David I Marks

Summary

Country: UK

Publications

  1. doi request reprint A review of the management of adults with T-cell acute lymphoblastic leukemia
    David I Marks
    Adult BMT Unit, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom
    Blood . 2017
  2. doi request reprint Allogeneic hematopoietic cell transplantation in adult patients with acute lymphoblastic leukemia
    David I Marks
    Adult BMT Unit, University Hospitals Bristol NHS Foundation Trust, Upper Mandlin Street, Bristol BS2 8BJ, UK Electronic address
    Hematol Oncol Clin North Am 28:995-1009. 2014
  3. pmc Unrelated umbilical cord blood transplant for adult acute lymphoblastic leukemia in first and second complete remission: a comparison with allografts from adult unrelated donors
    David I Marks
    Haematologica 99:322-8. 2014
  4. pmc The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated in the UKALLXII/ECOG2993 trial
    David I Marks
    Adult BMT Unit, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
    Haematologica 98:945-52. 2013
  5. doi request reprint Treating the "older" adult with acute lymphoblastic leukemia
    David I Marks
    Haematology and Stem Cell Transplantation, Bristol BMT Unit, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
    Hematology Am Soc Hematol Educ Program 2010:13-20. 2010
  6. pmc Voriconazole versus itraconazole for antifungal prophylaxis following allogeneic haematopoietic stem-cell transplantation
    David I Marks
    University Hospitals Bristol NHS Foundation Trust, Bristol, UK
    Br J Haematol 155:318-27. 2011
  7. pmc The outcome of full-intensity and reduced-intensity conditioning matched sibling or unrelated donor transplantation in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia in first and second complete remission
    David I Marks
    University Hospitals Bristol NHS Trust, Bristol, United Kingdom
    Blood 116:366-74. 2010
  8. pmc T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)
    David I Marks
    Adult Bone Marrow Transplant Unit, University Hospitals Bristol National Health Service Foundation Trust, Bristol, United Kingdom
    Blood 114:5136-45. 2009
  9. pmc Unrelated donor transplants in adults with Philadelphia-negative acute lymphoblastic leukemia in first complete remission
    David I Marks
    Adult Blood and Marrow Transplantation BMT Unit, United Bristol Healthcare Trust, Bristol, United Kingdom
    Blood 112:426-34. 2008
  10. pmc The effect of smoking on allogeneic transplant outcomes
    David I Marks
    University Hospitals Bristol, Bristol, United Kingdom
    Biol Blood Marrow Transplant 15:1277-87. 2009

Detail Information

Publications16

  1. doi request reprint A review of the management of adults with T-cell acute lymphoblastic leukemia
    David I Marks
    Adult BMT Unit, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom
    Blood . 2017
    ..We also describe the current data and potential future options for the use of novel therapies, including nelarabine and gamma-secretase inhibitors, in adult patients with T-cell ALL...
  2. doi request reprint Allogeneic hematopoietic cell transplantation in adult patients with acute lymphoblastic leukemia
    David I Marks
    Adult BMT Unit, University Hospitals Bristol NHS Foundation Trust, Upper Mandlin Street, Bristol BS2 8BJ, UK Electronic address
    Hematol Oncol Clin North Am 28:995-1009. 2014
    ....
  3. pmc Unrelated umbilical cord blood transplant for adult acute lymphoblastic leukemia in first and second complete remission: a comparison with allografts from adult unrelated donors
    David I Marks
    Haematologica 99:322-8. 2014
    ....
  4. pmc The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated in the UKALLXII/ECOG2993 trial
    David I Marks
    Adult BMT Unit, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
    Haematologica 98:945-52. 2013
    ..Prospective trials are required to determine whether poor outcomes in older patients can be improved by reduced-intensity conditioning allografts. NCT00002514 www.clinicaltrials.gov...
  5. doi request reprint Treating the "older" adult with acute lymphoblastic leukemia
    David I Marks
    Haematology and Stem Cell Transplantation, Bristol BMT Unit, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
    Hematology Am Soc Hematol Educ Program 2010:13-20. 2010
    ..A better understanding of the biology of the disease (including gene profiling) may allow individualization of therapy and, in time, targeted therapy...
  6. pmc Voriconazole versus itraconazole for antifungal prophylaxis following allogeneic haematopoietic stem-cell transplantation
    David I Marks
    University Hospitals Bristol NHS Foundation Trust, Bristol, UK
    Br J Haematol 155:318-27. 2011
    ..Voriconazole could be given for significantly longer durations, with less need for other systemic antifungals...
  7. pmc The outcome of full-intensity and reduced-intensity conditioning matched sibling or unrelated donor transplantation in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia in first and second complete remission
    David I Marks
    University Hospitals Bristol NHS Trust, Bristol, United Kingdom
    Blood 116:366-74. 2010
    ..RIC merits further investigation in prospective trials of adult ALL...
  8. pmc T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)
    David I Marks
    Adult Bone Marrow Transplant Unit, University Hospitals Bristol National Health Service Foundation Trust, Bristol, United Kingdom
    Blood 114:5136-45. 2009
    ..001). Only 8 of 123 relapsed patients survive. This study provides a baseline for trials of new drugs, such as nelarabine, and may allow risk-adapted therapy in patients with poor-prognosis T-cell ALL...
  9. pmc Unrelated donor transplants in adults with Philadelphia-negative acute lymphoblastic leukemia in first complete remission
    David I Marks
    Adult Blood and Marrow Transplantation BMT Unit, United Bristol Healthcare Trust, Bristol, United Kingdom
    Blood 112:426-34. 2008
    ..Nearly 40% of adults with ALL in CR1 survive 5 years after URD transplantation. Relapse risks were modest; TRM is the major cause of treatment failure. Selecting closely HLA-matched URD and reducing TRM should improve results...
  10. pmc The effect of smoking on allogeneic transplant outcomes
    David I Marks
    University Hospitals Bristol, Bristol, United Kingdom
    Biol Blood Marrow Transplant 15:1277-87. 2009
    ..A prospective study with detailed demographic, pulmonary function, and quality-of-life data would improve our understanding of this issue...
  11. ncbi request reprint A comparison of cyclophosphamide and total body irradiation with etoposide and total body irradiation as conditioning regimens for patients undergoing sibling allografting for acute lymphoblastic leukemia in first or second complete remission
    David I Marks
    Adult BMT Unit, Bristol Children s Hospital, Bristol, UK
    Biol Blood Marrow Transplant 12:438-53. 2006
    ..We conclude that for HLA-identical sibling allografts for acute lymphoblastic leukemia in CR2, there is an advantage in substituting etoposide for Cy or, when Cy is used, in increasing the TBI dose to > or =13 Gy...
  12. ncbi request reprint Haploidentical stem cell transplantation for children with acute leukaemia
    David I Marks
    BMT Unit, Bristol Children s Hospital, United Bristol Healthcare Trust, Bristol, UK
    Br J Haematol 134:196-201. 2006
    ..None of the nine patients with acute myeloid leukaemia not in remission have survived...
  13. ncbi request reprint The clinical outcome and toxicity of high-dose chemotherapy and autologous stem cell transplantation in patients with myeloma or amyloid and severe renal impairment: a British Society of Blood and Marrow Transplantation study
    Jennifer M Bird
    Bristol Haematology and Oncology Centre, Bristol, UK
    Br J Haematol 134:385-90. 2006
    ..Two of the four patients with amyloidosis have survived. HDT is feasible in these patients and results in 5-year survival in about one-third of patients...
  14. ncbi request reprint Thrombotic thrombocytopenic purpura following stem cell transplantation
    Sarah L Allford
    Adult BMT Unit, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol BS2 8BJ, UK
    Leuk Lymphoma 43:1921-6. 2002
    ..This review summarises the state of knowledge of post-transplant TTP in 2002, addressing all the aforementioned issues and aims to provide the basis for further systematic study of this problematic complication of transplant...
  15. ncbi request reprint Preparations for unrelated donor transplantation
    David I Marks
    Adult BMT Unit, Oncology Day Beds, Bristol Children s Hospital, Bristol, UK
    Leuk Lymphoma 47:403-8. 2006
    ..Many of the recommendations are derived from personal experience; there is a need for more of an evidence base to aid decision-making...
  16. ncbi request reprint The toxicity and efficacy of donor lymphocyte infusions given after reduced-intensity conditioning allogeneic stem cell transplantation
    David I Marks
    Adult BMT Unit, Bristol Children s Hospital, Upper Maudlin Street, Bristol BS2 8BJ, UK
    Blood 100:3108-14. 2002
    ..Further systematic studies are required to determine the efficacy and optimum use of DLI for patients with each disease treated by nonmyeloablative stem cell transplantation...