Marc Lipman

Summary

Affiliation: Royal Free Hospital
Country: UK

Publications

  1. pmc Successful treatment of HIV-associated multicentric Castleman's disease and multiple organ failure with rituximab and supportive care: a case report
    Robin H Johns
    Department of Intensive Care, Royal Free Hospital, London, UK
    J Med Case Rep 4:32. 2010
  2. ncbi request reprint Immune reconstitution inflammatory syndrome in HIV
    Marc Lipman
    Department of HIV and Respiratory Medicine, Royal Free Hospital, London, UK
    Curr Opin Infect Dis 19:20-5. 2006
  3. doi request reprint Does antiretroviral therapy reduce HIV-associated tuberculosis incidence to background rates? A national observational cohort study from England, Wales, and Northern Ireland
    Rishi K Gupta
    Division of Medicine, University College London, London, UK HIV STI Department, Centre for Infectious Disease Surveillance and Control, Public Health England, London, UK Electronic address
    Lancet HIV 2:e243-51. 2015
  4. ncbi request reprint Viral breakthrough after suppression with highly active antiretroviral therapy: experience from 233 individuals with viral loads of less than 50 copies/ml followed for up to 4 years
    Fiona C Lampe
    Royal Free Centre for HIV Medicine, London, UK
    AIDS 17:768-70. 2003
  5. doi request reprint Impact of TB on the survival of people living with HIV infection in England, Wales and Northern Ireland
    Dominik Zenner
    Respiratory Diseases Department, Centre for Infectious Disease Surveillance and Control, Public Health England, London, UK Research Department of Infection and Population Health, University College London, London, UK
    Thorax 70:566-73. 2015
  6. doi request reprint Decreasing incidence of tuberculosis among heterosexuals living with diagnosed HIV in England and Wales
    Brian Rice
    Department of HIV and STI, Health Protection Agency, Health Protection Services, London, UK
    AIDS 27:1151-7. 2013
  7. ncbi request reprint The changing pattern of bronchoscopy in an HIV-infected population
    Simon Taggart
    Royal Free Hospital HIV Centre, Hampstead, London, UK
    Chest 122:878-85. 2002
  8. ncbi request reprint Pneumocystis pneumonia revisited: delayed diagnosis in an HIV infected individual with high blood and low lung CD4 T cell counts
    Ben Killingley
    The Royal Free Centre for HIV Medicine, Royal Free Hospital, London, United Kingdom
    J Infect 53:e159-60. 2006
  9. doi request reprint Migration and tuberculosis in the UK: targeting screening for latent infection to those at greatest risk of disease
    Michelle E Kruijshaar
    Tuberculosis Section, Public Health England, London, UK
    Thorax 68:1172-4. 2013
  10. doi request reprint Decreasing cost effectiveness of testing for latent TB in HIV in a low TB incidence area
    Santino Capocci
    Department of HIV and Thoracic Medicine, Royal Free London NHS Foundation Trust, London, UK
    Eur Respir J 46:165-74. 2015

Collaborators

Detail Information

Publications27

  1. pmc Successful treatment of HIV-associated multicentric Castleman's disease and multiple organ failure with rituximab and supportive care: a case report
    Robin H Johns
    Department of Intensive Care, Royal Free Hospital, London, UK
    J Med Case Rep 4:32. 2010
    ..A number of small studies have demonstrated the efficacy of the anti-CD20 monoclonal antibody, rituximab, in treating this condition...
  2. ncbi request reprint Immune reconstitution inflammatory syndrome in HIV
    Marc Lipman
    Department of HIV and Respiratory Medicine, Royal Free Hospital, London, UK
    Curr Opin Infect Dis 19:20-5. 2006
    ..The purpose of this review is to describe the epidemiology, clinical features, putative immune mechanisms and management of immune reconstitution inflammatory syndrome (IRIS) using data published in the last 2 years...
  3. doi request reprint Does antiretroviral therapy reduce HIV-associated tuberculosis incidence to background rates? A national observational cohort study from England, Wales, and Northern Ireland
    Rishi K Gupta
    Division of Medicine, University College London, London, UK HIV STI Department, Centre for Infectious Disease Surveillance and Control, Public Health England, London, UK Electronic address
    Lancet HIV 2:e243-51. 2015
    ..We compared tuberculosis incidence in people receiving ART with background rates in England, Wales, and Northern Ireland...
  4. ncbi request reprint Viral breakthrough after suppression with highly active antiretroviral therapy: experience from 233 individuals with viral loads of less than 50 copies/ml followed for up to 4 years
    Fiona C Lampe
    Royal Free Centre for HIV Medicine, London, UK
    AIDS 17:768-70. 2003
  5. doi request reprint Impact of TB on the survival of people living with HIV infection in England, Wales and Northern Ireland
    Dominik Zenner
    Respiratory Diseases Department, Centre for Infectious Disease Surveillance and Control, Public Health England, London, UK Research Department of Infection and Population Health, University College London, London, UK
    Thorax 70:566-73. 2015
    ..We calculated TB incidence rates and compared the mortality of persons with and without HIV-TB in a UK HIV cohort in the post-ART era, to determine the impact of HIV-TB on survival in the UK...
  6. doi request reprint Decreasing incidence of tuberculosis among heterosexuals living with diagnosed HIV in England and Wales
    Brian Rice
    Department of HIV and STI, Health Protection Agency, Health Protection Services, London, UK
    AIDS 27:1151-7. 2013
    ..To calculate annual tuberculosis incidence rates, and investigate risk factors for tuberculosis, among heterosexual adults living with diagnosed HIV in England and Wales...
  7. ncbi request reprint The changing pattern of bronchoscopy in an HIV-infected population
    Simon Taggart
    Royal Free Hospital HIV Centre, Hampstead, London, UK
    Chest 122:878-85. 2002
    ..This study was performed to identify any changes to our pattern of use of bronchoscopy over the last decade, and how this might relate to the introduction of more effective ARTs to our center in 1996...
  8. ncbi request reprint Pneumocystis pneumonia revisited: delayed diagnosis in an HIV infected individual with high blood and low lung CD4 T cell counts
    Ben Killingley
    The Royal Free Centre for HIV Medicine, Royal Free Hospital, London, United Kingdom
    J Infect 53:e159-60. 2006
    ..On each occasion the possibility of PCP was discounted as he had a well-preserved blood CD4 count. Subsequent examination of his pulmonary T-lymphocyte subsets revealed marked CD4 lymphopenia...
  9. doi request reprint Migration and tuberculosis in the UK: targeting screening for latent infection to those at greatest risk of disease
    Michelle E Kruijshaar
    Tuberculosis Section, Public Health England, London, UK
    Thorax 68:1172-4. 2013
    ..Numbers were the lowest in Somalian and the highest in South African and Filipino migrants, which contrasts with TB rates in these countries. Targeting screening on the basis of incidence in the UK may thus improve effectiveness. ..
  10. doi request reprint Decreasing cost effectiveness of testing for latent TB in HIV in a low TB incidence area
    Santino Capocci
    Department of HIV and Thoracic Medicine, Royal Free London NHS Foundation Trust, London, UK
    Eur Respir J 46:165-74. 2015
    ..Both UK testing regimens missed cases but are cost-effective compared with no testing. Using recent data, they all became more expensive, suggesting that alternative or more targeted TB testing strategies must be considered...
  11. pmc MMP-1 drives immunopathology in human tuberculosis and transgenic mice
    Paul Elkington
    Department of Infectious Diseases and Immunity, Imperial College London, London, UK
    J Clin Invest 121:1827-33. 2011
    ..In summary, MMP-1 may drive tissue destruction in TB and represents a therapeutic target to limit immunopathology...
  12. doi request reprint Impaired antigen-specific CD4(+) T lymphocyte responses in cavitary tuberculosis
    Simon Barry
    Department of Respiratory Medicine, Royal Free Hospital, Pond Street, London, UK
    Tuberculosis (Edinb) 89:48-53. 2009
    ..It remains unclear whether neutrophilia is a cause, or a result of cavitation in pulmonary tuberculosis...
  13. pmc Pulmonary Mycobacterium avium-intracellulare is the main driver of the rise in non-tuberculous mycobacteria incidence in England, Wales and Northern Ireland, 2007-2012
    Neeraj M Shah
    Division of Asthma, Allergy and Lung Biology, King s College London, London, UK
    BMC Infect Dis 16:195. 2016
    ..Here we report the incidence of NTM isolation in EW&NI between 2007 and 2012 from both pulmonary and extra-pulmonary samples obtained at a population level...
  14. pmc Variation in C - reactive protein response according to host and mycobacterial characteristics in active tuberculosis
    James Brown
    Department of Respiratory Medicine, Royal Free London NHS Foundation Trust, London, UK
    BMC Infect Dis 16:265. 2016
    ..tb) strain types. We report the relationship between baseline serum CRP prior to treatment and disease characteristics in a metropolitan population with TB resident in a low TB incidence region...
  15. doi request reprint Respiratory symptoms in people living with HIV and the effect of antiretroviral therapy: a systematic review and meta-analysis
    James Brown
    Departments of HIV and Respiratory Medicine, Royal Free London NHS Foundation Trust, London, UK
    Thorax . 2016
    ..However, it is not clear what this means in terms of respiratory symptoms. We sought to investigate the association between HIV status and respiratory symptoms and how these have changed with the availability of ART...
  16. doi request reprint Raising standards in UK TB control: introducing cohort review
    Charlotte Anderson
    Field Epidemiology Services Victoria, Public Health England, London, UK
    Thorax 69:187-9. 2014
    ..Cohort review enables whole system review and improvement. It has subsequently been adopted across the UK. ..
  17. doi request reprint Respiratory infections in HIV-infected adults: epidemiology, clinical features, diagnosis and treatment
    Santino Capocci
    Respiratory and HIV Medicine, University College London, Royal Free London NHS Foundation Trust, London, UK
    Curr Opin Pulm Med 19:238-43. 2013
    ..Using the evidence published over the last 2 years, this review discusses the epidemiology, diagnosis, treatment and prevention of HIV-related pulmonary infections other than mycobacterial disease...
  18. pmc Genetic variation in Mycobacterium tuberculosis isolates from a London outbreak associated with isoniazid resistance
    Giovanni Satta
    Department of Infection, Centre for Clinical Microbiology, University College London, London, UK
    BMC Med 14:117. 2016
    ..In the current study, we evaluated the genetic variation in a subset of clinical samples from the outbreak with the hypothesis that these isolates have unique biological characteristics that have served to prolong the outbreak...
  19. pmc Uniting to end the TB epidemic: advances in disease control from prevention to better diagnosis and treatment
    Ibrahim Abubakar
    Centre for Infectious Disease Epidemiology and MRC Clinical Trials Unit, University College London, London, UK
    BMC Med 14:47. 2016
    ..New research is urgently needed to support development of new vaccines and better diagnostics tools and shorter treatment for drug sensitive and resistant tuberculosis. ..
  20. pmc Incidence and risk factors for drug intolerance and association with incomplete treatment for tuberculosis: analysis of national case registers for England, Wales and Northern Ireland, 2001-2010
    Catherine Smith
    Field Epidemiology Services Cambridge, Public Health England, UK Department of Infection and Population Health, Centre for Infectious Disease Epidemiology, University College London, London, UK
    Thorax 69:956-8. 2014
    ..001). These results highlight the need for better-tolerated drug regimens and close case management of patients at risk of drug intolerance to improve treatment completion rates and contribute to more effective disease control...
  21. doi request reprint Evidence for a national problem: continued rise in tuberculosis case numbers in urban areas outside London
    Michelle E Kruijshaar
    TB Section, Respiratory Diseases Department, Health Protection Agency, Health Protection Services Colindale, London, UK
    Thorax 67:275-7. 2012
    ..Many TB control efforts focus on the capital, but with rates rising elsewhere in the country, this strategy is likely to fail in the long term...
  22. ncbi request reprint CD4 cell count changes in individuals with counts above 500 cells/mm and viral loads below 50 copies/ml on antiretroviral therapy
    Andrew N Phillips
    Royal Free Centre for HIV Medicine, London, UK
    AIDS 16:1073-5. 2002
  23. ncbi request reprint HIV and respiratory medicine
    Swapna Mandal
    The London Chest Hospital, London
    Br J Hosp Med (Lond) 69:132-6. 2008
    ..Anti-HIV drug therapy has improved the lives of many, although HIV-related respiratory complications remain extremely common worldwide...
  24. ncbi request reprint The role of flow cytometry in the interferon-gamma-based diagnosis of active tuberculosis and its coinfection with HIV-1--A technically oriented review
    George Janossy
    Department of Immunology, Royal Free and University College Medical School, London, United Kingdom
    Cytometry B Clin Cytom 74:S141-51. 2008
    ..In active TB, but not in BCG vaccinees, TB-specific memory CD4+ T cells can be found in blood that are dominantly CD27-negative and probably lung seeking and can be diagnostically useful...
  25. pmc The growing impact of HIV infection on the epidemiology of tuberculosis in England and Wales: 1999 2003
    Aliko B Ahmed
    Centre for Infections, Health Protection Agency, London NW9 5EQ, UK
    Thorax 62:672-6. 2007
    ..This study was undertaken to describe recent trends in the proportion of individuals with HIV infection among reported cases of tuberculosis in England and Wales, and to review the implications for clinical and public health care...
  26. ncbi request reprint Pseudomonal sepsis with subcutaneous nodules in an HIV-infected individual with high CD4 counts
    Shema Tariq
    J Infect 51:419-20. 2005
  27. ncbi request reprint Raised viral load in patients with viral suppression on highly active antiretroviral therapy: transient increase or treatment failure?
    Antonia L Moore
    Department of Primary Care and Population Sciences and Centre for HIV Medicine, Royal Free and University College School of Medicine, Hampstead, London NW3 2PF, UK
    AIDS 16:615-8. 2002
    ....