Clive J Hoggart

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. pmc A risk model for lung cancer incidence
    Clive Hoggart
    Department of Epidemiology and Biostatistics, Imperial College London, St Mary s Campus, Paddington, London, United Kingdom
    Cancer Prev Res (Phila) 5:834-46. 2012
  2. pmc Fine-scale estimation of location of birth from genome-wide single-nucleotide polymorphism data
    Clive J Hoggart
    Department of Epidemiology and Biostatistics, Imperial College, London W2 1PG, United Kingdom
    Genetics 190:669-77. 2012
  3. pmc Sequence-level population simulations over large genomic regions
    Clive J Hoggart
    Department of Epidemiology and Public Health, Imperial College, London W2 1PG, United Kingdom
    Genetics 177:1725-31. 2007
  4. doi request reprint Genome-wide significance for dense SNP and resequencing data
    Clive J Hoggart
    Department of Epidemiology and Public Health, Imperial College London, Norfolk Place, London, UK
    Genet Epidemiol 32:179-85. 2008
  5. pmc Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies
    Clive J Hoggart
    Department of Epidemiology and Public Health, Imperial College, London, United Kingdom
    PLoS Genet 4:e1000130. 2008
  6. pmc Fregene: simulation of realistic sequence-level data in populations and ascertained samples
    Marc Chadeau-Hyam
    Department of Epidemiology and Public Health, Imperial College, St Mary s Campus, Norfolk Place, London, W2 1PG, UK
    BMC Bioinformatics 9:364. 2008
  7. pmc Genome-wide association study reveals multiple loci associated with primary tooth development during infancy
    Demetris Pillas
    Department of Epidemiology and Public Health, Imperial College London, London, United Kingdom
    PLoS Genet 6:e1000856. 2010
  8. doi request reprint invertFREGENE: software for simulating inversions in population genetic data
    Paul F O'Reilly
    Department of Epidemiology and Biostatistics, Imperial College
    Bioinformatics 26:838-40. 2010
  9. doi request reprint Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children
    Jethro A Herberg
    Section of Paediatrics, Division of Infectious Diseases, Department of Medicine, Imperial College London, London, United Kingdom
    JAMA 316:835-45. 2016
  10. pmc MultiPhen: joint model of multiple phenotypes can increase discovery in GWAS
    Paul F O'Reilly
    Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom
    PLoS ONE 7:e34861. 2012

Detail Information

Publications16

  1. pmc A risk model for lung cancer incidence
    Clive Hoggart
    Department of Epidemiology and Biostatistics, Imperial College London, St Mary s Campus, Paddington, London, United Kingdom
    Cancer Prev Res (Phila) 5:834-46. 2012
    ..Our model is generalizable and straightforward to implement. Its accuracy can be attributed to its modeling of lifetime exposure to smoking...
  2. pmc Fine-scale estimation of location of birth from genome-wide single-nucleotide polymorphism data
    Clive J Hoggart
    Department of Epidemiology and Biostatistics, Imperial College, London W2 1PG, United Kingdom
    Genetics 190:669-77. 2012
    ..A method with such accuracy is potentially valuable in population genetics and forensics...
  3. pmc Sequence-level population simulations over large genomic regions
    Clive J Hoggart
    Department of Epidemiology and Public Health, Imperial College, London W2 1PG, United Kingdom
    Genetics 177:1725-31. 2007
    ....
  4. doi request reprint Genome-wide significance for dense SNP and resequencing data
    Clive J Hoggart
    Department of Epidemiology and Public Health, Imperial College London, Norfolk Place, London, UK
    Genet Epidemiol 32:179-85. 2008
    ..We compare our results for sequence data to those derived by the HapMap Consortium and find notable differences which may be due to the small sample sizes used in the HapMap estimate...
  5. pmc Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies
    Clive J Hoggart
    Department of Epidemiology and Public Health, Imperial College, London, United Kingdom
    PLoS Genet 4:e1000130. 2008
    ....
  6. pmc Fregene: simulation of realistic sequence-level data in populations and ascertained samples
    Marc Chadeau-Hyam
    Department of Epidemiology and Public Health, Imperial College, St Mary s Campus, Norfolk Place, London, W2 1PG, UK
    BMC Bioinformatics 9:364. 2008
    ..We describe here main functionalities of both FREGENE and SAMPLE, a companion program that can replicate association study datasets...
  7. pmc Genome-wide association study reveals multiple loci associated with primary tooth development during infancy
    Demetris Pillas
    Department of Epidemiology and Public Health, Imperial College London, London, United Kingdom
    PLoS Genet 6:e1000856. 2010
    ..Genes at four of the identified loci are implicated in the development of cancer. A variant within the HOXB gene cluster associated with occlusion defects requiring orthodontic treatment by age 31 years...
  8. doi request reprint invertFREGENE: software for simulating inversions in population genetic data
    Paul F O'Reilly
    Department of Epidemiology and Biostatistics, Imperial College
    Bioinformatics 26:838-40. 2010
    ..We describe previously unreported signatures of inversions in SNP data observed in invertFREGENE results and a known inversion in humans...
  9. doi request reprint Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children
    Jethro A Herberg
    Section of Paediatrics, Division of Infectious Diseases, Department of Medicine, Imperial College London, London, United Kingdom
    JAMA 316:835-45. 2016
    ..Because clinical features do not reliably distinguish bacterial from viral infection, many children worldwide receive unnecessary antibiotic treatment, while bacterial infection is missed in others...
  10. pmc MultiPhen: joint model of multiple phenotypes can increase discovery in GWAS
    Paul F O'Reilly
    Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom
    PLoS ONE 7:e34861. 2012
    ....
  11. pmc The effect of genomic inversions on estimation of population genetic parameters from SNP data
    Nafisa Katrin Seich Al Basatena
    Department of Immunology, Imperial College London, London W2 1PG, United Kingdom
    Genetics 193:243-53. 2013
    ....
  12. doi request reprint Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways
    Hariklia Eleftherohorinou
    Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, London W2 1PG, UK
    Hum Mol Genet 20:3494-506. 2011
    ....
  13. doi request reprint Predicting IVIG resistance in UK Kawasaki disease
    Sarah Davies
    Department of Paediatric Infectious Diseases, St Mary s Hospital, Imperial College Healthcare NHS Trust, London, UK
    Arch Dis Child 100:366-8. 2015
    ..The KS does not predict IVIG resistance or CAA in our population. This highlights the need for biomarkers to identify children at increased risk of CAA, and to select patients for anti-inflammatory treatment in addition to IVIG. ..
  14. pmc Assessing the relative ages of admixture in the bovine hybrid zones of Africa and the Near East using X chromosome haplotype mosaicism
    Abigail R Freeman
    Smurfit Institute of Genetics, Trinity Colege, Dublin, Ireland
    Genetics 173:1503-10. 2006
    ....
  15. pmc Control of confounding of genetic associations in stratified populations
    Clive J Hoggart
    Epidemiology Unit, London School of Hygiene and Tropical Medicine, Umited Kingdom
    Am J Hum Genet 72:1492-1504. 2003
    ..With only 32 markers informative for ancestry, the efficiency of the analysis is 70%. These methods can deal with both confounding and selection bias in genetic-association studies, making family-based designs unnecessary...
  16. ncbi request reprint Skin pigmentation, biogeographical ancestry and admixture mapping
    Mark D Shriver
    Department of Anthropology, Penn State University, 409 Carpenter Bld, University Park, PA 16802, USA
    Hum Genet 112:387-99. 2003
    ..The implications and applications of ancestry estimates in biomedical research are discussed...