J P Monson

Summary

Affiliation: Queen Mary
Country: UK

Publications

  1. ncbi request reprint Primary hyperaldosteronism (Conn syndrome): MR imaging findings
    S A Sohaib
    Department of Diagnostic Imaging, Dominion House, 59 Bartholomew s Close, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, UK
    Radiology 214:527-31. 2000
  2. ncbi request reprint Biochemical markers of individual response to growth hormone replacement in adults
    J P Monson
    Department of Endocrinology, St Bartholomew s Hospital and Royal London School of Medicine and Dentistry, West Smithfield, London, UK
    Horm Res 55:49-54. 2001
  3. ncbi request reprint Sensitivity to growth hormone-the perspective. Round table discussion
    J P Monson
    Department of Endocrinology, St Bartholomew s Hospital and Royal London School of Medicine and Dentistry, West Smithfield, London, UK
    Horm Res 55:65-7. 2001
  4. ncbi request reprint Influence of growth hormone on accretion of bone mass
    J P Monson
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Horm Res 58:52-6. 2002
  5. ncbi request reprint Optimal strategy for management of pituitary disease in the growth hormone-deficient teenager
    J P Monson
    Department of Endocrinology, St Bartholomew s Hospital and the Royal London School of Medicine and Dentistry, UK
    J Pediatr Endocrinol Metab 13:1343-8. 2000
  6. ncbi request reprint Growth hormone deficiency and replacement in elderly hypopituitary adults. KIMS Study Group and the KIMS International Board. Pharmacia and Upjohn International Metabolic Database
    J P Monson
    St Bartholomew s Hospital, London, UK
    Clin Endocrinol (Oxf) 53:281-9. 2000
  7. ncbi request reprint Comparison of somatostatin analog and meta-iodobenzylguanidine radionuclides in the diagnosis and localization of advanced neuroendocrine tumors
    G Kaltsas
    Department of Endocrinology, St. Bartholomew's Hospital, London, United Kingdom EC1A 7BE
    J Clin Endocrinol Metab 86:895-902. 2001
  8. ncbi request reprint Abnormal puberty in paediatric Cushing's disease: relationship with adrenal androgen, sex hormone binding globulin and gonadotrophin concentrations
    C C Dupuis
    Department of Endocrinology, Barts and the Royal London School of Medicine and Dentistry, London, UK
    Clin Endocrinol (Oxf) 66:838-43. 2007
  9. ncbi request reprint Comparison of continuation or cessation of growth hormone (GH) therapy on body composition and metabolic status in adolescents with severe GH deficiency at completion of linear growth
    P V Carroll
    Department of Endocrinology, St Bartholomew s Hospital, London EC1A 7BE, United Kingdom
    J Clin Endocrinol Metab 89:3890-5. 2004
  10. ncbi request reprint Diagnostic performance of CT versus MR in detecting aldosterone-producing adenoma in primary hyperaldosteronism (Conn's syndrome)
    R K Lingam
    Department of Diagnostic Imaging, St Bartholomew s Hospital, West Smithfield, EC1A 7BE, London, UK
    Eur Radiol 14:1787-92. 2004

Detail Information

Publications76

  1. ncbi request reprint Primary hyperaldosteronism (Conn syndrome): MR imaging findings
    S A Sohaib
    Department of Diagnostic Imaging, Dominion House, 59 Bartholomew s Close, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, UK
    Radiology 214:527-31. 2000
    ..To describe the magnetic resonance (MR) imaging features of the adrenal glands in primary hyperaldosteronism and assess MR imaging in the detection and characterization of aldosterone-producing adenoma (APA)...
  2. ncbi request reprint Biochemical markers of individual response to growth hormone replacement in adults
    J P Monson
    Department of Endocrinology, St Bartholomew s Hospital and Royal London School of Medicine and Dentistry, West Smithfield, London, UK
    Horm Res 55:49-54. 2001
    ..Markers of bone remodelling are an important indicator of GH action within individuals, but exhibit wide inter-individual variation which limits their usefulness in defining relative GH responsiveness...
  3. ncbi request reprint Sensitivity to growth hormone-the perspective. Round table discussion
    J P Monson
    Department of Endocrinology, St Bartholomew s Hospital and Royal London School of Medicine and Dentistry, West Smithfield, London, UK
    Horm Res 55:65-7. 2001
    ....
  4. ncbi request reprint Influence of growth hormone on accretion of bone mass
    J P Monson
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Horm Res 58:52-6. 2002
    ..To date, this has been difficult to assess in adult GHD of childhood-onset because the relative contributions of low peak bone mass and increased loss of bone in later life could not be distinguished...
  5. ncbi request reprint Optimal strategy for management of pituitary disease in the growth hormone-deficient teenager
    J P Monson
    Department of Endocrinology, St Bartholomew s Hospital and the Royal London School of Medicine and Dentistry, UK
    J Pediatr Endocrinol Metab 13:1343-8. 2000
    ..The most important ingredient in this process is awareness of the situation by both pediatric and adult endocrinologists as well as the development of an agreed strategy within each clinical center...
  6. ncbi request reprint Growth hormone deficiency and replacement in elderly hypopituitary adults. KIMS Study Group and the KIMS International Board. Pharmacia and Upjohn International Metabolic Database
    J P Monson
    St Bartholomew s Hospital, London, UK
    Clin Endocrinol (Oxf) 53:281-9. 2000
    ..KIMS is a physician-managed, open, long-term surveillance study of adult GH-deficient patients receiving GH replacement. Patients were entered and data provided by interested physicians...
  7. ncbi request reprint Comparison of somatostatin analog and meta-iodobenzylguanidine radionuclides in the diagnosis and localization of advanced neuroendocrine tumors
    G Kaltsas
    Department of Endocrinology, St. Bartholomew's Hospital, London, United Kingdom EC1A 7BE
    J Clin Endocrinol Metab 86:895-902. 2001
    ..These data have implications not only for staging such tumors, but also for identifying patients who might benefit from treatment using either [(131)I]MIBG or radioactive somatostatin analogs...
  8. ncbi request reprint Abnormal puberty in paediatric Cushing's disease: relationship with adrenal androgen, sex hormone binding globulin and gonadotrophin concentrations
    C C Dupuis
    Department of Endocrinology, Barts and the Royal London School of Medicine and Dentistry, London, UK
    Clin Endocrinol (Oxf) 66:838-43. 2007
    ..Paediatric Cushing's disease is frequently associated with abnormal puberty. We addressed the hypothesis that prepubertal patients show excessive virilization and pubertal patients show suppression of LH and FSH secretion...
  9. ncbi request reprint Comparison of continuation or cessation of growth hormone (GH) therapy on body composition and metabolic status in adolescents with severe GH deficiency at completion of linear growth
    P V Carroll
    Department of Endocrinology, St Bartholomew s Hospital, London EC1A 7BE, United Kingdom
    J Clin Endocrinol Metab 89:3890-5. 2004
    ....
  10. ncbi request reprint Diagnostic performance of CT versus MR in detecting aldosterone-producing adenoma in primary hyperaldosteronism (Conn's syndrome)
    R K Lingam
    Department of Diagnostic Imaging, St Bartholomew s Hospital, West Smithfield, EC1A 7BE, London, UK
    Eur Radiol 14:1787-92. 2004
    ..There was good interobserver agreement on CT (k=0.71) and on MR (k=0.67). We have demonstrated comparable diagnostic performance and good interobserver agreement on CT and MR imaging for the detection of aldosterone-producing adenoma...
  11. doi request reprint Repeated colonoscopic screening of patients with acromegaly: 15-year experience identifies those at risk of new colonic neoplasia and allows for effective screening guidelines
    D Dworakowska
    Department of Endocrinology, Barts and the London School of Medicine, 68 Harley Street, London EC1A 7BE, UK
    Eur J Endocrinol 163:21-8. 2010
    ..It is suggested that patients with acromegaly have an increased risk of colorectal cancer and pre-malignant adenomatous polyps. However, the optimum frequency with which colonoscopic screening should be offered remains unclear...
  12. ncbi request reprint Is ovarian and adrenal venous catheterization and sampling helpful in the investigation of hyperandrogenic women?
    G A Kaltsas
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Clin Endocrinol (Oxf) 59:34-43. 2003
    ..We considered the technical success rate of catheterization, the extra information obtained in addition to the standard biochemical tests and imaging findings, and the impact of sampling on management decisions...
  13. ncbi request reprint Tumour surveillance imaging in patients with extrapituitary tumours receiving growth hormone replacement
    T T Chung
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Clin Endocrinol (Oxf) 63:274-9. 2005
    ..g. craniopharyngioma, glioma or germ cell tumours) might be anticipated to have a higher recurrence rate than secretory and nonsecretory anterior pituitary tumours...
  14. ncbi request reprint Growth hormone deficiency and replacement in patients with treated Cushing's Disease, prolactinomas and non-functioning pituitary adenomas: effects on body composition, glucose metabolism, lipid status and bone mineral density
    A Colson
    Centre for Clinical Endocrinology, St Bartholomew s Hospital, QMUL, London, UK
    Horm Res 66:257-67. 2006
    ..We report the effects of 5 years GH treatment in 124 GH deficiency adults; 42 patients with non-functioning pituitary adenomas (NFPA), 43 with treated PRL and 39 with treated CD...
  15. doi request reprint Diagnosis, management and therapeutic outcome in prepubertal Cushing's disease
    R P Dias
    Department of Endocrinology, Barts and the Royal London School of Medicine and Dentistry, London EC1A 7BE, UK
    Eur J Endocrinol 162:603-9. 2010
    ..Cushing's disease (CD) in prepubertal children is very rare and presents important diagnostic and therapeutic challenges. We report experience of the management of this subpopulation of CD patients...
  16. ncbi request reprint Computed tomography assessment of fat distribution in male and female patients with Cushing's syndrome
    A G Rockall
    Department of Diagnostic Radiology, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, UK
    Eur J Endocrinol 149:561-7. 2003
    ....
  17. ncbi request reprint Insulin-like growth factor I and the development of colorectal neoplasia in acromegaly
    P J Jenkins
    Department of Endocrinology, St Bartholomew s Hospital, London, United Kingdom
    J Clin Endocrinol Metab 85:3218-21. 2000
    ..Serum IGF-I seems to be implicated in the development of colorectal neoplasia in acromegaly, although the exact mechanisms remain uncertain...
  18. ncbi request reprint Optimal dosage interval for depot somatostatin analogue therapy in acromegaly requires individual titration
    P J Jenkins
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Clin Endocrinol (Oxf) 53:719-24. 2000
    ..However, it is uncertain whether the recommended dose intervals of 4 weeks and 10-14 days, respectively, are applicable to all patients...
  19. ncbi request reprint Treatment of metastatic carcinoid tumours, phaeochromocytoma, paraganglioma and medullary carcinoma of the thyroid with (131)I-meta-iodobenzylguanidine [(131)I-mIBG]
    J J Mukherjee
    Department of Endocrinology, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE, UK
    Clin Endocrinol (Oxf) 55:47-60. 2001
    ..It may be a valuable alternative or additional therapeutic option to the currently available conventional treatment modalities...
  20. ncbi request reprint Hexarelin as a test of pituitary reserve in patients with pituitary disease
    M Korbonits
    Departments of Endocrinology and Clinical Biochemistry, St Bartholomew s Hospital, London, United Kingdom
    Clin Endocrinol (Oxf) 51:369-75. 1999
    ..We therefore investigated whether it could be used to test GH and ACTH/cortisol reserve in patients with pituitary disease...
  21. ncbi request reprint Increased levels of insulin-like growth factor binding protein-2 in sera and tumours from patients with colonic neoplasia with and without acromegaly
    F Miraki-Moud
    Department of Endocrinology, St. Bartholomew's Hospital, London, UK
    Clin Endocrinol (Oxf) 54:499-508. 2001
    ....
  22. ncbi request reprint Hepatic steatosis in Cushing's syndrome: a radiological assessment using computed tomography
    A G Rockall
    Department of Diagnostic Radiology, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, UK
    Eur J Endocrinol 149:543-8. 2003
    ....
  23. doi request reprint The appearance of the adrenal glands on computed tomography in multiple endocrine neoplasia type 1
    S A Whitley
    Department of Diagnostic Imaging, St Bartholomew s Hospital, Barts and the London NHS Trust and QMUL, London, UK
    Eur J Endocrinol 159:819-24. 2008
    ....
  24. ncbi request reprint Safety of GH replacement in hypopituitary patients with nonirradiated pituitary and peripituitary tumours
    T T Chung
    Department of Endocrinology, St Bartholomew s Hospital, London EC1A 7BE, UK
    Clin Endocrinol (Oxf) 68:965-9. 2008
    ..However, a preponderance of patients treated with external pituitary irradiation were included...
  25. doi request reprint Gamma knife radiosurgery: a safe and effective salvage treatment for pituitary tumours not controlled despite conventional radiotherapy
    F M Swords
    Department of Oncology, Barts and The London NHS Trust, West Smithfield, London EC1A 7BE, UK
    Eur J Endocrinol 161:819-28. 2009
    ..We report the use of 'gamma knife' (GK) radiosurgery in 25 patients with pituitary adenomas not cured despite conventional therapy, including external beam radiotherapy...
  26. ncbi request reprint The effect of cessation of growth hormone (GH) therapy on bone mineral accretion in GH-deficient adolescents at the completion of linear growth
    W M Drake
    Department of Endocrinology, St Bartholomew s Hospital, London EC1A 7BE, United Kingdom
    J Clin Endocrinol Metab 88:1658-63. 2003
    ..This may predispose to clinically significant osteopenia in later adult life...
  27. ncbi request reprint Bone mineral density at diagnosis and following successful treatment of pediatric Cushing's disease
    S Scommegna
    Department of Endocrinology, St Bartholomew s Hospital, Birmingham, UK
    J Endocrinol Invest 28:231-5. 2005
    ..03 (-0.53-0.38). These findings show variability of BMD at diagnosis and near normal BMD after cure of pediatric CD, suggesting that with appropriate replacement of pituitary hormone deficiency normal peak bone mass is achievable...
  28. ncbi request reprint The effect of growth hormone replacement therapy on cortisol-cortisone interconversion in hypopituitary adults: evidence for growth hormone modulation of extrarenal 11 beta-hydroxysteroid dehydrogenase activity
    S V Gelding
    Department of Endocrinology, Royal London Hospital, UK
    Clin Endocrinol (Oxf) 48:153-62. 1998
    ..To elucidate this, we examined the effect of GH on urinary cortisol, cortisone and cortisol metabolites in hypopituitary adults at increasing doses of hydrocortisone replacement...
  29. ncbi request reprint Expression of the pituitary transcription factor Ptx-1, but not that of the trans-activating factor prop-1, is reduced in human corticotroph adenomas and is associated with decreased alpha-subunit secretion
    R H Skelly
    Department of Endocrinology, St Bartholomew s and the Royal London School of Medicine and Dentistry, London, United Kingdom
    J Clin Endocrinol Metab 85:2537-42. 2000
    ..Prop-1 expression was detected in all 34 pituitary adenomas, including 6 corticotroph adenomas and 5 gonadotroph adenomas. The expression of Prop-1 has not been described previously in these cell phenotypes...
  30. ncbi request reprint Transitional care of GH deficiency: when to stop GH therapy
    M O Savage
    Department of Endocrinology, Barts and the Royal London School of Medicine and Dentistry, London, UK
    Eur J Endocrinol 151:S61-5. 2004
    ..Quality of life does not appear to be decreased in adolescents with GHD who stop treatment, so achievement of satisfactory bone mass is a major determinant of the decision whether to continue therapy...
  31. ncbi request reprint Predicting therapeutic response and degree of pituitary tumour shrinkage during treatment of acromegaly with octreotide LAR
    P J Jenkins
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Horm Res 62:227-32. 2004
    ..This study prospectively determined the effects of the depot somatostatin analogue octreotide LAR on pituitary tumour size, GH and IGF-I levels and clinical symptoms in a cohort of previously untreated patients with acromegaly...
  32. ncbi request reprint Successful treatment of childhood-onset Cushing's disease is associated with persistent reduction in growth hormone secretion
    P V Carroll
    Department of Endocrinology, St Bartholomew s and the Royal London School of Medicine and Dentistry, London, UK
    Clin Endocrinol (Oxf) 60:169-74. 2004
    ..Whether recovery of spontaneous GH secretion occurs following treatment of childhood CD has yet to be established...
  33. ncbi request reprint Final adult height and body mass index after cure of paediatric Cushing's disease
    J H Davies
    Department of Endocrinology, Barts and the Royal London School of Medicine and Dentistry, London EC1A 7BE, UK
    Clin Endocrinol (Oxf) 62:466-72. 2005
    ..Linear growth data after cure of paediatric Cushing's disease (CD) have been reported infrequently. We evaluated final adult height (FH) and body mass index (BMI) in a cohort of paediatric patients treated successfully for CD...
  34. ncbi request reprint Successful treatment of resistant acromegaly with a growth hormone receptor antagonist
    W M Drake
    Department of Endocrinology, St Bartholomew's Hospital, London, UK
    Eur J Endocrinol 145:451-6. 2001
    ..CONCLUSIONS: Treatment with pegvisomant is safe and efficacy is maintained after 2 years. Serum IGF-I may be normalised in patients who are refractory to conventional therapy...
  35. ncbi request reprint The effect of growth hormone replacement therapy on adrenal androgen secretion in adult onset hypopituitarism
    A M Isidori
    Department of Endocrinology, Barts and The London, Queen Mary s School of Medicine and Dentistry, London, UK
    Clin Endocrinol (Oxf) 58:601-11. 2003
    ..This study examined the effects of GH replacement in GH-deficient adults on adrenal androgen secretion...
  36. doi request reprint d3-GHR genotype does not explain heterogeneity in GH responsiveness in hypopituitary adults
    V J Moyes
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Clin Endocrinol (Oxf) 72:807-13. 2010
    ..Deletion of exon 3 in the GH receptor (d3-GHR) has been linked to enhanced rhGH responsiveness in children. We investigated the role of the d3-GHR polymorphism in determining adult rhGH responsiveness...
  37. ncbi request reprint Disease activity in acromegaly may be assessed 6 weeks after discontinuation of pegvisomant
    W M Drake
    Department of Endocrinology, St Bartholomew s Hospital, London EC1A 7BE, UK
    Eur J Endocrinol 152:47-51. 2005
    ..The purpose of this study was to assess the time for which it is necessary to discontinue pegvisomant prior to biochemical reassessment of acromegaly...
  38. ncbi request reprint Sexual dimorphism of cortisol metabolism is maintained in elderly subjects and is not oestrogen dependent
    A A Toogood
    Department of Endocrinology, Christie Hospital NHS Trust, Manchester, UK
    Clin Endocrinol (Oxf) 52:61-6. 2000
    ..The aim of this study is to determine whether the sexual dimorphism of cortisol metabolism persists between post-menopausal, oestrogen-deficient women and elderly men...
  39. ncbi request reprint Benefits of screening in von Hippel-Lindau disease--comparison of morbidity associated with initial tumours in affected parents and children
    M Priesemann
    Department of Endocrinology, Barts and The London NHS Trust, London, UK
    Horm Res 66:1-5. 2006
    ..These observations strongly support the recommendation to undertake screening of the children of VHL patients...
  40. ncbi request reprint MRI of pancreatic neuroendocrine tumours
    N J Owen
    Department of Diagnostic Imaging, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE, UK
    Br J Radiol 74:968-73. 2001
    ..We review the spectrum of MRI appearances of pancreatic neuroendocrine tumours...
  41. ncbi request reprint Markers of cell proliferation in a GH-producing adenoma of a patient treated with pegvisomant
    W M Drake
    Department of Endocrinology, St Bartholomew s Hospital, West Smithfield, London, UK
    Eur J Endocrinol 153:203-5. 2005
    ....
  42. ncbi request reprint Growth in disorders of adrenal hyperfunction
    M O Savage
    Department of Endocrinology, St Bartholomew s and the Royal London School of Medicine and Dentistry, London, UK
    Horm Res 58:39-43. 2002
    ..After cure by TSS or pituitary irradiation, GH deficiency was frequent and persisted for many years. Treatment with hGH induced significant long-term catch-up growth leading to reasonable final height...
  43. ncbi request reprint Investigating familial endocrine neoplasia syndromes in children
    L B Johnston
    St Bartholomew s Hospital, London, UK
    Horm Res 55:31-5. 2001
    ..This paper provides an overview of the major features of these syndromes and suggests protocols for regular screening of children known to be at risk of developing these disorders...
  44. ncbi request reprint Optimizing gh therapy in adults and children
    W M Drake
    Department of Endocrinology, St Bartholomew s Hospital, London EC1A 7BE, United Kingdom
    Endocr Rev 22:425-50. 2001
    ....
  45. ncbi request reprint The role of 123I-diagnostic imaging in the follow-up of patients with differentiated thyroid carcinoma as compared to 131I-scanning: avoidance of negative therapeutic uptake due to stunning
    A Siddiqi
    Departments of Endocrinology, St Bartholomew's Hospital, London, UK
    Clin Endocrinol (Oxf) 55:515-21. 2001
    ..The possibility of false negative images due to the stunning phenomenon must always be borne in mind if there is a discrepancy between positive 131I imaging studies and a surprisingly negative subsequent 131I therapy scan...
  46. ncbi request reprint CT of primary hyperaldosteronism (Conn's syndrome): the value of measuring the adrenal gland
    R K Lingam
    Department of Diagnostic Imaging, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, United Kingdom
    AJR Am J Roentgenol 181:843-9. 2003
    ....
  47. ncbi request reprint The effects of growth hormone deficiency and replacement on glucocorticoid exposure in hypopituitary patients on cortisone acetate and hydrocortisone replacement
    F M Swords
    Department of Endocrinology, St Bartholomew s Hospital, West Smithfield, London, UK
    Clin Endocrinol (Oxf) 59:613-20. 2003
    ....
  48. ncbi request reprint FSH secretion predominates in vivo and in vitro in patients with non-functioning pituitary adenomas
    P L Hanson
    Department of Endocrinology, St Bartholomew s and the Royal London School of Medicine and Dentistry, London, UK
    Eur J Endocrinol 152:363-70. 2005
    ..In this study, we aimed to examine the pattern of secretion of LH and FSH from a series of pituitary adenomas cultured in vitro and where data were available to relate the results to pre-operative serum gonadotrophin levels...
  49. ncbi request reprint Suprasellar germ cell tumours: specific problems and the evolution of optimal management with a combined chemoradiotherapy regimen
    S Janmohamed
    Department of Endocrinology, St Bartholomew s Hospital, London EC1A 7BE, UK
    Clin Endocrinol (Oxf) 57:487-500. 2002
    ..We have therefore reviewed our own series of 11 such patients who were managed in a joint endocrinology/clinical oncology setting...
  50. doi request reprint Detection of neuroendocrine liver metastases with MnDPDP-enhanced MRI
    A G Rockall
    Department of Radiology, St Bartholomew s Hospital, London, UK
    Neuroendocrinology 89:288-95. 2009
    ..Our purpose was to assess the diagnostic performance of MRI, before and after administration of mangafodipir trisodium (MnDPDP), in the detection of neuroendocrine liver metastases...
  51. doi request reprint Treatment of Nelson's syndrome with temozolomide
    V J Moyes
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Eur J Endocrinol 160:115-9. 2009
    ..We propose that temozolomide is an effective and well-tolerated therapeutic tool for the treatment of Nelson's syndrome and a useful addition to the range of therapies available to treat this condition...
  52. ncbi request reprint Insulin sensitivity and glucose tolerance improve in patients with acromegaly converted from depot octreotide to pegvisomant
    W M Drake
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Eur J Endocrinol 149:521-7. 2003
    ..IS was assessed by homeostatic model assessment (HOMA) using fasting glucose and insulin concentrations and by a short insulin tolerance test (sITT). Body composition was assessed by dual energy X-ray absorptiometry...
  53. ncbi request reprint Obstructive sleep apnea presenting as pseudopheochromocytoma: a case report
    L J Hoy
    Department of Endocrinology, St Bartholomew s Hospital, London, United Kingdom EC1A 7BE
    J Clin Endocrinol Metab 89:2033-8. 2004
    ..Pseudopheochromocytoma is therefore a rare, but treatable, presentation of obstructive sleep apnea...
  54. ncbi request reprint Serum cytokines in thyrotoxicosis
    A Siddiqi
    Department of Clinical Biochemistry, St Bartholomew s and Royal London School of Medicine and Dentistry, United Kingdom
    J Clin Endocrinol Metab 84:435-9. 1999
    ....
  55. ncbi request reprint The relationship between steroidogenic factor 1 and DAX-1 expression and in vitro gonadotropin secretion in human pituitary adenomas
    S J Aylwin
    Department of Endocrinology, St Bartholomew s and the Royal London School of Medicine and Dentistry, London EC1A 7BE, United Kingdom
    J Clin Endocrinol Metab 86:2476-83. 2001
    ..SF-1 expression is associated with the in vitro secretion of LH by NFPAs. A proportion of somatotroph tumors also express SF-1 and DAX-1 and secrete gonadotropin hormones in vitro...
  56. ncbi request reprint A longitudinal study of markers of bone turnover in Graves' disease and their value in predicting bone mineral density
    A Siddiqi
    Department of Endocrinology, St Bartholomew s and The Royal London Hospital, England
    J Clin Endocrinol Metab 82:753-9. 1997
    ..Serum b-ALP indicates continuing bone formation and, at 1 yr, may provide a marker for low BMD. OC, Sdpd, and Spyr are less sensitive in documenting bone remodeling during treatment of thyrotoxicosis...
  57. ncbi request reprint Selective parathyroid venous sampling in patients with complicated hyperparathyroidism
    C M Ogilvie
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Eur J Endocrinol 155:813-21. 2006
    ..We report our experience of the use of selective parathyroid venous sampling (PVS) in the localisation of parathyroid disease in such patients...
  58. ncbi request reprint Parathyroid carcinoma in multiple endocrine neoplasia type 1 (MEN1) syndrome: two case reports of an unrecognised entity
    A Agha
    Departments of Endocrinology, St Bartholomew s Hospital, William Harvey Research Institute, Queen Mary University of London, London, UK
    J Endocrinol Invest 30:145-9. 2007
    ..In this report, we describe two further cases of parathyroid carcinoma presenting in MEN1 syndrome...
  59. pmc Clinical Use of Cinacalcet in MEN1 Hyperparathyroidism
    V J Moyes
    Department of Endocrinology, St Bartholomew s Hospital, London EC1A 7BE, UK
    Int J Endocrinol 2010:906163. 2010
    ..Cinacalcet was well tolerated by six patients; one experienced nausea and one experienced diarrhoea. Conclusion. Cinacalcet is an effective and well-tolerated medical treatment for the management of complex primary hyperparathyroidism...
  60. ncbi request reprint The relationship between pituitary tumour transforming gene (PTTG) expression and in vitro hormone and vascular endothelial growth factor (VEGF) secretion from human pituitary adenomas
    J A C Hunter
    Department of Clinical Biochemistry, St Bartholomew s and the Royal London School of Medicine and Dentistry, London, UK
    Eur J Endocrinol 148:203-11. 2003
    ....
  61. doi request reprint Circadian variation in serum cortisol during hydrocortisone replacement is not attributable to changes in cortisol-binding globulin concentrations
    T T Chung
    Department of Endocrinology, St Bartholomew s Hospital, Barts Health NHS Trust, London, UK
    Clin Endocrinol (Oxf) 84:496-500. 2016
    ....
  62. ncbi request reprint Growth hormone replacement does not increase serum prostate-specific antigen in hypopituitary men over 50 years
    C W le Roux
    Department of Endocrinology, St Bartholomew s and the Royal London School of Medicine and Dentistry, St Bartholomew s Hospital, London EC1A 7BE, UK
    Eur J Endocrinol 147:59-63. 2002
    ..The aim was to examine whether rhGH replacement in hypopituitary adults is associated with changes in serum prostate-specific antigen (PSA) as a surrogate marker of changes in prostatic growth...
  63. ncbi request reprint Indications for GH replacement in adolescents and young adults
    J P Monson
    Centre for Clinical Endocrinology, William Harvey Research Institute, St Bartholomew s Hospital, Queen Mary, University of London, London, UK
    J Endocrinol Invest 28:52-5. 2005
    ..Further studies are required to determine whether sabbatical periods off GH replacement are clinically appropriate and, if so, their reasonable duration...
  64. ncbi request reprint Treatment of advanced neuroendocrine tumours using combination chemotherapy with lomustine and 5-fluorouracil
    G A Kaltsas
    Departments of Endocrinology, St Bartholomew s Hospital, West Smithfield, London, UK
    Clin Endocrinol (Oxf) 57:169-83. 2002
    ....
  65. ncbi request reprint Pancreatic lesions in von Hippel-Lindau disease
    B Mukhopadhyay
    Departments of Endocrinology and Radiology, St Bartholomew s Hospital, West Smithfield, London, UK
    Clin Endocrinol (Oxf) 57:603-8. 2002
    ..The presence of pancreatic disease has also been variably reported. This study was undertaken to describe the prevalence, nature, natural history and clinical associations of pancreatic lesions in von Hippel-Lindau disease...
  66. ncbi request reprint The influence of gender on the short and long-term effects of growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults: a 5-year study
    W M Drake
    Department of Endocrinology, St Bartholomew's Hospital, London UK
    Clin Endocrinol (Oxf) 54:525-32. 2001
    ..This constitutes a genuine gender difference in susceptibility given that serum IGF-I was in the upper part of the reference range in all subjects...
  67. ncbi request reprint Healthcare consumption decreases in parallel with improvements in quality of life during GH replacement in hypopituitary adults with GH deficiency
    E Hernberg-Stahl
    KIGS KIMS Outcomes Research, Pharmacia AB, S 11287 Stockholm, Sweden
    J Clin Endocrinol Metab 86:5277-81. 2001
    ..001). In conclusion, GH replacement therapy, in previously untreated adults with GHD, produces significant decreases in the use of healthcare resources, which are correlated with improvements in QoL...
  68. ncbi request reprint Hypothalamo-pituitary surveillance imaging in hypopituitary patients receiving long-term GH replacement therapy
    G Frajese
    Department of Endocrinology, St. Bartholomew's Hospital, London EC1A 7BE, United Kingdom
    J Clin Endocrinol Metab 86:5172-5. 2001
    ..Similar prospective longitudinal observation of patients who have not received postoperative irradiation and comparison with rates of tumor recurrence in control series are desirable...
  69. ncbi request reprint Reductions of circulating matrix metalloproteinase 2 and vascular endothelial growth factor levels after treatment with pegvisomant in subjects with acromegaly
    A N Paisley
    Department of Endocriniology, Christie Hospital, Manchester, United Kingdom
    J Clin Endocrinol Metab 91:4635-40. 2006
    ..Patients with acromegaly have reduced life expectancy primarily due to cardiac disease...
  70. ncbi request reprint Predictors of the outcome of surgical treatment in acromegaly and the value of the mean growth hormone day curve in assessing postoperative disease activity
    G A Kaltsas
    Department of Endocrinology, St. Bartholomew's and the Royal London Hospitals, London ECIA 7BE, United Kingdom
    J Clin Endocrinol Metab 86:1645-52. 2001
    ....
  71. ncbi request reprint Consensus statement on the management of the GH-treated adolescent in the transition to adult care
    P E Clayton
    Endocrine Science Research Group, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Eur J Endocrinol 152:165-70. 2005
    ..Clinicians experienced in the care of paediatric and adult patients on GH treatment, from a wide range of countries, as well as medical representatives from the pharmaceutical manufacturers of GH participated...
  72. ncbi request reprint The influence of growth hormone deficiency, growth hormone replacement therapy, and other aspects of hypopituitarism on fracture rate and bone mineral density.
    C Wuster
    Department of Internal Medicine 1, Endocrinology and Metabolism, University Medical Clinic, Heidelberg, Germany
    J Bone Miner Res 16:398-405. 2001
    ..This increased risk appears to be attributable to GHD alone, rather than to other pituitary hormone deficiencies or to their replacement therapy...
  73. ncbi request reprint Adult growth hormone deficiency
    A M Brooke
    Department of Endocrinology, St Bartholomew s and the London, Queen Mary s, School of Medicine and Dentistry, University of London
    Clin Med 3:15-9. 2003
  74. ncbi request reprint Oral administration of the growth hormone secretagogue NN703 in adult patients with growth hormone deficiency
    J Svensson
    Research Centre for Endocrinology and Metabolism, Sahlgrenska University Hospital, Goteborg, Sweden
    Clin Endocrinol (Oxf) 58:572-80. 2003
    ..Little is known of the usefulness of GH secretagogues (GHSs) in GH-deficient (GHD) adults. The objective of this study was to determine the number of responders to treatment with NN703 in GHD adults...
  75. ncbi request reprint Stereotactic radiosurgery XVI: a treatment for previously irradiated pituitary adenomas
    F M Swords
    Department of Endocrinology, St Bartholomew s and The Royal London School of Medicine, London EC1A 7BE, United Kingdom
    J Clin Endocrinol Metab 88:5334-40. 2003
    ..Our data indicate that SMART is an effective complementary therapy for pituitary adenomas that have displayed a suboptimal response to conventional therapy including external irradiation...
  76. ncbi request reprint Role of fasting plasma glucose, glycated haemoglobin and homeostatic model assessment in the detection of glucose intolerance in adult hypopituitary patients during growth hormone replacement therapy
    A Colson
    Unit of Endocrinology and Nutrition, Cliniques Universitaires St Luc, Brussels, Belgium
    Horm Res 69:83-8. 2008
    ..This study was designed to determine the sensitivity and specificity of conventional criteria for diagnosis of impaired glucose tolerance (IGT) in a high-risk population of GH-treated GH deficient (GHD) adults...