Mitul A Mehta

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Dopaminergic enhancement of cognitive function
    Mitul A Mehta
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College, London, UK
    Curr Pharm Des 12:2487-500. 2006
  2. ncbi request reprint Impaired set-shifting and dissociable effects on tests of spatial working memory following the dopamine D2 receptor antagonist sulpiride in human volunteers
    Mitul A Mehta
    Department of Psychiatry, Level E4, Addenbrooke s Hospital, University of Cambridge, Cambridge, CB2 2QQ, UK
    Psychopharmacology (Berl) 176:331-42. 2004
  3. ncbi request reprint Dopamine D2 receptor occupancy levels of acute sulpiride challenges that produce working memory and learning impairments in healthy volunteers
    Mitul A Mehta
    PET Psychiatry Group, MRC Clinical Sciences Centre, Hammersmith Hospital Imperial College, London, W12 0NN, UK
    Psychopharmacology (Berl) 196:157-65. 2008
  4. doi request reprint Dopamine release in the human striatum: motor and cognitive tasks revisited
    Julia M Lappin
    Institute of Psychiatry, King s College London, London, UK
    J Cereb Blood Flow Metab 29:554-64. 2009
  5. doi request reprint Limbic striatal dopamine D2/3 receptor availability is associated with non-planning impulsivity in healthy adults after exclusion of potential dissimulators
    Suzanne J Reeves
    Department of Old Age Psychiatry, Institute of Psychiatry, Kings College London, UK
    Psychiatry Res 202:60-4. 2012
  6. pmc Dissociable effects of methylphenidate, atomoxetine and placebo on regional cerebral blood flow in healthy volunteers at rest: a multi-class pattern recognition approach
    Andre F Marquand
    Department of Neuroimaging, Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, UK
    Neuroimage 60:1015-24. 2012
  7. pmc An investigation of cognitive 'branching' processes in major depression
    Nicholas D Walsh
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, UK
    BMC Psychiatry 9:69. 2009
  8. ncbi request reprint The effects of acute tyrosine and phenylalanine depletion on spatial working memory and planning in healthy volunteers are predicted by changes in striatal dopamine levels
    Mitul A Mehta
    PET Psychiatry, Cyclotron Building, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital, London, W12 0NN, UK
    Psychopharmacology (Berl) 180:654-63. 2005
  9. doi request reprint The functional anatomy of suggested limb paralysis
    Quinton Deeley
    Institute of Psychiatry, London, UK
    Cortex 49:411-22. 2013
  10. pmc Striatal sensitivity during reward processing in attention-deficit/hyperactivity disorder
    Yannis Paloyelis
    King s College London, Medical Research Council Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, UK
    J Am Acad Child Adolesc Psychiatry 51:722-732.e9. 2012

Detail Information

Publications56

  1. ncbi request reprint Dopaminergic enhancement of cognitive function
    Mitul A Mehta
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College, London, UK
    Curr Pharm Des 12:2487-500. 2006
    ....
  2. ncbi request reprint Impaired set-shifting and dissociable effects on tests of spatial working memory following the dopamine D2 receptor antagonist sulpiride in human volunteers
    Mitul A Mehta
    Department of Psychiatry, Level E4, Addenbrooke s Hospital, University of Cambridge, Cambridge, CB2 2QQ, UK
    Psychopharmacology (Berl) 176:331-42. 2004
    ..These include working memory and set-shifting deficits. Theories of DA function have predicted that distraction or impaired switching may be important determinants of such deficits...
  3. ncbi request reprint Dopamine D2 receptor occupancy levels of acute sulpiride challenges that produce working memory and learning impairments in healthy volunteers
    Mitul A Mehta
    PET Psychiatry Group, MRC Clinical Sciences Centre, Hammersmith Hospital Imperial College, London, W12 0NN, UK
    Psychopharmacology (Berl) 196:157-65. 2008
    ..DA receptor occupancy could clearly contribute to the variance in findings, although this is typically not known...
  4. doi request reprint Dopamine release in the human striatum: motor and cognitive tasks revisited
    Julia M Lappin
    Institute of Psychiatry, King s College London, London, UK
    J Cereb Blood Flow Metab 29:554-64. 2009
    ..No additional DA release was observed specific to the cognitive component of either task...
  5. doi request reprint Limbic striatal dopamine D2/3 receptor availability is associated with non-planning impulsivity in healthy adults after exclusion of potential dissimulators
    Suzanne J Reeves
    Department of Old Age Psychiatry, Institute of Psychiatry, Kings College London, UK
    Psychiatry Res 202:60-4. 2012
    ..Future studies that combine D2/3 receptor imaging with behavioral measures of impulsivity are required to further elucidate the precise relationship between individual components of trait impulsivity and brain dopaminergic function...
  6. pmc Dissociable effects of methylphenidate, atomoxetine and placebo on regional cerebral blood flow in healthy volunteers at rest: a multi-class pattern recognition approach
    Andre F Marquand
    Department of Neuroimaging, Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, UK
    Neuroimage 60:1015-24. 2012
    ..Our results demonstrate that combining ASL and PR yields a sensitive method for detecting the effects of these drugs and provides insights into the regional distribution of brain networks potentially modulated by these compounds...
  7. pmc An investigation of cognitive 'branching' processes in major depression
    Nicholas D Walsh
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, UK
    BMC Psychiatry 9:69. 2009
    ..Evidence for this model comes from functional neuroimaging and frontal-pole lesion patients. We have utilised these new concepts to investigate the possibility that patients with depression are impaired at cognitive 'branching'...
  8. ncbi request reprint The effects of acute tyrosine and phenylalanine depletion on spatial working memory and planning in healthy volunteers are predicted by changes in striatal dopamine levels
    Mitul A Mehta
    PET Psychiatry, Cyclotron Building, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital, London, W12 0NN, UK
    Psychopharmacology (Berl) 180:654-63. 2005
    ..However, the findings from studies in humans to date are mixed. While this may be due to the characteristics of the tasks used, it is also possible that these findings are explained by variable central effects of the manipulations used...
  9. doi request reprint The functional anatomy of suggested limb paralysis
    Quinton Deeley
    Institute of Psychiatry, London, UK
    Cortex 49:411-22. 2013
    ....
  10. pmc Striatal sensitivity during reward processing in attention-deficit/hyperactivity disorder
    Yannis Paloyelis
    King s College London, Medical Research Council Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, UK
    J Am Acad Child Adolesc Psychiatry 51:722-732.e9. 2012
    ..We investigated striatal responsivity to rewards in ADHD combined type (ADHD-CT) using functional magnetic resonance imaging (fMRI), and whether it is modulated by variation in the dopamine transporter gene (DAT1)...
  11. pmc Methylphenidate ('Ritalin') can ameliorate abnormal risk-taking behavior in the frontal variant of frontotemporal dementia
    Shibley Rahman
    Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge, UK
    Neuropsychopharmacology 31:651-8. 2006
    ..The results are discussed in terms of the 'somatic marker' hypothesis of impaired decision-making following orbitofrontal dysfunction...
  12. doi request reprint Significant decreases in frontal and temporal [11C]-raclopride binding after THC challenge
    Paul R A Stokes
    MRC Clinical Science Centre, Imperial College, Hammersmith Hospital, London, UK
    Neuroimage 52:1521-7. 2010
    ..The interpretation of these findings in relation to prefrontal dopamine release is discussed...
  13. ncbi request reprint Striatal dopamine (D2) receptor availability predicts socially desirable responding
    Suzanne J Reeves
    Section of Old Age Psychiatry, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Neuroimage 34:1782-9. 2007
    ..How this relates to dopaminergic tone will need to be further explored...
  14. pmc Nature or nurture? Determining the heritability of human striatal dopamine function: an [18F]-DOPA PET study
    Paul R A Stokes
    Psychiatric Imaging Group, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London, UK
    Neuropsychopharmacology 38:485-91. 2013
    ....
  15. ncbi request reprint Sulpiride and mnemonic function: effects of a dopamine D2 receptor antagonist on working memory, emotional memory and long-term memory in healthy volunteers
    Mitul A Mehta
    PET Psychiatry Group, MRC CSC, Imperial College, Hammersmith Hospital, London, UK
    J Psychopharmacol 19:29-38. 2005
    ..These findings question the precise role of dopamine D2 receptor modulation on WM, and highlight the need for sensitive tests to study dopaminergic modulation of emotional processing...
  16. ncbi request reprint A positron emission tomography (PET) investigation of the role of striatal dopamine (D2) receptor availability in spatial cognition
    Suzanne J Reeves
    Section of Old Age Psychiatry, Institute of Psychiatry, De Crespigny Park, London, UK
    Neuroimage 28:216-26. 2005
    ....
  17. pmc Presynaptic 5-HT1A is related to 5-HTT receptor density in the human brain
    Subrata K Bose
    PET Methodology, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, London, UK
    Neuropsychopharmacology 36:2258-65. 2011
    ..This latter finding may reflect differences in 5-HT tone between individuals, and highlights probable substrates sensitive to variations in DRN 5-HT function...
  18. pmc Pattern classification of working memory networks reveals differential effects of methylphenidate, atomoxetine, and placebo in healthy volunteers
    Andre F Marquand
    Department of Neuroimaging, Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, UK
    Neuropsychopharmacology 36:1237-47. 2011
    ..Thus, interactions between drug effects and motivational state are crucial in defining the effects of MPH and ATX...
  19. pmc The effects of the COMT Val108/158Met polymorphism on BOLD activation during working memory, planning, and response inhibition: a role for the posterior cingulate cortex?
    Paul R A Stokes
    Psychiatry Group, MRC Clinical Science Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, London, UK
    Neuropsychopharmacology 36:763-71. 2011
    ....
  20. doi request reprint Can recreational doses of THC produce significant dopamine release in the human striatum?
    Paul R A Stokes
    Psychiatry Group, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital Campus, London, UK
    Neuroimage 48:186-90. 2009
    ..In animals, Delta9-tetrahydrocannabinol (THC) increases the rate of dopamine neuronal firing and release in the striatum. Thus cannabis use may increase dopamine release in the human striatum leading to vulnerability to psychosis...
  21. doi request reprint Measuring fMRI reliability with the intra-class correlation coefficient
    Alejandro Caceres
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, UK
    Neuroimage 45:758-68. 2009
    ..The method is applied to an auditory and a verbal working memory task. A reliability toolbox for SPM5 is provided at http://brainmap.co.uk...
  22. doi request reprint Increased cerebral perfusion in adult attention deficit hyperactivity disorder is normalised by stimulant treatment: a non-invasive MRI pilot study
    Ruth L O'Gorman
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, UK
    Neuroimage 42:36-41. 2008
    ....
  23. doi request reprint A dose of ruthlessness: interpersonal moral judgment is hardened by the anti-anxiety drug lorazepam
    Adam M Perkins
    Department of Neuroimaging, Institute of Psychiatry, King s College London, London, United Kingdom
    J Exp Psychol Gen 142:612-20. 2013
    ..This finding implies that its specific capacity to increase ruthlessness in moral-personal dilemmas was not a confound caused by sedation...
  24. doi request reprint Modelling psychiatric and cultural possession phenomena with suggestion and fMRI
    Quinton Deeley
    Cultural and Social Neuroscience Research Group, Forensic and Neurodevelopmental Sciences, Kings College London, Institute of Psychiatry, London, UK South London and Maudsley NHS Foundation Trust, Bethlem Royal Hospital, Beckenham, Kent, UK Electronic address
    Cortex 53:107-19. 2014
    ..These findings caution against generalization about single cognitive processes or brain systems underpinning different experiences of loss of self-control of movement. ..
  25. pmc DAT1 and COMT effects on delay discounting and trait impulsivity in male adolescents with attention deficit/hyperactivity disorder and healthy controls
    Yannis Paloyelis
    MRC SDGP Centre, Institute of Psychiatry, King s College London, London, UK
    Neuropsychopharmacology 35:2414-26. 2010
    ..The lack of magnitude effects in the hypothetical task suggests that discounting in this task may be influenced by different processes in ADHD-CT than in healthy controls...
  26. pmc The test-retest reliability of 18F-DOPA PET in assessing striatal and extrastriatal presynaptic dopaminergic function
    Alice Egerton
    Psychiatric Imaging, Medical Research Council Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London, UK
    Neuroimage 50:524-31. 2010
    ..This information can be used to optimize the experimental design of future studies investigating changes in brain dopaminergic function with 18F-DOPA...
  27. doi request reprint The effect of ageing on grey and white matter reductions in schizophrenia
    Subrata K Bose
    MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, UK
    Schizophr Res 112:7-13. 2009
    ..This suggests that illness related factors may differentially affect grey and white matter, with implications for understanding the pathophysiology of schizophrenia and related psychotic disorders...
  28. doi request reprint The functional anatomy and connectivity of thought insertion and alien control of movement
    Eamonn Walsh
    Cultural and Social Neuroscience Research Group, Forensic and Neurodevelopmental Sciences, Kings College London, Institute of Psychiatry, Psychology and Neuroscience, London, UK Department of Psychological Sciences, Birkbeck, University of London, London, UK Electronic address
    Cortex 64:380-93. 2015
    ..Collectively these results indicate the SMA plays a central role in alien control phenomena as a high level executive system involved in the sense that we control and own our thoughts and movements. ..
  29. pmc Using hypnotic suggestion to model loss of control and awareness of movements: an exploratory FMRI study
    Quinton Deeley
    Cultural and Social Neuroscience Research Group, Forensic and Neurodevelopmental Sciences, Kings College London, Institute of Psychiatry, London, United Kingdom
    PLoS ONE 8:e78324. 2013
    ....
  30. ncbi request reprint The neural correlates of declining performance with age: evidence for age-related changes in cognitive control
    David J Sharp
    MRC Cyclotron Unit, Clinical Sciences Centre, Imperial College, London, UK
    Cereb Cortex 16:1739-49. 2006
    ..Thus, the ACC and lateral PFC show distinct responses to age-related decline in decision-making performance. This suggests that greater cognitive control is employed as individuals age and their performance declines...
  31. ncbi request reprint Human cognition assessment in drug research
    Wim J Riedel
    Psychiatry Discovery Medicine, GlaxoSmithKline R and D, Cambridge, UK
    Curr Pharm Des 12:2525-39. 2006
    ..The associated factor analytical-, resource-strategy- and staged information processing models respectively are described. Finally a brief review is presented on possible physiological markers or biomarkers of human cognitive functions...
  32. pmc Acute effect of the anti-addiction drug bupropion on extracellular dopamine concentrations in the human striatum: an [11C]raclopride PET study
    Alice Egerton
    Psychiatric Imaging, Medical Research Council Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
    Neuroimage 50:260-6. 2010
    ..These findings have important implications for understanding the mechanism of action underlying bupropions' therapeutic efficacy and for the development of novel treatments for addiction and depression...
  33. pmc The dopaminergic basis of human behaviors: A review of molecular imaging studies
    Alice Egerton
    Medical Research Council Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, United Kingdom
    Neurosci Biobehav Rev 33:1109-32. 2009
    ....
  34. doi request reprint The response to rapid infusion of fentanyl in the human brain measured using pulsed arterial spin labelling
    Fernando O Zelaya
    Department of Neuroimaging, Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    MAGMA 25:163-75. 2012
    ..v.) infusion of an opioid agonist (fentanyl) and an opioid antagonist (naloxone)...
  35. pmc Opposite effects of delta-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology
    Sagnik Bhattacharyya
    Section of Neuroimaging, Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, London, UK
    Neuropsychopharmacology 35:764-74. 2010
    ..Delta-9-THC and CBD can have opposite effects on regional brain function, which may underlie their different symptomatic and behavioral effects, and CBD's ability to block the psychotogenic effects of Delta-9-THC...
  36. ncbi request reprint Methylphenidate improves working memory and set-shifting in AD/HD: relationships to baseline memory capacity
    Mitul A Mehta
    University of Cambridge, Department of Psychiatry, UK
    J Child Psychol Psychiatry 45:293-305. 2004
    ..Clear delineation of the effects of methylphenidate upon such cognitive functions in AD/HD would enhance understanding of the effects of drug treatment...
  37. ncbi request reprint A longitudinal functional magnetic resonance imaging study of verbal working memory in depression after antidepressant therapy
    Nicholas D Walsh
    Institute of Psychiatry, King s College London, De Crespigny Park, 103 Denmark Hill, London, UK
    Biol Psychiatry 62:1236-43. 2007
    ..Impairments in the neural circuitry of verbal working memory are evident in depression. Factors of task demand and depressive state might have significant effects on its functional neuroanatomy...
  38. ncbi request reprint Correction of head movement on PET studies: comparison of methods
    Andrew J Montgomery
    CSC MRC Cyclotron Unit, Imperial College, Hammersmith Hospital, London, UK
    J Nucl Med 47:1936-44. 2006
    ..These include frame-by-frame (FBF) realignment or use of motion tracking (MT) during the scan to realign PET acquisition data. Here we present a comparative analysis of these 2 methods of motion correction...
  39. doi request reprint The role of machine learning in neuroimaging for drug discovery and development
    Orla M Doyle
    Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King s College London, De Crespigny Park, London, SE5 8AF, UK
    Psychopharmacology (Berl) 232:4179-89. 2015
    ..Further refinement and tailoring of machine learning techniques may help realise their tremendous potential for drug discovery and drug validation. ..
  40. pmc Using arterial spin labeling to examine mood states in youth
    Nina Mikita
    Department of Child and Adolescent Psychiatry, King s College London, Institute of Psychiatry, Psychology and Neuroscience London, UK
    Brain Behav 5:e00339. 2015
    ..Yet, it has so far been underutilized for understanding the neural mechanisms underlying mood states in youth...
  41. doi request reprint Perceptual distortions and delusional thinking following ketamine administration are related to increased pharmacological MRI signal changes in the parietal lobe
    James Stone
    Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology and Neuroscience, King s College London, London, UK
    J Psychopharmacol 29:1025-8. 2015
    ..01). The findings suggest that BOLD increases in parietal cortices reflect ketamine effects on circuits that contribute to its capacity to produce perceptual alterations and delusional interpretations...
  42. pmc Bringing memory fMRI to the clinic: comparison of seven memory fMRI protocols in temporal lobe epilepsy
    Karren Towgood
    Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King s College London, London, United Kingdom
    Hum Brain Mapp 36:1595-608. 2015
    ..We conclude that Words (event) protocol shows the best combination of between-sessions reliability of the distribution of activity between hemispheres and reliable ability to distinguish between left-onset and right-onset patients...
  43. pmc Facial affect processing deficits in schizophrenia: a meta-analysis of antipsychotic treatment effects
    Anthony S Gabay
    Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King s College London, London, UK
    J Psychopharmacol 29:224-9. 2015
    ..This highlights the need for further investigation into the neuropharmacological mechanisms associated with accurate emotion processing, to inform treatment options for these deficits in schizophrenia. ..
  44. doi request reprint Increasing pharmacological knowledge about human neurological and psychiatric disorders through functional neuroimaging and its application in drug discovery
    Pradeep J Nathan
    Brain Mapping Unit, Department of Psychiatry, Behavioural and Clinical Neuroscience Institute, University of Cambridge, UK School of Psychology and Psychiatry, Monash University, Australia New Medicines, UCB Pharma, Belgium Electronic address
    Curr Opin Pharmacol 14:54-61. 2014
    ....
  45. doi request reprint Pharmacological application of fMRI
    Mitul A Mehta
    Institute of Psychiatry at King s College London, Centre for Neuroimaging Sciences PO89, London, SE5 8AF, UK
    Methods Mol Biol 711:551-65. 2011
    ..Finally, we address methods to minimise the potential influence of non-specific drug effects and side effects on the MRI signal allowing interpretation more closely aligned to the precise research questions...
  46. doi request reprint Effects of acute nicotine on brain function in healthy smokers and non-smokers: estimation of inter-individual response heterogeneity
    Ulrich Ettinger
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, DeCrespigny Park, PO89, London SE5 8AF, UK
    Neuroimage 45:549-61. 2009
    ..The comparison of within-session ICCs across drug conditions suggests that the effects of nicotine are subject to inter-individual variability at behavioural and neural levels...
  47. pmc Functional MRI in ADHD: a systematic literature review
    Yannis Paloyelis
    MRC Social Genetic Developmental Psychiatry Centre P080, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
    Expert Rev Neurother 7:1337-56. 2007
    ....
  48. doi request reprint Amygdala, hippocampal and corpus callosum size following severe early institutional deprivation: the English and Romanian Adoptees study pilot
    Mitul A Mehta
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, UK
    J Child Psychol Psychiatry 50:943-51. 2009
    ..These pilot findings highlight the need for future studies to confirm the sensitivity of the amygdala to early deprivation...
  49. ncbi request reprint Applications of functional magnetic resonance imaging in psychiatry
    Martina T Mitterschiffthaler
    Centre for Neuroimaging Sciences, Department of Clinical Neuroscience, Institute of Psychiatry, King s College London, London, UK
    J Magn Reson Imaging 23:851-61. 2006
    ..The role of fMRI in the objective assessment of therapeutic intervention and early prediction of response to treatment is also discussed...
  50. ncbi request reprint Systemic sulpiride modulates striatal blood flow: relationships to spatial working memory and planning
    Mitul A Mehta
    PET Psychiatry, Cyclotron Building, Division of Neuroscience and Psychological Medicine, Imperial College, Hammersmith Hospital, DuCane Road, London W12 0NN, UK
    Neuroimage 20:1982-94. 2003
    ....
  51. ncbi request reprint Cognitive and motor effects of dopaminergic medication withdrawal in Parkinson's disease
    Liory Fern-Pollak
    Division of Neuroscience and MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Hospital, London W12 0NN, UK
    Neuropsychologia 42:1917-26. 2004
    ..This study aimed to clarify the role of dopaminergic medication in spatial working memory, and reinforcement-based associative learning in relation to clinical changes in motor function in early Parkinson's disease (PD)...
  52. ncbi request reprint Combined D1/D2 receptor stimulation under conditions of dopamine depletion impairs spatial working memory performance in humans
    Kathryn A Ellis
    Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia
    Psychopharmacology (Berl) 181:771-80. 2005
    ....
  53. ncbi request reprint Is psychological stress in man associated with increased striatal dopamine levels?: A [11C]raclopride PET study
    Andrew J Montgomery
    Cyclotron Unit, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College, London, United Kingdom
    Synapse 60:124-31. 2006
    ..This negative result suggests that significant DA release does not occur in the striatum in healthy humans after mild, psychological stress...
  54. ncbi request reprint Tyrosine depletion alters cortical and limbic blood flow but does not modulate spatial working memory performance or task-related blood flow in humans
    Kathryn A Ellis
    Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia
    Hum Brain Mapp 28:1136-49. 2007
    ..These findings question the capacity of TPD to consistently modulate dopamine function and SWM neural networks in humans...
  55. ncbi request reprint Where do we go from here? The importance of initial values
    Mitul A Mehta
    Neuropsychopharmacology 27:879-80; author reply 881. 2002
  56. ncbi request reprint Exploring the physiological effects of double-cone coil TMS over the medial frontal cortex on the anterior cingulate cortex: an H2(15)O PET study
    Gail Hayward
    University Department of Psychiatry, Warneford Hospital, Oxford, OX3 7JX, UK
    Eur J Neurosci 25:2224-33. 2007
    ..However, a number of more distal cortical areas were also affected in these experiments. These additional changes may reflect either 'downstream' effects of altered cingulate cortex activity or direct effects of the coil...