Jessica K R Boult

Summary

Affiliation: Institute of Cancer Research
Country: UK

Publications

  1. pmc A multi-parametric imaging investigation of the response of C6 glioma xenografts to MLN0518 (tandutinib) treatment
    Jessica K R Boult
    Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden NHS Trust, Sutton, Surrey, United Kingdom
    PLoS ONE 8:e63024. 2013
  2. doi request reprint Exploring ΔR(2) * and ΔR(1) as imaging biomarkers of tumor oxygenation
    Jake S Burrell
    Division of Radiotherapy and Imaging, The Institute of Cancer Research, Sutton, Surrey, SM2 5NG, United Kingdom
    J Magn Reson Imaging 38:429-34. 2013
  3. doi request reprint Evaluation of novel combined carbogen USPIO (CUSPIO) imaging biomarkers in assessing the antiangiogenic effects of cediranib (AZD2171) in rat C6 gliomas
    Jake S Burrell
    Cancer Research UK and EPSRC Cancer Imaging Centre, The Institute of Cancer Research, Sutton, Surrey, United Kingdom
    Int J Cancer 131:1854-62. 2012
  4. pmc MRI measurements of vessel calibre in tumour xenografts: comparison with vascular corrosion casting
    Jake S Burrell
    CR UK and EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research, 15 Cotswold Road Sutton, Surrey, SM2 5NG, UK
    Microvasc Res 84:323-9. 2012
  5. doi request reprint Evaluation and immunohistochemical qualification of carbogen-induced ΔR₂ as a noninvasive imaging biomarker of improved tumor oxygenation
    Lauren C J Baker
    Cancer Research UK and EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Surrey, UK
    Int J Radiat Oncol Biol Phys 87:160-7. 2013
  6. doi request reprint Non-invasive in vivo imaging of vessel calibre in orthotopic prostate tumour xenografts
    Simon Walker-Samuel
    Cancer Research UK and EPSRC Cancer Imaging Centre, The Institute of Cancer Research and Royal Marsden NHS Trust, Sutton, Surrey, United Kingdom
    Int J Cancer 130:1284-93. 2012
  7. doi request reprint Improving apparent diffusion coefficient estimates and elucidating tumor heterogeneity using Bayesian adaptive smoothing
    Simon Walker-Samuel
    Cancer Research UK and EPSRC Cancer Imaging Centre, The Institute of Cancer Research, Sutton, Surrey, United Kingdom
    Magn Reson Med 65:438-47. 2011
  8. pmc Exploring the biomechanical properties of brain malignancies and their pathologic determinants in vivo with magnetic resonance elastography
    Yann Jamin
    Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden NHS Trust, London, United Kingdom
    Cancer Res 75:1216-24. 2015
  9. pmc Evaluation of clinically translatable MR imaging biomarkers of therapeutic response in the TH-MYCN transgenic mouse model of neuroblastoma
    Yann Jamin
    Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, 15 Cotswold Road, Sutton, Surrey SM2 5NG, England
    Radiology 266:130-40. 2013
  10. pmc Model free approach to kinetic analysis of real-time hyperpolarized 13C magnetic resonance spectroscopy data
    Deborah K Hill
    Cancer Research UK CR UK and Engineering and Physical Sciences Research Council EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden NHS Trust, Sutton, Surrey, United Kingdom
    PLoS ONE 8:e71996. 2013

Collaborators

Detail Information

Publications12

  1. pmc A multi-parametric imaging investigation of the response of C6 glioma xenografts to MLN0518 (tandutinib) treatment
    Jessica K R Boult
    Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden NHS Trust, Sutton, Surrey, United Kingdom
    PLoS ONE 8:e63024. 2013
    ..This study highlights the challenges of identifying appropriate quantitative imaging response biomarkers in heterogeneous models, particularly considering the multifaceted roles of angiogenic growth factors...
  2. doi request reprint Exploring ΔR(2) * and ΔR(1) as imaging biomarkers of tumor oxygenation
    Jake S Burrell
    Division of Radiotherapy and Imaging, The Institute of Cancer Research, Sutton, Surrey, SM2 5NG, United Kingdom
    J Magn Reson Imaging 38:429-34. 2013
    ..To investigate the combined use of hyperoxia-inducedΔR(2) * and ΔR(1) as a noninvasive imaging biomarker of tumor hypoxia...
  3. doi request reprint Evaluation of novel combined carbogen USPIO (CUSPIO) imaging biomarkers in assessing the antiangiogenic effects of cediranib (AZD2171) in rat C6 gliomas
    Jake S Burrell
    Cancer Research UK and EPSRC Cancer Imaging Centre, The Institute of Cancer Research, Sutton, Surrey, United Kingdom
    Int J Cancer 131:1854-62. 2012
    ..Such biomarkers may prove effective in longitudinally monitoring tumor vascular remodeling and/or evasive resistance in response to antiangiogenic therapy...
  4. pmc MRI measurements of vessel calibre in tumour xenografts: comparison with vascular corrosion casting
    Jake S Burrell
    CR UK and EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research, 15 Cotswold Road Sutton, Surrey, SM2 5NG, UK
    Microvasc Res 84:323-9. 2012
    ..The strong association between the in vivo MRI and post mortem μCT values supports the use of R(v) as an imaging biomarker in clinical trials of investigational vascular targeted therapies...
  5. doi request reprint Evaluation and immunohistochemical qualification of carbogen-induced ΔR₂ as a noninvasive imaging biomarker of improved tumor oxygenation
    Lauren C J Baker
    Cancer Research UK and EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Surrey, UK
    Int J Radiat Oncol Biol Phys 87:160-7. 2013
    ..To evaluate and histologically qualify carbogen-induced ΔR2 as a noninvasive magnetic resonance imaging biomarker of improved tumor oxygenation using a double 2-nitroimidazole hypoxia marker approach...
  6. doi request reprint Non-invasive in vivo imaging of vessel calibre in orthotopic prostate tumour xenografts
    Simon Walker-Samuel
    Cancer Research UK and EPSRC Cancer Imaging Centre, The Institute of Cancer Research and Royal Marsden NHS Trust, Sutton, Surrey, United Kingdom
    Int J Cancer 130:1284-93. 2012
    ....
  7. doi request reprint Improving apparent diffusion coefficient estimates and elucidating tumor heterogeneity using Bayesian adaptive smoothing
    Simon Walker-Samuel
    Cancer Research UK and EPSRC Cancer Imaging Centre, The Institute of Cancer Research, Sutton, Surrey, United Kingdom
    Magn Reson Med 65:438-47. 2011
    ..A novel measure of tumor ADC heterogeneity was also defined, which identified differences between tumors derived from different cell lines, which were reflected in histological variations within the tissue microenvironment...
  8. pmc Exploring the biomechanical properties of brain malignancies and their pathologic determinants in vivo with magnetic resonance elastography
    Yann Jamin
    Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden NHS Trust, London, United Kingdom
    Cancer Res 75:1216-24. 2015
    ..Our findings reinforce the case for MRE use in diagnosing and staging brain malignancies, based on the association of different tumor phenotypes with different mechanical properties. Cancer Res; 75(7); 1216-24. ©2015 AACR. ..
  9. pmc Evaluation of clinically translatable MR imaging biomarkers of therapeutic response in the TH-MYCN transgenic mouse model of neuroblastoma
    Yann Jamin
    Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, 15 Cotswold Road, Sutton, Surrey SM2 5NG, England
    Radiology 266:130-40. 2013
    ..To evaluate noninvasive and clinically translatable magnetic resonance (MR) imaging biomarkers of therapeutic response in the TH-MYCN transgenic mouse model of aggressive, MYCN-amplified neuroblastoma...
  10. pmc Model free approach to kinetic analysis of real-time hyperpolarized 13C magnetic resonance spectroscopy data
    Deborah K Hill
    Cancer Research UK CR UK and Engineering and Physical Sciences Research Council EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden NHS Trust, Sutton, Surrey, United Kingdom
    PLoS ONE 8:e71996. 2013
    ....
  11. doi request reprint Investigating temporal fluctuations in tumor vasculature with combined carbogen and ultrasmall superparamagnetic iron oxide particle (CUSPIO) imaging
    Jake S Burrell
    Cancer Research UK and EPSRC Cancer Imaging Centre, The Institute of Cancer Research, Belmont, Sutton, Surrey, United Kingdom
    Magn Reson Med 66:227-34. 2011
    ..Combining ΔR(2)*(carbogen) and ΔR(2)*(USPIO) with a novel segmentation scheme can facilitate the interpretation of susceptibility contrast MRI data and enable a deeper interrogation of tumor vascular function and architecture...
  12. doi request reprint Bayesian estimation of changes in transverse relaxation rates
    Simon Walker-Samuel
    Cancer Research UK and EPSRC Cancer Imaging Centre, The Institute of Cancer Research, Sutton, Surrey, United Kingdom
    Magn Reson Med 64:914-21. 2010
    ....