Selina Wray

Summary

Affiliation: King's College London
Country: UK

Publications

  1. doi request reprint Direct analysis of tau from PSP brain identifies new phosphorylation sites and a major fragment of N-terminally cleaved tau containing four microtubule-binding repeats
    Selina Wray
    MRC Centre for Neurodegeneration Research, King s College London, Institute of Psychiatry, London, UK
    J Neurochem 105:2343-52. 2008
  2. doi request reprint Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases
    C Hugh Reynolds
    The MRC Centre for Neurodegeneration Research, King s College London, Institute of Psychiatry, London, UK
    J Biol Chem 283:18177-86. 2008
  3. ncbi request reprint Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis
    Diane P Hanger
    MRC Centre for Neurodegeneration Research, Department of Neuroscience, King s College London, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    J Biol Chem 282:23645-54. 2007
  4. doi request reprint Tau cleavage and tau aggregation in neurodegenerative disease
    Diane P Hanger
    Department of Neuroscience, King s College London, Institute of Psychiatry, MRC Centre for Neurodegeneration Research, De Crespigny Park, London SE5 8AF, UK
    Biochem Soc Trans 38:1016-20. 2010
  5. pmc Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer's disease
    Joe Atherton
    Institute of Psychiatry, Department of Neuroscience, King s College London, London, SE5 8AF, UK
    Aging Cell 13:49-59. 2014
  6. pmc The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy
    Victoria S Burchell
    Department of Molecular Neuroscience, University College London Institute of Neurology, London, UK
    Nat Neurosci 16:1257-65. 2013
  7. pmc Using human induced pluripotent stem cells to model cerebellar disease: Hope and hype
    Sarah Wiethoff
    a National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, London, UK
    J Neurogenet 29:95-102. 2015
  8. doi request reprint Comprehensive analysis of the TRPV4 gene in a large series of inherited neuropathies and controls
    Katherine A Fawcett
    MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, UK
    J Neurol Neurosurg Psychiatry 83:1204-9. 2012

Collaborators

Detail Information

Publications8

  1. doi request reprint Direct analysis of tau from PSP brain identifies new phosphorylation sites and a major fragment of N-terminally cleaved tau containing four microtubule-binding repeats
    Selina Wray
    MRC Centre for Neurodegeneration Research, King s College London, Institute of Psychiatry, London, UK
    J Neurochem 105:2343-52. 2008
    ..Our findings suggest the aggregatory characteristics of PSP-tau differ from those of insoluble tau in Alzheimer's disease brain and this might be related to the presence of a C-terminal cleavage product of tau...
  2. doi request reprint Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases
    C Hugh Reynolds
    The MRC Centre for Neurodegeneration Research, King s College London, Institute of Psychiatry, London, UK
    J Biol Chem 283:18177-86. 2008
    ....
  3. ncbi request reprint Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis
    Diane P Hanger
    MRC Centre for Neurodegeneration Research, Department of Neuroscience, King s College London, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    J Biol Chem 282:23645-54. 2007
    ....
  4. doi request reprint Tau cleavage and tau aggregation in neurodegenerative disease
    Diane P Hanger
    Department of Neuroscience, King s College London, Institute of Psychiatry, MRC Centre for Neurodegeneration Research, De Crespigny Park, London SE5 8AF, UK
    Biochem Soc Trans 38:1016-20. 2010
    ..We also discuss the evidence for the involvement of proteases in the generation of tau pathology in neurodegenerative disease, since these enzymes warrant further investigation as potential therapeutic targets in the tauopathies...
  5. pmc Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer's disease
    Joe Atherton
    Institute of Psychiatry, Department of Neuroscience, King s College London, London, SE5 8AF, UK
    Aging Cell 13:49-59. 2014
    ....
  6. pmc The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy
    Victoria S Burchell
    Department of Molecular Neuroscience, University College London Institute of Neurology, London, UK
    Nat Neurosci 16:1257-65. 2013
    ..Parkinson's disease-causing mutations in Fbxo7 interfered with this process, emphasizing the importance of mitochondrial dysfunction in Parkinson's disease pathogenesis. ..
  7. pmc Using human induced pluripotent stem cells to model cerebellar disease: Hope and hype
    Sarah Wiethoff
    a National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, London, UK
    J Neurogenet 29:95-102. 2015
    ..This in turn will permit a greater understanding of cerebellar pathophysiology to inform mechanistically rationalised therapies, which are desperately needed in this field. ..
  8. doi request reprint Comprehensive analysis of the TRPV4 gene in a large series of inherited neuropathies and controls
    Katherine A Fawcett
    MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, UK
    J Neurol Neurosurg Psychiatry 83:1204-9. 2012
    ..TRPV4 mutations have been identified in Charcot-Marie-Tooth type 2 (CMT2), scapuloperoneal spinal muscular atrophy and distal hereditary motor neuropathy (dHMN)...