Robert J Howard

Summary

Affiliation: King's College London
Country: UK

Publications

  1. pmc DOMINO-AD protocol: donepezil and memantine in moderate to severe Alzheimer's disease - a multicentre RCT
    Rob Jones
    Section of Old Age Psychiatry, The University of Nottingham, A Floor, South Block, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Trials 10:57. 2009
  2. ncbi request reprint Donepezil for the treatment of agitation in Alzheimer's disease
    Robert J Howard
    Medical Research Council Neurogeneration Research Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    N Engl J Med 357:1382-92. 2007
  3. ncbi request reprint Virtual in vivo interactive dissection of white matter fasciculi in the human brain
    Marco Catani
    Section of Old Age Psychiatry, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    Neuroimage 17:77-94. 2002
  4. doi request reprint Cognitive behavioral therapy for depression in older people: a meta-analysis and meta-regression of randomized controlled trials
    Rebecca L Gould
    Department of Old Age Psychiatry, Institute of Psychiatry, King s College London, London, UK
    J Am Geriatr Soc 60:1817-30. 2012
  5. ncbi request reprint A diffusion tensor imaging study of fasciculi in schizophrenia
    Sukhwinder S Shergill
    Institute of Psychiatry, Kings College London, De Crespigny Park, UK
    Am J Psychiatry 164:467-73. 2007
  6. ncbi request reprint Striatal dopamine (D2) receptor availability predicts socially desirable responding
    Suzanne J Reeves
    Section of Old Age Psychiatry, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Neuroimage 34:1782-9. 2007
  7. ncbi request reprint Functional neuroanatomy of successful paired associate learning in Alzheimer's disease
    Rebecca L Gould
    Section of Old Age Psychiatry, Box P070, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Am J Psychiatry 162:2049-60. 2005
  8. ncbi request reprint A positron emission tomography (PET) investigation of the role of striatal dopamine (D2) receptor availability in spatial cognition
    Suzanne J Reeves
    Section of Old Age Psychiatry, Institute of Psychiatry, De Crespigny Park, London, UK
    Neuroimage 28:216-26. 2005
  9. ncbi request reprint The effect of filter size on VBM analyses of DT-MRI data
    Derek K Jones
    Neuroimaging Research Group, Centre for Neuroimaging Sciences, Institute of Psychiatry, London, UK
    Neuroimage 26:546-54. 2005
  10. doi request reprint Tests of pattern separation and pattern completion in humans-A systematic review
    Kathy Y Liu
    Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King s College London, London, United Kingdom
    Hippocampus 26:705-17. 2016

Detail Information

Publications21

  1. pmc DOMINO-AD protocol: donepezil and memantine in moderate to severe Alzheimer's disease - a multicentre RCT
    Rob Jones
    Section of Old Age Psychiatry, The University of Nottingham, A Floor, South Block, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Trials 10:57. 2009
    ..The aim of this trial is to establish the most effective drug option for people with AD who are progressing from moderate to severe dementia despite treatment with donepezil...
  2. ncbi request reprint Donepezil for the treatment of agitation in Alzheimer's disease
    Robert J Howard
    Medical Research Council Neurogeneration Research Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    N Engl J Med 357:1382-92. 2007
    ..Agitation is a common and distressing symptom in patients with Alzheimer's disease. Cholinesterase inhibitors improve cognitive outcomes in such patients, but the benefits of these drugs for behavioral disturbances are unclear...
  3. ncbi request reprint Virtual in vivo interactive dissection of white matter fasciculi in the human brain
    Marco Catani
    Section of Old Age Psychiatry, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    Neuroimage 17:77-94. 2002
    ....
  4. doi request reprint Cognitive behavioral therapy for depression in older people: a meta-analysis and meta-regression of randomized controlled trials
    Rebecca L Gould
    Department of Old Age Psychiatry, Institute of Psychiatry, King s College London, London, UK
    J Am Geriatr Soc 60:1817-30. 2012
    ..To review the effectiveness of cognitive behavioral therapy (CBT) for depression in older people, together with factors associated with its efficacy...
  5. ncbi request reprint A diffusion tensor imaging study of fasciculi in schizophrenia
    Sukhwinder S Shergill
    Institute of Psychiatry, Kings College London, De Crespigny Park, UK
    Am J Psychiatry 164:467-73. 2007
    ..This study used diffusion tensor imaging to examine the integrity of the major white matter fasciculi, which connects the frontal and temporal-parietal cortices, and the corpus callosum in patients with schizophrenia...
  6. ncbi request reprint Striatal dopamine (D2) receptor availability predicts socially desirable responding
    Suzanne J Reeves
    Section of Old Age Psychiatry, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Neuroimage 34:1782-9. 2007
    ..How this relates to dopaminergic tone will need to be further explored...
  7. ncbi request reprint Functional neuroanatomy of successful paired associate learning in Alzheimer's disease
    Rebecca L Gould
    Section of Old Age Psychiatry, Box P070, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Am J Psychiatry 162:2049-60. 2005
    ..The purpose of the study was to develop a strategy for functional imaging of neurodegenerative disorders that overcomes confounds associated with differential performance between patient and comparison groups...
  8. ncbi request reprint A positron emission tomography (PET) investigation of the role of striatal dopamine (D2) receptor availability in spatial cognition
    Suzanne J Reeves
    Section of Old Age Psychiatry, Institute of Psychiatry, De Crespigny Park, London, UK
    Neuroimage 28:216-26. 2005
    ....
  9. ncbi request reprint The effect of filter size on VBM analyses of DT-MRI data
    Derek K Jones
    Neuroimaging Research Group, Centre for Neuroimaging Sciences, Institute of Psychiatry, London, UK
    Neuroimage 26:546-54. 2005
    ....
  10. doi request reprint Tests of pattern separation and pattern completion in humans-A systematic review
    Kathy Y Liu
    Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King s College London, London, United Kingdom
    Hippocampus 26:705-17. 2016
    ..The contribution of these parameters and other task design factors towards an optimal behavioral paradigm is discussed and recommendations for future research are made. © 2015 Wiley Periodicals, Inc. ..
  11. doi request reprint Psychotherapy and pharmacotherapy interventions to reduce distress or improve well-being in people with amyotrophic lateral sclerosis: A systematic review
    Rebecca L Gould
    a Department of Old Age Psychiatry, Institute of Psychiatry, King s College London, London, UK
    Amyotroph Lateral Scler Frontotemporal Degener 16:293-302. 2015
    ..Research is urgently needed to address these significant gaps in the literature. ..
  12. pmc Psychometric properties of multicomponent tools designed to assess frailty in older adults: A systematic review
    Jennifer L Sutton
    Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King s College London, Box PO70, De Crespigny Park, London, SE5 8AF, UK
    BMC Geriatr 16:55. 2016
    ....
  13. doi request reprint Interventions for reducing benzodiazepine use in older people: meta-analysis of randomised controlled trials
    Rebecca L Gould
    Rebecca L Gould, PhD, DClinPsy, King s College London, Department of Old Age Psychiatry, Institute of Psychiatry, London Mark C Coulson, PhD, Department of Psychology, School of Health and Education, Middlesex University, Hendon Natasha Patel, MBBS, Elizabeth Highton Williamson, Bsc, Robert J Howard, MD, King s College London, Department of Old Age Psychiatry, Institute of Psychiatry, London, UK
    Br J Psychiatry 204:98-107. 2014
    ..The use of benzodiazepines has been advised against in older people, but prevalence rates remain high...
  14. doi request reprint The importance of sustained attention in early Alzheimer's disease
    Jonathan D Huntley
    Institute of Psychiatry, Psychology and Neuroscience, King s College London, UK
    Int J Geriatr Psychiatry . 2016
    ..There is conflicting evidence regarding impairment of sustained attention in early Alzheimer's disease (AD). We examine whether sustained attention is impaired and predicts deficits in other cognitive domains in early AD...
  15. pmc Cognitive phenotype of psychotic symptoms in Alzheimer's disease: evidence for impaired visuoperceptual function in the misidentification subtype
    Suzanne J Reeves
    Department of Old Age Psychiatry, Institute of Psychiatry, King s College London, SE5 8AF, UK
    Int J Geriatr Psychiatry 30:1147-55. 2015
    ....
  16. doi request reprint Efficacy of cognitive behavioral therapy for anxiety disorders in older people: a meta-analysis and meta-regression of randomized controlled trials
    Rebecca L Gould
    Department of Old Age Psychiatry, Institute of Psychiatry, King s College London, UK
    J Am Geriatr Soc 60:218-29. 2012
    ..To review the magnitude and duration of and factors associated with effects of cognitive behavioral therapy (CBT) for anxiety disorders in older people...
  17. ncbi request reprint Task-induced deactivations during successful paired associates learning: an effect of age but not Alzheimer's disease
    Rebecca L Gould
    King s College London, MRC Centre for Neurodegeneration Research, Section of Old Age Psychiatry, Box P070, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Neuroimage 31:818-31. 2006
    ....
  18. ncbi request reprint Measuring disability in patients with neurodegenerative disease using the 'Yesterday Interview'
    Claire L Lomax
    Department of Psychology, Institute of Psychiatry, London, UK
    Int J Geriatr Psychiatry 19:1058-64. 2004
    ....
  19. ncbi request reprint A diffusion tensor magnetic resonance imaging study of frontal cortex connections in very-late-onset schizophrenia-like psychosis
    Derek K Jones
    Section on Tissue Biophysics and Biomimetics, National Institute of Child Health and Human Development NIH, Bethesda, MD 20892, USA
    Am J Geriatr Psychiatry 13:1092-9. 2005
    ..The authors looked within white-matter tracts, which mediate connectivity of the frontal lobes, in psychotic patients for evidence of loss of fiber integrity consistent with degenerative damage...
  20. ncbi request reprint Age effects on diffusion tensor magnetic resonance imaging tractography measures of frontal cortex connections in schizophrenia
    Derek K Jones
    Section on Tissue Biophysics and Biomimetics, LIMB, NICHD, National Institutes of Health, Bethesda, Maryland, USA
    Hum Brain Mapp 27:230-8. 2006
    ....
  21. ncbi request reprint The effect of ethnicity and gender on first-contact rates for schizophrenia-like psychosis in Bangladeshi, Black and White elders in Tower Hamlets, London
    Pamina R Mitter
    Oxford Mental Healthcare Trust, Oxford, UK
    Int J Geriatr Psychiatry 19:286-90. 2004
    ..This study investigates incident first contact rates in an area of East London with a high Bangladeshi population, to investigate if Bangladeshi-born elders also have an increased referral rate for SLP...