Frank A Post
Affiliation: King's College London
- Multi-drug-resistant tuberculosis in HIV positive patients in Eastern EuropeFrank A Post
King s College London School of Medicine, London SE5 9RJ, UK Electronic address
J Infect 68:259-63. 2014..Implementation of WHO guidelines, rapid TB diagnostics and TB drug susceptibility testing for all patients remain a priority in this region. ..
- Outcome of AIDS-associated cryptococcal meningitis initially treated with 200 mg/day or 400 mg/day of fluconazoleC F Schaars
Division of Infectious Diseases, University of Cape Town, Cape Town, South Africa
BMC Infect Dis 6:118. 2006..In 2001 donated fluconazole became available, allowing us to use standard doses (400 mg daily initially). Antiretroviral therapy was not available during the study period...
- Predictors of renal outcome in HIV-associated nephropathyFrank A Post
Academic Dept of HIV GUM, King s College London School of Medicine at Guy s, King s College, London, United Kingdom
Clin Infect Dis 46:1282-9. 2008..This study was performed to study the epidemiology of HIVAN in a predominantly black African population and the impact of highly active antiretroviral therapy and other factors on the development of end-stage renal disease...
- Recent developments in HIV and the kidneyFrank A Post
Department of HIV GU Medicine, King s College London, London, UK
Curr Opin Infect Dis 22:43-8. 2009..This has resulted in heightened interest in noninfectious comorbidities including kidney disease. This review focuses on recent progress in our understanding of the clinical epidemiology of HIV-associated kidney disease...
- Total protein, albumin and low-molecular-weight protein excretion in HIV-positive patientsLucy J Campbell
Academic Department of Renal Sciences, King s College London, London, United Kingdom
BMC Nephrol 13:85. 2012..We analysed 3 LMWP as well as protein and albumin in the urine of a sample of HIV positive patients...
- Randomized comparison of renal effects, efficacy, and safety with once-daily abacavir/lamivudine versus tenofovir/emtricitabine, administered with efavirenz, in antiretroviral-naive, HIV-1-infected adults: 48-week results from the ASSERT studyFrank A Post
King s College London, London, United Kingdom
J Acquir Immune Defic Syndr 55:49-57. 2010..Abacavir/lamivudine and tenofovir/emtricitabine fixed-dose combinations are commonly used first-line antiretroviral therapies, yet few studies have comprehensively compared their safety profiles...
- Baseline kidney function as predictor of mortality and kidney disease progression in HIV-positive patientsFowzia Ibrahim
King s College London, United Kingdom
Am J Kidney Dis 60:539-47. 2012..Decreased kidney function at baseline may identify human immunodeficiency virus (HIV)-positive patients at increased risk of death and kidney disease progression...
- HIV care and the incidence of acute renal failureJennifer Roe
Academic Departments of 1HIV GU Medicine and 2Renal Medicine, King College London, London, United Kingdom
Clin Infect Dis 47:242-9. 2008..The clinical epidemiology of acute renal failure (ARF) in human immunodeficiency virus (HIV)-infected patients remains poorly defined...
- Immunodeficiency and renal impairment are risk factors for HIV-associated acute renal failureFowzia Ibrahim
King s College London, UK
AIDS 24:2239-44. 2010..To identify risk factors for acute renal failure (ARF) in HIV-infected patients...
- Comparison of CKD-EPI and MDRD to estimate baseline renal function in HIV-positive patientsFowzia Ibrahim
Department of Renal Sciences, King s College London, London, UK
Nephrol Dial Transplant 27:2291-7. 2012..It is unknown whether Chronic Kidney Disease Epidemiological Collaboration (CKD-EPI) or Modification of Diet in Renal Disease (MDRD) provide better estimates of glomerular filtration rate (GFR) in this population...
- Impact of Tacrolimus Compared With Cyclosporin on the Incidence of Acute Allograft Rejection in Human Immunodeficiency Virus-Positive Kidney Transplant RecipientsEsther Gathogo
1 Department of Renal Sciences, King s College London, London, United Kingdom 2 Department of Renal Medicine, Royal Free London NHS Foundation Trust, London, United Kingdom 3 Department of HIV Medicine and Infectious Diseases, Royal Free London NHS Foundation Trust, London, United Kingdom 4 Department of Renal Medicine, Imperial College Healthcare NHS Trust, London, United Kingdom 5 Department of HIV Medicine, Chelsea and Westminster Hospital, London, United Kingdom 6 Department of Renal Medicine, Guy s and St Thomas NHS Foundation Trust, London, United Kingdom 7 Institute of Pharmaceutical Science, King s College London, London, United Kingdom 8 Department of HIV Research, King s College Hospital NHS Foundation Trust, London, United Kingdom
Transplantation 100:871-8. 2016..We examined factors associated with AR in the first year after KT, with particular emphasis on the choice of calcineurin inhibitor (CNI) immunosuppressive therapy...
- Late HIV diagnosis is a major risk factor for intensive care unit admission in HIV-positive patients: a single centre observational cohort studyJulia Shrosbree
King s College Hospital, Bessemer Road, London, UK
BMC Infect Dis 13:23. 2013..While the characteristics of patients requiring ICU admission have been described previously, these studies did not include information on the denominator population from which these cases arose...
- Risk factors and outcomes for late presentation for HIV-positive persons in Europe: results from the Collaboration of Observational HIV Epidemiological Research Europe Study (COHERE)Amanda Mocroft
Department of Infection and Population Health, University College London, London, United Kingdom
PLoS Med 10:e1001510. 2013..Few studies have monitored late presentation (LP) of HIV infection over the European continent, including Eastern Europe. Study objectives were to explore the impact of LP on AIDS and mortality...
- Clinical epidemiology of HIV-associated end-stage renal failure in the UKLoveleen Bansi
University College London Medical School, London, UK
AIDS 23:2517-21. 2009..To describe the clinical epidemiology of HIV-associated end-stage renal failure (HIV/ESRF) from 1998 to 2007 in the United Kingdom...
- Improved kidney function in patients who switch their protease inhibitor from atazanavir or lopinavir to darunavirSophie Jose
aResearch Department of Infection and Population Health, University College LondonbChelsea and Westminster NHS Foundation Trust, LondoncSouth Tees Hospitals NHS Foundation Trust, MiddlesbroughdHIV I Base, LondoneBrighton and Sussex University Hospitals, BrightonfKings College Hospital NHS Foundation Trust, London, UK
AIDS 31:485-492. 2017..We examined kidney function in patients who switched their protease inhibitor from ATV or LPV to DRV...
- HIV and the kidneyFrank A Post
Academic Department of HIV Genitourinary Medicine, King s College London, London SE5 9RJ
Br J Hosp Med (Lond) 69:137-40. 2008..Antiretroviral therapy has dramatically improved the life expectancy of HIV-infected patients with end-stage renal disease. Renal replacement therapy, including kidney transplantation, should be offered to HIV-positive patients...
- End-stage kidney disease and kidney transplantation in HIV-positive patients: an observational cohort studyEsther Gathogo
Department of Renal Sciences, King s College London, London, United Kingdom Research Department of Infection and Population Health, University College London, London, United Kingdom West London Centre for Sexual Health, Chelsea and Westminster Hospital NHS Foundation Trust, London, United Kingdom Imperial College Kidney and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom UCL Centre for Nephrology, Royal Free Hospital NHS Foundation Trust, London, United Kingdom Department of Infectious Diseases, The Lothian University Hospitals NHS Trust, Edinburgh, United Kingdom Department of Sexual Health and HIV, Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom and Department of Sexual Health and HIV, King s College Hospital NHS Foundation Trust, London, United Kingdom
J Acquir Immune Defic Syndr 67:177-80. 2014..Survival was similar for KT recipients and those awaiting KT (85% and 89% at 5 years, respectively; P = 0.53). Our results endorse the use of KT to manage ESKD in HIV-positive patients...
- Low frequency of genotypic resistance in HIV-1-infected patients failing an atazanavir-containing regimen: a clinical cohort studyDavid I Dolling
Medical Research Council Clinical Trials Unit, London, UK
J Antimicrob Chemother 68:2339-43. 2013..To determine protease mutations that develop at viral failure for protease inhibitor (PI)-naive patients on a regimen containing the PI atazanavir...
- Kidney transplantation in HIV-positive adults: the UK experienceEsther N Gathogo
King s College London, London, UK
Int J STD AIDS 25:57-66. 2014..Our study corroborates the feasibility of kidney transplantation in HIV-positive patients. The high rates of acute rejection suggest that the optimal immune suppression strategy in this population remains to be refined. ..
- HIV-associated kidney disease in the context of an aging populationClaire Naftalin
Department of HIV Sexual Health, King s College Hospital, London SE5 9RS, UK
Sex Health 8:485-92. 2011..Consequently, HIV care increasingly needs to incorporate strategies to detect and manage these non-infectious co-morbidities...
- Renal impairment is associated with coronary heart disease in HIV-positive menLucy J Campbell
School of Medicine, King s College, London, UK
HIV Clin Trials 13:343-9. 2012..Chronic kidney disease is a risk factor for coronary heart disease (CHD). The association between renal impairment and CHD in HIV-positive patients remains poorly described...
- Antiretrovirals and the kidney in current clinical practice: renal pharmacokinetics, alterations of renal function and renal toxicityJean C Yombi
aAIDS Reference Centre, St Luc University Hospital, Catholic University of Louvain, Brussels, Belgium bSt Stephen s AIDS Trust, Chelsea and Westminster Hospital, London cUniversity of Liverpool, Liverpool dImperial College Healthcare NHS Trust eKing s College London School of Medicine, London, UK
AIDS 28:621-32. 2014..This review explores the effects of antiretroviral therapy on the kidney and offers an understanding of mechanisms that lead to apparent and real changes in renal function...
- Efavirenz is associated with severe vitamin D deficiency and increased alkaline phosphataseTanya Welz
Department of HIV Genitourinary Medicine, King s College Hospital, London, UK
AIDS 24:1923-8. 2010....
- Biomarkers of impaired renal functionFrank A Post
King s College London School of Medicine, London, UK
Curr Opin HIV AIDS 5:524-30. 2010..Several biomarkers are available for monitoring renal function, although no consensus exists on how best to apply these tools in HIV infection. This review describes recent findings for the more common renal biomarkers...
- Clinical characteristics and outcomes of HIV-associated immune complex kidney diseaseJohn W Booth
Royal Free Hospital NHS Foundation Trust and University College London, London, UK
Nephrol Dial Transplant 31:2099-2107. 2016..Key questions remain unanswered, including the role of HIV infection and replication in disease development and the efficacy of antiretroviral therapy (ART) in the prevention and treatment of disease...
- Defining cognitive impairment in people-living-with-HIV: the POPPY studyDavide De Francesco
Research Department of Infection and Population Health, UCL Royal Free Campus, London, UK
BMC Infect Dis 16:617. 2016..Agreement between diagnostic criteria of CI, the optimal definition to use, and associations with patient-reported cognitive symptoms have not been fully investigated...
- Switching to Tenofovir Alafenamide, Coformulated With Elvitegravir, Cobicistat, and Emtricitabine, in HIV-Infected Patients With Renal Impairment: 48-Week Results From a Single-Arm, Multicenter, Open-Label Phase 3 StudyAnton Pozniak
Chelsea and Westminster Hospital NHS Foundation Trust, London, United Kingdom Department of Medicine, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain Therapeutic Concepts, Houston, TX Department of Medicine, Indiana University School of Medicine, Indianapolis, IN King s College Hospital NHS Foundation Trust, London, United Kingdom Holdsworth House Medical Practice, Sydney, Australia HIV NAT, Thai Red Cross AIDS Research Centre and Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand Gordon Crofoot Research, Houston, TX Be Well Medical Center, Berkley, MI Department of Medicine, National Jewish Health, Denver, CO Midway Research Center, Ft Pierce, FL Department of Medicine, Khon Kaen University, Thailand and Gilead Sciences, Foster City, CA
J Acquir Immune Defic Syndr 71:530-7. 2016....
- Antiretroviral therapy in advanced HIV-1 infectionFrank A Post
Department of HIV GUM, King s College, London
J Int Assoc Physicians AIDS Care (Chic) 4:8-10, 13-5. 2005....
- Effects of vitamin D deficiency and combination antiretroviral therapy on bone in HIV-positive patientsKathryn Childs
aKing s College Hospital bBrighton and Sussex Medical School cKing s College London School of Medicine, London, UK
AIDS 26:253-62. 2012..The objective of this review was to evaluate the evidence for such a strategy...