Ross A Breckenridge

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. ncbi request reprint Overexpression of the transcription factor Hand1 causes predisposition towards arrhythmia in mice
    Ross A Breckenridge
    MRC National Institute for Medical Research, Mill Hill, London NW7 1AA, UK
    J Mol Cell Cardiol 47:133-41. 2009
  2. doi request reprint Heart failure and mouse models
    Ross Breckenridge
    MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London, NW7 1AA, UK
    Dis Model Mech 3:138-43. 2010
  3. pmc A mouse model to study the link between hypoxia, long QT interval and sudden infant death syndrome
    Marianne T Neary
    Developmental Biology, MRC National Institute for Medical Research, London, NW7 1AA, UK
    Dis Model Mech 6:503-7. 2013
  4. pmc Abundance, distribution, mobility and oligomeric state of M₂ muscarinic acetylcholine receptors in live cardiac muscle
    Tatiana A Nenasheva
    Division of Physical Biochemistry, MRC National Institute for Medical Research, Mill Hill, London NW7 1AA, UK
    J Mol Cell Cardiol 57:129-36. 2013
  5. ncbi request reprint Isolated left ventricular non-compaction: the case for abnormal myocardial development
    Ross A Breckenridge
    Department of Clinical Pharmacology, BHF Laboratories, University College, London
    Cardiol Young 17:124-9. 2007
  6. ncbi request reprint A role for Dimethylarginine Dimethylaminohydrolase 1 (DDAH1) in mammalian development
    Ross A Breckenridge
    Centre for Clinical Pharmacology, University College London, BHF Laboratories, London, UK
    Int J Dev Biol 54:215-20. 2010
  7. pmc Hypoxia at the heart of sudden infant death syndrome?
    Marianne T Neary
    MRC National Institute for Medical Research, Mill Hill, London, UK
    Pediatr Res 74:375-9. 2013
  8. pmc Hypoxia signaling controls postnatal changes in cardiac mitochondrial morphology and function
    Marianne T Neary
    MRC National Institute for Medical Research, Mill Hill, London NW7 1AA
    J Mol Cell Cardiol 74:340-52. 2014
  9. pmc Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism
    Ross A Breckenridge
    Developmental Biology, MRC National Institute for Medical Research, London, United Kingdom Division of Medicine, University College London, London, United Kingdom
    PLoS Biol 11:e1001666. 2013

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Overexpression of the transcription factor Hand1 causes predisposition towards arrhythmia in mice
    Ross A Breckenridge
    MRC National Institute for Medical Research, Mill Hill, London NW7 1AA, UK
    J Mol Cell Cardiol 47:133-41. 2009
    ..We propose that cardiac overexpression of Hand1 offers a useful mouse model of arrhythmogenesis and elevated HAND1 may provide one of the molecular links between the failing heart and arrhythmia...
  2. doi request reprint Heart failure and mouse models
    Ross Breckenridge
    MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London, NW7 1AA, UK
    Dis Model Mech 3:138-43. 2010
    ..This review outlines the mouse models of heart failure in common usage today, and discusses how adaptations in these models may allow easier translation of animal experimentation into the clinical arena...
  3. pmc A mouse model to study the link between hypoxia, long QT interval and sudden infant death syndrome
    Marianne T Neary
    Developmental Biology, MRC National Institute for Medical Research, London, NW7 1AA, UK
    Dis Model Mech 6:503-7. 2013
    ..This is consistent with known risk factors of SIDS and provides a link between neonatal hypoxia, ECG abnormalities and sudden death...
  4. pmc Abundance, distribution, mobility and oligomeric state of M₂ muscarinic acetylcholine receptors in live cardiac muscle
    Tatiana A Nenasheva
    Division of Physical Biochemistry, MRC National Institute for Medical Research, Mill Hill, London NW7 1AA, UK
    J Mol Cell Cardiol 57:129-36. 2013
    ..Our estimated encounter rate of 5-10 collisions per second, may explain the latency between acetylcholine application and GIRK channel opening...
  5. ncbi request reprint Isolated left ventricular non-compaction: the case for abnormal myocardial development
    Ross A Breckenridge
    Department of Clinical Pharmacology, BHF Laboratories, University College, London
    Cardiol Young 17:124-9. 2007
    ..Experimental work in animal models provides several candidate transcription factors and signalling molecules that could, in theory, cause ventricular non-compaction if disrupted...
  6. ncbi request reprint A role for Dimethylarginine Dimethylaminohydrolase 1 (DDAH1) in mammalian development
    Ross A Breckenridge
    Centre for Clinical Pharmacology, University College London, BHF Laboratories, London, UK
    Int J Dev Biol 54:215-20. 2010
    ..These expression patterns implicate DDAH1 and DDAH2 in embryonic development, possibly through specific effects on nitric oxide pathways...
  7. pmc Hypoxia at the heart of sudden infant death syndrome?
    Marianne T Neary
    MRC National Institute for Medical Research, Mill Hill, London, UK
    Pediatr Res 74:375-9. 2013
    ..Our model may integrate several epidemiological findings related to risks factors for SIDS, and agrees with previous work suggesting a common final pathological pathway in SIDS. ..
  8. pmc Hypoxia signaling controls postnatal changes in cardiac mitochondrial morphology and function
    Marianne T Neary
    MRC National Institute for Medical Research, Mill Hill, London NW7 1AA
    J Mol Cell Cardiol 74:340-52. 2014
    ..We therefore propose that the increase in ambient oxygen encountered by the neonate at birth acts as a key physiological stimulus to cardiac mitochondrial adaptation. ..
  9. pmc Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism
    Ross A Breckenridge
    Developmental Biology, MRC National Institute for Medical Research, London, United Kingdom Division of Medicine, University College London, London, United Kingdom
    PLoS Biol 11:e1001666. 2013
    ..Understanding hypoxia adaptation in the fetal heart may allow development of strategies to protect cardiomyocytes vulnerable to ischaemia, for example during cardiac ischaemia or surgery. ..