M Maze

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. doi request reprint G-protein-coupled receptors
    R D Sanders
    Academic Anaesthetics, Imperial College, Chelsea and Westminster Hospital, 369 Fulham Road, London, SW10 9NH, UK
    Handb Exp Pharmacol . 2008
  2. ncbi request reprint New agents for sedation in the intensive care unit
    M Maze
    Sir Ivan Magill Department of Anaesthetics and Intensive Care, Division of Surgery, Anaesthetics, and Intensive Care, Imperial College School of Medicine, Chelsea and Westminster Hospital, London, United Kingdom
    Crit Care Clin 17:881-97. 2001
  3. doi request reprint Dexmedetomidine provides cortical neuroprotection: impact on anaesthetic-induced neuroapoptosis in the rat developing brain
    R D Sanders
    Magill Department of Anaesthetics, Pain Medicine and Intensive Care, Imperial College London, Chelsea and Westminster Hospital, London, UK
    Acta Anaesthesiol Scand 54:710-6. 2010
  4. doi request reprint The glutaminergic, GABAergic, dopaminergic but not cholinergic neurons are susceptible to anaesthesia-induced cell death in the rat developing brain
    Z W Zhou
    Section of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital, London SW10 9NH, UK
    Neuroscience 174:64-70. 2011
  5. ncbi request reprint Asynchronous administration of xenon and hypothermia significantly reduces brain infarction in the neonatal rat
    J L Martin
    Department of Anaesthetics, Pain Medicine, and Intensive Care, Imperial College London, London, UK
    Br J Anaesth 98:236-40. 2007
  6. doi request reprint Xenon preconditioning confers neuroprotection regardless of gender in a mouse model of transient middle cerebral artery occlusion
    V Limatola
    Department of Anaesthetics, Pain Medicine and Intensive Care, Imperial College London, Chelsea and Westminster Hospital, London, UK
    Neuroscience 165:874-81. 2010
  7. doi request reprint Balancing paediatric anaesthesia: preclinical insights into analgesia, hypnosis, neuroprotection, and neurotoxicity
    R D Sanders
    Department of Anaesthetics, Pain Medicine and Intensive Care, Faculty of Medicine, Imperial College London, London, UK
    Br J Anaesth 101:597-609. 2008
  8. pmc Xenon treatment protects against cold ischemia associated delayed graft function and prolongs graft survival in rats
    H Zhao
    Department of Surgery and Cancer, Section of Anaesthetics, Pain Medicine and Intensive Care, Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital, London, UK
    Am J Transplant 13:2006-18. 2013
  9. ncbi request reprint Isoflurane exerts antinociceptive and hypnotic properties at all ages in Fischer rats
    R D Sanders
    Department of Anaesthetics and Intensive Care, Faculty of Medicine, Imperial College, London, UK
    Br J Anaesth 95:393-9. 2005
  10. doi request reprint Peripheral orthopaedic surgery down-regulates hippocampal brain-derived neurotrophic factor and impairs remote memory in mouse
    A R Fidalgo
    Anaesthesia, Pain Medicine and Intensive Care Section, Department of Surgery and Cancer, Chelsea and Westminster Hospital, Imperial College School of Medicine, 369 Fulham Road, London SW10 9NH, UK
    Neuroscience 190:194-9. 2011

Collaborators

  • D Ma
  • R D Sanders
  • M Li
  • F Cavaliere
  • D Cattano
  • A J T George
  • H Zhao
  • Z W Zhou
  • A R Fidalgo
  • V Limatola
  • J L Martin
  • N P Franks
  • J M Weller
  • L E Nelson
  • M Chong
  • H Huang
  • P H Maxwell
  • H R Watts
  • C Tralau-Stewart
  • Y Shu
  • C Pac-Soo
  • L Benzonana
  • F Noormohamed
  • M Cibelli
  • I Nagy
  • J P M White
  • X Guo
  • F Giunta
  • J Gu
  • P Ward
  • T Z Guo
  • M Hossain
  • J Xu
  • P P Lakhlani
  • M Bloch
  • J Durbridge
  • S Young
  • K Haire
  • S Oyesola
  • J Wyner
  • T Walker
  • D Newble
  • D Dob
  • C B Saper
  • J Lu
  • L E Limbird
  • D M Lovinger
  • L B MacMillan
  • B A McCool

Detail Information

Publications15

  1. doi request reprint G-protein-coupled receptors
    R D Sanders
    Academic Anaesthetics, Imperial College, Chelsea and Westminster Hospital, 369 Fulham Road, London, SW10 9NH, UK
    Handb Exp Pharmacol . 2008
    ..In this review we discuss the relevant molecular and neural network pharmacology of anesthetic agents acting at G-protein-coupled receptors...
  2. ncbi request reprint New agents for sedation in the intensive care unit
    M Maze
    Sir Ivan Magill Department of Anaesthetics and Intensive Care, Division of Surgery, Anaesthetics, and Intensive Care, Imperial College School of Medicine, Chelsea and Westminster Hospital, London, United Kingdom
    Crit Care Clin 17:881-97. 2001
    ..Lorazepam seems to be finding more proponents, especially in long-term ICU sedation where the costs of the newer agents may be prohibitive...
  3. doi request reprint Dexmedetomidine provides cortical neuroprotection: impact on anaesthetic-induced neuroapoptosis in the rat developing brain
    R D Sanders
    Magill Department of Anaesthetics, Pain Medicine and Intensive Care, Imperial College London, Chelsea and Westminster Hospital, London, UK
    Acta Anaesthesiol Scand 54:710-6. 2010
    ..Recent evidence has demonstrated the anti-apoptotic of dexmedetomidine in different brain injury models. Herein, we investigated whether dexmedetomidine could directly protect against cortical injury in vitro and in vivo...
  4. doi request reprint The glutaminergic, GABAergic, dopaminergic but not cholinergic neurons are susceptible to anaesthesia-induced cell death in the rat developing brain
    Z W Zhou
    Section of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital, London SW10 9NH, UK
    Neuroscience 174:64-70. 2011
    ..Our data suggests, anaesthetic exposure significantly increases neuroapoptosis of glutamatergic, GABAergic and dopaminergic neurons in the developing brain but not that of the cholinergic neurons in the basal forebrain...
  5. ncbi request reprint Asynchronous administration of xenon and hypothermia significantly reduces brain infarction in the neonatal rat
    J L Martin
    Department of Anaesthetics, Pain Medicine, and Intensive Care, Imperial College London, London, UK
    Br J Anaesth 98:236-40. 2007
    ..This study sought to investigate whether asynchronous administration of xenon and hypothermia is capable of combining synergistically to provide neuroprotection...
  6. doi request reprint Xenon preconditioning confers neuroprotection regardless of gender in a mouse model of transient middle cerebral artery occlusion
    V Limatola
    Department of Anaesthetics, Pain Medicine and Intensive Care, Imperial College London, Chelsea and Westminster Hospital, London, UK
    Neuroscience 165:874-81. 2010
    ..HIF-1alpha and phospho-Akt were quantitatively upregulated in both sexes. Our data suggested that xenon preconditioning improved histological and neurological functional outcome in both gender in a stroke model of mice...
  7. doi request reprint Balancing paediatric anaesthesia: preclinical insights into analgesia, hypnosis, neuroprotection, and neurotoxicity
    R D Sanders
    Department of Anaesthetics, Pain Medicine and Intensive Care, Faculty of Medicine, Imperial College London, London, UK
    Br J Anaesth 101:597-609. 2008
    ..We review the current state of preclinical research in paediatric anaesthesia and identify areas which require further exploration in order to provide the foundations for well-conducted clinical trials...
  8. pmc Xenon treatment protects against cold ischemia associated delayed graft function and prolongs graft survival in rats
    H Zhao
    Department of Surgery and Cancer, Section of Anaesthetics, Pain Medicine and Intensive Care, Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital, London, UK
    Am J Transplant 13:2006-18. 2013
    ..Our data suggest that xenon treatment attenuates DGF and enhances graft survival. This approach could be translated into clinical practice leading to a considerable improvement in long-term graft survival. ..
  9. ncbi request reprint Isoflurane exerts antinociceptive and hypnotic properties at all ages in Fischer rats
    R D Sanders
    Department of Anaesthetics and Intensive Care, Faculty of Medicine, Imperial College, London, UK
    Br J Anaesth 95:393-9. 2005
    ..We investigated whether a similar time dependency existed for the responses to the volatile anaesthetic isoflurane...
  10. doi request reprint Peripheral orthopaedic surgery down-regulates hippocampal brain-derived neurotrophic factor and impairs remote memory in mouse
    A R Fidalgo
    Anaesthesia, Pain Medicine and Intensive Care Section, Department of Surgery and Cancer, Chelsea and Westminster Hospital, Imperial College School of Medicine, 369 Fulham Road, London SW10 9NH, UK
    Neuroscience 190:194-9. 2011
    ..Our data suggest that a reduction in the level of hippocampal BDNF and an increase in the level of hippocampal IL-1β following surgery may affect the transference of fear memory in the mouse brain...
  11. ncbi request reprint Xenon: no stranger to anaesthesia
    R D Sanders
    Department of Anaesthetics and Intensive Care, Faculty of Medicine, Imperial College London, UK
    Br J Anaesth 91:709-17. 2003
  12. ncbi request reprint Evaluation of high fidelity patient simulator in assessment of performance of anaesthetists
    J M Weller
    Department of Surgery, Wellington School of Medicine, Otago University, Private Bag 7343, Wellington South, New Zealand
    Br J Anaesth 90:43-7. 2003
    ..We set out to assess the reliability of a global rating scale for scoring simulator performance in crisis management...
  13. ncbi request reprint Neuroprotective and neurotoxic properties of the 'inert' gas, xenon
    D Ma
    Magill Department of Anaesthesia, Chelsea and Westminster Hospital and Biophysics Group, The Blackett Laboratory, Imperial College of Science, Technology and Medicine, London, UK
    Br J Anaesth 89:739-46. 2002
    ....
  14. ncbi request reprint The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway
    L E Nelson
    Department of Anaesthetics and Intensive Care, Chelsea and Westminster Hospital, Imperial College School of Medicine, London SW10 9NH, UK
    Nat Neurosci 5:979-84. 2002
    ..We conclude that the TMN is a discrete neural locus that has a key role in the sedative response to GABAergic anesthetics...
  15. pmc Substitution of a mutant alpha2a-adrenergic receptor via "hit and run" gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses in vivo
    P P Lakhlani
    Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA
    Proc Natl Acad Sci U S A 94:9950-5. 1997
    ....