Matthew C Fisher
Affiliation: Imperial College
- Proteomic and phenotypic profiling of the amphibian pathogen Batrachochytrium dendrobatidis shows that genotype is linked to virulenceMatthew C Fisher
Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Hospital, Norfolk Place, London W21PG, UK
Mol Ecol 18:415-29. 2009..We argue that future studies need to clarify the mechanism(s) and rate at which Bd is evolving, and the impact that such variation has on the host-pathogen dynamic...
- Emerging fungal threats to animal, plant and ecosystem healthMatthew C Fisher
Department of Infectious Disease Epidemiology, Imperial College, London W2 1PG, UK
Nature 484:186-94. 2012..We argue that nascent fungal infections will cause increasing attrition of biodiversity, with wider implications for human and ecosystem health, unless steps are taken to tighten biosecurity worldwide...
- Sex, drugs and recombination: the wild life of AspergillusMatthew C Fisher
Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, UK
Mol Ecol 21:1305-6. 2012....
- Endemic and introduced haplotypes of Batrachochytrium dendrobatidis in Japanese amphibians: sink or source?Matthew C Fisher
Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London W21PG, UK
Mol Ecol 18:4731-3. 2009..Their results show that Bd is widely prevalent in native species across Japan in at least three of the islands that make up the archipelago, proving for the first time that Asia harbours Bd...
- Multilocus microsatellite typing system for Penicillium marneffei reveals spatially structured populationsMatthew C Fisher
Department of Infectious Disease Epidemiology, Imperial College Faculty of Medicine, London W2 1PG, UK
J Clin Microbiol 42:5065-9. 2004..multilocus.net/); this provides a powerful epidemiological tool for analyzing the underlying parameters that are responsible for the emergence of P. marneffei in human immunodeficiency virus-positive populations...
- Context-dependent amphibian host population response to an invading pathogenBenjamin J Doddington
Department of Infectious Disease Epidemiology, Imperial College, London W2 1PG, United Kingdom
Ecology 94:1795-804. 2013..Our results illustrate the need to take into account the appropriate environmental scale and context when assessing the risk that an emerging pathogen presents to a naive population or species...
- Chromosomal copy number variation, selection and uneven rates of recombination reveal cryptic genome diversity linked to pathogenicityRhys A Farrer
The Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
PLoS Genet 9:e1003703. 2013....
- Multiple emergences of genetically diverse amphibian-infecting chytrids include a globalized hypervirulent recombinant lineageRhys A Farrer
Department Infectious Disease Epidemiology, Imperial College, London W2 1PG, United Kingdom
Proc Natl Acad Sci U S A 108:18732-6. 2011....
- Factors driving pathogenicity vs. prevalence of amphibian panzootic chytridiomycosis in IberiaSusan F Walker
Department of Infectious Disease Epidemiology, Imperial College London W2 1PG, UK
Ecol Lett 13:372-82. 2010..This study demonstrates the power of combining surveillance and molecular data to ascertain the drivers of new emerging infections diseases...
- Global emergence of Batrachochytrium dendrobatidis and amphibian chytridiomycosis in space, time, and hostMatthew C Fisher
Department of Infectious Disease Epidemiology, St Mary s Hospital, Imperial College, London W2 1PG, United
Annu Rev Microbiol 63:291-310. 2009..We then consider the major host and pathogen factors that have led to the occurrence of chytridiomycosis in amphibian species, populations, and communities...
- Expression profiling the temperature-dependent amphibian response to infection by Batrachochytrium dendrobatidisLaia Ribas
Department of Infectious Disease Epidemiology, Imperial College London, UK
PLoS ONE 4:e8408. 2009..This study demonstrates the temperature-dependency of the amphibian response to infection by Bd and indicates the influence that changing climates may exert on the ectothermic host response to pathogens...
- Persistence of the emerging pathogen Batrachochytrium dendrobatidis outside the amphibian host greatly increases the probability of host extinctionKate M Mitchell
Department of Infectious Disease Epidemiology, Imperial College, Norfolk Place, London W2 1PG, UK
Proc Biol Sci 275:329-34. 2008..Although this model is able to predict clear trends, more precise predictions will only be possible when the life history of B. dendrobatidis, including free-living stages of the life cycle, is better understood...
- Epidemiological and genetic analysis of severe acute respiratory syndromeChristl A Donnelly
Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, UK
Lancet Infect Dis 4:672-83. 2004....
- Environmental detection of Batrachochytrium dendrobatidis in a temperate climateSusan F Walker
Department of Infectious Disease Epidemiology, Imperial College, St Mary s Campus, Norfolk Place, London W2 1PG, UK
Dis Aquat Organ 77:105-12. 2007..Our results emphasise the need to further investigate the life cycle of B. dendrobatidis to more completely understand the epidemiology of this emerging pathogen...
- Clonality despite sex: the evolution of host-associated sexual neighborhoods in the pathogenic fungus Penicillium marneffeiDaniel A Henk
Department of Infectious Disease Epidemiology, Imperial College, Norfolk Place, London, United Kingdom
PLoS Pathog 8:e1002851. 2012..marneffei overlap with three different bamboo rat host distributions suggesting that recombination within hosts may act to maintain population barriers within P. marneffei...
- Low diversity Cryptococcus neoformans variety grubii multilocus sequence types from Thailand are consistent with an ancestral African originSitali P Simwami
Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, United Kingdom
PLoS Pathog 7:e1001343. 2011..96 - 27,177.76). Further high-density sampling of global Cng STs is now necessary to resolve the temporal sequence underlying the global emergence of this human pathogen...
- Using false discovery rates to benchmark SNP-callers in next-generation sequencing projectsRhys A Farrer
Department of Infectious Disease Epidemiology, St Mary s Hospital, Imperial College London, London, UK
Sci Rep 3:1512. 2013..We benchmark this method against other SNP callers using our FDR method with three fungal genomes, finding that it was able achieve a high level of accuracy. These tools are available at http://cfdr.sourceforge.net/...
- The gut fungus Basidiobolus ranarum has a large genome and different copy numbers of putatively functionally redundant elongation factor genesDaniel A Henk
The Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
PLoS ONE 7:e31268. 2012..This suggests that gene or genome duplication may be an important feature of B. ranarum evolution, and also suggests that B. ranarum may have mechanisms in place that favor the preservation of functionally overlapping genes...
- Genetic diversity, recombination, and divergence in animal associated Penicillium dipodomyisDaniel A Henk
Department of Infectious Disease Epidemiology, Imperial College, London, United Kingdom
PLoS ONE 6:e22883. 2011..dipodomyis lineage diverged from closely related species also found in cheek pouches of Kangaroo Rats and their stored seeds about 11 million years ago, a similar divergence time as Dipodomys from its sister rodent taxa...
- Chytrid fungus in EuropeTrenton W J Garner
Emerg Infect Dis 11:1639-41. 2005
- The emerging amphibian pathogen Batrachochytrium dendrobatidis globally infects introduced populations of the North American bullfrog, Rana catesbeianaTrenton W J Garner
Institute of Zoology, Zoological Society of London, Regent s Park, London NW1 4RY, UK
Biol Lett 2:455-9. 2006..These factors taken together with our study suggest that the global threat of B. dendrobatidis disease transmission posed by bullfrogs is significant...
- Invasive pathogens threaten species recovery programsSusan F Walker
Curr Biol 18:R853-4. 2008
- Penicillium marneffei infection and recent advances in the epidemiology and molecular biology aspectsNongnuch Vanittanakom
Department of Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand
Clin Microbiol Rev 19:95-110. 2006..Future investigations pertaining to the roles of these genes in host-fungus interactions may provide the key knowledge to understanding the pathogenicity of P. marneffei...
- Climate change and outbreaks of amphibian chytridiomycosis in a montane area of Central Spain; is there a link?Jaime Bosch
Departamento de Biodiversidad y Biologia Evolutiva, Museo Nacional de Ciencias Naturales, CSIC, José Gutiérrez Abascal, 2 28006 Madrid, Spain
Proc Biol Sci 274:253-60. 2007....
- Role of Cannomys badius as a natural animal host of Penicillium marneffei in IndiaHarish Gugnani
Department of Medical Mycology, University of Delhi, India
J Clin Microbiol 42:5070-5. 2004..This demonstrates the utility of an MLMT-based approach to elucidating the epidemiology of P. marneffei...
- Isolation and identification of the human pathogen Pythium insidiosum from environmental samples collected in Thai agricultural areasJidapa Supabandhu
Department of Microbiology Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand
Med Mycol 46:41-52. 2008..insidiosum infection for individuals working in endemic agricultural areas...
- Fungal multilocus sequence typing--it's not just for bacteriaJohn W Taylor
Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720 3102, USA
Curr Opin Microbiol 6:351-6. 2003..mode can help answer questions common to all emerging diseases: is the disease due to the recent spread of a pathogen, to the emergence of a virulent strain of an existing pathogen, or to a change in the environment that promotes disease?..