R M Murray

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint The developmental 'risk factor' model of schizophrenia
    R M Murray
    Department of Psychological Medicine, Institute of Psychiatry and King s College School of Medicine, London, UK
    J Psychiatr Res 33:497-9. 1999
  2. doi request reprint Combining dimensional and categorical representation of psychosis: the way forward for DSM-V and ICD-11?
    A Demjaha
    Division of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
    Psychol Med 39:1943-55. 2009
  3. ncbi request reprint Attenuated frontal activation during a verbal fluency task in patients with schizophrenia
    V A Curtis
    Department of Psychological Medicine, Institute of Psychiatry, London, United Kingdom
    Am J Psychiatry 155:1056-63. 1998
  4. ncbi request reprint Attenuated frontal activation in schizophrenia may be task dependent
    V A Curtis
    Department of Psychological Medicine, Institute of Psychiatry King s College, London, UK
    Schizophr Res 37:35-44. 1999
  5. ncbi request reprint Differential activation of temporal cortex during sentence completion in schizophrenic patients with and without formal thought disorder
    T T Kircher
    Department of Psychological Medicine, Institute of Psychiatry and GKT SchooI of Medicine, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 50:27-40. 2001
  6. pmc Abnormal cortisol awakening response predicts worse cognitive function in patients with first-episode psychosis
    M Aas
    Department of Psychological Medicine, Institute of Psychiatry, King s College London, UK
    Psychol Med 41:463-76. 2011
  7. ncbi request reprint Does dysplasia cause anatomical dysconnectivity in schizophrenia?
    E T Bullmore
    Department of Psychological Medicine and Biostatistics, Institute of Psychiatry, De Crespigny Park, London, UK
    Schizophr Res 30:127-35. 1998
  8. doi request reprint Genetic modelling of childhood social development and personality in twins and siblings with schizophrenia
    M M Picchioni
    Division of Psychological Medicine, Institute of Psychiatry, King s College London, London, UK
    Psychol Med 40:1305-16. 2010
  9. ncbi request reprint Life events, ethnicity and perceptions of discrimination in patients with severe mental illness
    C M Gilvarry
    Department of Psychological Medicine, Institute of Psychiatry, Denmark Hill, London, UK
    Soc Psychiatry Psychiatr Epidemiol 34:600-8. 1999
  10. doi request reprint Unemployment, ethnicity and psychosis
    J Boydell
    Department of Psychosis Studies, Institute of Psychiatry, London, UK
    Acta Psychiatr Scand 127:202-9. 2013

Detail Information

Publications85

  1. ncbi request reprint The developmental 'risk factor' model of schizophrenia
    R M Murray
    Department of Psychological Medicine, Institute of Psychiatry and King s College School of Medicine, London, UK
    J Psychiatr Res 33:497-9. 1999
    ..This ultimately projects the individual across the threshold for expression of schizophrenia, sometimes by causing the drug abuse and social adversity that appear to precipitate the psychosis...
  2. doi request reprint Combining dimensional and categorical representation of psychosis: the way forward for DSM-V and ICD-11?
    A Demjaha
    Division of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
    Psychol Med 39:1943-55. 2009
    ..We investigated symptom dimensions in a first-onset psychosis sample and examined their associations with risk indicators and clinical variables. We then examined the relationship of categorical diagnoses to the same variables...
  3. ncbi request reprint Attenuated frontal activation during a verbal fluency task in patients with schizophrenia
    V A Curtis
    Department of Psychological Medicine, Institute of Psychiatry, London, United Kingdom
    Am J Psychiatry 155:1056-63. 1998
    ..Functional magnetic resonance imaging was used to study changes in cerebral blood oxygenation in schizophrenic patients during a verbal fluency task...
  4. ncbi request reprint Attenuated frontal activation in schizophrenia may be task dependent
    V A Curtis
    Department of Psychological Medicine, Institute of Psychiatry King s College, London, UK
    Schizophr Res 37:35-44. 1999
    ..Functional magnetic resonance imaging was used to examine the neural correlates of two linguistic tasks in schizophrenia...
  5. ncbi request reprint Differential activation of temporal cortex during sentence completion in schizophrenic patients with and without formal thought disorder
    T T Kircher
    Department of Psychological Medicine, Institute of Psychiatry and GKT SchooI of Medicine, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 50:27-40. 2001
    ....
  6. pmc Abnormal cortisol awakening response predicts worse cognitive function in patients with first-episode psychosis
    M Aas
    Department of Psychological Medicine, Institute of Psychiatry, King s College London, UK
    Psychol Med 41:463-76. 2011
    ....
  7. ncbi request reprint Does dysplasia cause anatomical dysconnectivity in schizophrenia?
    E T Bullmore
    Department of Psychological Medicine and Biostatistics, Institute of Psychiatry, De Crespigny Park, London, UK
    Schizophr Res 30:127-35. 1998
    ..We conclude that anatomical dysconnectivity (between frontal and temporal cortex) in schizophrenia may be caused by dysplasia...
  8. doi request reprint Genetic modelling of childhood social development and personality in twins and siblings with schizophrenia
    M M Picchioni
    Division of Psychological Medicine, Institute of Psychiatry, King s College London, London, UK
    Psychol Med 40:1305-16. 2010
    ..This study aimed to establish the degree to which these childhood and adolescent developmental abnormalities are genetically determined...
  9. ncbi request reprint Life events, ethnicity and perceptions of discrimination in patients with severe mental illness
    C M Gilvarry
    Department of Psychological Medicine, Institute of Psychiatry, Denmark Hill, London, UK
    Soc Psychiatry Psychiatr Epidemiol 34:600-8. 1999
    ..We sought to test the hypothesis that B&EM patients experience more negative life events than their WB counterparts, and to examine the extent to which they attribute these events to discrimination...
  10. doi request reprint Unemployment, ethnicity and psychosis
    J Boydell
    Department of Psychosis Studies, Institute of Psychiatry, London, UK
    Acta Psychiatr Scand 127:202-9. 2013
    ..This study describes the incidence of psychosis in unemployed people and determines whether unemployment has a greater impact on the development of psychosis amongst Black minority groups than White groups...
  11. ncbi request reprint Schizophrenic patients and their first-degree relatives show an excess of mixed-handedness
    K G Orr
    Department of Psychological Medicine, Institute of Psychiatry, Denmark Hill, London, UK
    Schizophr Res 39:167-76. 1999
    ..There was some evidence for impaired sociability in the mixed-handed schizophrenic patients. Our results indicate that the excess of mixed-handedness in schizophrenia may have a genetic basis...
  12. ncbi request reprint Supra-regional brain systems and the neuropathology of schizophrenia
    I C Wright
    Department of Psychological Medicine, Institute of Psychiatry, King s College, Denmark Hill, London, UK
    Cereb Cortex 9:366-78. 1999
    ....
  13. doi request reprint Neonatal ultrasound results following very preterm birth predict adolescent behavioral and cognitive outcome
    C Nosarti
    Department of Psychosis Studies, Institute of Psychiatry, King s Health Partners, King s College London, London, UK
    Dev Neuropsychol 36:118-35. 2011
    ..Neonatal ultrasounds could aid in the identification of subgroups of children who are at increased risk of neurodevelopmental problems. These at risk subgroups could then be referred to appropriate early intervention services...
  14. pmc Biological and psychosocial risk factors for psychotic major depression
    M Heslin
    Institute of Psychiatry, Psychology and Neuroscience, King s College London, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Soc Psychiatry Psychiatr Epidemiol 51:233-45. 2016
    ..Few studies have investigated risk factors for psychotic major depression (PMD). We aimed to investigate the biological and psychosocial risk factors associated with PMD compared with other psychotic disorders...
  15. doi request reprint Theory of Mind as a potential trait marker of schizophrenia: a family study
    A D Pentaraki
    Division of Psychological Medicine, Institute of Psychiatry, King s College London, London, UK
    Cogn Neuropsychiatry 17:64-89. 2012
    ....
  16. ncbi request reprint Neuropsychological performance and spectrum personality traits in the relatives of patients with schizophrenia and affective psychosis
    C M Gilvarry
    Department of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, SE5 8AF, London, UK
    Psychiatry Res 101:89-100. 2001
    ..Furthermore, there exists an association between neuropsychological deficits and spectrum traits in both groups of relatives; in particular those with high paranoid traits have lower IQ scores than their less paranoid counterparts...
  17. ncbi request reprint Mapping of grey matter changes in schizophrenia
    I C Wright
    Department of Psychological Medicine, Institute of Psychiatry, London, UK
    Schizophr Res 35:1-14. 1999
    ..Analysis of the main effect of schizophrenia on regional grey matter revealed significant reductions in (a) the right temporal pole, insula and amygdala, (b) the left temporal pole, insula and dorsolateral prefrontal cortex...
  18. ncbi request reprint Two distinct patterns of treatment resistance: clinical predictors of treatment resistance in first-episode schizophrenia spectrum psychoses
    J Lally
    Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience IoPPN, King s College London, London, UK
    Psychol Med 46:3231-3240. 2016
    ....
  19. pmc Modelling the interplay between childhood and adult adversity in pathways to psychosis: initial evidence from the AESOP study
    C Morgan
    NIHR Biomedical Research Centre, and Section of Social Psychiatry, Health Service and Population Research Department, Institute of Psychiatry, King s College, London, UK
    Psychol Med 44:407-19. 2014
    ....
  20. doi request reprint Mortality in first-contact psychosis patients in the U.K.: a cohort study
    R Dutta
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, UK
    Psychol Med 42:1649-61. 2012
    ..The excess mortality following first-contact psychosis is well recognized. However, the causes of death in a complete incidence cohort and mortality patterns over time compared with the general population are unknown...
  21. doi request reprint Do COMT, BDNF and NRG1 polymorphisms influence P50 sensory gating in psychosis?
    M Shaikh
    NIHR Biomedical Research Centre, Institute of Psychiatry, King s College London South London and Maudsley NHS Foundation Trust, London, UK
    Psychol Med 41:263-76. 2011
    ....
  22. ncbi request reprint Meta-analysis of studies on genetic variation in 5-HT2A receptors and clozapine response
    M J Arranz
    Department of Psychological Medicine, Institute of Psychiatry, London, UK
    Schizophr Res 32:93-9. 1998
    ..Statistical analysis of extreme responders showed a clearer association of the 102-T/C with clozapine response. These results reinforce the hypothesis and strengthen the candidacy of these receptors as important therapeutic targets...
  23. ncbi request reprint School performance in Finnish children and later development of schizophrenia: a population-based longitudinal study
    M Cannon
    Department of Psychological Medicine, Institute of Psychiatry, London, England
    Arch Gen Psychiatry 56:457-63. 1999
    ..We examined whether children who are diagnosed as having schizophrenia in adulthood could be distinguished from their peers on performance in elementary school...
  24. ncbi request reprint Does social deprivation during gestation and early life predispose to later schizophrenia?
    D J Castle
    Genetics Section, Institute of Psychiatry, London, UK
    Soc Psychiatry Psychiatr Epidemiol 28:1-4. 1993
    ..1). The results were compatible with the notion that socio-economic deprivation during gestation and early life predisposes to later schizophrenia...
  25. pmc Childhood maltreatment is associated with increased body mass index and increased C-reactive protein levels in first-episode psychosis patients
    N Hepgul
    King s College London, Institute of Psychiatry, Department of Psychological Medicine, London, UK
    Psychol Med 42:1893-901. 2012
    ..We investigated the association between childhood maltreatment and inflammatory and metabolic biomarkers in subjects with first-episode psychosis and healthy controls...
  26. doi request reprint A functional MRI study of verbal fluency in adults with bipolar disorder and their unaffected relatives
    M P G Allin
    King s College London, Institute of Psychiatry, Department of Psychological Medicine and Psychiatry, London, UK
    Psychol Med 40:2025-35. 2010
    ..Individuals with a history of bipolar disorder demonstrate abnormalities of executive function, even during euthymia. The neural architecture underlying this and its relationship with genetic susceptibility for illness remain unclear...
  27. ncbi request reprint The Maudsley Family Study, II: Endogenous event-related potentials in familial schizophrenia
    S Frangou
    Department of Psychological Medicine, King s College School of Medicine and Dentistry, London, UK
    Schizophr Res 23:45-53. 1997
    ..These included six of the eight obligate carriers. Our results suggest that ERP abnormalities may serve as markers of genetic vulnerability in schizophrenia and may be useful in genetic linkage studies...
  28. doi request reprint Twins discordant for schizophrenia: psychopathology of the non-schizophrenic co-twins
    S V Argyropoulos
    Division of General Psychiatry and Psychological Medicine, Institute of Psychiatry, London, UK
    Acta Psychiatr Scand 118:214-9. 2008
    ..Patients with schizophrenia are more likely to suffer from mood and anxiety disorders compared with the general population. We explored the aetiology of this comorbidity using a twin study design...
  29. ncbi request reprint Incidence and distribution of first-episode mania by age: results from a 35-year study
    N Kennedy
    Section of General Psychiatry, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London, UK
    Psychol Med 35:855-63. 2005
    ..Few epidemiological studies have investigated incidence by age or age at onset distributions for mania or bipolar disorder. The current study aimed to determine these in a defined area in south-east London, over a 35-year period...
  30. pmc Diagnostic change 10 years after a first episode of psychosis
    M Heslin
    Centre for Economics of Mental and Physical Health, King s College London, London, UK
    Psychol Med 45:2757-69. 2015
    ....
  31. ncbi request reprint Pathophysiology of 'positive' thought disorder in schizophrenia
    P K McGuire
    Department of Psychological Medicine, Institute of Psychiatry, London
    Br J Psychiatry 173:231-5. 1998
    ..Formal thought disorder is a characteristic feature of psychosis, but little is known of its pathophysiology. We have investigated this in schizophrenia using positron emission tomography (PET)...
  32. pmc Incidence of schizophrenia in ethnic minorities in London: ecological study into interactions with environment
    J Boydell
    Division of Psychiological Medicine, Institute of Psychiatry, Denmark Hill, London, UK
    BMJ 323:1336-8. 2001
    ..To determine whether the incidence of schizophrenia among people from non-white ethnic minorities is greater in neighbourhoods where they constitute a smaller proportion of the total population...
  33. ncbi request reprint Association analysis between dopamine receptor genes and bipolar affective disorder
    T Li
    Department of Psychological Medicine, The Institute of Psychiatry, London, UK
    Psychiatry Res 86:193-201. 1999
    ..We also report a novel, rare one-repeat variant of the DRD4 exon 3 VNTR repeat in Chinese populations, which appears to be absent in Caucasians and is not associated with disease...
  34. ncbi request reprint Linkage analysis between bipolar affective disorder and markers on chromosome X
    H P Vallada
    Department of Psychological Medicine, Institute of Psychiatry, London, UK
    Psychiatr Genet 8:183-6. 1998
    ..We conclude that there is no evidence of a common major gene for bipolar affective disorder at Xq25-q27 in our set of families...
  35. ncbi request reprint The dysplastic net hypothesis: an integration of developmental and dysconnectivity theories of schizophrenia
    E T Bullmore
    Institute of Psychiatry, Department of Psychological Medicine, Denmark Hill, London, UK
    Schizophr Res 28:143-56. 1997
    ....
  36. doi request reprint Striatal dopamine synthesis capacity in twins discordant for schizophrenia
    P Shotbolt
    Psychiatric Imaging, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London, UK
    Psychol Med 41:2331-8. 2011
    ..Relatives of patients with schizophrenia are themselves at increased risk of developing the condition. In this study we examined striatal dopamine synthesis capacity in both members of twin pairs discordant for schizophrenia...
  37. doi request reprint Cumulative social disadvantage, ethnicity and first-episode psychosis: a case-control study
    C Morgan
    NIHR Biomedical Research Centre, and Centre for Public Mental Health, Health Service and Population Research Department, Institute of Psychiatry, King s College, London, UK
    Psychol Med 38:1701-15. 2008
    ..We sought to compare the prevalence of specific indicators of social disadvantage and isolation, and variations by ethnicity, in subjects with a first episode of psychosis and a series of healthy controls...
  38. ncbi request reprint First episodes of psychosis in Afro-Caribbean and White people. An 18-year follow-up population-based study
    N Takei
    Department of Psychological Medicine, Institute of Psychiatry, Denmark Hill, London
    Br J Psychiatry 172:147-53. 1998
    ..There have been few prospective studies of the long-term outcome of psychosis in people of Afro-Caribbean origin in the UK...
  39. ncbi request reprint Cognitive neuropsychiatric models of persecutory delusions
    N J Blackwood
    Department of Psychological Medicine, Institute of Psychiatry, London SE5 8AF, UK
    Am J Psychiatry 158:527-39. 2001
    ..The major cognitive theories of persecutory delusion formation and maintenance are critically examined in this article...
  40. ncbi request reprint The functional significance of perinatal corpus callosum damage: an fMRI study in young adults
    A M Santhouse
    Institute of Psychiatry, King s College, De Crespigny Park, London, UK
    Brain 125:1782-92. 2002
    ..On the auditory task, a deficit of activity was seen in the right temporal lobe of the callosum group. The findings reveal a plasticity of function compensating for early damage to the corpus callosum...
  41. doi request reprint Psychiatric disorder in young adults born very preterm: role of family history
    M Walshe
    NIHR Biomedical Research Centre for Mental Health, South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, King s College London, De Crespigny Park, London, SE5 8AF, UK
    Eur Psychiatry 23:527-31. 2008
    ..To investigate whether young adults born very preterm (VPT) (<33 weeks) are at increased risk for psychiatric illness in adulthood and whether a family history of psychiatric disorder further increases this risk...
  42. doi request reprint Exaggerated neural response to emotional faces in patients with bipolar disorder and their first-degree relatives
    S A Surguladze
    King s College London Institute of Psychiatry, DeCrespigny Park, London SE5 8AF, UK
    Neuroimage 53:58-64. 2010
    ..Exaggerated medial prefrontal cortical and subcortical (putamen and amygdala) responses to emotional signals may represent heritable neurobiological abnormalities underlying bipolar disorder...
  43. doi request reprint Genetic overlap between episodic memory deficits and schizophrenia: results from the Maudsley Twin Study
    S F Owens
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, King s Health Partners, UK
    Psychol Med 41:521-32. 2011
    ..In this study, we set out to quantify the genetic and environmental contributions to variance in visual and verbal memory performance, and to quantify their genetic relationship with schizophrenia...
  44. doi request reprint Ethnicity, social disadvantage and psychotic-like experiences in a healthy population based sample
    C Morgan
    NIHR Biomedical Research Centre, Health Service, England, UK
    Acta Psychiatr Scand 119:226-35. 2009
    ..We sought to investigate the prevalence and social correlates of psychotic-like experiences in a general population sample of Black and White British subjects...
  45. doi request reprint The acute effects of synthetic intravenous Delta9-tetrahydrocannabinol on psychosis, mood and cognitive functioning
    P D Morrison
    Institute of Psychiatry, The Biomedical Research Centre, King s College London, UK
    Psychol Med 39:1607-16. 2009
    ..In a study of intravenous (i.v.) synthetic THC in healthy humans, we aimed to study the relationship of the psychotic symptoms induced by THC to the consequent anxiety and neuropsychological impairment...
  46. pmc From real-world events to psychosis: the emerging neuropharmacology of delusions
    Paul D Morrison
    Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Schizophr Bull 35:668-74. 2009
    ..Here, we discuss how the 3 modulators regulate learning within the striatum and how their dysfunction may lead to delusional thinking...
  47. pmc The varying impact of type, timing and frequency of exposure to childhood adversity on its association with adult psychotic disorder
    H L Fisher
    Institute of Psychiatry, King s College London, UK
    Psychol Med 40:1967-78. 2010
    ..Therefore, we sought to explore the prevalence of more specific adverse childhood experiences amongst those with and without psychotic disorders using detailed assessments in a large epidemiological case-control sample (AESOP)...
  48. ncbi request reprint Aggressive behaviour at first contact with services: findings from the AESOP First Episode Psychosis Study
    K Dean
    Institute of Psychiatry, Kings College London, UK
    Psychol Med 37:547-57. 2007
    ..Aggressive behaviour is increased among those with schizophrenia but less is known about those with affective psychoses. Similarly, little is known about aggressive behaviour occurring at the onset of illness...
  49. ncbi request reprint Minor physical anomalies across ethnic groups in a first episode psychosis sample
    K Dean
    Division of Psychological Medicine, Institute of Psychiatry, Kings College London, UK
    Schizophr Res 89:86-90. 2007
    ..This held true across each of the four ethnic groupings. The results of this study suggest that neurodevelopmental factors play a role in the aetiology of psychosis across all ethnic groups...
  50. ncbi request reprint Grey matter correlates of minor physical anomalies in the AeSOP first-episode psychosis study
    K Dean
    Division of Psychological Medicine, Institute of Psychiatry, King s College London SE5 8AF, UK, and Department of Psychiatry, Sir Charles Gairdner Hospital, Perth, Australia
    Br J Psychiatry 189:221-8. 2006
    ..This supports a neurodevelopmental aetiology for psychotic disorders, since these anomalies and the brain are both ectodermally derived. However, little is understood about the brain regions implicated in this association...
  51. ncbi request reprint IQ in childhood psychiatric attendees predicts outcome of later schizophrenia at 21 year follow-up
    J C Munro
    Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London, UK
    Acta Psychiatr Scand 106:139-42. 2002
    ..Preschizophrenic children who merit psychiatric referral are claimed to have a particularly malevolent illness when the psychosis develops later. The 21 years outcome of a sample of such children was investigated...
  52. ncbi request reprint Functional imaging of the mechanisms underlying the bilateral field advantage
    A M Santhouse
    Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    Neuroimage 17:680-7. 2002
    ..The results suggest different processing strategies with different temporal characteristics in the bilateral and unilateral conditions, providing a novel explanation for the bilateral field advantage...
  53. ncbi request reprint Incidence of schizophrenia in south-east London between 1965 and 1997
    J Boydell
    Institute of Psychiatry, London, UK
    Br J Psychiatry 182:45-9. 2003
    ..There has been much debate about changes in the incidence of schizophrenia...
  54. ncbi request reprint beta-1,3-Glucuronyltransferase-1 gene implicated as a candidate for a schizophrenia-like psychosis through molecular analysis of a balanced translocation
    A R Jeffries
    Department of Neuroscience, Institute of Psychiatry, King s College London, Denmark Hill, London, UK
    Mol Psychiatry 8:654-63. 2003
    ..This leads us to the hypothesis that polymorphic or other variation of the 11q telomere may affect the activity of B3GAT1 and be a risk factor for schizophrenia and related psychoses in the general population...
  55. ncbi request reprint Episodic memory in schizophrenic patients and their relatives
    T Toulopoulou
    Division of Psychological Medicine Box 63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 63:261-71. 2003
    ..This study was designed to further elucidate the nature of the memory dysfunction being transmitted...
  56. ncbi request reprint Self-responsibility and the self-serving bias: an fMRI investigation of causal attributions
    N J Blackwood
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Neuroimage 20:1076-85. 2003
    ..The dorsal striatum, previously implicated in motivated behavior, mediates the self-serving bias...
  57. ncbi request reprint Persecutory delusions and the determination of self-relevance: an fMRI investigation
    N J Blackwood
    Department of Psychological Medicine, Institute of Psychiatry, London
    Psychol Med 34:591-6. 2004
    ..This study aimed to characterize these social cognitive biases in functional neuroanatomical terms...
  58. ncbi request reprint Mapping auditory hallucinations in schizophrenia using functional magnetic resonance imaging
    S S Shergill
    Wellcome Clinical Fellow, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, United Kingdom
    Arch Gen Psychiatry 57:1033-8. 2000
    ..This may reflect the acquisition of small numbers of images in each subject and the confounding effects of patients actively signaling when hallucinations occur...
  59. ncbi request reprint What risk factors tell us about the causes of schizophrenia and related psychoses
    J Kelly
    Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, England
    Curr Psychiatry Rep 2:378-85. 2000
    ..Both genetic and environmental risk factors appear to operate across diagnostic categories and therefore support a dimensional model of psychosis...
  60. pmc Modality specific neural correlates of auditory and somatic hallucinations
    S S Shergill
    Section of Neuroimaging, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, UK
    J Neurol Neurosurg Psychiatry 71:688-90. 2001
    ..Hallucinations in a given modality seem to involve areas that normally process sensory information in that modality...
  61. ncbi request reprint Is there an association between the COMT gene and P300 endophenotypes?
    E Bramon
    Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Eur Psychiatry 21:70-3. 2006
    ..However, the available neurophysiologic evidence suggests that any such association, if present, must be very subtle...
  62. ncbi request reprint Intellectual functioning in schizophrenia: a marker of neurodevelopmental damage?
    J H MacCabe
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    J Intellect Disabil Res 48:519-23. 2004
  63. ncbi request reprint The association of inequality with the incidence of schizophrenia--an ecological study
    J Boydell
    Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Soc Psychiatry Psychiatr Epidemiol 39:597-9. 2004
    ..The aim of the study was to determine whether those electoral wards with greater inequality have a higher incidence of schizophrenia...
  64. ncbi request reprint Further evidence of a cumulative effect of social disadvantage on risk of psychosis
    S A Stilo
    Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King s College London, London, UK
    Psychol Med . 2016
    ..To explore long-term associations, cumulative effects, and direction of effects...
  65. doi request reprint Impact of childhood adversities on specific symptom dimensions in first-episode psychosis
    O Ajnakina
    Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King s College London, London, UK
    Psychol Med 46:317-26. 2016
    ....
  66. doi request reprint Differences in cannabis-related experiences between patients with a first episode of psychosis and controls
    F Bianconi
    Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King s College London, London, UK
    Psychol Med 46:995-1003. 2016
    ..The aim of this study was to explore differences in self-reported cannabis experiences between FEP and non-psychotic populations...
  67. doi request reprint Bilateral hippocampal increase following first-episode psychosis is associated with good clinical, functional and cognitive outcomes
    J M Lappin
    Institute of Psychiatry, King s College London, London, UK
    Psychol Med 44:1279-91. 2014
    ..The hippocampus is a highly plastic brain region; examining change in volume, or change bilaterally, over time, can advance understanding of the substrate of recovery in psychosis...
  68. doi request reprint Gender difference in age at onset of schizophrenia: a meta-analysis
    S V Eranti
    Newham Early Intervention Service, East London Foundation Trust, Stratford Office Village, London, UK
    Psychol Med 43:155-67. 2013
    ..The aim of the study was to investigate gender differences in age of onset, and the impact of study design and setting on estimates thereof...
  69. ncbi request reprint Differential frontal activation in schizophrenia and bipolar illness during verbal fluency
    V A Curtis
    Department of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    J Affect Disord 66:111-21. 2001
    ..By using an identical methodology in matched bipolar subjects, we sought to determine whether this finding is specific to schizophrenia or a correlate of psychosis in general...
  70. ncbi request reprint Serotonergic function and negative and depressive symptomatology in schizophrenia and major depression
    K M Abel
    Institute of Psychiatry, London, UK
    Psychoneuroendocrinology 22:539-48. 1997
    ..We wished to explore whether these symptoms could be distinguished biologically by directly comparing serotonergic function in these two illnesses...
  71. ncbi request reprint Prenatal exposure to influenza epidemics and risk of mental retardation
    N Takei
    Department of Psychological Medicine, Institute of Psychiatry, London, UK
    Eur Arch Psychiatry Clin Neurosci 245:255-9. 1995
    ..Maternal exposure to influenza at approximately the third to fourth month of gestation may be risk factor for developing mental handicap...
  72. ncbi request reprint Cognitive and motor function and the size of the cerebellum in adolescents born very pre-term
    M Allin
    Institute of Psychiatry, King s College, London, UK
    Brain 124:60-6. 2001
    ..This provides further evidence implicating the cerebellum in cognition and suggests that cerebellar abnormalities may underlie some of the cognitive deficits found in individuals born very pre-term...
  73. ncbi request reprint A study of hippocampal shape anomaly in schizophrenia and in families multiply affected by schizophrenia or bipolar disorder
    S E J Connor
    Department of Neuroradiology, Kings Healthcare NHS Trust, King s College Hospital, Denmark Hill, SE5 9RS, London, UK
    Neuroradiology 46:523-34. 2004
    ....
  74. ncbi request reprint Predictors of later schizophrenia and affective psychosis among attendees at a child psychiatry department
    M Cannon
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Br J Psychiatry 178:420-6. 2001
    ..Schizophrenia has been linked with psychological problems in childhood but there is little information on precursors of affective psychosis...
  75. ncbi request reprint Verbal fluency in patients with schizophrenia and affective psychoses and their first-degree relatives
    C M Gilvarry
    Department of Psychological Medicine, Institute of Psychiatry, London
    Psychol Med 31:695-704. 2001
    ..However, in other families, relatives show largely normal neuropsychological function, and the poorer verbal performance of the schizophrenic member appears to have arisen secondary to his/her exposure to OCs...
  76. ncbi request reprint Transmission disequilibrium analysis of HLA class II DRB1, DQA1, DQB1 and DPB1 polymorphisms in schizophrenia using family trios from a Han Chinese population
    T Li
    Department of Psychological Medicine, Institute of Psychiatry, SE5 8AF, London, UK
    Schizophr Res 49:73-8. 2001
    ..However, our results are compatible with the view that this region of HLA might contain a susceptibility gene which is in linkage disequilibrium with DRB1 and DQA1 genes...
  77. ncbi request reprint Scholastic achievement at age 16 and risk of schizophrenia and other psychoses: a national cohort study
    J H MacCabe
    Department of Psychiatry, Institute of Psychiatry, King s College London, London, UK
    Psychol Med 38:1133-40. 2008
    ..We investigated whether school performance at age 16 is associated with risk of adult schizophrenia and other psychoses in a large national cohort, while controlling for multiple confounders...
  78. ncbi request reprint A quantitative genetic analysis of schizotypal personality traits
    Y M Linney
    Department of Psychological Medicine, Institute of Psychiatry, London
    Psychol Med 33:803-16. 2003
    ..Previous twin studies investigating the heritability of schizotypy have often had limited power and have failed to measure the disorganization/social anxiety component...
  79. pmc Altered resting-state functional connectivity in emotion-processing brain regions in adults who were born very preterm
    C Papini
    Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King s College London, De Crespigny Park, London, UK
    Psychol Med 46:3025-3039. 2016
    ..Here we investigated the functional integrity of the amygdala connectivity network in relation to the ability to recognize emotions from facial expressions in VPT adults...
  80. doi request reprint Impact of childhood trauma on risk of relapse requiring psychiatric hospital admission for psychosis
    N Petros
    Natalia Petros, MSc, Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King s College London, London Enrico Foglia, Bsc, Ewa Klamerus, Bsc, Faculty of Science and Technology, University of Westminster, London Stephanie Beards, PhD, Health Service and Population Research Department, Centre for Epidemiology and Public Health, Institute of Psychiatry, Psychology and Neuroscience, King s College London, London Robin M Murray, MD, FRCPsych, Sagnik Bhattacharyya, MD, PhD, Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King s College London, London, UK
    Br J Psychiatry 209:169-70. 2016
    ..Inconsistent current evidence suggests a need for further research in this area. ..
  81. ncbi request reprint Does schizophrenia result from developmental or degenerative processes?
    S M Church
    Department of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London, United Kingdom
    J Neural Transm Suppl . 2002
    ..2001), or b) whether there is an additional brain degeneration following onset of psychosis which is superimposed on the developmental impairment (Lieberman, 1999)...
  82. doi request reprint The impact of childhood adversity on the persistence of psychotic symptoms: a systematic review and meta-analysis
    A Trotta
    Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King s College London, London, UK
    Psychol Med 45:2481-98. 2015
    ..Thus we conducted a systematic review of the association between childhood adversity and the course of PE and symptoms over time...
  83. pmc Associations between the schizophrenia susceptibility gene ZNF804A and clinical outcomes in psychosis
    A Wickramasinghe
    Institute of Psychiatry, Psychology and Neuroscience, King s College London, London, UK
    Transl Psychiatry 5:e698. 2015
    ..Therefore, in addition to its potential role as a risk factor for psychosis, the ZNF804A rs1344706 A allele is associated with worse clinical outcome...
  84. ncbi request reprint Psychotic-like experiences and other antecedents of schizophrenia in children aged 9-12 years: a comparison of ethnic and migrant groups in the United Kingdom
    K R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, London, UK
    Psychol Med 38:1103-11. 2008
    ....
  85. ncbi request reprint Trends in cannabis use prior to first presentation with schizophrenia, in South-East London between 1965 and 1999
    J Boydell
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Psychol Med 36:1441-6. 2006
    ....