D J Anstee

Summary

Affiliation: National Blood Service
Country: UK

Publications

  1. ncbi request reprint Novel secreted isoform of adhesion molecule ICAM-4: potential regulator of membrane-associated ICAM-4 interactions
    Gloria Lee
    Life Sciences Division, University of California, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Blood 101:1790-7. 2003
  2. doi request reprint alpha-Hemoglobin stabilizing protein is not a suitable marker for a screening test for variant Creutzfeldt-Jakob disease
    Nigel E J Appleford
    Bristol Institute for Transfusion Sciences, National Blood Service, Bristol, UK
    Transfusion 48:1616-26. 2008
  3. ncbi request reprint Progress towards a blood test for vCJD?
    David J Anstee
    Bristol Institute for Transfusion Sciences, Bristol, UK
    Vox Sang 83:203-5. 2002
  4. ncbi request reprint Prion protein and the red cell
    David J Anstee
    Bristol Institute for Transfusion Sciences, National Blood Service, Bristol, UK
    Curr Opin Hematol 14:210-4. 2007
  5. ncbi request reprint Whatomics
    D J Anstee
    Bristol Institute for Transfusion Sciences, Southmead Road, Bristol BS10 5ND, UK
    Vox Sang 87:13-4. 2004
  6. ncbi request reprint Lutheran blood group glycoprotein and its newly characterized mouse homologue specifically bind alpha5 chain-containing human laminin with high affinity
    S F Parsons
    Bristol Institute for Transfusion Sciences, Bristol, United Kingdom
    Blood 97:312-20. 2001
  7. ncbi request reprint The expression of human blood group antigens during erythropoiesis in a cell culture system
    M J Southcott
    Department of Biochemistry, School of Medical Sciences, University of Bristol, Bristol, UK
    Blood 93:4425-35. 1999
  8. ncbi request reprint Erythroid cell adhesion molecules Lutheran and LW in health and disease
    S F Parsons
    Bristol Institute for Transfusion Sciences, UK
    Baillieres Best Pract Res Clin Haematol 12:729-45. 1999
  9. ncbi request reprint Expression of C antigen in transduced K562 cells
    J S Smythe
    International Blood Group Reference Laboratory, Bristol Institute for Transfusion Sciences, Bristol, UK
    Transfusion 41:24-30. 2001
  10. ncbi request reprint Intercellular adhesion molecule-4 binds alpha(4)beta(1) and alpha(V)-family integrins through novel integrin-binding mechanisms
    F A Spring
    Bristol Institute for Transfusion Sciences, United Kingdom
    Blood 98:458-66. 2001

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Novel secreted isoform of adhesion molecule ICAM-4: potential regulator of membrane-associated ICAM-4 interactions
    Gloria Lee
    Life Sciences Division, University of California, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Blood 101:1790-7. 2003
    ..We postulate that secretion of this newly described isoform, ICAM-4S, may modulate binding of membrane-associated ICAM-4 and could thus play a critical regulatory role in erythroblast molecular attachments...
  2. doi request reprint alpha-Hemoglobin stabilizing protein is not a suitable marker for a screening test for variant Creutzfeldt-Jakob disease
    Nigel E J Appleford
    Bristol Institute for Transfusion Sciences, National Blood Service, Bristol, UK
    Transfusion 48:1616-26. 2008
    ..alpha-Hemoglobin stabilizing protein (AHSP; syn. ERAF, EDRF) transcript levels are reduced in the blood of mice incubating transmissible spongiform encephalopathy...
  3. ncbi request reprint Progress towards a blood test for vCJD?
    David J Anstee
    Bristol Institute for Transfusion Sciences, Bristol, UK
    Vox Sang 83:203-5. 2002
  4. ncbi request reprint Prion protein and the red cell
    David J Anstee
    Bristol Institute for Transfusion Sciences, National Blood Service, Bristol, UK
    Curr Opin Hematol 14:210-4. 2007
    ..This review focuses on transfusion-transmission of variant Creutzfeldt-Jakob disease by red cell preparations...
  5. ncbi request reprint Whatomics
    D J Anstee
    Bristol Institute for Transfusion Sciences, Southmead Road, Bristol BS10 5ND, UK
    Vox Sang 87:13-4. 2004
  6. ncbi request reprint Lutheran blood group glycoprotein and its newly characterized mouse homologue specifically bind alpha5 chain-containing human laminin with high affinity
    S F Parsons
    Bristol Institute for Transfusion Sciences, Bristol, United Kingdom
    Blood 97:312-20. 2001
    ..These results further support a role for Lu gps in sickle cell disease and indicate the utility of mouse models to explore the function of Lu gp-laminin 10/11 interaction in normal erythropoiesis and in sickle cell disease...
  7. ncbi request reprint The expression of human blood group antigens during erythropoiesis in a cell culture system
    M J Southcott
    Department of Biochemistry, School of Medical Sciences, University of Bristol, Bristol, UK
    Blood 93:4425-35. 1999
    ..Rh c antigen appeared before Rh D antigen, and it is suggested that this may reflect a reorganization of the developing erythroid cell membrane involving the Rh polypeptides and other components, including GPA and Band 3...
  8. ncbi request reprint Erythroid cell adhesion molecules Lutheran and LW in health and disease
    S F Parsons
    Bristol Institute for Transfusion Sciences, UK
    Baillieres Best Pract Res Clin Haematol 12:729-45. 1999
    ..These data suggest that the Lu and LW molecules may contribute to the vaso-occlusive events associated with episodes of acute pain in sickle cell disease...
  9. ncbi request reprint Expression of C antigen in transduced K562 cells
    J S Smythe
    International Blood Group Reference Laboratory, Bristol Institute for Transfusion Sciences, Bristol, UK
    Transfusion 41:24-30. 2001
    ..A retrovirus-expression system was previously used to show that polypeptides carrying the Rh blood group antigens are encoded by the RHD and RHCE genes. This study investigated the structure of the C antigen...
  10. ncbi request reprint Intercellular adhesion molecule-4 binds alpha(4)beta(1) and alpha(V)-family integrins through novel integrin-binding mechanisms
    F A Spring
    Bristol Institute for Transfusion Sciences, United Kingdom
    Blood 98:458-66. 2001
    ..These findings suggest a role for ICAM-4 in normal erythropoiesis and may also be relevant to the adhesive interactions of sickle cells...
  11. doi request reprint Production of erythroid cells from human embryonic stem cells (hESC) and human induced pluripotent stem cells (hiPS)
    D J Anstee
    Bristol Institute for Transfusion Sciences, NHSBT, Filton, Bristol BS34 7QG, UK
    Transfus Clin Biol 17:104-9. 2010
    ..Studies with human embryonic stem cells have already yielded encouraging results but functional mature biconcave erythrocytes have yet to be generated from these cells...
  12. ncbi request reprint Evidence that the antigens of the Yt blood group system are located on human erythrocyte acetylcholinesterase
    F A Spring
    South Western Regional Blood Transfusion Centre, Bristol, UK
    Blood 80:2136-41. 1992
    ....
  13. ncbi request reprint Use of domain-deletion mutants to locate Lutheran blood group antigens to each of the five immunoglobulin superfamily domains of the Lutheran glycoprotein: elucidation of the molecular basis of the Lu(a)/Lu(b) and the Au(a)/Au(b) polymorphisms
    S F Parsons
    International Blood Group Reference Laboratory, Bristol Institute for Transfusion Sciences, UK
    Blood 89:4219-25. 1997
    ..The Au(a)/Au(b) polymorphism is an A1637 to G substitution in exon 12 encoding a Thr539 (Au(a)) to Ala (Au(b)) change on the G strand of domain 5...
  14. ncbi request reprint Expression of RHD and RHCE gene products using retroviral transduction of K562 cells establishes the molecular basis of Rh blood group antigens
    J S Smythe
    International Blood Group Reference Laboratory, Bristol, UK
    Blood 87:2968-73. 1996
    ..Both c and E antigens were expressed after transduction of K562 cells with a single cDNA, indicating that the c antigen does not arise by alternative splicing (exon skipping) of the product of the RHCE gene, as has been suggested...
  15. doi request reprint Mutations in EKLF/KLF1 form the molecular basis of the rare blood group In(Lu) phenotype
    Belinda K Singleton
    Bristol Institute for Transfusion Sciences BITS, National Blood Service, United Kingdom
    Blood 112:2081-8. 2008
    ..These data provide the first description of inactivating mutations in human EKLF and the first demonstration of a blood group phenotype resulting from mutations in a transcription factor...
  16. ncbi request reprint Normal prion protein trafficking in cultured human erythroblasts
    Rebecca E Griffiths
    Bristol Institute for Transfusion Sciences, National Blood Service, Bristol, UK
    Blood 110:4518-25. 2007
    ....
  17. pmc The Laminin 511/521-binding site on the Lutheran blood group glycoprotein is located at the flexible junction of Ig domains 2 and 3
    Tosti J Mankelow
    Bristol Institute for Transfusion Sciences, National Blood Service, Southmead Road, Bristol, United Kingdom
    Blood 110:3398-406. 2007
    ..These studies imply that structural flexibility of Lutheran may be essential for its interaction with Laminin and present a novel opportunity for the development of therapeutics for sickle cell disease...
  18. pmc Targeted gene deletion demonstrates that the cell adhesion molecule ICAM-4 is critical for erythroblastic island formation
    Gloria Lee
    Life Sciences Division, University of California, Lawrence Berkeley National Laboratory, Bldg 74, 1 Cyclotron Road, Berkeley, CA 94720, USA
    Blood 108:2064-71. 2006
    ....
  19. ncbi request reprint Identification of critical amino-acid residues on the erythroid intercellular adhesion molecule-4 (ICAM-4) mediating adhesion to alpha V integrins
    Tosti J Mankelow
    Bristol Institute for Transfusion Sciences, Southmead Rd, Bristol, BS10 5ND, UK
    Blood 103:1503-8. 2004
    ..Our findings suggest the feasibility of developing selective inhibitors of ICAM-4-integrin adhesion of therapeutic value in these diseases...
  20. ncbi request reprint CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin
    Vanja Karamatic Crew
    Bristol Institute for Transfusion Sciences, Southmead Road, Bristol, BS10 5ND, United Kingdom
    Blood 104:2217-23. 2004
    ....