Ali Nokhodchi

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Development and evaluation of buccoadhesive propranolol hydrochloride tablet formulations: effect of fillers
    Jafar Akbari
    Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran Sari Medical Sciences University, Sari, Iran
    Farmaco 59:155-61. 2004
  2. ncbi request reprint In situ cross-linking of sodium alginate with calcium and aluminum ions to sustain the release of theophylline from polymeric matrices
    Ali Nokhodchi
    Pharmacy Department, Kings College London, 150 Stamford Street, Franklin Wilkins Building, London SE1 9NN, UK
    Farmaco 59:999-1004. 2004
  3. ncbi request reprint The effect of type and concentration of vehicles on the dissolution rate of a poorly soluble drug (indomethacin) from liquisolid compacts
    Ali Nokhodchi
    Department of Pharmacy, School of Health and Life Sciences, King s College London, London, United Kingdom
    J Pharm Pharm Sci 8:18-25. 2005
  4. doi request reprint Control of encapsulation efficiency in polymeric microparticle system of tolmetin
    Mitra Jelvehgari
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Pharm Dev Technol 15:71-9. 2010
  5. ncbi request reprint Mechanistic evaluation of the effect of thermal-treating on Eudragit RS matrices
    Shirzad Azarmi
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    Farmaco 60:925-30. 2005
  6. doi request reprint Micromeritics and release behaviours of cellulose acetate butyrate microspheres containing theophylline prepared by emulsion solvent evaporation and emulsion non-solvent addition method
    Mitra Jelvehgari
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Arch Pharm Res 32:1019-28. 2009
  7. ncbi request reprint Liquisolid technique for dissolution rate enhancement of a high dose water-insoluble drug (carbamazepine)
    Yousef Javadzadeh
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Iran
    Int J Pharm 341:26-34. 2007
  8. doi request reprint In vitro and in vivo evaluation of insulin microspheres containing protease inhibitor
    Mitra Jelvehgari
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Arzneimittelforschung 61:14-22. 2011
  9. ncbi request reprint Propranolol hydrochloride osmotic capsule with controlled onset of release
    Mohammad Barzegar-Jalali
    Department of Pharmaceutics, School of Pharmacy, and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Drug Deliv 14:461-8. 2007
  10. ncbi request reprint Preparation and characterization of solid dispersions of piroxicam with hydrophilic carriers
    Hadi Valizadeh
    Department of Pharmaceutics, Tabriz University of Medical Sciences, Tabriz, Iran
    Drug Dev Ind Pharm 33:45-56. 2007

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Development and evaluation of buccoadhesive propranolol hydrochloride tablet formulations: effect of fillers
    Jafar Akbari
    Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran Sari Medical Sciences University, Sari, Iran
    Farmaco 59:155-61. 2004
    ..The values of n in this study were calculated to be between 0.461 and 0.619, indicating both diffusional release and erosional mechanism...
  2. ncbi request reprint In situ cross-linking of sodium alginate with calcium and aluminum ions to sustain the release of theophylline from polymeric matrices
    Ali Nokhodchi
    Pharmacy Department, Kings College London, 150 Stamford Street, Franklin Wilkins Building, London SE1 9NN, UK
    Farmaco 59:999-1004. 2004
    ....
  3. ncbi request reprint The effect of type and concentration of vehicles on the dissolution rate of a poorly soluble drug (indomethacin) from liquisolid compacts
    Ali Nokhodchi
    Department of Pharmacy, School of Health and Life Sciences, King s College London, London, United Kingdom
    J Pharm Pharm Sci 8:18-25. 2005
    ..The object of the present study is to increase dissolution rate of indomethacin using liquisolid compacts...
  4. doi request reprint Control of encapsulation efficiency in polymeric microparticle system of tolmetin
    Mitra Jelvehgari
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Pharm Dev Technol 15:71-9. 2010
    ..In order to prevent many unfavorable events such as pore formation, drug loss, and drug migration that occur while the dispersed phase is in the semi-solid state, it is important to understand and optimize these variables...
  5. ncbi request reprint Mechanistic evaluation of the effect of thermal-treating on Eudragit RS matrices
    Shirzad Azarmi
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    Farmaco 60:925-30. 2005
    ..FTIR results did not show any drug-polymer interaction due to heat-treatment. DSC and PXD studies ruled out the occurrence of solid solution and polymorphic change of the drug...
  6. doi request reprint Micromeritics and release behaviours of cellulose acetate butyrate microspheres containing theophylline prepared by emulsion solvent evaporation and emulsion non-solvent addition method
    Mitra Jelvehgari
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Arch Pharm Res 32:1019-28. 2009
    ..No major chemical interaction between the drug and polymer was reported during the encapsulation process...
  7. ncbi request reprint Liquisolid technique for dissolution rate enhancement of a high dose water-insoluble drug (carbamazepine)
    Yousef Javadzadeh
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Iran
    Int J Pharm 341:26-34. 2007
    ..The results of DSC and X-ray crystallography did not show any changes in crystallinity of the drug and interaction between carbamazepine and exipients during the process...
  8. doi request reprint In vitro and in vivo evaluation of insulin microspheres containing protease inhibitor
    Mitra Jelvehgari
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Arzneimittelforschung 61:14-22. 2011
    ....
  9. ncbi request reprint Propranolol hydrochloride osmotic capsule with controlled onset of release
    Mohammad Barzegar-Jalali
    Department of Pharmaceutics, School of Pharmacy, and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Drug Deliv 14:461-8. 2007
    ..2, 4.8, 5.9, 5.5, 7.5, 5.0, 7.8 and 10.5 hr could be of use for either chronotherapeutic purposes in protection of patients against heart attacks and strokes during early morning hours or reducing daily frequency of dosage...
  10. ncbi request reprint Preparation and characterization of solid dispersions of piroxicam with hydrophilic carriers
    Hadi Valizadeh
    Department of Pharmaceutics, Tabriz University of Medical Sciences, Tabriz, Iran
    Drug Dev Ind Pharm 33:45-56. 2007
    ..Data from the X-ray diffraction and FT-IR spectroscopy showed that piroxicam was amorphous in the solid dispersions prepared with dextrin and Eudragit E100...
  11. doi request reprint Development of azithromycin-PLGA nanoparticles: physicochemical characterization and antibacterial effect against Salmonella typhi
    Ghobad Mohammadi
    Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Colloids Surf B Biointerfaces 80:34-9. 2010
    ..In conclusion, the azithromycin nanoparticle preparations showed appropriate physicochemical and improved antimicrobial properties which can be useful for oral administration...
  12. ncbi request reprint The influence of thermal treatment on the release behavior of diclofenac sodium from acrylic matrices
    Shirzad Azarmi
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Pharm Dev Technol 10:233-9. 2005
    ..These structural changes in the tablet compacts resulted in a matrix structure that decreased the release rate of the diclofenac sodium from Eudragit matrices...
  13. ncbi request reprint A correlative model to predict in vivo AUC for nanosystem drug delivery with release rate-limited absorption
    Mohammad Barzegar-Jalali
    Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran
    J Pharm Pharm Sci 15:583-91. 2012
    ..Thus, in vitro drug release is of paramount importance in gaining insight for the systems performance in vivo...
  14. doi request reprint Physicochemical and anti-bacterial performance characterization of clarithromycin nanoparticles as colloidal drug delivery system
    Ghobad Mohammadi
    Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran
    Colloids Surf B Biointerfaces 88:39-44. 2011
    ..aureus with improved MICs and appropriate physicochemical properties that may be useful for other susceptible microorganisms and could be an appropriate candidate for intravenous, ocular and oral and topical preparations...
  15. ncbi request reprint An investigation of physicochemical properties of piroxicam liquisolid compacts
    Yousef Javadzadeh
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Iran
    Pharm Dev Technol 12:337-43. 2007
    ..The results of DSC and X-ray crystallography did not show any changes in crystallinity of the drug and interaction between piroxicam and exipients (Avicel and silica) during the process...
  16. ncbi request reprint Kinetic analysis of drug release from nanoparticles
    Mohammad Barzegar-Jalali
    Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    J Pharm Pharm Sci 11:167-77. 2008
    ..Theoretical justification for the two best general models was also provided for the first time...
  17. pmc Development of pH-sensitive insulin nanoparticles using Eudragit L100-55 and chitosan with different molecular weights
    Mitra Jelvehgari
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    AAPS PharmSciTech 11:1237-42. 2010
    ..These results suggest that the complex coacervation process using chitosan and Eudragit L100-55 polymers may provide a useful approach for entrapment of hydrophilic polypeptides without affecting their conformation...
  18. ncbi request reprint Physicochemical characterization of solid dispersions of indomethacin with PEG 6000, Myrj 52, lactose, sorbitol, dextrin, and Eudragit E100
    Hadi Valizadeh
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Drug Dev Ind Pharm 30:303-17. 2004
    ..However, the results from infrared spectroscopy together with those from x-ray diffraction showed well-defined drug-carrier interactions for dextrin coevaporates...
  19. doi request reprint Spironolactone loaded nanostructured lipid carrier gel for effective treatment of mild and moderate acne vulgaris: A randomized, double-blind, prospective trial
    Hamid Reza Kelidari
    Pharmaceutical Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran
    Colloids Surf B Biointerfaces 146:47-53. 2016
    ..05) increased from 37.44±8.85 to 45.69±19.34 instrumental units. Therefore, the SP-NLC gel may help in controlling acne vulgaris with skin care benefits. ..
  20. doi request reprint The design of naproxen solid lipid nanoparticles to target skin layers
    Jafar Akbari
    Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
    Colloids Surf B Biointerfaces 145:626-33. 2016
    ..This indicates that most of the drug in Nap-SLN8 remains in the skin which can reduce the side effect of systemic absorption of the drug and increases the concentration of the drug at the site of the action. ..
  21. doi request reprint Time to overcome fluconazole resistant Candida isolates: Solid lipid nanoparticles as a novel antifungal drug delivery system
    Maryam Moazeni
    Invasive Fungi Research Centre IFRC Department of Medical Mycology and Parasitology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
    Colloids Surf B Biointerfaces 142:400-7. 2016
    ..In this study, we evaluated novel delivery systems for combating Candida strains that exhibit low susceptibility against the conventional formulation of FLZ as a first-line treatment. ..
  22. pmc Gliclazide microcrystals prepared by two methods of in situ micronization: pharmacokinetic studies in diabetic and normal rats
    Roya Talari
    Department of Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences, and Isfahan Pharmaceutical Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
    AAPS PharmSciTech 11:786-92. 2010
    ..Administration of 40 mg/kg of GL in the form of untreated drug and microcrystals obtained by solvent-change and pH-shift methods caused 12.49% and 21.04% enhancement in glucose-lowering effect of GL in diabetic rats, respectively...
  23. doi request reprint Comparing various techniques to produce micro/nanoparticles for enhancing the dissolution of celecoxib containing PVP
    Alireza Homayouni
    Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
    Eur J Pharm Biopharm 88:261-74. 2014
    ..g., 5%). At high PVP concentration (e.g., 50%) all methods used to prepare engineered CLX particles showed better dissolution with no significant differences in their dissolution efficiency...
  24. ncbi request reprint An in vitro evaluation of fenugreek mucilage as a potential excipient for oral controlled-release matrix tablet
    Ali Nokhodchi
    Medway School of Pharmacy, The University of Kent and Greenwich, Chatham Maritime, Kent, UK
    Drug Dev Ind Pharm 34:323-9. 2008
    ..This is due to a reduction in tortuoisity and increased pore size of channels caused by lactose through which propranolol diffuses and therefore diffusion of water into the tablet is facilitated...
  25. ncbi request reprint The microsponge delivery system of benzoyl peroxide: preparation, characterization and release studies
    M Jelvehgari
    School of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    Int J Pharm 308:124-32. 2006
    ..The results showed that, generally, an increase in the ratio of drug:polymer resulted in a reduction in the release rate of BPO from microsponges which was attributed to a decreased internal porosity of the microsponges...
  26. ncbi request reprint Piroxicam nanoparticles for ocular delivery: physicochemical characterization and implementation in endotoxin-induced uveitis
    Khosro Adibkia
    Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran
    J Drug Target 15:407-16. 2007
    ..Upon these findings, we propose that the piroxicam:Eudragit RS100 nanosuspensions may be considered as an improved ocular delivery system for locally inhibition of inflammation...
  27. ncbi request reprint A drug release study from hydroxypropylmethylcellulose (HPMC) matrices using QSPR modeling
    Taravat Ghafourian
    Drug Applied Research Center and School of Pharmacy, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz, Iran
    J Pharm Sci 96:3334-51. 2007
    ..The results indicated that the source of the difference could be sought in the drug properties (as exemplified by the aqueous solubility and surface area) as well as the rate of erosion (that depends mainly on the polymer type)...
  28. ncbi request reprint Particle design of naproxen-disintegrant agglomerates for direct compression by a crystallo-co-agglomeration technique
    Maryam Maghsoodi
    School of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    Int J Pharm 351:45-54. 2008
    ....
  29. doi request reprint Effect of various surfactants and their concentration on controlled release of captopril from polymeric matrices
    Ali Nokhodchi
    Medway School of Pharmacy, The University of Kent and Greenwich, Central Av, Chatham Maritime ME4 4TB Kent, UK
    Acta Pharm 58:151-62. 2008
    ..The kinetic analysis of drug release data from various formulations showed that incorporation of surfactants in HPMC/EC matrices did not produce a zero-order release pattern...
  30. ncbi request reprint Factors affecting the release of nifedipine from a swellable elementary osmotic pump
    Ali Nokhodchi
    School of Pharmacy at Medway, Universities of Kent and Greenwich, Kent, England
    Drug Deliv 15:43-8. 2008
    ..The zero-order release lasted for 10 hr at pH 6.8 dissolution medium. The designed SEOP is suggested as an efficient controlled delivery system for oral delivery of a poorly water soluble drug such as nifedipine...
  31. ncbi request reprint Solubility prediction of paracetamol in water-ethanol-propylene glycol mixtures at 25 and 30 degrees C using practical approaches
    Abolghasem Jouyban
    Faculty of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Chem Pharm Bull (Tokyo) 56:602-6. 2008
    ..0+/-8.7 and 55.4+/-17.8%, respectively; the corresponding values for the predicted solubilities in mixtures having a cosolvent concentration of <50% were 12.0+/-9.1 and 22.0+/-11.0%...
  32. ncbi request reprint The effect of various surfactants on the release rate of propranolol hydrochloride from hydroxypropylmethylcellulose (HPMC)-Eudragit matrices
    Ali Nokhodchi
    School of Pharmacy, Tabriz Medical Sciences University, Tabriz, Iran
    Eur J Pharm Biopharm 54:349-56. 2002
    ..It can be concluded that, the type and ionization of surfactant, hydrophilicity and lipophilicity of surface active agent and various ratios of surfactants are important factors in controlling the release rate of propranolol...
  33. ncbi request reprint Inhibition of endotoxin-induced uveitis by methylprednisolone acetate nanosuspension in rabbits
    Khosro Adibkia
    Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran
    J Ocul Pharmacol Ther 23:421-32. 2007
    ....
  34. ncbi request reprint Swellable elementary osmotic pump (SEOP): an effective device for delivery of poorly water-soluble drugs
    Javad Shokri
    Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Eur J Pharm Biopharm 68:289-97. 2008
    ..This study also revealed that optimization of semipermeable membrane thickness is very important for approaching zero order kinetics...
  35. ncbi request reprint QSPR models for the prediction of apparent volume of distribution
    Taravat Ghafourian
    Drug Design and Chemometrics Laboratory, Drug Applied Research Centre and School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Int J Pharm 319:82-97. 2006
    ..The structural descriptors in the model can be interpreted based on the known mechanisms of distribution and the molecular structures of the drugs...