Julian Leff

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Can we manage without the mental hospital?
    J Leff
    Institute of Psychiatry, London, UK
    Aust N Z J Psychiatry 35:421-7. 2001
  2. ncbi request reprint Science and society: The psychiatric revolution: care in the community
    Julian Leff
    Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Nat Rev Neurosci 3:821-4. 2002
  3. ncbi request reprint Evaluation of a special rehabilitation programme for patients who are difficult to place
    Julian Leff
    TAPS, Department of Psychiatry and Behavioural Sciences, Royal Free and University College Medical School, 69 Fleet Road, London NW3 1QU, UK
    Soc Psychiatry Psychiatr Epidemiol 37:532-6. 2002
  4. doi request reprint Neurological abnormalities and cognitive ability in first-episode psychosis
    Paola Dazzan
    Department of Psychiatry, Box 63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 193:197-202. 2008
  5. pmc Interplay between childhood physical abuse and familial risk in the onset of psychotic disorders
    Helen L Fisher
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    Schizophr Bull 40:1443-51. 2014
  6. pmc Reliability and comparability of psychosis patients' retrospective reports of childhood abuse
    Helen L Fisher
    Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Schizophr Bull 37:546-53. 2011
  7. pmc Assessment of posttraumatic symptoms in patients with first-episode psychosis
    Ingo Schafer
    Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, Hamburg, Germany
    J Nerv Ment Dis 199:896-8. 2011
  8. ncbi request reprint Duration of prodromal phase and severity of volumetric abnormalities in first-episode psychosis
    Julia M Lappin
    King s College London, Institute of Psychiatry, London, UK
    Br J Psychiatry Suppl 51:s123-7. 2007
  9. ncbi request reprint Parental separation, loss and psychosis in different ethnic groups: a case-control study
    Craig Morgan
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Psychol Med 37:495-503. 2007
  10. ncbi request reprint Duration of untreated psychosis and neuropsychological function in first episode psychosis
    Julia M Lappin
    Kings College Hospital Institute of Psychiatry, Division of Psychological Medicine, PO63, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Schizophr Res 95:103-10. 2007

Detail Information

Publications37

  1. ncbi request reprint Can we manage without the mental hospital?
    J Leff
    Institute of Psychiatry, London, UK
    Aust N Z J Psychiatry 35:421-7. 2001
    ..The objectives of this review are to examine the evidence on which an answer to the above question might be based...
  2. ncbi request reprint Science and society: The psychiatric revolution: care in the community
    Julian Leff
    Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Nat Rev Neurosci 3:821-4. 2002
  3. ncbi request reprint Evaluation of a special rehabilitation programme for patients who are difficult to place
    Julian Leff
    TAPS, Department of Psychiatry and Behavioural Sciences, Royal Free and University College Medical School, 69 Fleet Road, London NW3 1QU, UK
    Soc Psychiatry Psychiatr Epidemiol 37:532-6. 2002
    ..The aim of this study was to evaluate a rehabilitation programme specially designed for difficult-to-place patients in a psychiatric hospital undergoing closure...
  4. doi request reprint Neurological abnormalities and cognitive ability in first-episode psychosis
    Paola Dazzan
    Department of Psychiatry, Box 63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 193:197-202. 2008
    ....
  5. pmc Interplay between childhood physical abuse and familial risk in the onset of psychotic disorders
    Helen L Fisher
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    Schizophr Bull 40:1443-51. 2014
    ..Therefore, using a large epidemiological case-control sample, we explored the interplay between a specific form of childhood abuse and family psychiatric history (a proxy for genetic risk) in the onset of psychosis...
  6. pmc Reliability and comparability of psychosis patients' retrospective reports of childhood abuse
    Helen L Fisher
    Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Schizophr Bull 37:546-53. 2011
    ..159, P=.419; antipathy: χ(2)=0.868, P=.229; neglect: χ(2)=0.639, P=.274). These findings provide justification for the use in future studies of retrospective reports of childhood abuse obtained from individuals with psychotic disorders...
  7. pmc Assessment of posttraumatic symptoms in patients with first-episode psychosis
    Ingo Schafer
    Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, Hamburg, Germany
    J Nerv Ment Dis 199:896-8. 2011
    ..Overall, the findings suggest that the IES can be used to assess symptoms of posttraumatic stress in patients with psychotic disorders as in other populations...
  8. ncbi request reprint Duration of prodromal phase and severity of volumetric abnormalities in first-episode psychosis
    Julia M Lappin
    King s College London, Institute of Psychiatry, London, UK
    Br J Psychiatry Suppl 51:s123-7. 2007
    ..First-episode psychosis is typically preceded by a prodrome in which there is deterioration in global and social functioning...
  9. ncbi request reprint Parental separation, loss and psychosis in different ethnic groups: a case-control study
    Craig Morgan
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Psychol Med 37:495-503. 2007
    ..We sought to investigate the relationship between long-term separation from, and death of, a parent before the age of 16 and risk of adult psychosis in different ethnic groups...
  10. ncbi request reprint Duration of untreated psychosis and neuropsychological function in first episode psychosis
    Julia M Lappin
    Kings College Hospital Institute of Psychiatry, Division of Psychological Medicine, PO63, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Schizophr Res 95:103-10. 2007
    ..We predicted that longer DUP would be associated with greater neurocognitive impairment...
  11. doi request reprint Unemployment, social isolation, achievement-expectation mismatch and psychosis: findings from the AESOP Study
    Ulrich A Reininghaus
    Health Services and Population Research Department, Institute of Psychiatry, King s College, De Crespigny Park, London, UK
    Soc Psychiatry Psychiatr Epidemiol 43:743-51. 2008
    ....
  12. doi request reprint Gender differences in the association between childhood abuse and psychosis
    Helen Fisher
    PO 80, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 194:319-25. 2009
    ..Studies demonstrating an association between childhood trauma and psychosis in adulthood have not systematically explored gender differences...
  13. ncbi request reprint Sexually dimorphic changes in the amygdala in relation to delusional beliefs in first episode psychosis
    Ayana A Gibbs
    Division of Psychological Medicine, Institute of Psychiatry, King s College, P O Box, De Crespigny Park, London SE5 8AF, UK
    J Psychiatr Res 42:913-9. 2008
    ..The present study explored the relationship between amygdala morphology and mood congruent and mood incongruent delusional beliefs...
  14. ncbi request reprint Social environment, ethnicity and schizophrenia. A case-control study
    Rosemarie Mallett
    Social Psychiatry Section, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
    Soc Psychiatry Psychiatr Epidemiol 37:329-35. 2002
    ....
  15. doi request reprint Satisfaction with inpatient treatment for first-episode psychosis among different ethnic groups: a report from the UK AeSOP study
    Jane Boydell
    Psychosis Clinical Academic Group, Institute of Psychiatry, King s Health Partners, King s College London, UK
    Int J Soc Psychiatry 58:98-105. 2012
    ..There is concern about the level of satisfaction with mental healthcare among minority ethnic patients in the UK, particularly as black patients have more compulsory admissions to hospital...
  16. doi request reprint The culture and identity schedule a measure of cultural affiliation: acculturation, marginalization and schizophrenia
    Dinesh Bhugra
    Health Service and Population Research Department, Institute of Psychiatry, King s College London, UK
    Int J Soc Psychiatry 56:540-56. 2010
    ..Previous epidemiological studies have shown a high incidence of schizophrenia in African-Caribbeans in the UK, but not in Asians...
  17. ncbi request reprint Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study
    Paul Fearon
    Division of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
    Psychol Med 36:1541-50. 2006
    ..We sought to clarify whether (a) the rates of other psychotic disorders are increased, (b) whether psychosis is increased in other ethnic minority groups, and (c) whether particular age or gender groups are especially at risk...
  18. pmc Comment on paper by Cohen, Patel, Thara, and Gureje
    Julian Leff
    Institute of Psychiatry, Kings College London
    Schizophr Bull 34:251-2. 2008
  19. ncbi request reprint Gray matter abnormalities associated with duration of untreated psychosis
    Julia M Lappin
    Kings College London Institute of Psychiatry, PO63, Division of Psychological Medicine, King s College London, London SE5 8AF, United Kingdom
    Schizophr Res 83:145-53. 2006
    ..In order to identify whether an anatomically mediated mechanism may give rise to poorer outcomes, it is important to identify whether a long DUP is associated with greater brain structural abnormalities...
  20. ncbi request reprint The structural brain correlates of neurological soft signs in AESOP first-episode psychoses study
    Paola Dazzan
    Division of Psychological Medicine, Box 63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Brain 127:143-53. 2004
    ....
  21. ncbi request reprint Ethnicity, goal striving and schizophrenia: a case-control study of three ethnic groups in the United Kingdom
    Rosemarie Mallett
    Institute of Psychiatry, London, UK
    Int J Soc Psychiatry 50:331-44. 2004
    ..For those on the margins of mainstream society, especially migrants or descendants of migrants, the impact of failed or poor achievements may increase their vulnerability to mental illness...
  22. ncbi request reprint Different effects of typical and atypical antipsychotics on grey matter in first episode psychosis: the AESOP study
    Paola Dazzan
    Division of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
    Neuropsychopharmacology 30:765-74. 2005
    ..In conclusion, we would like to suggest that even after short-term treatment, typical and atypical antipsychotics may affect brain structure differently...
  23. ncbi request reprint Increased pituitary volume in antipsychotic-free and antipsychotic-treated patients of the AEsop first-onset psychosis study
    Carmine M Pariante
    Stress, Psychiatry and Immunology Laboratory, Division of Psychological Medicine, Clinical Neuropharmacology PO51, Institute of Psychiatry, King s College London, 1 Windsor Walk, Denmark Hill, London SE5 8AF, UK
    Neuropsychopharmacology 30:1923-31. 2005
    ..This activation of the hormonal stress response could participate to the important metabolic abnormalities observed in patients with psychosis...
  24. ncbi request reprint The structural brain correlates of neurological soft signs in healthy individuals
    Paola Dazzan
    King s College London, Institute of Psychiatry, Division of Psychological Medicine, London, UK
    Cereb Cortex 16:1225-31. 2006
    ..Therefore, we suggest that these cortical brain structural changes represent a common neuroanatomical substrate of NSS, across healthy individuals and patients with psychosis...
  25. ncbi request reprint Outcomes for long-term patients one year after discharge from a psychiatric hospital
    Graham Thornicroft
    Health Services Research Department, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, England, UK
    Psychiatr Serv 56:1416-22. 2005
    ....
  26. ncbi request reprint Duration of untreated psychosis and ethnicity in the AESOP first-onset psychosis study
    Craig Morgan
    Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London, UK
    Psychol Med 36:239-47. 2006
    ..There is a common assumption that Black patients with a psychotic mental illness experience longer treatment delays during a first episode. We sought to investigate this issue in a large cohort of patients with a first episode of psychosis...
  27. ncbi request reprint Differentiating the effects of pharmacological and psychosocial interventions in an intensive rehabilitation programme
    Andrew Szmidla
    Department of Mental Health Sciences, Royal Free and University College Medical School, London, UK
    Soc Psychiatry Psychiatr Epidemiol 41:734-7. 2006
    ..The aim of this study was to differentiate the effects of pharmacological and psychosocial interventions in improving the symptoms of patients with schizophrenia undergoing an intensive rehabilitation programme...
  28. ncbi request reprint Service use and costs of supporting the most socially disabled patients in a hospital reprovision programme. A two-hospital comparison
    Paul McCrone
    P024 Centre for the Economics of Mental Health, Health Services Research Dept, Institute of Psychiatry, King s College London, De Crespigny Park, London, SE5 8AF, UK
    Soc Psychiatry Psychiatr Epidemiol 41:656-61. 2006
    ..This paper compares service use and costs of difficult-to-place patients from two UK hospitals (Friern and Warley) and identifies predictors of cost. One of these hospitals (Warley) provided a more intensive programme of rehabilitation...
  29. ncbi request reprint Clinical and social determinants of duration of untreated psychosis in the AESOP first-episode psychosis study
    Craig Morgan
    Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 189:446-52. 2006
    ..Despite considerable research investigating the relationship between a long duration of untreated psychosis (DUP) and outcomes, there has been much less considering predictors of a long DUP...
  30. ncbi request reprint Improving the knowledge and skills of psychiatric nurses: efficacy of a staff training programme
    Lucy Willetts
    TAPS Research Unit, Hampstead, London, UK
    J Adv Nurs 42:237-43. 2003
    ..Few studies have been published that describe training programmes for this staff group...
  31. doi request reprint Perceptions of disadvantage, ethnicity and psychosis
    Claudia Cooper
    UCL Department of Mental Health Sciences, London W1W 7EY, UK
    Br J Psychiatry 192:185-90. 2008
    ..People from Black ethnic groups (African-Caribbean and Black African) are more prone to develop psychosis in Western countries. This excess might be explained by perceptions of disadvantage...
  32. doi request reprint Grey matter abnormalities in first-episode schizophrenia and affective psychosis
    Kevin D Morgan
    Department of Psychology, University of Westminster, 309 Regent Street, London W1B 2UW, UK
    Br J Psychiatry Suppl 51:s111-6. 2007
    ..Grey matter and other structural brain abnormalities are consistently reported in first-onset schizophrenia, but less is known about the extent of neuroanatomical changes in first-onset affective psychosis...
  33. ncbi request reprint Long-term outcome of long-stay psychiatric in-patients considered unsuitable to live in the community. TAPS Project 44
    Noam Trieman
    Chase Farm Hospital, Enfield, UK
    Br J Psychiatry 181:428-32. 2002
    ..Whereas the majority of long-stay in-patients have been successfully resettled in the community, there is a group of such patients who are too disturbed or disturbing to be managed in standard community homes...
  34. ncbi request reprint Negative pathways to psychiatric care and ethnicity: the bridge between social science and psychiatry
    Craig Morgan
    Department of Social Policy and Social Work, University of Oxford, Barnett House, 32 Wellington Square, Oxford OX1 2ER, UK
    Soc Sci Med 58:739-52. 2004
    ..This further reflects the need for a bridge between the social sciences and psychiatry if services are to be developed to respond to the increasing diversity of modern societies...
  35. ncbi request reprint Effectiveness of psychoeducational intervention for rural Chinese families experiencing schizophrenia--a randomised controlled trial
    Mao Sheng Ran
    Institute of Mental Health, West China Hospital, West China University of Medical Sciences, Chengdu, China
    Soc Psychiatry Psychiatr Epidemiol 38:69-75. 2003
    ..The aim of this study was to explore the characteristics and efficacy of psychoeducational family intervention for persons with schizophrenia in rural China...
  36. ncbi request reprint Incidence of bipolar affective disorder in three UK cities: results from the AESOP study
    Tuhina Lloyd
    Division of Psychiatry, University of Nottingham, Nottingham, UK
    Br J Psychiatry 186:126-31. 2005
    ..There has been a relative dearth of epidemiological research into bipolar affective disorder. Furthermore, incidence studies of bipolar disorder have been predominantly retrospective and most only included hospital admission cases...
  37. ncbi request reprint The characteristics of expressed emotion among relatives of patients with schizophrenia in Chengdu, China
    Mao Sheng Ran
    Department of Social Work and Social Administration, University of Hong Kong, Hong Kong
    Cult Med Psychiatry 27:95-106. 2003
    ..05). The results of this study could indicate the impact of cultural and ethnic differences and geographical location on EE...