C J Burns

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Glucose-stimulated insulin secretion from rat islets of Langerhans is independent of mitogen-activated protein kinase activation
    C J Burns
    Biomedical Sciences Division, King s College London, United Kingdom
    Biochem Biophys Res Commun 239:447-50. 1997
  2. ncbi request reprint ERKs regulate cyclic AMP-induced steroid synthesis through transcription of the steroidogenic acute regulatory (StAR) gene
    S L Gyles
    Endocrinology and Reproduction Research Group and The Randall Centre, Guy's, King's and St. Thomas's School of Biomedical Sciences, King's College London, London SE1 1UL, United Kingdom
    J Biol Chem 276:34888-95. 2001
  3. ncbi request reprint Interdependence of steroidogenesis and shape changes in Y1 adrenocortical cells: studies with inhibitors of phosphoprotein phosphatases
    B J Whitehouse
    Endocrinology and Reproduction Research Group, GKT School of Biomedical Sciences, King s College London, Guy s Campus, London SE1 1UL, UK
    J Endocrinol 172:583-93. 2002
  4. ncbi request reprint Tetrahydrobenzothiophene inhibitors of hepatitis C virus NS5B polymerase
    M G LaPorte
    ViroPharma Incorporated, 397 Eagleview Boulevard, Exton, PA 19341, USA
    Bioorg Med Chem Lett 16:100-3. 2006

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Glucose-stimulated insulin secretion from rat islets of Langerhans is independent of mitogen-activated protein kinase activation
    C J Burns
    Biomedical Sciences Division, King s College London, United Kingdom
    Biochem Biophys Res Commun 239:447-50. 1997
    ..These results suggest that although MAPK may be activated by insulin secretagogues in adult rodent islets, this can be dissociated from the exocytotic release of insulin...
  2. ncbi request reprint ERKs regulate cyclic AMP-induced steroid synthesis through transcription of the steroidogenic acute regulatory (StAR) gene
    S L Gyles
    Endocrinology and Reproduction Research Group and The Randall Centre, Guy's, King's and St. Thomas's School of Biomedical Sciences, King's College London, London SE1 1UL, United Kingdom
    J Biol Chem 276:34888-95. 2001
    ..These observations suggest that the activation of ERK2/1 by increasing cAMP is an obligatory and regulated stage in the stimulation of steroid synthesis by cyclic AMP-generating stimuli...
  3. ncbi request reprint Interdependence of steroidogenesis and shape changes in Y1 adrenocortical cells: studies with inhibitors of phosphoprotein phosphatases
    B J Whitehouse
    Endocrinology and Reproduction Research Group, GKT School of Biomedical Sciences, King s College London, Guy s Campus, London SE1 1UL, UK
    J Endocrinol 172:583-93. 2002
    ....
  4. ncbi request reprint Tetrahydrobenzothiophene inhibitors of hepatitis C virus NS5B polymerase
    M G LaPorte
    ViroPharma Incorporated, 397 Eagleview Boulevard, Exton, PA 19341, USA
    Bioorg Med Chem Lett 16:100-3. 2006
    ..These compounds contain an appropriately substituted tetrahydrobenzothiophene scaffold. This communication will detail the SAR and activities of this series...