaison automated chemiluminescent immunoassay for direct renin
    C A Dorrian
    Department of Clinical Biochemistry, Macewen Building, Royal Infirmary, Glasgow G4 0SF, Scotland
    Ann Clin Biochem 47:195-9. 2010
  8. ncbi request reprint Variability in hydrocortisone plasma and saliva pharmacokinetics following intravenous and oral administration to patients with adrenal insufficiency
    A H Thomson
    Pharmacy Department, Western Infirmary, Glasgow, UK
    Clin Endocrinol (Oxf) 66:789-96. 2007
  9. pmc The relationship between interleukin-6 and C-reactive protein in patients with benign and malignant prostate disease
    P A McArdle
    University Department of Surgery, Royal Infirmary, Glasgow, UK
    Br J Cancer 91:1755-7. 2004
  10. ncbi request reprint Effect of variation in CYP11B1 and CYP11B2 on corticosteroid phenotype and hypothalamic-pituitary-adrenal axis activity in hypertensive and normotensive subjects
    E M Freel
    Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, G12 8TA, UK
    Clin Endocrinol (Oxf) 68:700-6. 2008

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Glucocorticoids contribute to the heritability of leptin in Scottish adult female twins
    A M Wallace
    Department of Clinical Biochemistry, Royal Infirmary, Glasgow, UK
    Clin Endocrinol (Oxf) 61:149-54. 2004
    ..The precise interactions between glucocorticoids and leptin are complex and poorly understood. The aim of the study was to investigate whether the glucocorticoid/leptin interaction is influenced by shared environmental or genetic factors...
  2. pmc The changing role of the clinical laboratory in the investigation of polycystic ovarian syndrome
    A Michael Wallace
    Department of Clinical Biochemistry and Vascular Biochemistry, Glasgow Royal Infirmary, Glasgow, UK
    Clin Biochem Rev 28:79-92. 2007
    ..We provide some explanation for confusion over the selection of the best hormone measurements for diagnosis. Finally, we outline the best current and future laboratory support for this common condition in young women...
  3. ncbi request reprint Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS)
    A M Wallace
    Department of Pathological Biochemistry, Glasgow Royal Infirmary, University of Glasgow, Glasgow, Scotland
    Circulation 104:3052-6. 2001
    ..18; 95% CI, 1.00 to 1.39; P=0.05) at the expense of C-reactive protein. CONCLUSIONS: We show, for the first time, in a large prospective study that leptin is a novel, independent risk factor for coronary heart disease...
  4. ncbi request reprint Effect of weight loss and the inflammatory response on leptin concentrations in gastrointestinal cancer patients
    A M Wallace
    University Department of Clinical Biochemistry, Royal Infirmary, Glasgow, United Kingdom
    Clin Cancer Res 4:2977-9. 1998
    ..001). Circulating leptin concentrations in the cancer patients were not altered by the presence of an inflammatory response. These results suggest that cancer anorexia/cachexia is not due to a simple dysregulation of leptin production...
  5. ncbi request reprint Undetectable salivary testosterone in young women with premature ovarian failure
    A Mason
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Glasgow, UK
    Clin Endocrinol (Oxf) 64:711-4. 2006
    ..The extent of androgen deficiency in young women with premature ovarian failure (POF) is unclear...
  6. ncbi request reprint The co-ordinated cytokine/hormone response to acute injury incorporates leptin
    A M Wallace
    Clinical Biochemistry, Royal Infirmary, Glasgow, UK
    Cytokine 12:1042-5. 2000
    ..e. stimulatory in acute and suppressive in chronic situations. They also imply a physiological role for leptin in acute injury...
  7. doi request reprint A screening procedure for primary aldosteronism based on the Diasorin Liaison automated chemiluminescent immunoassay for direct renin
    C A Dorrian
    Department of Clinical Biochemistry, Macewen Building, Royal Infirmary, Glasgow G4 0SF, Scotland
    Ann Clin Biochem 47:195-9. 2010
    ..This ratio is raised in PA and its accuracy depends on the ability to measure plasma renin at extremely low concentrations...
  8. ncbi request reprint Variability in hydrocortisone plasma and saliva pharmacokinetics following intravenous and oral administration to patients with adrenal insufficiency
    A H Thomson
    Pharmacy Department, Western Infirmary, Glasgow, UK
    Clin Endocrinol (Oxf) 66:789-96. 2007
    ..This study aimed to assess interindividual variability in cortisol pharmacokinetics and to investigate whether measurement of salivary cortisol provides a useful alternative to plasma concentration measurements...
  9. pmc The relationship between interleukin-6 and C-reactive protein in patients with benign and malignant prostate disease
    P A McArdle
    University Department of Surgery, Royal Infirmary, Glasgow, UK
    Br J Cancer 91:1755-7. 2004
    ..632, P<0.001 and rs=0.663, P<0.001, respectively. These results indicate that the relationship between interleukin-6 and C-reactive protein is similar in patients with benign and malignant prostate disease...
  10. ncbi request reprint Effect of variation in CYP11B1 and CYP11B2 on corticosteroid phenotype and hypothalamic-pituitary-adrenal axis activity in hypertensive and normotensive subjects
    E M Freel
    Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, G12 8TA, UK
    Clin Endocrinol (Oxf) 68:700-6. 2008
    ..Accordingly, we hypothesized that the reduced adrenal 11-hydroxylation may lead to chronic resetting of the pituitary-adrenal axis, with chronically increased ACTH drive resulting in aldosterone excess...
  11. ncbi request reprint Randomized, crossover comparison study of the short-term effect of oral testosterone undecanoate and intramuscular testosterone depot on linear growth and serum bone alkaline phosphatase
    S F Ahmed
    Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    J Pediatr Endocrinol Metab 17:941-50. 2004
    ..To compare the effects of oral testosterone undecanoate (TU) 40 mg daily and intramuscular depot sustanon 50 (SUS), 4 weekly, on short-term growth and bone turnover...
  12. doi request reprint The concordance between serum anti-Mullerian hormone and testosterone concentrations depends on duration of hCG stimulation in boys undergoing investigation of gonadal function
    S F Ahmed
    Department of Child Health, Royal Hospital for Sick Children, Glasgow, UK
    Clin Endocrinol (Oxf) 72:814-9. 2010
    ..In boys undergoing investigation of gonadal function, the relationship between a single measurement of serum anti-Mullerian hormone (AMH) and hCG stimulated serum testosterone is unclear...
  13. ncbi request reprint Preliminary results of a pilot study investigating the potential of salivary cortisol measurements to detect occult adrenal suppression secondary to steroid nose drops
    R S Patel
    Glasgow Royal Infirmary University NHS Trust and Royal Alexandria Hospital, Glasgow, UK
    Clin Otolaryngol Allied Sci 26:231-4. 2001
    ..Measurement of salivary cortisol is a useful, non-invasive and economical test for monitoring patients using intranasal corticosteroids...
  14. doi request reprint Comparison of the prognostic value of tumour- and patient-related factors in patients undergoing potentially curative surgery for colon cancer
    C S D Roxburgh
    University Department of Surgery, Faculty of Medicine University of Glasgow, Royal Infirmary, Glasgow, UK
    Colorectal Dis 12:987-94. 2010
    ..To comprehensively compare the prognostic value of tumour- and patient-related factors in patients undergoing curative surgery for colon cancer...
  15. ncbi request reprint Short-term growth and bone turnover in children undergoing occlusive steroid ('Wet-Wrap') dressings for treatment of atopic eczema
    R McGowan
    Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    J Dermatolog Treat 14:149-52. 2003
    ..1) respectively (not significant). Non-invasive assessment of the effects of steroid wet-wrap therapy can be performed in children with eczema. These preliminary results show no substantial growth promoting or adverse effects of therapy...
  16. pmc The response of leptin, interleukin-6 and fat oxidation to feeding in weight-losing patients with pancreatic cancer
    M D Barber
    University Department of Surgery, Royal Infirmary, Edinburgh EH3 9YW, UK
    Br J Cancer 90:1129-32. 2004
    ..05). Therefore, it would appear that low leptin concentrations, increased fat oxidation and insulin resistance are associated with increased concentrations of cortisol and interleukin-6 in weight-losing patients with pancreatic cancer...
  17. doi request reprint A 5-year-old boy with cryptorchidism and pubic hair: investigation and management of apparent male disorders of sex development in mid-childhood
    L S Keir
    Scottish Genital Anomaly Network, Yorkhill, Glasgow, UK
    Horm Res 71:87-92. 2009
    ..Late presentation of congenital adrenal hyperplasia as a 46,XX disorder of sex development due to 11-beta hydroxylase deficiency is uncommon. Such a case raises issues regarding appropriate investigation and management...
  18. pmc Testosterone measurements in early infancy
    C Tomlinson
    Department of Child Health, Royal Hospital for Sick Children, Glasgow, Scotland, UK
    Arch Dis Child Fetal Neonatal Ed 89:F558-9. 2004
    ..Expected values for male and female infants < 10 days old were 2.5-11.1 (n = 36) and 1.7-5.6 (n = 36) nmol/l respectively. For older neonates (10-50 days) the ranges were 0.2-17.2 (n = 42) and 0.1-1.5 (n = 7) nmol/l respectively...
  19. ncbi request reprint Prolonged human chorionic gonadotrophin stimulation as a tool for investigating and managing undescended testes
    J Dixon
    Department of Child Health, Royal Hospital for Sick Children, Glasgow, Scotland, UK
    Clin Endocrinol (Oxf) 67:816-21. 2007
    ..To observe the outcome in a group of children with undescended testes (UDT) given prolonged human chorionic gonadotrophin (hCG) stimulation as part of their management...
  20. doi request reprint Exaggerated adrenarche in a cohort of Scottish children: clinical features and biochemistry
    W F Paterson
    Royal Hospital for Sick Children, Glasgow, UK
    Clin Endocrinol (Oxf) 72:496-501. 2010
    ..To investigate the reported association between exaggerated adrenarche (EA) and reduced foetal growth and to identify possible risk factors for future morbidity in Scottish children with clinical features of EA...
  21. doi request reprint Recent trends and clinical features of childhood vitamin D deficiency presenting to a children's hospital in Glasgow
    S F Ahmed
    Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    Arch Dis Child 96:694-6. 2011
    ..The incidence of vitamin D deficiency is unclear in the context of continuing demographic changes and the introduction of new public health measures...
  22. pmc The relationship between circulating concentrations of C-reactive protein, inflammatory cytokines and cytokine receptors in patients with non-small-cell lung cancer
    D J McKeown
    University Department of Surgery, Royal Infirmary, Glasgow G31 2ER, UK
    Br J Cancer 91:1993-5. 2004
    ..616, P<0.001). Interleukin-6 is an important independent mediator of elevated C-reactive protein concentrations in patients with non-small-cell lung cancer...
  23. ncbi request reprint Moderate physical activity permits acute coupling between serum leptin and appetite-satiety measures in obese women
    F Tsofliou
    Human Nutrition at Glasgow, Division of Developmental Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow, Scotland
    Int J Obes Relat Metab Disord 27:1332-9. 2003
    ..To investigate whether moderate physical activity or snack intake influence appetite sensations and subsequent food intake in obese women. Associations between serum leptin and appetite ratings were also investigated...
  24. doi request reprint Measurement of 25-hydroxyvitamin D in the clinical laboratory: current procedures, performance characteristics and limitations
    A M Wallace
    Department of Clinical Biochemistry, Macewen Building, Royal Infirmary, Glasgow G4 0SF, UK
    Steroids 75:477-88. 2010
    ..Looking to the future it is hoped that the imminent introduction of a standard reference method (or methods) for 25OHD will further accelerate improvements in between method comparability...
  25. ncbi request reprint Short-term effects of prednisolone and dexamethasone on circulating concentrations of leptin and sex hormone-binding globulin in children being treated for acute lymphoblastic leukaemia
    A M Wallace
    Department of Clinical Biochemistry, Royal Infirmary, Glasgow, UK
    Clin Endocrinol (Oxf) 58:770-6. 2003
    ..This randomization process provided a suitable opportunity to compare the effects of these two administered steroid on surrogate markers of adipocyte activity (leptin) and hyperinsulinaemia/insulin resistance (SHBG)...
  26. ncbi request reprint Comparison of total, complexed and free prostate-specific antigens and their ratios in the detection of prostate cancer in a non-screened population
    P A McArdle
    University Department of Surgery, Royal Infirmary, Glasgow G31 2ER, Scotland, UK
    Ann Clin Biochem 41:201-6. 2004
    ..The role of prostate-specific antigen (PSA) isoforms in the detection of prostate cancer in a non-screened population in the UK remains to be determined...
  27. doi request reprint A multicentre evaluation of the new Beckman Coulter anti-Mullerian hormone immunoassay (AMH Gen II)
    A M Wallace
    Department Clinical Biochemistry, Glasgow Royal Infirmary, Glasgow, UK
    Ann Clin Biochem 48:370-3. 2011
    ..As a result, comparative data are urgently required between the old DSL assay and its replacement AMH Gen II...
  28. doi request reprint Effect of moderate-intensity exercise session on preprandial and postprandial responses of circulating ghrelin and appetite
    D Malkova
    Human Nutrition Section, Division of Developmental Medicine, Medical School, University of Glasgow, United Kingdom
    Horm Metab Res 40:410-5. 2008
    ..Thus, an exercise-induced increase in appetite during the later stages of recovery coinciding with the postprandial state cannot be explained by changes in the plasma concentration of total ghrelin...
  29. ncbi request reprint Endogenous corticosteroid biosynthesis in subjects after bilateral adrenalectomy
    E M Freel
    Glasgow Cardiovascular Research Centre, University of Glasgow, UK
    Clin Endocrinol (Oxf) 66:659-65. 2007
    ..We looked for evidence of extra-adrenal production of this and other corticosteroids in 10 subjects stable on long-term glucocorticoid replacement following bilateral adrenalectomy...
  30. ncbi request reprint Gender variation in leptin circadian rhythm and pulsatility in adult growth hormone deficiency: effects of growth hormone replacement
    H D White
    Department of Diabetes, Royal Liverpool University Hospital, Liverpool, UK
    Clin Endocrinol (Oxf) 58:482-8. 2003
    ..Therefore the aim of this study was to evaluate the effect of gender on circadian and pulse parameters of leptin secretion in AGHD, and examine the gender variation in response of these parameters to GHR...