Handrean Soran

Summary

Affiliation: Manchester Royal Infirmary
Country: UK

Publications

  1. doi request reprint Influence of diabetes on the maintenance of sinus rhythm after a successful direct current cardioversion in patients with atrial fibrillation
    H Soran
    Department of Endocrinology, Central Manchester University Hospitals, Oxford Road, Manchester, M13 9WL, UK
    QJM 101:181-7. 2008
  2. ncbi request reprint The role of the renin angiotensin system blocking in the management of atrial fibrillation
    Handrean Soran
    Central Manchester University Hospitals, Manchester, UK
    Acta Cardiol 63:457-65. 2008
  3. pmc Liver Fat Measured by MR Spectroscopy: Estimate of Imprecision and Relationship with Serum Glycerol, Caeruloplasmin and Non-Esterified Fatty Acids
    Michael France
    Department of Clinical Biochemistry, Cobbett House, Central Manchester Foundation Trust, Oxford Road, Manchester M13 9WL, UK
    Int J Mol Sci 17:. 2016
  4. ncbi request reprint Is there a role for low carbohydrate diets in the management of type 2 diabetes?
    J Worth
    Manchester Diabetes Centre, 193 Hathersage Road, Manchester M13 OJE, UK
    QJM 100:659-63. 2007
  5. doi request reprint Knowledge gaps in the management of familial hypercholesterolaemia. A UK based survey
    Jonathan Schofield
    Cardiovascular Trials Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK Cardiovascular Research Group, Core Technologies Facility, University of Manchester, Manchester, UK
    Atherosclerosis 252:161-5. 2016
  6. doi request reprint Diabetic dyslipidaemia
    Handrean Soran
    aCardiovascular Research Group, School of Biomedicine, University of Manchester bUniversity Department of Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK
    Curr Opin Lipidol 27:313-22. 2016
  7. pmc Diabetes Dyslipidemia
    Jonathan D Schofield
    Faculty of Medical and Human Sciences, Institute of Human Development, University of Manchester, Manchester, UK
    Diabetes Ther 7:203-19. 2016
  8. doi request reprint Unintended positive and negative effects of drugs on lipoproteins
    Tarza J Siahmansur
    aCardiovascular Research Group, School of Medicine, Core Technology Facility 3rd floor, University of Manchester bCardiovascular Trials Unit, Central Manchester and Manchester Children University Hospital NHS Foundation Trust, Manchester, UK
    Curr Opin Lipidol 26:325-37. 2015
  9. doi request reprint How HDL protects LDL against atherogenic modification: paraoxonase 1 and other dramatis personae
    Handrean Soran
    aCardiovascular Research Group, School of Medicine, Core Technology Facility, University of Manchester bCardiovascular Trials Unit, Central Manchester and Manchester Children University Hospital NHS Foundation Trust, Manchester, UK
    Curr Opin Lipidol 26:247-56. 2015
  10. doi request reprint High-density lipoprotein cholesterol raising: does it matter?
    Jonathan D Schofield
    Cardiovascular Trials Unit, Central Manchester University Hospitals, Manchester, UK
    Curr Opin Cardiol 28:464-74. 2013

Collaborators

  • Naveed Younis
  • See Kwok
  • Dexter Canoy
  • Kausik Ray
  • Valentine Charlton-Menys
  • Gordon D O Lowe
  • Geoffrey Gill
  • Jonathan D Schofield
  • Yifen Liu
  • Michael France
  • Rahul Yadav
  • Paul N Durrington
  • Jonathan Schofield
  • Tarza J Siahmansur
  • Rayaz A Malik
  • Prasanna Rao-Balakrishna
  • Basil Ammori
  • Reza Aghamohammadzadeh
  • Angela N Paisley
  • Salam Hama
  • Moulinath Banerjee
  • J Worth
  • Safwaan Adam
  • Steve Williams
  • Jan Hoong Ho
  • Nigel Capps
  • Ruth Eatough
  • Shazli Azmi
  • Lance Sandle
  • Michael W France
  • Tarza Siahmansur
  • Anthony M Heagerty
  • Adam S Greenstein
  • Phil W Pemberton
  • Maria Jeziorska
  • Fardad Soltani
  • Angela J Paisley
  • Basil J Ammori

Detail Information

Publications27

  1. doi request reprint Influence of diabetes on the maintenance of sinus rhythm after a successful direct current cardioversion in patients with atrial fibrillation
    H Soran
    Department of Endocrinology, Central Manchester University Hospitals, Oxford Road, Manchester, M13 9WL, UK
    QJM 101:181-7. 2008
    ..To determine independent risk factors for recurrence of atrial fibrillation (AF) after a successful direct current (DC) cardioversion in patients with and without diabetes...
  2. ncbi request reprint The role of the renin angiotensin system blocking in the management of atrial fibrillation
    Handrean Soran
    Central Manchester University Hospitals, Manchester, UK
    Acta Cardiol 63:457-65. 2008
    ..The objective of the study was to review the current available clinical evidence for the role of renin-angiotensin system (RAS) blockade in the treatment of atrial fibrillation (AF)...
  3. pmc Liver Fat Measured by MR Spectroscopy: Estimate of Imprecision and Relationship with Serum Glycerol, Caeruloplasmin and Non-Esterified Fatty Acids
    Michael France
    Department of Clinical Biochemistry, Cobbett House, Central Manchester Foundation Trust, Oxford Road, Manchester M13 9WL, UK
    Int J Mol Sci 17:. 2016
    ..Reduction of caeruloplasmin with increasing liver fat may be a consequence or a cause of hepatic steatosis. ..
  4. ncbi request reprint Is there a role for low carbohydrate diets in the management of type 2 diabetes?
    J Worth
    Manchester Diabetes Centre, 193 Hathersage Road, Manchester M13 OJE, UK
    QJM 100:659-63. 2007
  5. doi request reprint Knowledge gaps in the management of familial hypercholesterolaemia. A UK based survey
    Jonathan Schofield
    Cardiovascular Trials Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK Cardiovascular Research Group, Core Technologies Facility, University of Manchester, Manchester, UK
    Atherosclerosis 252:161-5. 2016
    ..We conducted a survey to assess knowledge among healthcare professionals involved in the assessment and management of cardiovascular risk and disease in the United Kingdom...
  6. doi request reprint Diabetic dyslipidaemia
    Handrean Soran
    aCardiovascular Research Group, School of Biomedicine, University of Manchester bUniversity Department of Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK
    Curr Opin Lipidol 27:313-22. 2016
    ....
  7. pmc Diabetes Dyslipidemia
    Jonathan D Schofield
    Faculty of Medical and Human Sciences, Institute of Human Development, University of Manchester, Manchester, UK
    Diabetes Ther 7:203-19. 2016
    ....
  8. doi request reprint Unintended positive and negative effects of drugs on lipoproteins
    Tarza J Siahmansur
    aCardiovascular Research Group, School of Medicine, Core Technology Facility 3rd floor, University of Manchester bCardiovascular Trials Unit, Central Manchester and Manchester Children University Hospital NHS Foundation Trust, Manchester, UK
    Curr Opin Lipidol 26:325-37. 2015
    ..Many drugs affect lipid profile and lipoprotein metabolism. We reviewed unintended effects of nonlipid modifying, commonly used medications on lipid profile and lipoprotein metabolism...
  9. doi request reprint How HDL protects LDL against atherogenic modification: paraoxonase 1 and other dramatis personae
    Handrean Soran
    aCardiovascular Research Group, School of Medicine, Core Technology Facility, University of Manchester bCardiovascular Trials Unit, Central Manchester and Manchester Children University Hospital NHS Foundation Trust, Manchester, UK
    Curr Opin Lipidol 26:247-56. 2015
    ..To summarize the current evidence about how HDL impedes the oxidative and glycative atherogenic modification of LDL...
  10. doi request reprint High-density lipoprotein cholesterol raising: does it matter?
    Jonathan D Schofield
    Cardiovascular Trials Unit, Central Manchester University Hospitals, Manchester, UK
    Curr Opin Cardiol 28:464-74. 2013
    ....
  11. pmc Effects of bariatric surgery on human small artery function: evidence for reduction in perivascular adipocyte inflammation, and the restoration of normal anticontractile activity despite persistent obesity
    Reza Aghamohammadzadeh
    Cardiovascular Research Group, University of Manchester, Manchester, United Kingdom
    J Am Coll Cardiol 62:128-35. 2013
    ..The aim of this study was to investigate the effects of bariatric surgery on small artery function and the mechanisms underlying this...
  12. doi request reprint Small dense LDL is more susceptible to glycation than more buoyant LDL in Type 2 diabetes
    Nahla N Younis
    Cardiovascular Research Group, School of Biomedicine, University of Manchester, Manchester, UK
    Clin Sci (Lond) 124:343-9. 2013
    ..In conclusion, greater susceptibility of SD-LDL to glycation is likely to contribute to the raised levels of circulating glyc-apoB in diabetes. Statins are associated with lower levels of both SD-LDL and glyc-apoB...
  13. doi request reprint HDL functionality
    Handrean Soran
    University Department of Medicine, Central Manchester and Manchester Children University Hospital NHS Foundation Trust, School of Biomedicine, University of Manchester, Manchester, UK
    Curr Opin Lipidol 23:353-66. 2012
    ..The purpose of this review is to summarize HDL functionality, its relevance to atherosclerosis and factors affecting HDL functions...
  14. doi request reprint Cholesterol, not just cardiovascular risk, is important in deciding who should receive statin treatment
    Handrean Soran
    Cardiovascular Research Group, School of Biomedicine, University of Manchester, Core Technology Facility 3rd floor, 46 Grafton Street, Manchester M13 9NT, UK Cardiovascular Trials Unit, University Department of Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK
    Eur Heart J 36:2975-83. 2015
    ....
  15. doi request reprint A review of paradoxical HDL-C responses to fenofibrate, illustrated by a case report
    Jonathan D Schofield
    Cardiovascular Trials Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK Cardiovascular Research Group, Core Technology Facility, University of Manchester, Manchester, UK
    J Clin Lipidol 8:455-9. 2014
    ..This review considers possible mechanisms for this effect, illustrated by a patient with an observed reduction in HDL-C of 88% after introduction of fenofibrate...
  16. doi request reprint The importance of considering LDL cholesterol response as well as cardiovascular risk in deciding who can benefit from statin therapy
    Handrean Soran
    aCardiovascular Research Group, School of Biomedicine, University of Manchester, bCardiovascular Trials Unit, University Department of Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK
    Curr Opin Lipidol 25:239-46. 2014
    ..We question whether this is an effective strategy unless the LDL-cholesterol (LDL-C) response is also considered...
  17. doi request reprint Lipoprotein (a): gene genie
    Paul N Durrington
    aCardiovascular Research Group, School of Biomedicine, University of Manchester bCardiovascular Trials Unit, University Department of Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK
    Curr Opin Lipidol 25:289-96. 2014
    ..We review barriers to progress, and discuss areas of controversy which are important to future research...
  18. doi request reprint Body fat distribution in relation to smoking and exogenous hormones in British women
    See Kwok
    School of Biomedicine, University of Manchester, Manchester, UK
    Clin Endocrinol (Oxf) 77:828-33. 2012
    ..We examined the interrelation between smoking, exogenous hormones and fat distribution in premenopausal and postmenopausal women...
  19. doi request reprint Dapagliflozin: a review on efficacy, clinical effectiveness and safety
    Angela N Paisley
    Salford Royal NHS Foundation Trust, Department of Endocrinology and Diabetes, Stott Lane, Salford, Manchester, M6 8HD, UK
    Expert Opin Investig Drugs 22:131-40. 2013
    ..By blocking glucose reabsorption in the kidney they lead to an increase in urinary glucose excretion with reduction in plasma glucose levels...
  20. doi request reprint Extended-release niacin with laropiprant : a review on efficacy, clinical effectiveness and safety
    Rahul Yadav
    University of Manchester, School of Biomedicine, Cardiovascular Research Group, Core Technology Facility, 46, Grafton Street, Manchester, UK
    Expert Opin Pharmacother 13:1345-62. 2012
    ..Interest in niacin has re-emerged because of its HDL-C raising effects. The flushing associated with niacin which has previously affected patient compliance can now be significantly blocked with laropiprant (LRPT)...
  21. doi request reprint Vildagliptin in clinical practice: a review of literature
    Moulinath Banerjee
    Central Manchester University Hospitals Foundation Trust, Department of Medicine, Manchester, M13 9WL, UK
    Expert Opin Pharmacother 10:2745-57. 2009
    ..This review undertakes to examine the clinical studies published to date, with the aim of evaluating the position of vildagliptin among the drugs that are now available to treat this common dysmetabolic state...
  22. doi request reprint Aspirin therapy and primary prevention of cardiovascular disease in diabetes mellitus
    Naveed Younis
    Department of Diabetes and Endocrinology, University Hospital South Manchester NHS Foundation Trust, Southmoor Road, Wythenshawe, Manchester, UK
    Diabetes Obes Metab 11:997-1000. 2009
    ..This article reviews the results of two recently published large randomized clinical trials that have looked at primary prevention of cardiovascular events using aspirin in patients with DM...
  23. ncbi request reprint Insulin glargine: a new basal insulin analogue
    N Younis
    Department of Endocrinology, Arrowe Park Hospital, Wirral, UK
    QJM 95:757-61. 2002
  24. ncbi request reprint The prevention of type 2 diabetes mellitus: recent advances
    N Younis
    Department of Diabetes and Endocrinology, University Hospital Aintree, Liverpool, UK
    QJM 97:451-5. 2004
    ..Other pharmacological interventions are currently being examined in large prospective studies. It is likely that one or a combination of these approaches could make diabetes prevention a reality in the near future...
  25. ncbi request reprint The benefits of insulin therapy following acute myocardial infarction revisited
    H Soran
    Specialist Registrar in Endocrinology and Diabetes, Department of Diabetes and Endocrinology, South Manchester University Hospital, Manchester
    QJM 99:635-7. 2006
  26. ncbi request reprint A case of haemangiopericytoma-associated hypoglycaemia: Beneficial effect of treatment with radiotherapy
    H Soran
    Department of Medicine, Wirral Hospital NHS Trust, Wirral, Cheshire, UK
    Int J Clin Pract 60:1319-22. 2006
    ..Clinically and biochemically, radiotherapy was more effective than GH therapy...
  27. ncbi request reprint Inflammatory pseudotumour of the liver associated with diabetes mellitus
    N Younis
    Department of Diabetes and Endocrinology, Royal Liverpool University Hospital, UK
    Int J Clin Pract 55:717-9. 2001
    ..The clinical outcome was good and both patients had an uneventful recovery. We believe these to be the first two cases of inflammatory liver pseudotumours to be described in patients with diabetes mellitus...