Affiliation: King's College London
- Episodic memory dysfunction in individuals at high-risk of psychosis: a systematic review of neuropsychological and neurofunctional studiesIsabel Valli
Department of Psychosis Studies, Institute of Psychiatry, King s College London, De Crespigny Park, SE5 8AF, London, UK
Curr Pharm Des 18:443-58. 2012....
- Altered medial temporal activation related to local glutamate levels in subjects with prodromal signs of psychosisIsabel Valli
Department of Psychosis Studies, King s College London, London, United Kingdom
Biol Psychiatry 69:97-9. 2011..However, although animal models of psychosis suggest that these two abnormalities are interrelated, their relationship in humans has yet to be investigated...
- Abnormal relationship between medial temporal lobe and subcortical dopamine function in people with an ultra high risk for psychosisPaul Allen
Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, UK
Schizophr Bull 38:1040-9. 2012....
- Altered prefrontal and hippocampal function during verbal encoding and recognition in people with prodromal symptoms of psychosisPaul Allen
Section of Neuroimaging, Division of Psychological Medicine, Institute of Psychiatry, London, UK
Schizophr Bull 37:746-56. 2011..These neurofunctional differences were associated with diminished recognition performance and may reflect the greatly increased risk of psychosis associated with the ARMS...
- Transition to psychosis associated with prefrontal and subcortical dysfunction in ultra high-risk individualsPaul Allen
Department of Psychosis Studies, Institute of Psychiatry, King s College, London, UK
Schizophr Bull 38:1268-76. 2012..We investigated whether functional magnetic resonance imaging (fMRI) in conjunction with a phonological fluency task at presentation could distinguish subjects who subsequently developed psychosis from those who did not...
- Abnormal frontostriatal interactions in people with prodromal signs of psychosis: a multimodal imaging studyPaolo Fusar-Poli
Psychosis Clinical Academic Group PO67, Institute of Psychiatry, De Crespigny Park, London SE58AF, England
Arch Gen Psychiatry 67:683-91. 2010..Alterations in dopaminergic neurotransmission and function of the prefrontal cortex are thought to be central to the pathophysiology of schizophrenia, but the relationship between these factors in the development of psychosis is unclear...
- Neuroanatomical abnormalities that predate the onset of psychosis: a multicenter studyAndrea Mechelli
Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, United Kingdom
Arch Gen Psychiatry 68:489-95. 2011..However, the samples examined to date have been small, and the findings have been inconsistent...
- Dopamine synthesis capacity before onset of psychosis: a prospective [18F]-DOPA PET imaging studyOliver D Howes
Hammersmith Hospital, London, UK
Am J Psychiatry 168:1311-7. 2011..The authors addressed this issue by measuring dopamine synthesis capacity in individuals at ultra-high risk of psychosis and then following them to determine their clinical outcome...
- Effect of BDNF val(66)met polymorphism on declarative memory and its neural substrate: a meta-analysisJoseph P Kambeitz
Department of Psychosis Studies, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
Neurosci Biobehav Rev 36:2165-77. 2012..These results underscore the role of BDNF in moderating variability between individuals in human memory performance and in mediating some of the neurocognitive impairments underlying neuropsychiatric disorders...
- Elevated striatal dopamine function linked to prodromal signs of schizophreniaOliver D Howes
Section of Neuroimaging, Institute of Psychiatry, King s College London, England
Arch Gen Psychiatry 66:13-20. 2009....
- Glutamate dysfunction in people with prodromal symptoms of psychosis: relationship to gray matter volumeJames M Stone
Institute of Psychiatry, King s College London, University College London, United Kingdom
Biol Psychiatry 66:533-9. 2009..Here we determine whether changes in brain glutamate are present in subjects at ultra high risk of developing psychosis and whether these changes are related to reductions in cortical gray matter volume...