Benjamin M Neale

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint A twin study of dietary restraint, disinhibition and hunger: an examination of the eating inventory (three factor eating questionnaire)
    Benjamin M Neale
    Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, USA
    Twin Res 6:471-8. 2003
  2. ncbi request reprint A genome scan of neuroticism in nicotine dependent smokers
    Benjamin M Neale
    Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Medical College of Virginia Commonwealth University, Richmond, Virginia, USA
    Am J Med Genet B Neuropsychiatr Genet 132:65-9. 2005
  3. pmc Two independent alleles at 6q23 associated with risk of rheumatoid arthritis
    Robert M Plenge
    Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
    Nat Genet 39:1477-82. 2007
  4. doi request reprint The positives, protocols, and perils of genome-wide association
    Benjamin M Neale
    Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    Am J Med Genet B Neuropsychiatr Genet 147:1288-94. 2008
  5. pmc Common variants at CD40 and other loci confer risk of rheumatoid arthritis
    Soumya Raychaudhuri
    Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
    Nat Genet 40:1216-23. 2008
  6. ncbi request reprint Population differences in the International Multi-Centre ADHD Gene Project
    Benjamin M Neale
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Genet Epidemiol 32:98-107. 2008
  7. ncbi request reprint Further considerations for power in sibling interaction models
    Benjamin M Neale
    Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King, s College, London, UK
    Behav Genet 35:671-4. 2005
  8. doi request reprint Genetic heterogeneity in ADHD: DAT1 gene only affects probands without CD
    Kaixin Zhou
    MRC Social Genetic Developmental and Psychiatry Centre, Institute of Psychiatry, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 147:1481-7. 2008
  9. pmc Genome-wide association scan of attention deficit hyperactivity disorder
    Benjamin M Neale
    Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Am J Med Genet B Neuropsychiatr Genet 147:1337-44. 2008
  10. pmc Linkage to chromosome 1p36 for attention-deficit/hyperactivity disorder traits in school and home settings
    Kaixin Zhou
    MRC Social Genetic Developmental and Psychiatry Centre, King s College London, London, UK
    Biol Psychiatry 64:571-6. 2008

Detail Information

Publications18

  1. ncbi request reprint A twin study of dietary restraint, disinhibition and hunger: an examination of the eating inventory (three factor eating questionnaire)
    Benjamin M Neale
    Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, USA
    Twin Res 6:471-8. 2003
    ..Furthermore, Restraint appeared to be empirically distinct from Hunger or Disinhibition...
  2. ncbi request reprint A genome scan of neuroticism in nicotine dependent smokers
    Benjamin M Neale
    Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Medical College of Virginia Commonwealth University, Richmond, Virginia, USA
    Am J Med Genet B Neuropsychiatr Genet 132:65-9. 2005
    ..52 and 1.97 (P-value of 0.003 and 0.0108) respectively, and have some evidence for a novel finding on chromosome 12 with a LOD of 2.85 (P-value of 0.0014)...
  3. pmc Two independent alleles at 6q23 associated with risk of rheumatoid arthritis
    Robert M Plenge
    Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
    Nat Genet 39:1477-82. 2007
    ..We show that these two SNP associations are statistically independent, are each reproducible in the comparison of our data and WTCCC data, and define risk and protective haplotypes for rheumatoid arthritis at 6q23...
  4. doi request reprint The positives, protocols, and perils of genome-wide association
    Benjamin M Neale
    Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    Am J Med Genet B Neuropsychiatr Genet 147:1288-94. 2008
    ..We conclude with a look toward future developments such as the analysis of copy number variation and integration of expression and epigenetic phenomenon into genome-wide association...
  5. pmc Common variants at CD40 and other loci confer risk of rheumatoid arthritis
    Soumya Raychaudhuri
    Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
    Nat Genet 40:1216-23. 2008
    ..1 x 10(-7) overall), CDK6 (rs42041, P = 0.010 replication, P = 4.0 x 10(-6) overall), PRKCQ (rs4750316, P = 0.0078 replication, P = 4.4 x 10(-6) overall), and KIF5A-PIP4K2C (rs1678542, P = 0.0026 replication, P = 8.8 x 10(-8) overall)...
  6. ncbi request reprint Population differences in the International Multi-Centre ADHD Gene Project
    Benjamin M Neale
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Genet Epidemiol 32:98-107. 2008
    ..Any case-control sample employing an Israeli sample with Northern Europeans must consider stratification. A Northern European tag set, however, appears to be appropriate for capturing the variation across populations...
  7. ncbi request reprint Further considerations for power in sibling interaction models
    Benjamin M Neale
    Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King, s College, London, UK
    Behav Genet 35:671-4. 2005
    ..Additionally, the power from URs is attenuated when common environment is part of the genetic model...
  8. doi request reprint Genetic heterogeneity in ADHD: DAT1 gene only affects probands without CD
    Kaixin Zhou
    MRC Social Genetic Developmental and Psychiatry Centre, Institute of Psychiatry, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 147:1481-7. 2008
    ..Although the result needs further replications, it does highlight the importance of selecting genetically homogeneous samples for molecular genetic analyses of ADHD...
  9. pmc Genome-wide association scan of attention deficit hyperactivity disorder
    Benjamin M Neale
    Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Am J Med Genet B Neuropsychiatr Genet 147:1337-44. 2008
    ..We additionally identify a systemic bias in family-based association, and suggest that variable missing genotype rates may be the source of this bias...
  10. pmc Linkage to chromosome 1p36 for attention-deficit/hyperactivity disorder traits in school and home settings
    Kaixin Zhou
    MRC Social Genetic Developmental and Psychiatry Centre, King s College London, London, UK
    Biol Psychiatry 64:571-6. 2008
    ..The International Multi-centre ADHD Genetics (IMAGE) project performed a whole genome linkage scan specifically designed to map ADHD quantitative trait loci (QTL)...
  11. pmc The future of association studies: gene-based analysis and replication
    Benjamin M Neale
    Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Am J Hum Genet 75:353-62. 2004
    ....
  12. pmc The IMAGE project: methodological issues for the molecular genetic analysis of ADHD
    Jonna Kuntsi
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Behav Brain Funct 2:27. 2006
    ....
  13. ncbi request reprint The value of four mental health self-report scales in predicting interview-based mood and anxiety disorder diagnoses in sibling pairs
    Richard J Williamson
    MRC, SGDP, Institute of Psychiatry, King s College London, London, United Kingdom
    Twin Res Hum Genet 8:101-7. 2005
    ..The results from the present study therefore validated the four mental health measures as being predictive of psychiatric caseness...
  14. pmc Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration
    Claire L Simpson
    Department of Neurology, King s College London, London SE5 8AF, UK
    Hum Mol Genet 18:472-81. 2009
    ..01). These findings add to the growing body of evidence implicating the RNA processing pathway in neurodegeneration and suggest a critical role for ELP3 in neuron biology and of ELP3 variants in ALS...
  15. ncbi request reprint Candidate genes for nicotine dependence via linkage, epistasis, and bioinformatics
    Patrick F Sullivan
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, VA, USA
    Am J Med Genet B Neuropsychiatr Genet 126:23-36. 2004
    ..Although the hypotheses resulting from these linkage and bioinformatic analyses are plausible and intriguing, their ultimate worth depends on replication in additional linkage samples and in future experimental studies...
  16. ncbi request reprint Comorbidity of tic disorders & ADHD: conceptual and methodological considerations
    Tobias Banaschewski
    Child and Adolescent Psychiatry, University of Goettingen, Goettingen, Germany
    Eur Child Adolesc Psychiatry 16:5-14. 2007
    ..Unfortunately, conceptual and methodological problems can restrain possible conclusions from these studies...
  17. ncbi request reprint Intentional weight loss in young adults: sex-specific genetic and environmental effects
    Anna Keski-Rahkonen
    Department of Public Health, University of Helsinki, Finland
    Obes Res 13:745-53. 2005
    ..To explore eating styles associated with intentional weight loss (IWL) and to determine whether the genetic liability in IWL is entirely shared with genetic liability affecting BMI...
  18. pmc Nonpaternity in linkage studies of extremely discordant sib pairs
    Michael C Neale
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298 0126, USA
    Am J Hum Genet 70:526-9. 2002
    ..The proportion in discordant pairs may be much higher. The present article explores this potential inflation as a function of the resemblance of sib pairs and the criteria for discordance used for selection...