P F Sumariwalla

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. pmc Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis
    Pei Jin
    Receptor BioLogix, Inc, Palo Alto, CA 94303, USA
    Arthritis Res Ther 10:R73. 2008
  2. doi request reprint Antagonism of the human epidermal growth factor receptor family controls disease severity in murine collagen-induced arthritis
    Percy F Sumariwalla
    Kennedy Institute of Rheumatology Division, Faculty of Medicine, Imperial College London, London, UK
    Arthritis Rheum 58:3071-80. 2008
  3. doi request reprint Suppression of tumour necrosis factor production from mononuclear cells by a novel synthetic compound, CLX-090717
    P F Sumariwalla
    Kennedy Institute of Rheumatology, Imperial College London, London, UK
    Rheumatology (Oxford) 48:32-8. 2009
  4. pmc P-selectin glycoprotein ligand 1 therapy ameliorates established collagen-induced arthritis in DBA/1 mice partly through the suppression of tumour necrosis factor
    P F Sumariwalla
    Kennedy Institute of Rheumatology, Imperial College London, UK
    Clin Exp Immunol 136:67-75. 2004
  5. pmc The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
    A M Malfait
    Kennedy Institute of Rheumatology, Hammersmith, London, United Kingdom
    Proc Natl Acad Sci U S A 97:9561-6. 2000

Collaborators

Detail Information

Publications5

  1. pmc Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis
    Pei Jin
    Receptor BioLogix, Inc, Palo Alto, CA 94303, USA
    Arthritis Res Ther 10:R73. 2008
    ..The objective of the present study was to identify alternative splice variants (ASV) from cell surface receptor genes, and to determine whether the novel proteins encoded exert therapeutic activity in an in vivo model of arthritis...
  2. doi request reprint Antagonism of the human epidermal growth factor receptor family controls disease severity in murine collagen-induced arthritis
    Percy F Sumariwalla
    Kennedy Institute of Rheumatology Division, Faculty of Medicine, Imperial College London, London, UK
    Arthritis Rheum 58:3071-80. 2008
    ..To evaluate the therapeutic potential of the human epidermal growth factor receptor (HER) family inhibitor, herstatin, in an animal model of arthritis...
  3. doi request reprint Suppression of tumour necrosis factor production from mononuclear cells by a novel synthetic compound, CLX-090717
    P F Sumariwalla
    Kennedy Institute of Rheumatology, Imperial College London, London, UK
    Rheumatology (Oxford) 48:32-8. 2009
    ..To evaluate the clinical efficacy of a novel synthetic peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist, CLX-090717, in several in vitro cell culture systems and murine CIA, an experimental model of RA...
  4. pmc P-selectin glycoprotein ligand 1 therapy ameliorates established collagen-induced arthritis in DBA/1 mice partly through the suppression of tumour necrosis factor
    P F Sumariwalla
    Kennedy Institute of Rheumatology, Imperial College London, UK
    Clin Exp Immunol 136:67-75. 2004
    ..The mechanism of action involves reduced cellularity of synovium as anticipated, along with a reduction in TNF production from inflammatory cells in the synovium. The latter mechanism needs further mechanistic analysis...
  5. pmc The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
    A M Malfait
    Kennedy Institute of Rheumatology, Hammersmith, London, United Kingdom
    Proc Natl Acad Sci U S A 97:9561-6. 2000
    ..Taken together, these data show that CBD, through its combined immunosuppressive and anti-inflammatory actions, has a potent anti-arthritic effect in CIA...