Affiliation: King's College London
- Bile composition in Alagille Syndrome and PFIC patients having Partial External Biliary DiversionKaran M Emerick
Children s Memorial Hospital, Chicago, IL, USA
BMC Gastroenterol 8:47. 2008..PEBD can reduce disease progression, and examining the alterations in biliary lipid composition may be a prognostic factor for outcome...
- Genetic defects in hepatocanalicular transportR Thompson
Department of Child Health Guy s, King s and St Thomas School of Medicine, King s College Hospital, London, United Kingdom
Semin Liver Dis 20:365-72. 2000..In addition, a secondary defect in bile acid transport has been identified that appears to be due to an abnormality in plasma membrane aminophospholipid distribution...
- BSEP: function and role in progressive familial intrahepatic cholestasisR Thompson
Department of Child Health, Guy s, King s, and St Thomas School of Medicine, King s College Hospital, London, UK
Semin Liver Dis 21:545-50. 2001..Understanding the structure and function of BSEP has improved our understanding of the mechanisms underlying bile secretion. Determining genotype/phenotype relationships in patients with mutations in this gene are currently ongoing...
- Inherited disorders of transport in the liverR Thompson
Department of Child Health, Guy s, King s and St Thomas School of Medicine, King s College Hospital, London, SE5 9RS, UK richard j
Curr Opin Genet Dev 10:310-3. 2000..The physiological roles of many of these transporters have been well characterised previously but have, until now, been resistant to molecular cloning...