Affiliation: North Hampshire Hospital
- Hyperthermic intraperitoneal chemotherapy and cytoreductive surgery for peritoneal carcinomatosis of colorectal origin: a novel treatment strategy with promising results in selected patientsB J Moran
Pseudomyxoma Peritonei Centre, North Hampshire Hospital, Basingstoke, Hampshire RG24 9NA, UK
Colorectal Dis 8:544-50. 2006..Selected patients with localized disease have been shown to have good outcomes with prolonged survival and perhaps a possibility of cure...
- Early results of surgery in 123 patients with pseudomyxoma peritonei from a perforated appendiceal neoplasmElizabeth M Murphy
Pseudomyxoma Peritonei Centre, Colorectal Research Unit, North Hampshire Hospital, Basingstoke, Hampshire, United Kingdom
Dis Colon Rectum 50:37-42. 2007..We report the operative findings, pathologic assessment, and early outcomes in 123 consecutive patients with a perforated appendiceal neoplasm presenting as pseudomyxoma peritonei...
- Establishment of a peritoneal malignancy treatment centre in the United KingdomBrendan J Moran
NSCAG Pseudomyxoma Peritonei Centre, North Hampshire Hospital, Basingstoke, Hampshire RG24 9NA, UK
Eur J Surg Oncol 32:614-8. 2006..The surgical skill, with its associated learning curve, and some early results of treatment are presented with the hope that such an experience may be of help to others...
- Decision-making and technical factors account for the learning curve in complex surgeryB J Moran
Pseudomyxoma Peritonei Centre, North Hampshire Hospital, Aldermaston Road, Basingstoke, Hampshire, RG24 9NA, UK
J Public Health (Oxf) 28:375-8. 2006..However, it is improbable that technical and innovative skills can be developed, or optimized, without some aspects of learning by experience and indeed 'risk taking'...
- Clarifying the TNM staging of rectal cancer in the context of modern imaging and neo-adjuvant treatment: 'y''u' and 'p' need 'mr' and 'ct'B Moran
United Kingdom National Multidisciplinary Team MDT, Total Mesorectal Excision TME Development Programme, Pelican Centre, North Hampshire Hospital, Basingstoke, UK
Colorectal Dis 10:242-3. 2008....
- Late-onset fistula presenting as buttock abscess in two patients with ileo-anal J-pouches for ulcerative colitisS Banerjee
Colorectal Research Unit, North Hampshire Hospital, Aldermaston Road, Basingstoke RG24 9NA, UK
Tech Coloproctol 8:37-9. 2004..The possibility that these unusual fistulae might be more common following removal of the mesorectum rather than a close rectal dissection is explored...
- The etiology, clinical presentation, and management of pseudomyxoma peritoneiBrendan J Moran
Pseudomyxoma Peritonei Centre, North Hampshire Hospital, Aldermaston Road, Basingstoke, Hampshire, RG24 9NA, United Kingdom
Surg Oncol Clin N Am 12:585-603. 2003..The search continues for safer, less aggressive treatments, but is hampered by a lack of hard evidence and the absence of experimental animal or human models to evaluate emerging strategies...
- Adhesion-related small bowel obstructionB J Moran
Colorectal Research Unit, North Hampshire Hospital, Basingstoke, Hampshire, UK
Colorectal Dis 9:39-44. 2007..Adhesive SBO remains a common surgical emergency and there is no substitute for repeated examination by a surgeon, capable of performing a laparotomy, in the optimal management of these complex patients...
- Operability and early outcome in 100 consecutive laparotomies for peritoneal malignancyB J Moran
Pseudomyxoma Peritonei Centre, North Hampshire Hospital, Aldermaston Road, Basingstoke RG24 9NA, UK
Br J Surg 93:100-4. 2006..Initial experience with 100 consecutive laparotomies is reported...
- Preoperative MRI sphincter morphology and anal manometry: can they be markers of functional outcome following anterior resection for rectal cancer?P How
Pelican Cancer Foundation, Dinwoodie Drive, Basingstoke, UK
Colorectal Dis 14:e339-45. 2012..This study looked at whether sphincter complex measurements recorded from preoperative staging MRIs and preoperative anal manometry have any correlation with functional outcome...
- A systematic review of cancer related patient outcomes after anterior resection and abdominoperineal excision for rectal cancer in the total mesorectal excision eraP How
Pelican Cancer Foundation, The Ark, Dinwoodie Drive, Basingstoke, RG24 9NN, UK
Surg Oncol 20:e149-55. 2011..However, some centres have demonstrated better outcomes with APE. We conducted a systematic review of high-quality studies within the total mesorectal excision (TME) era comparing outcomes of AR and APE...
- Comparative quality of life in patients following abdominoperineal excision and low anterior resection for low rectal cancerP How
Pelican Cancer Foundation, Basingstoke, UK
Dis Colon Rectum 55:400-6. 2012..It is widely believed that quality of life is worse after abdominoperineal excision then after low anterior resection. However, this view is not supported unequivocally...
- Elevated tumour markers prior to complete tumour removal in patients with pseudomyxoma peritonei predict early recurrenceF Alexander-Sefre
The North Hampshire Hospital, Basingstoke, UK
Colorectal Dis 7:382-6. 2005..To assess the potential value of pre-operative CEA, CA 125 and CA 19-9 in identifying Pseudomyxoma peritonei (PMP) patients at risk of recurrence following complete cytoreductive surgery and intraperitoneal chemotherapy...
- Sites of surgical wasting in the abdominoperineal specimenG Salerno
Pelican Cancer Foundation, North Hampshire Hospital, Basingstoke, London, UK
Br J Surg 95:1147-54. 2008..This is associated with high positive margin rates. The aim of this study was to locate the site of surgical wasting, namely the least amount of tissue excised at APE...
- Elevated tumour markers are normalized in most patients with pseudomyxoma peritonei 7 days after complete tumour removalF Di Fabio
Peritoneal Malignancy Institute and Colorectal Surgery, Basingstoke and North Hampshire Hospitals, Basingstoke, UK
Colorectal Dis 17:698-703. 2015..The aim of the study was to compare the tumour markers 7 days after surgery in patients with elevated preoperative levels...
- Reducing the incidence and managing the consequences of anastomotic leakage after rectal resectionB Meade
Colorectal Research Unit, North Hampshire Hospital, Basingstoke, UK
Acta Chir Iugosl 51:19-23. 2004..Faecal diversion should be regarded as the optimal safety measure to reduce the consequences of leakage and to mange leakage of an unprotected anastomosis...
- A protocol for management of blood loss in surgical treatment of peritoneal malignancy by cytoreductive surgery and hyperthermic intraperitoneal chemotherapyN Sargant
Department of Haematology, Hampshire Hospitals NHS Trust, Basingstoke, UK
Transfus Med 26:118-22. 2016..A comparison was made with a cohort of patients treated with fresh frozen plasma (FFP) alone. The secondary aim was to measure the effect of both protocols on coagulation parameters and the incidence of arterial or venous thrombosis...
- The results of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in 1200 patients with peritoneal malignancyB Moran
Peritoneal Malignancy Institute, North Hampshire Hospital, Hampshire Hospital Foundation Trust, Basingstoke, UK
Colorectal Dis 17:772-8. 2015..The study determined the outcome of 1200 consecutive patients treated for peritoneal malignancy in one surgical unit over a 20-year period...
- CT in pseudomyxoma peritonei: a review of 17 casesT V C Sulkin
Departments of Clinical Radiology, North Hampshire Hospital NHS Trust, Basingstoke, UK
Clin Radiol 57:608-13. 2002..To describe the computed tomography (CT) findings in pseudomyxoma peritonei...
- Total mesorectal excision results in low local recurrence rates in lymph node-positive rectal cancerThomas D Cecil
Colorectal Research Unit, North Hampshire Hospital, Basingstoke, United Kingdom
Dis Colon Rectum 47:1145-9; discussion 1149-50. 2004..If total mesorectal excision provides adequate block dissection of the lymphatics of the rectum, good local control with low rates of local recurrence should be achieved even in node-positive disease...
- Morbidity and mortality with cytoreductive surgery and intraperitoneal chemotherapy: the importance of a learning curveFaheez Mohamed
Pseudomyxoma Peritonei Centre, Basingstoke and North Hampshire Hospital Foundation Trust, Hampshire, UK
Cancer J 15:196-9. 2009....
- Magnetic resonance imaging prediction of an involved surgical resection margin in low rectal cancerGisella V Salerno
Pelican Cancer Foundation, North Hampshire Hospital, Basingstoke, Hampshire, United Kingdom
Dis Colon Rectum 52:632-9. 2009..The aim of this study was to assess positive resection margin prediction by using magnetic resonance imaging staging...
- MRI staging of low rectal cancerOliver C Shihab
Pelican Cancer Foundation, North Hampshire Hospital, Basingstoke, UK
Eur Radiol 19:643-50. 2009..Using this staging system it is possible for the radiologist to demonstrate accurately tumour-free planes for surgical excision of low rectal tumours...
- Published evidence favors the use of suprapubic catheters in pelvic colorectal surgeryGraham W Branagan
Department of Surgery, The North Hampshire Hospital, Basingstoke, United Kingdom
Dis Colon Rectum 45:1104-8. 2002..However, in gynecologic surgery suprapubic catheters are commonly used and are reported to be superior to urethral catheters...
- Rectal cancer in the elderly: patients' perception of bowel control after restorative surgeryP Seamus Phillips
Colorectal Research Unit, North Hampshire Hospital, Basingstoke, United Kingdom
Dis Colon Rectum 47:287-90. 2004..To investigate this, we reviewed functional results one year after restorative surgery in patients older than aged 75 years...
- Initiation of a program in peritoneal surface malignancyLuis González Bayón
Hospital Universitario Gregorio Maranon, C Dr Esquerdo, 46, 28007 Madrid, Spain
Surg Oncol Clin N Am 12:741-53. 2003..This manuscript provides a guide for implementation of this treatment strategy with a minimum of untoward events, reduced apprehension of medical and nursing colleagues, and a maximum benefit for patients...
- Laparoscopic colorectal cancer surgery: a hammer looking for a nail?Brendan J Moran
Department of Surgery, North Hampshire Hospital, Basingstoke, Hants, UK
Ann R Coll Surg Engl 86:300-1. 2004
- Four percent of patients undergoing colorectal cancer surgery may have synchronous appendiceal neoplasiaMuhammad Najm Khan
Department of Colorectal Surgery, North Hampshire Hospital NHS Trust, Basingstoke, RG24 9NA, United Kingdom
Dis Colon Rectum 50:1856-9. 2007..A special interest of the senior author in appendiceal and rectal cancer has prompted routine removal of the appendix in all cases undergoing surgery for colorectal cancer...