Julie Fox

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. doi request reprint Epidemiology of non-B clade forms of HIV-1 in men who have sex with men in the UK
    Julie Fox
    Department of HIV, Guys and St Thomas NHS Trust Kings College London, St Thomas Hospital, London, UK
    AIDS 24:2397-401. 2010
  2. ncbi request reprint Transmitted drug-resistant HIV-1 in primary HIV-1 infection; incidence, evolution and impact on response to antiretroviral therapy
    J Fox
    Department of Infectious Diseases, Imperial College, London, UK
    HIV Med 7:477-83. 2006
  3. doi request reprint Reductions in HIV transmission risk behaviour following diagnosis of primary HIV infection: a cohort of high-risk men who have sex with men
    Julie Fox
    Department of Genitourinary Medicine and Infectious Disease, Clinical Trials Centre, Winston ChurchillBuilding, Imperial College London, St Mary s Hospital Campus, London W2 1PG, UK
    HIV Med 10:432-8. 2009
  4. pmc Human immunodeficiency virus (HIV)-specific T helper responses fail to predict CD4+ T cell decline following short-course treatment at primary HIV-1 infection
    J Fox
    Department of Genitourinary Medicine and Infectious Disease, Division of Medicine, Wright Fleming Institute, Imperial College London, London, UK
    Clin Exp Immunol 152:532-7. 2008
  5. ncbi request reprint Risk of HIV transmission in discordant partners
    Julie Fox
    Imperial College London, UK
    J HIV Ther 12:48-53. 2007
  6. pmc How safe is safer sex? High levels of HSV-1 and HSV-2 in female sex workers in London
    J Fox
    Department of Genitourinary Medicine and Infectious Disease, Imperial College London, UK
    Epidemiol Infect 134:1114-9. 2006
  7. ncbi request reprint Slower CD4 cell decline following cessation of a 3 month course of HAART in primary HIV infection: findings from an observational cohort
    Sarah Fidler
    Imperial College, St Mary s Hospital, London, UK
    AIDS 21:1283-91. 2007
  8. pmc Virological blips and predictors of post treatment viral control after stopping ART started in Primary HIV infection
    Sarah Fidler
    1Department of Genitourinary Medicine and Infectious Disease, Imperial College, London, UK 2University College London, London, UK 3Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, CH 4Guys and St Thomas Hospital NHS Trust, Westminster Bridge Road, London SE1 7EH, UK 5Clinical and Epidemiological Sciences, FHI 360, Durham, NC, USA 6Department of Internal Medicine, Hospital Universitari Germans Trias i Pujol, Badalona, Spain 7 Peter Medawar Building for Pathogen Research, Nuffield Dept of Medicine, Oxford University, UK Oxford Martin School, Oxford, UK Oxford NIHR Biomedical Research Centre, Oxford, UK
    J Acquir Immune Defic Syndr . 2016
  9. ncbi request reprint Comparative potency of three antiretroviral therapy regimes in primary HIV infection
    Sarah Fidler
    Department of GUM and Communicable Diseases, Wright Fleming Institute, Jefferiss Trust Laboratories, London, UK
    AIDS 20:247-52. 2006
  10. doi request reprint Primary HIV infection: to treat or not to treat?
    Sarah Fidler
    Department of GUM and HIV, Division of Medicine, Imperial College, UK
    Curr Opin Infect Dis 21:4-10. 2008

Detail Information

Publications25

  1. doi request reprint Epidemiology of non-B clade forms of HIV-1 in men who have sex with men in the UK
    Julie Fox
    Department of HIV, Guys and St Thomas NHS Trust Kings College London, St Thomas Hospital, London, UK
    AIDS 24:2397-401. 2010
    ..To describe the frequency and risk factors of non-B HIV-1 subtypes in men who have sex with men (MSM) in the UK...
  2. ncbi request reprint Transmitted drug-resistant HIV-1 in primary HIV-1 infection; incidence, evolution and impact on response to antiretroviral therapy
    J Fox
    Department of Infectious Diseases, Imperial College, London, UK
    HIV Med 7:477-83. 2006
    ....
  3. doi request reprint Reductions in HIV transmission risk behaviour following diagnosis of primary HIV infection: a cohort of high-risk men who have sex with men
    Julie Fox
    Department of Genitourinary Medicine and Infectious Disease, Clinical Trials Centre, Winston ChurchillBuilding, Imperial College London, St Mary s Hospital Campus, London W2 1PG, UK
    HIV Med 10:432-8. 2009
    ..We explored the potential impact on HIV transmission-risk behaviour of PHI diagnosis in men who have sex with men (MSM)...
  4. pmc Human immunodeficiency virus (HIV)-specific T helper responses fail to predict CD4+ T cell decline following short-course treatment at primary HIV-1 infection
    J Fox
    Department of Genitourinary Medicine and Infectious Disease, Division of Medicine, Wright Fleming Institute, Imperial College London, London, UK
    Clin Exp Immunol 152:532-7. 2008
    ..Long-term (>3 years) preservation of virus-specific CD4+ cells occurred in 45% of patients receiving SCART in PHI. There was no correlation between either the presence or magnitude of these responses and clinical outcome...
  5. ncbi request reprint Risk of HIV transmission in discordant partners
    Julie Fox
    Imperial College London, UK
    J HIV Ther 12:48-53. 2007
  6. pmc How safe is safer sex? High levels of HSV-1 and HSV-2 in female sex workers in London
    J Fox
    Department of Genitourinary Medicine and Infectious Disease, Imperial College London, UK
    Epidemiol Infect 134:1114-9. 2006
    ..Sex workers are candidates for HSV vaccine efficacy or intervention studies...
  7. ncbi request reprint Slower CD4 cell decline following cessation of a 3 month course of HAART in primary HIV infection: findings from an observational cohort
    Sarah Fidler
    Imperial College, St Mary s Hospital, London, UK
    AIDS 21:1283-91. 2007
    ..To investigate the effect of a short course of HAART during primary HIV infection (PHI) on rate of CD4 cell and viral load change...
  8. pmc Virological blips and predictors of post treatment viral control after stopping ART started in Primary HIV infection
    Sarah Fidler
    1Department of Genitourinary Medicine and Infectious Disease, Imperial College, London, UK 2University College London, London, UK 3Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, CH 4Guys and St Thomas Hospital NHS Trust, Westminster Bridge Road, London SE1 7EH, UK 5Clinical and Epidemiological Sciences, FHI 360, Durham, NC, USA 6Department of Internal Medicine, Hospital Universitari Germans Trias i Pujol, Badalona, Spain 7 Peter Medawar Building for Pathogen Research, Nuffield Dept of Medicine, Oxford University, UK Oxford Martin School, Oxford, UK Oxford NIHR Biomedical Research Centre, Oxford, UK
    J Acquir Immune Defic Syndr . 2016
    ..Few individuals commencing antiretroviral therapy (ART) in primary HIV infection (PHI) maintain undetectable viraemia following treatment cessation. Associated factors remain unclear given the importance of the phenomenon to cure research...
  9. ncbi request reprint Comparative potency of three antiretroviral therapy regimes in primary HIV infection
    Sarah Fidler
    Department of GUM and Communicable Diseases, Wright Fleming Institute, Jefferiss Trust Laboratories, London, UK
    AIDS 20:247-52. 2006
    ..To best achieve the most rapid reduction in primary viraemia we compared three different ART regimens in PHI...
  10. doi request reprint Primary HIV infection: to treat or not to treat?
    Sarah Fidler
    Department of GUM and HIV, Division of Medicine, Imperial College, UK
    Curr Opin Infect Dis 21:4-10. 2008
    ..The aim of this article is to review new data on the use of antiretroviral therapy in primary HIV infection...
  11. ncbi request reprint Prevalence of primary genotypic resistance in a UK centre: Comparison of primary HIV-1 and newly diagnosed treatment-naive individuals
    Julie Fox
    St Mary s Hospital, London, UK
    AIDS 21:237-9. 2007
    ..Variations in the prevalence of TrDR-HIV-1 may reflect the heterogeneity of methodologies and definitions used for resistance...
  12. ncbi request reprint The clinical implications of antiretroviral pharmacogenomics
    Julie Fox
    St Mary s Hospital, Clinical Trials Centre, Winston Churchill Wing, Division of Medicine, Imperial College London, Praed Street, London W2 1NY, UK
    Pharmacogenomics 7:587-96. 2006
    ..This review summarizes the key findings in the growing knowledge between human genetics and response to antiretroviral drugs and how these findings may be effectively applied in a clinical context...
  13. doi request reprint Sexual transmission of HIV-1
    Julie Fox
    Department of HIV, Faculty of Medicine, Harrison Unit, Lambeth Wing, Guys and St Thomas NHS Trust Kings College London, Westminster Bridge Road, London, UK
    Antiviral Res 85:276-85. 2010
    ..This article forms part of a special issue of Antiviral Research marking the 25th anniversary of antiretroviral drug discovery and development, Vol 85, issue 1, 2010...
  14. doi request reprint An overview of the relative risks of different sexual behaviours on HIV transmission
    Olamide Dosekun
    Guys and St Thomas NHS Trust, London, UK
    Curr Opin HIV AIDS 5:291-7. 2010
    ..0005-0.0026 per coital act. The risk of acquiring HIV from a single contact varies enormously and is dependant upon the infectiousness of the HIV-positive individual and the susceptibility to HIV of their sexual partner...
  15. pmc The importance of viral blips and duration of therapy initiated in primary infection in maintaining viral control after stopping cART
    Sarah Fidler
    Department of Genitourinary Medicine and Infectious Diseases, Imperial College, London, UK
    J Int AIDS Soc 17:19820. 2014
    ..This analysis aims to investigate the effect of cART duration and the rate of viral blips while on cART initiated in PHI, and other factors on maintaining viral control for those stopping cART...
  16. pmc Brief Report: Enhanced Normalization of CD4/CD8 Ratio With Earlier Antiretroviral Therapy at Primary HIV Infection
    John Thornhill
    Department of Medicine, Imperial College, London, United Kingdom Medical Research Council Clinical Trials Unit, University College London, London, United Kingdom Medical Research Council Uganda Virus Research Institute Research Unit on AIDS, Entebbe, Uganda Kirby Institute University of New South Wales and Centre for Applied Medical Research, St Vincent s Hospital, Sydney, Australia HIV Prevention Unit, Medical Research Council, Durban, South Africa Projeto Pra├ža Onze, Hospital Escola Sao Francisco de Assis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil Division of Infectious Diseases, Ospedale San Raffaele, Milan, Italy Department of HIV, Faculty of Medicine, Guys and St Thomas NHS Trust Kings College London, United Kingdom and Hospital Clinic IDIBAPS, University of Barcelona, Barcelona, Spain
    J Acquir Immune Defic Syndr 73:69-73. 2016
    ..Despite antiretroviral therapy (ART), recovery of CD4/CD8 ratio in chronic HIV infection is incomplete; we hypothesize enhanced CD4/CD8 ratio recovery with earlier treatment initiation in recently infected individuals...
  17. doi request reprint Primary HIV infection: a medical and public health emergency requiring rapid specialist management
    Sarah Fidler
    Imperial College London, London, UK
    Clin Med (Lond) 16:180-3. 2016
    ..This paper summarises the presentation and management of PHI, incorporating current research and guideline changes and discusses the role of PHI in onward transmission. ..
  18. doi request reprint Raltegravir-induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome - implications for clinical practice and patient safety
    Melissa E O Perry
    Department of Genito Urinary Medicine, Guys and St Thomas NHS Foundation Trust, London, UK
    Int J STD AIDS 24:639-42. 2013
    ..Clinicians should be aware of raltegravir-induced DRESS syndrome as well as the potential for drug-drug interactions due to protease inhibitor-based therapy...
  19. pmc Sexual transmission of single human immunodeficiency virus type 1 virions encoding highly polymorphic multisite cytotoxic T-lymphocyte escape variants
    Anita Milicic
    The Peter Medawar Building for Pathogen Research and The James Martin 21st Century School, Nuffield Department of Clinical Medicine, University of Oxford, South Parks Road, Oxford OX1 3SY, United Kingdom
    J Virol 79:13953-62. 2005
    ..In donors who are themselves controlling an early, acute infection, the precise timing of onward transmission is a crucial determinant of the viral variants available to compose the inoculum...
  20. pmc HIV-1-specific CD4+ T lymphocyte turnover and activation increase upon viral rebound
    Thomas J Scriba
    Peter Medawar Building for Pathogen Research and Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom
    J Clin Invest 115:443-50. 2005
    ..The turnover of these virus-specific cells increased and they adopted an effector phenotype when viremia returned...
  21. doi request reprint Increasing incidence of acute hepatitis C in individuals diagnosed with primary HIV in the United Kingdom
    Julie Fox
    AIDS 22:666-8. 2008
  22. ncbi request reprint Development and evaluation of a real-time nucleic acid sequence based amplification assay for rapid detection of influenza A
    Catherine Moore
    Wales Specialist Virology Centre, NPHS Microbiology Cardiff, University Hospital of Wales, Cardiff, United Kingdom
    J Med Virol 74:619-28. 2004
    ..In conclusion, the real-time influenza A assay demonstrated clinical usefulness in both hospital and community populations...
  23. ncbi request reprint Ultrasensitive detection and phenotyping of CD4+ T cells with optimized HLA class II tetramer staining
    Thomas J Scriba
    The Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom
    J Immunol 175:6334-43. 2005
    ..These cells would not be detectable with normal flow-cytometric techniques...
  24. doi request reprint An unusual abacavir reaction
    Julie Fox
    AIDS 22:1520-2. 2008
  25. ncbi request reprint Sex in the suburbs
    Julie Fox
    St Mary s Hospital, Paddington, London, United Kingdom
    Aust Fam Physician 32:358-63. 2003
    ..Many suburban sexual health clinics exist in Australasia. However, sexual health research has hitherto been restricted to populations from major metropolitan centres...