Andrew R Leitch

Summary

Affiliation: Queen Mary
Country: UK

Publications

  1. pmc Independent, rapid and targeted loss of highly repetitive DNA in natural and synthetic allopolyploids of Nicotiana tabacum
    Simon Renny-Byfield
    School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom
    PLoS ONE 7:e36963. 2012
  2. pmc Next generation sequencing analysis reveals a relationship between rDNA unit diversity and locus number in Nicotiana diploids
    Roman Matyasek
    Institute of Biophysics, Academy of Sciences of the Czech Republic, v v i, Kralovopolska 135, Brno CZ 612 65, Czech Republic
    BMC Genomics 13:722. 2012
  3. pmc Chromosomal diversification and karyotype evolution of diploids in the cytologically diverse genus Prospero (Hyacinthaceae)
    Tae Soo Jang
    Department of Systematic and Evolutionary Botany, University of Vienna, Rennweg 14, A 1030, Vienna, Austria
    BMC Evol Biol 13:136. 2013
  4. doi request reprint Genomic plasticity and the diversity of polyploid plants
    A R Leitch
    School of Biological and Chemical Sciences, Queen Mary, University of London, London E1 4NS, UK
    Science 320:481-3. 2008
  5. pmc Similar patterns of rDNA evolution in synthetic and recently formed natural populations of Tragopogon (Asteraceae) allotetraploids
    Hana Malinska
    Institute of Biophysics, Academy of Sciences of the Czech Republic, vvi Laboratory of Molecular Epigenetics, Kralovopolska 135, CZ 61265 Brno, Czech Republic
    BMC Evol Biol 10:291. 2010
  6. pmc Rapid chromosome evolution in recently formed polyploids in Tragopogon (Asteraceae)
    K Yoong Lim
    School of Biological and Chemical Sciences, Queen Mary College, University of London, London, United Kingdom
    PLoS ONE 3:e3353. 2008
  7. ncbi request reprint Sequence of events leading to near-complete genome turnover in allopolyploid Nicotiana within five million years
    K Yoong Lim
    School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UK
    New Phytol 175:756-63. 2007
  8. doi request reprint Next generation sequencing reveals genome downsizing in allotetraploid Nicotiana tabacum, predominantly through the elimination of paternally derived repetitive DNAs
    Simon Renny-Byfield
    School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom
    Mol Biol Evol 28:2843-54. 2011
  9. doi request reprint Reconstructing the complex evolutionary origin of wild allopolyploid tobaccos (Nicotiana section suaveolentes)
    Laura J Kelly
    School of Biological and Chemical Sciences, Queen Mary University of London, E1 4NS, London, United Kingdom
    Evolution 67:80-94. 2013
  10. doi request reprint Diploidization and genome size change in allopolyploids is associated with differential dynamics of low- and high-copy sequences
    Simon Renny-Byfield
    Queen Mary University of London, School of Biological and Chemical Sciences, Mile End Road, London E1 4NS, UK
    Plant J 74:829-39. 2013

Collaborators

Detail Information

Publications20

  1. pmc Independent, rapid and targeted loss of highly repetitive DNA in natural and synthetic allopolyploids of Nicotiana tabacum
    Simon Renny-Byfield
    School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom
    PLoS ONE 7:e36963. 2012
    ..This occurs across multiple blocks of discontinuous repeats and based on the distribution of nucleotide similarity among NicCL3 units, was concurrent with rounds of sequence homogenisation...
  2. pmc Next generation sequencing analysis reveals a relationship between rDNA unit diversity and locus number in Nicotiana diploids
    Roman Matyasek
    Institute of Biophysics, Academy of Sciences of the Czech Republic, v v i, Kralovopolska 135, Brno CZ 612 65, Czech Republic
    BMC Genomics 13:722. 2012
    ..Here we study rDNA complexity in species with arrays consisting of thousands of units...
  3. pmc Chromosomal diversification and karyotype evolution of diploids in the cytologically diverse genus Prospero (Hyacinthaceae)
    Tae Soo Jang
    Department of Systematic and Evolutionary Botany, University of Vienna, Rennweg 14, A 1030, Vienna, Austria
    BMC Evol Biol 13:136. 2013
    ..hanburyi, and P. autumnale s.l., the latter comprising four diploid cytotypes. The relationship between evolutionary patterns and chromosomal variation in diploids, the basic modules of the extensive cytological diversity, is presented...
  4. doi request reprint Genomic plasticity and the diversity of polyploid plants
    A R Leitch
    School of Biological and Chemical Sciences, Queen Mary, University of London, London E1 4NS, UK
    Science 320:481-3. 2008
    ..This process has been a major driving force behind the divergence of the angiosperms and their biodiversity...
  5. pmc Similar patterns of rDNA evolution in synthetic and recently formed natural populations of Tragopogon (Asteraceae) allotetraploids
    Hana Malinska
    Institute of Biophysics, Academy of Sciences of the Czech Republic, vvi Laboratory of Molecular Epigenetics, Kralovopolska 135, CZ 61265 Brno, Czech Republic
    BMC Evol Biol 10:291. 2010
    ..We investigate the dynamics and directionality of these rDNA losses, as well as the contribution of gene copy number variation in the parental diploids to rDNA variation in the derived tetraploids...
  6. pmc Rapid chromosome evolution in recently formed polyploids in Tragopogon (Asteraceae)
    K Yoong Lim
    School of Biological and Chemical Sciences, Queen Mary College, University of London, London, United Kingdom
    PLoS ONE 3:e3353. 2008
    ..That diversity is likely important in the formation, establishment and survival of polyploid populations and species...
  7. ncbi request reprint Sequence of events leading to near-complete genome turnover in allopolyploid Nicotiana within five million years
    K Yoong Lim
    School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UK
    New Phytol 175:756-63. 2007
    ..This mode of evolution may influence or be influenced by long-term diploidization processes that characterize angiosperm polyploidy-diploid evolutionary cycles...
  8. doi request reprint Next generation sequencing reveals genome downsizing in allotetraploid Nicotiana tabacum, predominantly through the elimination of paternally derived repetitive DNAs
    Simon Renny-Byfield
    School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom
    Mol Biol Evol 28:2843-54. 2011
    ..Thus, the three genomes of N. sylvestris, N. tomentosiformis, and N. tabacum have experienced different evolutionary trajectories, with genomes that are dynamic, stable, and downsized, respectively...
  9. doi request reprint Reconstructing the complex evolutionary origin of wild allopolyploid tobaccos (Nicotiana section suaveolentes)
    Laura J Kelly
    School of Biological and Chemical Sciences, Queen Mary University of London, E1 4NS, London, United Kingdom
    Evolution 67:80-94. 2013
    ..Nicotiana exemplifies many of the factors that can complicate the reconstruction of polyploid evolutionary history and highlights how reticulate evolution at the diploid level can add even greater complexity to allopolyploid genomes...
  10. doi request reprint Diploidization and genome size change in allopolyploids is associated with differential dynamics of low- and high-copy sequences
    Simon Renny-Byfield
    Queen Mary University of London, School of Biological and Chemical Sciences, Mile End Road, London E1 4NS, UK
    Plant J 74:829-39. 2013
    ..In contrast, genome size divergence between allopolyploids is manifested through differential accumulation and/or deletion of high-copy-number sequences...
  11. pmc Genomic repeat abundances contain phylogenetic signal
    Steven Dodsworth
    School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS, UK Jodrell Laboratory, Royal Botanic Gardens, Kew, Richmond, Surrey TW9 3DS, UK School of Plant Biology, The University of Western Australia, Crawley WA 6009, Australia Institute of Plant Molecular Biology, Biology Centre ASCR, Branisovska 31, Ceske Budejovice, CZ 37005, Czech Republic Systematic Botany and Mycology, University of Munich LMU, Menzinger Straße 67, 80638 Munchen, Germany and Department of Systematic and Evolutionary Botany, University of Vienna, Rennweg 14, A 1030 Vienna, Austria School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS, UK Jodrell Laboratory, Royal Botanic Gardens, Kew, Richmond, Surrey TW9 3DS, UK School of Plant Biology, The University of Western Australia, Crawley WA 6009, Australia Institute of Plant Molecular Biology, Biology Centre ASCR, England
    Syst Biol 64:112-26. 2015
    ..At the same time as providing data for phylogenetic inference, this method additionally yields a wealth of data for comparative studies of genome evolution. ..
  12. doi request reprint Next-generation sequencing and genome evolution in allopolyploids
    Richard J A Buggs
    School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London, E1 4NS, UK
    Am J Bot 99:372-82. 2012
    ..However, recent advances in sequencing and genomics technologies now provide unprecedented opportunities to analyze numerous genetic markers in multiple individuals in any organism...
  13. pmc The effect of polyploidy and hybridization on the evolution of floral colour in Nicotiana (Solanaceae)
    Elizabeth W McCarthy
    School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS, UK, Natural History Museum, London SW7 5BD, UK, Jodrell Laboratory, Royal Botanic Gardens, Kew, Richmond, Surrey TW9 3DS, UK, Max Planck Institute for Chemical Ecology, Department of Molecular Ecology, Beutenberg Campus, Hans Knoll Strasse 8, 07745 Jena, Germany, Institute of Biophysics, Academy of Sciences of the Czech Republic, CZ 61265 Brno, Czech Republic, Institut Jean Pierre Bourgin, UMR1318 INRA AgroParisTech, INRA Versailles, 78026 Versailles Cedex, France and Department of Plant Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EA, UK School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS, UK, Natural History Museum, London SW7 5BD, UK, Jodrell Laboratory, Royal Botanic Gardens, Kew, Richmond, Surrey TW9 3DS, UK, Max Planck Institute for Chemical Ecology
    Ann Bot 115:1117-31. 2015
    ..This study investigates whether changes in floral colour can accompany polyploid and homoploid hybridization, important processes in angiosperm evolution...
  14. ncbi request reprint The signature of the Cestrum genome suggests an evolutionary response to the loss of (TTTAGGG)n telomeres
    Eva Sykorova
    School of Biological Sciences, Queen Mary, University of London, E1 4NS, UK
    Chromosoma 112:164-72. 2003
    ..The data indicate that the A/T rich minisatellite might have evolved in response to the loss of Arabidopsis-type telomeres...
  15. pmc Analysis of the giant genomes of Fritillaria (Liliaceae) indicates that a lack of DNA removal characterizes extreme expansions in genome size
    Laura J Kelly
    School of Biological and Chemical Sciences, Queen Mary University of London, London, E1 4NS, UK
    New Phytol 208:596-607. 2015
    ....
  16. doi request reprint Endogenous pararetrovirus sequences associated with 24 nt small RNAs at the centromeres of Fritillaria imperialis L. (Liliaceae), a species with a giant genome
    Hannes Becher
    School of Biological and Chemical Sciences, Queen Mary University of London, London, E1 4NS, UK
    Plant J 80:823-33. 2014
    ..Such signatures of epigenetic regulation suggest that the huge genome of F. imperialis has not arisen as a consequence of a catastrophic breakdown in the regulation of repeat amplification...
  17. pmc Flow cytometry and GISH reveal mixed ploidy populations and Spartina nonaploids with genomes of S. alterniflora and S. maritima origin
    Simon Renny-Byfield
    Queen Mary University of London, School of Biological and Chemical Sciences, London E1 4NS, UK
    Ann Bot 105:527-33. 2010
    ..x townsendii (2n = 60) and a derived allododecaploid S. anglica (2n = 120, 122, 124); the latter two are considered to have originated in Hythe, southern England at the end of the 19th century...
  18. doi request reprint Genome size diversity in angiosperms and its influence on gene space
    Steven Dodsworth
    School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS, UK
    Curr Opin Genet Dev 35:73-8. 2015
    ..Here we review these new findings and explore in what ways genome size itself plays a role in influencing how repeats impact genome dynamics and gene space, including gene expression. ..
  19. ncbi request reprint Comparative genomics and repetitive sequence divergence in the species of diploid Nicotiana section Alatae
    K Yoong Lim
    School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UK
    Plant J 48:907-19. 2006
    ..This rapid rate of divergence is analogous to that found in polyploid species, and is therefore, in plants, not only associated with polyploidy...
  20. doi request reprint Impact of genomic diversity in river ecosystems
    Andrew R Leitch
    School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London, E1 4NS, UK
    Trends Plant Sci 19:361-6. 2014
    ....