David J Collins

Summary

Affiliation: Institute of Cancer Research
Country: UK

Publications

  1. ncbi request reprint Bayesian estimation of pharmacokinetic parameters for DCE-MRI with a robust treatment of enhancement onset time
    Matthew R Orton
    Cancer Research UK Clinical MR Research Group, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey SM2 5PT, UK
    Phys Med Biol 52:2393-408. 2007
  2. doi request reprint Computationally efficient vascular input function models for quantitative kinetic modelling using DCE-MRI
    Matthew R Orton
    Cancer Research UK Clinical MR Research Group, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey SM2 5PT, UK
    Phys Med Biol 53:1225-39. 2008
  3. ncbi request reprint Dynamic magnetic resonance imaging of tumor perfusion. Approaches and biomedical challenges
    David J Collins
    Cancer Research UK Clinical Magnetic Resonance Research Group, Institute of Cancer Research and the Royal Marsden NHS Trust, Sutton, Surrey, United Kingdom
    IEEE Eng Med Biol Mag 23:65-83. 2004
  4. doi request reprint Quantitative mapping of hepatic perfusion index using MR imaging: a potential reproducible tool for assessing tumour response to treatment with the antiangiogenic compound BIBF 1120, a potent triple angiokinase inhibitor
    Keiko Miyazaki
    CRUK Clinical Magnetic Resonance Research Group, The Institute of Cancer Research, Royal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, UK
    Eur Radiol 18:1414-21. 2008
  5. doi request reprint Improved intravoxel incoherent motion analysis of diffusion weighted imaging by data driven Bayesian modeling
    Matthew R Orton
    CR UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research, Sutton, Surrey, UK
    Magn Reson Med 71:411-20. 2014
  6. doi request reprint A framework for optimization of diffusion-weighted MRI protocols for large field-of-view abdominal-pelvic imaging in multicenter studies
    Jessica M Winfield
    MRI Unit, Royal Marsden Hospital, Downs Road, Sutton, Surrey SM2 5PT, United Kingdom and Cancer Research UK Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research, 123 Old Brompton Road, London SW7 3RP, United Kingdom
    Med Phys 43:95. 2016
  7. doi request reprint MRI in the detection of prostate cancer: combined apparent diffusion coefficient, metabolite ratio, and vascular parameters
    Sophie F Riches
    CR UK and EPSRC Cancer Imaging Center, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, Sutton, Surrey SM2 5PT, United Kingdom
    AJR Am J Roentgenol 193:1583-91. 2009
  8. pmc Distortion correction of echo-planar diffusion-weighted images of uterine cervix
    Nandita M deSouza
    CRUK EPSRC Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey, UK
    J Magn Reson Imaging 43:1218-23. 2016
  9. pmc Separation of type and grade in cervical tumours using non-mono-exponential models of diffusion-weighted MRI
    Jessica M Winfield
    MRI Unit, The Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey, SM2 5PT, UK
    Eur Radiol . 2016
  10. pmc Assessment of treatment response by total tumor volume and global apparent diffusion coefficient using diffusion-weighted MRI in patients with metastatic bone disease: a feasibility study
    Matthew D Blackledge
    Radiotherapy and Imaging Division, Cancer Research UK and Engineering and Physical Sciences Research Council Cancer Imaging Centre at The Institute of Cancer Research and The Royal Marsden National Health Service Foundation Trust, Sutton, United Kingdom
    PLoS ONE 9:e91779. 2014

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Bayesian estimation of pharmacokinetic parameters for DCE-MRI with a robust treatment of enhancement onset time
    Matthew R Orton
    Cancer Research UK Clinical MR Research Group, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey SM2 5PT, UK
    Phys Med Biol 52:2393-408. 2007
    ..A more detailed method of assessing the uncertainty of the Bayesian approach is described, and the results show that this is a more accurate description of the estimation uncertainty...
  2. doi request reprint Computationally efficient vascular input function models for quantitative kinetic modelling using DCE-MRI
    Matthew R Orton
    Cancer Research UK Clinical MR Research Group, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey SM2 5PT, UK
    Phys Med Biol 53:1225-39. 2008
    ..These results were obtained from five example data sets, one of which was examined in more detail to compare the estimates obtained using the different models, and with literature values...
  3. ncbi request reprint Dynamic magnetic resonance imaging of tumor perfusion. Approaches and biomedical challenges
    David J Collins
    Cancer Research UK Clinical Magnetic Resonance Research Group, Institute of Cancer Research and the Royal Marsden NHS Trust, Sutton, Surrey, United Kingdom
    IEEE Eng Med Biol Mag 23:65-83. 2004
  4. doi request reprint Quantitative mapping of hepatic perfusion index using MR imaging: a potential reproducible tool for assessing tumour response to treatment with the antiangiogenic compound BIBF 1120, a potent triple angiokinase inhibitor
    Keiko Miyazaki
    CRUK Clinical Magnetic Resonance Research Group, The Institute of Cancer Research, Royal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, UK
    Eur Radiol 18:1414-21. 2008
    ..05). This pilot study demonstrates that HPI determined using quantified Gd-DTPA concentration is reproducible and may be useful for monitoring antiangiogenic treatment response of hepatic metastases...
  5. doi request reprint Improved intravoxel incoherent motion analysis of diffusion weighted imaging by data driven Bayesian modeling
    Matthew R Orton
    CR UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research, Sutton, Surrey, UK
    Magn Reson Med 71:411-20. 2014
    ..Use of a Bayesian shrinkage prior approach is, therefore, recommended for intravoxel incoherent motion modeling...
  6. doi request reprint A framework for optimization of diffusion-weighted MRI protocols for large field-of-view abdominal-pelvic imaging in multicenter studies
    Jessica M Winfield
    MRI Unit, Royal Marsden Hospital, Downs Road, Sutton, Surrey SM2 5PT, United Kingdom and Cancer Research UK Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research, 123 Old Brompton Road, London SW7 3RP, United Kingdom
    Med Phys 43:95. 2016
    ..5 T MR scanners from three manufacturers and assess repeatability of apparent diffusion coefficient (ADC) estimates in a temperature-controlled phantom and abdominal and pelvic organs in healthy volunteers...
  7. doi request reprint MRI in the detection of prostate cancer: combined apparent diffusion coefficient, metabolite ratio, and vascular parameters
    Sophie F Riches
    CR UK and EPSRC Cancer Imaging Center, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, Sutton, Surrey SM2 5PT, United Kingdom
    AJR Am J Roentgenol 193:1583-91. 2009
    ....
  8. pmc Distortion correction of echo-planar diffusion-weighted images of uterine cervix
    Nandita M deSouza
    CRUK EPSRC Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey, UK
    J Magn Reson Imaging 43:1218-23. 2016
    ..To investigate the clinical utility of the reverse gradient algorithm in correcting distortions in diffusion-weighted images of the cervix and for increasing diagnostic performance...
  9. pmc Separation of type and grade in cervical tumours using non-mono-exponential models of diffusion-weighted MRI
    Jessica M Winfield
    MRI Unit, The Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey, SM2 5PT, UK
    Eur Radiol . 2016
    ..Assessment of empirical diffusion-weighted MRI (DW-MRI) models in cervical tumours to investigate whether fitted parameters distinguish between types and grades of tumours...
  10. pmc Assessment of treatment response by total tumor volume and global apparent diffusion coefficient using diffusion-weighted MRI in patients with metastatic bone disease: a feasibility study
    Matthew D Blackledge
    Radiotherapy and Imaging Division, Cancer Research UK and Engineering and Physical Sciences Research Council Cancer Imaging Centre at The Institute of Cancer Research and The Royal Marsden National Health Service Foundation Trust, Sutton, United Kingdom
    PLoS ONE 9:e91779. 2014
    ..Semi-automatic segmentation of WBDWI is feasible for metastatic bone disease in this pilot cohort of 11 patients, and could be used to quantify tumor total diffusion volume and median global ADC for assessing response to treatment...
  11. doi request reprint Whole-body diffusion-weighted MR imaging for assessment of treatment response in myeloma
    Sharon L Giles
    From the Departments of Magnetic Resonance Imaging S L G, C M, D J C, V A M, C J S, N M D and Haemato oncology S W, F E D, G J M, Royal Marsden Hospital, Downs Rd, Sutton, Surrey SM2 5PT, England and Departments of Clinical Magnetic Resonance D J C, N M D and Molecular Pathology F E D, G J M, Institute of Cancer Research, Sutton, Surrey, England
    Radiology 271:785-94. 2014
    ..To determine the feasibility of whole-body diffusion-weighted (DW) magnetic resonance (MR) imaging for assessment of treatment response in myeloma...
  12. doi request reprint Comparison of free-breathing with navigator-controlled acquisition regimes in abdominal diffusion-weighted magnetic resonance images: Effect on ADC and IVIM statistics
    Neil P Jerome
    CR UK and EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, Institute of Cancer Research, Sutton, Surrey, UK
    J Magn Reson Imaging 39:235-40. 2014
    ..To evaluate the effect on diffusion-weighted image-derived parameters in the apparent diffusion coefficient (ADC) and intra-voxel incoherent motion (IVIM) models from choice of either free-breathing or navigator-controlled acquisition...
  13. doi request reprint Value of diffusion-weighted imaging for assessing site-specific response of advanced ovarian cancer to neoadjuvant chemotherapy: correlation of apparent diffusion coefficients with epithelial and stromal densities on histology
    Stavroula Kyriazi
    CR UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey, UK
    Cancer Biomark 7:201-10. 2010
    ..77, P< 0.001). There was no significant correlation between ADC and stromal density. Thus ADC reflects mainly epithelial content in advanced ovarian cancer and is not solely a function of lesion cellularity...
  14. doi request reprint Diagnostic accuracy of nodal enhancement pattern of rectal cancer at MRI enhanced with ultrasmall superparamagnetic iron oxide: findings in pathologically matched mesorectal lymph nodes
    Dow Mu Koh
    Department of Radiology, Royal Marsden Hospital, Sutton, Surrey SM2 5PT, United Kingdom
    AJR Am J Roentgenol 194:W505-13. 2010
    ....
  15. ncbi request reprint Reference tissue quantification of DCE-MRI data without a contrast agent calibration
    Simon Walker-Samuel
    Cancer Research UK Clinical Magnetic Resonance Research Group, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey, SM2 5NG, UK
    Phys Med Biol 52:589-601. 2007
    ..Both of these uncertainties are of the order of those associated with the conversion to Gd-DTPA concentration, according to literature estimates...
  16. doi request reprint Optimising diffusion-weighted imaging in the abdomen and pelvis: comparison of image quality between monopolar and bipolar single-shot spin-echo echo-planar sequences
    Stavroula Kyriazi
    CR UK and EPSRC Cancer Imaging Centre, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, Downs Road, Sutton, Surrey, SM2 5PT, UK
    Eur Radiol 20:2422-31. 2010
    ....
  17. pmc Diffusion-weighted MR neurography for the assessment of brachial plexopathy in oncological practice
    Adrian Andreou
    Department of Radiology, Royal Marsden, Sutton, Surrey, UK
    Cancer Imaging 15:6. 2015
    ..To evaluate diffusion-weighted MR neurography (DW-MRN) for visualizing the brachial plexus and for the assessment of brachial plexopathy...
  18. pmc Modelling DW-MRI data from primary and metastatic ovarian tumours
    Jessica M Winfield
    CRUK and EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK
    Eur Radiol 25:2033-40. 2015
    ..To assess goodness-of-fit and repeatability of mono-exponential, stretched exponential and bi-exponential models of diffusion-weighted MRI (DW-MRI) data in primary and metastatic ovarian cancer...
  19. doi request reprint Childhood extracranial neoplasms: the role of imaging in drug development and clinical trials
    Lucy A Fowkes
    Department of Radiology, Royal Marsden NHS Foundation Trust, Downs Road, Sutton, SM2 5PT, Surrey, UK
    Pediatr Radiol 45:1600-15. 2015
    ..The specific challenges of imaging in children, the potential for functional imaging techniques to inform upon and their inclusion in clinical trials are discussed...
  20. doi request reprint Stacked autoencoders for unsupervised feature learning and multiple organ detection in a pilot study using 4D patient data
    Hoo Chang Shin
    Institute of Cancer Rearch Royal Marsden NHS Foundation Trust, Sutton, United Kingdom
    IEEE Trans Pattern Anal Mach Intell 35:1930-43. 2013
    ....
  21. ncbi request reprint Diffusion-weighted MRI in the body: applications and challenges in oncology
    Dow Mu Koh
    Cancer Research UK Clinical Magnetic Resonance Research Group, Institute of Cancer Research, Sutton, Surrey, United Kingdom
    AJR Am J Roentgenol 188:1622-35. 2007
    ..The challenges to widespread adoption of the technique for cancer imaging in the body are discussed...
  22. ncbi request reprint Measurements of occupational exposure to switched gradient and spatially-varying magnetic fields in areas adjacent to 1.5 T clinical MRI systems
    Sophie F Riches
    Cancer Research UK Clinical Magnetic Resonance Research Group, Royal Marsden NHS Trust and Institute of Cancer Research, Surrey, UK
    J Magn Reson Imaging 26:1346-52. 2007
    ..5 T magnetic resonance imaging (MRI) scanners during image acquisition and when moving in the spatially-varying static magnetic field is compliant with European Union (EU) Directive 2004/40/EC (the Directive)...
  23. ncbi request reprint Informatics in Radiology (infoRAD): Magnetic Resonance Imaging Workbench: analysis and visualization of dynamic contrast-enhanced MR imaging data
    James A d'Arcy
    Cancer Research UK Clinical MR Research Group, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey, United Kingdom SM2 5PT
    Radiographics 26:621-32. 2006
    ..MRIW is written in IDL, enabling it to be used on a variety of computer systems...
  24. ncbi request reprint Design and development of a prototype endocavitary probe for high-intensity focused ultrasound delivery with integrated magnetic resonance imaging
    Iain P Wharton
    Therapeutic Ultrasound, Joint Department of Physics, The Institute of Cancer Research, Sutton, Surrey, UK
    J Magn Reson Imaging 25:548-56. 2007
    ..To integrate a high intensity focused ultrasound (HIFU) transducer with an MR receiver coil for endocavitary MR-guided thermal ablation of localized pelvic lesions...
  25. ncbi request reprint Practical aspects of assessing tumors using clinical diffusion-weighted imaging in the body
    Dow Mu Koh
    CR UK Clinical Magnetic Resonance Research Group, Institute of Cancer Research and Academic Department of Radiology, Royal Marsden Hospital, Sutton, UK
    Magn Reson Med Sci 6:211-24. 2007
    ..We illustrate the potential use of these techniques to detect and characterize tumors and to monitor treatment effects...
  26. pmc Quantitative assessment of the hepatic pharmacokinetics of the antimicrobial sitafloxacin in humans using in vivoF magnetic resonance spectroscopy
    Geoffrey S Payne
    Cancer Research UK Clinical Magnetic Resonance Research Group, The Institute of Cancer Research and Royal Marsden NHS Trust, Sutton, Surrey, UK
    Br J Clin Pharmacol 59:244-8. 2005
    ..To measure hepatic concentrations of the fluorine-containing antimicrobial, sitafloxacin, using in vivo(19)F magnetic resonance spectroscopy (MRS)...
  27. ncbi request reprint Localized COSY and DQF-COSY 1H-MRS sequences for investigating human tibial bone marrow in vivo and initial application to patients with acute leukemia
    Andrew P Prescot
    Cancer Research UK Clinical Magnetic Resonance Research Group, Institute of Cancer Research, Sutton, Surrey, UK
    J Magn Reson Imaging 22:541-8. 2005
    ..To develop 2D 1H-MRS measurement sequences for the evaluation of bone marrow lipids, and to assess these measurement sequences in healthy and diseased bone marrow...
  28. ncbi request reprint Dynamic MRI for imaging tumor microvasculature: comparison of susceptibility and relaxivity techniques in pelvic tumors
    Katharine J Lankester
    Department of Medical Oncology, Mount Vernon Hospital, Northwood, Middlesex, UK
    J Magn Reson Imaging 25:796-805. 2007
    ....
  29. doi request reprint Technology insight: water diffusion MRI--a potential new biomarker of response to cancer therapy
    Daniel M Patterson
    Department of Medical Oncology, Mount Vernon Hospital, Northwood, UK
    Nat Clin Pract Oncol 5:220-33. 2008
    ..The strength of evidence for adoption of DW-MRI as a biomarker for the assessment of tumor response is presented...
  30. ncbi request reprint Human gallbladder bile: noninvasive investigation in vivo with single-voxel 1H MR spectroscopy
    Andrew P Prescot
    Cancer Research UK Clinical Magnetic Resonance Research Group, Institute of Cancer Research, Surrey, England, UK
    Radiology 229:587-92. 2003
    ..8) were within the expected range of levels in human bile. Findings in this preliminary investigation indicate that human gallbladder bile can be qualitatively and quantitatively studied noninvasively with 1H MR spectroscopy...