- APC in the regulation of intestinal crypt fissionH S Wasan
Cancer and Immunogenetics Laboratory, John Radcliffe Hospital, Headington, Oxford, U K
J Pathol 185:246-55. 1998..It is concluded that in vivo, the major defect in pre-neoplastic intestine harbouring APC mutations is elevated rates of crypt fission, and that this is also the mode by which micro-adenomas enlarge...
- Dietary fat influences on polyp phenotype in multiple intestinal neoplasia miceH S Wasan
Imperial Cancer Research Fund Cancer and Immunogenetics Laboratory, John Radcliffe Hospital, Headington, Oxford, United Kingdom
Proc Natl Acad Sci U S A 94:3308-13. 1997..A further understanding of the biology of this interaction may provide novel strategies aimed at both colonic polyp prevention and treatment...