Michael J Gilchrist

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. pmc Exon capture and bulk segregant analysis: rapid discovery of causative mutations using high-throughput sequencing
    Florencia del Viso
    Department of Pediatrics and Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
    BMC Genomics 13:649. 2012
  2. doi request reprint Databases of gene expression in Xenopus development
    Michael J Gilchrist
    Division of Systems Biology, MRC National Institute for Medical Research, London, UK
    Methods Mol Biol 917:319-45. 2012
  3. pmc From expression cloning to gene modeling: the development of Xenopus gene sequence resources
    Michael J Gilchrist
    Division of Systems Biology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom
    Genesis 50:143-54. 2012
  4. pmc A study of alternative splicing in the pig
    Ann Britt Nygard
    University of Copenhagen, Faculty of Life Sciences, Department of Basic Animal and Veterinary Sciences, Division of Genetics and Bioinformatics, Groennegaardsvej 3, 1870 Frederiksberg C, Denmark
    BMC Res Notes 3:123. 2010
  5. pmc Genome-wide analysis of gene expression during Xenopus tropicalis tadpole tail regeneration
    Nick R Love
    Faculty of Life Sciences, University of Manchester, UK
    BMC Dev Biol 11:70. 2011
  6. pmc Molecular asymmetry in the 8-cell stage Xenopus tropicalis embryo described by single blastomere transcript sequencing
    Elena De Domenico
    The Francis Crick Institute, Mill Hill Laboratory, The Ridgeway, Mill Hill, London NW7 1AA, UK
    Dev Biol 408:252-68. 2015
  7. pmc High-resolution analysis of gene activity during the Xenopus mid-blastula transition
    Clara Collart
    Division of Systems Biology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
    Development 141:1927-39. 2014

Collaborators

  • James C Smith
  • Nicolas Pollet
  • Elena De Domenico
  • Nick D L Owens
  • Clara Collart
  • Florencia del Viso
  • Nick R Love
  • Ann Britt Nygard
  • Ian M Grant
  • Rosa Gomes-Faria
  • Brook Cooper
  • Ilya Patrushev
  • Abdul K Sesay
  • Leena Bhaw-Rosun
  • Mustafa K Khokha
  • Yong Kong
  • Dipankan Bhattacharya
  • Timothy J Mohun
  • Boyan Bonev
  • Yaoyao Chen
  • Robert Lea
  • Lynne Fairclough
  • Leo A H Zeef
  • Enrique Amaya
  • Roberto Paredes
  • Jan Gorodkin
  • Susanna Cirera
  • Merete Fredholm
  • Claus B Jørgensen

Detail Information

Publications7

  1. pmc Exon capture and bulk segregant analysis: rapid discovery of causative mutations using high-throughput sequencing
    Florencia del Viso
    Department of Pediatrics and Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
    BMC Genomics 13:649. 2012
    ..To facilitate cloning of X. tropicalis mutants identified in forward genetic screens, we sought to combine bulk segregant analysis and exome sequencing into a single step...
  2. doi request reprint Databases of gene expression in Xenopus development
    Michael J Gilchrist
    Division of Systems Biology, MRC National Institute for Medical Research, London, UK
    Methods Mol Biol 917:319-45. 2012
    ..Instructions are given on how to access and interpret the data provided by the NCBI Gene database, Xenbase, and the Xenopus full-length EST, quickImage, and Xenmark databases...
  3. pmc From expression cloning to gene modeling: the development of Xenopus gene sequence resources
    Michael J Gilchrist
    Division of Systems Biology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom
    Genesis 50:143-54. 2012
    ..In addition, I demonstrate that the gaps in the current genome assembly create problems for the computational elucidation of gene sequences, and suggest some ways to ameliorate the effects of this...
  4. pmc A study of alternative splicing in the pig
    Ann Britt Nygard
    University of Copenhagen, Faculty of Life Sciences, Department of Basic Animal and Veterinary Sciences, Division of Genetics and Bioinformatics, Groennegaardsvej 3, 1870 Frederiksberg C, Denmark
    BMC Res Notes 3:123. 2010
    ..With the EST resource for the domestic pig now containing more than one million porcine ESTs, it is possible to identify alternative splice forms of the individual transcripts in this species from the EST data with some confidence...
  5. pmc Genome-wide analysis of gene expression during Xenopus tropicalis tadpole tail regeneration
    Nick R Love
    Faculty of Life Sciences, University of Manchester, UK
    BMC Dev Biol 11:70. 2011
    ..Here, we explore tadpole tail regeneration in Xenopus tropicalis, a diploid frog with a sequenced genome...
  6. pmc Molecular asymmetry in the 8-cell stage Xenopus tropicalis embryo described by single blastomere transcript sequencing
    Elena De Domenico
    The Francis Crick Institute, Mill Hill Laboratory, The Ridgeway, Mill Hill, London NW7 1AA, UK
    Dev Biol 408:252-68. 2015
    ..Mutations in the human ortholog of the most animally enriched novel gene, Slc35d1, are causative for Schneckenbecken dysplasia, and we show that a similar phenotype is produced by depletion of the orthologous protein in Xenopus embryos. ..
  7. pmc High-resolution analysis of gene activity during the Xenopus mid-blastula transition
    Clara Collart
    Division of Systems Biology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
    Development 141:1927-39. 2014
    ..Together, our high-resolution time series and experimental studies have yielded a deeper understanding of the temporal organisation of gene regulatory networks in the early Xenopus embryo. ..