Frances M Cowan

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi The internal capsule in neonatal imaging
    Frances M Cowan
    Department of Paediatrics, Imperial College, Hammersmith Hospital, London, UK
    Semin Fetal Neonatal Med 10:461-74. 2005
  2. doi Antepartum and intrapartum factors preceding neonatal hypoxic-ischemic encephalopathy
    Miriam Martinez-Biarge
    MRCPCH, Department of Paediatrics, 5 Floor, Hammersmith House, Hammersmith Hospital, DuCane Rd, London W12 OHS, United Kingdom
    Pediatrics 132:e952-9. 2013
  3. pmc Pilot randomized trial of therapeutic hypothermia with serial cranial ultrasound and 18-22 month follow-up for neonatal encephalopathy in a low resource hospital setting in Uganda: study protocol
    Nicola J Robertson
    Institute for Women s Health, 86 96 Chenies Mews, University College London, London, UK
    Trials 12:138. 2011
  4. pmc Neonatal ECMO Study of Temperature (NEST)--a randomised controlled trial
    David J Field
    Department of Heath Science, Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester, UK
    BMC Pediatr 10:24. 2010
  5. ncbi Origin and timing of brain lesions in term infants with neonatal encephalopathy
    Frances Cowan
    Department of Paediatrics, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK
    Lancet 361:736-42. 2003
  6. pmc Does cranial ultrasound imaging identify arterial cerebral infarction in term neonates?
    F Cowan
    Department of Paediatrics and Neonatal Medicine, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
    Arch Dis Child Fetal Neonatal Ed 90:F252-6. 2005
  7. doi Specific relations between neurodevelopmental abilities and white matter microstructure in children born preterm
    Serena J Counsell
    Imaging Sciences Department, Robert Steiner MR Unit, Imperial College London, Hammersmith Hospital, London, UK
    Brain 131:3201-8. 2008
  8. doi White matter and cortical injury in hypoxic-ischemic encephalopathy: antecedent factors and 2-year outcome
    Miriam Martinez-Biarge
    Department of Pediatrics and Imaging Sciences, Imperial College, Hammersmith Hospital Campus, London, United Kingdom
    J Pediatr 161:799-807. 2012
  9. ncbi Thalamo-cortical connectivity in children born preterm mapped using probabilistic magnetic resonance tractography
    Serena J Counsell
    Robert Steiner MR Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, DuCane Road, London, W12 0HS, UK
    Neuroimage 34:896-904. 2007
  10. doi Prediction of neurodevelopmental outcome after hypoxic-ischemic encephalopathy treated with hypothermia by diffusion tensor imaging analyzed using tract-based spatial statistics
    Nora Tusor
    Centre for the Developing Brain, Imperial College and MRC Clinical Sciences Centre, Hammersmith Hospital, London, UK
    Pediatr Res 72:63-9. 2012

Collaborators

Detail Information

Publications49

  1. ncbi The internal capsule in neonatal imaging
    Frances M Cowan
    Department of Paediatrics, Imperial College, Hammersmith Hospital, London, UK
    Semin Fetal Neonatal Med 10:461-74. 2005
    ..Future studies will assess the relevance of these findings not only for motor outcome but also for cognitive, visual and sensory abilities...
  2. doi Antepartum and intrapartum factors preceding neonatal hypoxic-ischemic encephalopathy
    Miriam Martinez-Biarge
    MRCPCH, Department of Paediatrics, 5 Floor, Hammersmith House, Hammersmith Hospital, DuCane Rd, London W12 OHS, United Kingdom
    Pediatrics 132:e952-9. 2013
    ..To determine whether antepartum factors alone, intrapartum factors alone, or both in combination, are associated with term neonatal hypoxic-ischemic encephalopathy (HIE)...
  3. pmc Pilot randomized trial of therapeutic hypothermia with serial cranial ultrasound and 18-22 month follow-up for neonatal encephalopathy in a low resource hospital setting in Uganda: study protocol
    Nicola J Robertson
    Institute for Women s Health, 86 96 Chenies Mews, University College London, London, UK
    Trials 12:138. 2011
    ..However, the greatest burden of perinatal asphyxia falls in low and mid-resource settings where it is unclear whether therapeutic hypothermia is safe and effective...
  4. pmc Neonatal ECMO Study of Temperature (NEST)--a randomised controlled trial
    David J Field
    Department of Heath Science, Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester, UK
    BMC Pediatr 10:24. 2010
    ..Infants allocated to the control group will receive ECMO at 37 degrees C throughout their course, which is currently standard practice around the world. Health status of both groups will be assessed formally at 2 years corrected age...
  5. ncbi Origin and timing of brain lesions in term infants with neonatal encephalopathy
    Frances Cowan
    Department of Paediatrics, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK
    Lancet 361:736-42. 2003
    ..However, there is no evidence that brain damage occurs before birth. We aimed to test the hypothesis that neonatal encephalopathy, early neonatal seizures, or both result from early antenatal insults...
  6. pmc Does cranial ultrasound imaging identify arterial cerebral infarction in term neonates?
    F Cowan
    Department of Paediatrics and Neonatal Medicine, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
    Arch Dis Child Fetal Neonatal Ed 90:F252-6. 2005
    ..To evaluate the diagnostic accuracy of cranial ultrasound (CUS) for detection of neonatal arterial territory cerebral infarction in term infants...
  7. doi Specific relations between neurodevelopmental abilities and white matter microstructure in children born preterm
    Serena J Counsell
    Imaging Sciences Department, Robert Steiner MR Unit, Imperial College London, Hammersmith Hospital, London, UK
    Brain 131:3201-8. 2008
    ..FA may aid prognostication and provide a biomarker for therapeutic or mechanistic studies of preterm brain injury...
  8. doi White matter and cortical injury in hypoxic-ischemic encephalopathy: antecedent factors and 2-year outcome
    Miriam Martinez-Biarge
    Department of Pediatrics and Imaging Sciences, Imperial College, Hammersmith Hospital Campus, London, United Kingdom
    J Pediatr 161:799-807. 2012
    ..To examine the spectrum of isolated white matter (WM)/cortical injury and its relation to outcomes in infants with hypoxic-ischemic encephalopathy (HIE) and normal appearing basal ganglia and thalami...
  9. ncbi Thalamo-cortical connectivity in children born preterm mapped using probabilistic magnetic resonance tractography
    Serena J Counsell
    Robert Steiner MR Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, DuCane Road, London, W12 0HS, UK
    Neuroimage 34:896-904. 2007
    ..This technique promises to be a useful tool for assessing connectivity in the developing brain and in infants with lesions...
  10. doi Prediction of neurodevelopmental outcome after hypoxic-ischemic encephalopathy treated with hypothermia by diffusion tensor imaging analyzed using tract-based spatial statistics
    Nora Tusor
    Centre for the Developing Brain, Imperial College and MRC Clinical Sciences Centre, Hammersmith Hospital, London, UK
    Pediatr Res 72:63-9. 2012
    ....
  11. ncbi Natural history of brain lesions in extremely preterm infants studied with serial magnetic resonance imaging from birth and neurodevelopmental assessment
    Leigh E Dyet
    Department of Paediatrics, Medical Research Council Clinical Sciences Centre, Imperial College, Hammersmith Campus, London, United Kingdom
    Pediatrics 118:536-48. 2006
    ....
  12. doi Patterns of brain injury in neonates exposed to perinatal sentinel events
    Akudo Okereafor
    Department of Paediatrics and Neonatal Medicine, Hammersmith Hospital, Du Cane Rd, London, W12 OHS, United Kingdom
    Pediatrics 121:906-14. 2008
    ....
  13. ncbi Axial and radial diffusivity in preterm infants who have diffuse white matter changes on magnetic resonance imaging at term-equivalent age
    Serena J Counsell
    Imaging Sciences Department, MRC Clinical Sciences Centre, London, United Kingdom
    Pediatrics 117:376-86. 2006
    ....
  14. doi Feeding and communication impairments in infants with central grey matter lesions following perinatal hypoxic-ischaemic injury
    Miriam Martinez-Biarge
    Department of Paediatrics and Imaging Sciences, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom
    Eur J Paediatr Neurol 16:688-96. 2012
    ..However there is no equivalent predictive data for other specific outcomes. Feeding and communication impairments are also common in children following hypoxic-ischaemic encephalopathy (HIE) and BGT injury...
  15. doi Patterns of cerebral injury and neurodevelopmental outcomes after symptomatic neonatal hypoglycemia
    Charlotte M Burns
    Department of Paediatrics, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, England
    Pediatrics 122:65-74. 2008
    ..Brain injury patterns identified on early MRI scans and their relationships to the nature of the hypoglycemic insult and neurodevelopmental outcomes are poorly defined...
  16. ncbi Structural linear measurements in the newborn brain: accuracy of cranial ultrasound compared to MRI
    Lara M Leijser
    Department of Paediatrics, Hammersmith Hospital, Imperial College, Du Cane Road, London W12 OHS, UK
    Pediatr Radiol 37:640-8. 2007
    ..Cranial ultrasonography (cUS) is the primary method used for evaluating the neonatal brain and it is important to know whether linear measurements made using this technique are accurate...
  17. ncbi The effect of preterm birth on neonatal cerebral vasculature studied with magnetic resonance angiography at 3 Tesla
    Christina Malamateniou
    Robert Steiner MRI Unit, Imaging Sciences Department, Hammersmith Hospital Campus, Imperial College London, London, UK
    Neuroimage 32:1050-9. 2006
    ....
  18. doi Frequently encountered cranial ultrasound features in the white matter of preterm infants: correlation with MRI
    Lara M Leijser
    Department of Paediatrics, Imaging Science Department, Clinical Sciences Centre, Hammersmith Hospital, Imperial College, London, UK
    Eur J Paediatr Neurol 13:317-26. 2009
    ..Bilateral symmetrical echogenic and echolucent areas in the white matter are frequently seen on the cranial ultrasound scans of apparently well preterm infants without overt pathology...
  19. doi Implementation and Operational Research: Cohort Analysis of Program Data to Estimate HIV Incidence and Uptake of HIV-Related Services Among Female Sex Workers in Zimbabwe, 2009-2014
    James R Hargreaves
    Centre for Evaluation, London School of Hygiene and Tropical Medicine, London, United Kingdom Centre for Sexual Health and HIV AIDS Research CeSHHAR Zimbabwe, Harare, Zimbabwe United Nations Population Fund, New York, NY Women s Global Health Imperative, RTI International, San Francisco, CA Gesellschaft für Internationale Zusammenarbeit, Bonn, Germany National AIDS Council, Harare, Zimbabwe AIDS and TB Unit, Ministry of Health and Child Care, Harare, Zimbabwe and Research Department for Infection and Population Health, University College London, London, United Kingdom
    J Acquir Immune Defic Syndr 72:e1-8. 2016
    ..HIV epidemiology and intervention uptake among female sex workers (FSW) in sub-Saharan Africa remain poorly understood. Data from outreach programs are a neglected resource...
  20. pmc 'How poor are you?' -- a comparison of four questionnaire delivery modes for assessing socio-economic position in rural zimbabwe
    Sophie J S Pascoe
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 8:e74977. 2013
    ..This paper reports on results of a trial of four QDMs, and the effect of mode on poverty reporting...
  21. doi Neurodevelopmental outcome in children with congenital heart disease
    Miriam Martinez-Biarge
    Department of Paediatrics, Hammersmith Hospital, Imperial College, London, UK
    Semin Fetal Neonatal Med 18:279-85. 2013
    ..Long-term neurodevelopmental follow-up of children with CHD is warranted for early identification of and intervention for difficulties. ..
  22. doi Development of the optic radiations and visual function after premature birth
    Michela Groppo
    Centre for the Developing Brain, Imperial College, London, United Kingdom NICU, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Universita degli Studi di Milano, Milano, Italy
    Cortex 56:30-7. 2014
    ..We tested the hypothesis that these abnormalities develop during the late preterm period...
  23. doi Tractography of the corticospinal tracts in infants with focal perinatal injury: comparison with normal controls and to motor development
    Elise Roze
    Centre for the Developing Brain, Imperial College, Hammersmith Campus, London, UK
    Neuroradiology 54:507-16. 2012
    ....
  24. doi Outcomes after central grey matter injury in term perinatal hypoxic-ischaemic encephalopathy
    Miriam Martinez-Biarge
    Department of Paediatrics and Imaging Sciences, Imperial College London, UK
    Early Hum Dev 86:675-82. 2010
    ..We present a guide for predicting outcome at 2 years in different developmental domains based on the severity of injury seen in the basal ganglia and thalami (BGT) on neonatal MRI...
  25. doi A common neonatal image phenotype predicts adverse neurodevelopmental outcome in children born preterm
    J P Boardman
    Institute of Clinical Sciences, Imperial College London and MRC Clinical Sciences Centre, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
    Neuroimage 52:409-14. 2010
    ....
  26. pmc MRI Based Preterm White Matter Injury Classification: The Importance of Sequential Imaging in Determining Severity of Injury
    Miriam Martinez-Biarge
    Department of Paediatrics, Imperial College London, London, United Kingdom
    PLoS ONE 11:e0156245. 2016
    ..Our aim was to describe sequential MRI findings in preterm infants with non-hemorrhagic WMI and to develop an MRI classification system for preterm WMI based on these findings...
  27. ncbi The HIV care cascade among female sex workers in Zimbabwe: results of a population-based survey from the Sisters Antiretroviral therapy Programme for Prevention of HIV, an Integrated Response (SAPPH-IRe) Trial
    Frances M Cowan
    1Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK 2Centre for Sexual Health and HIV AIDS Research CeSHHAR Zimbabwe, Harare, Zimbabwe 3Centre for Evaluation, Department of Social and Environmental Health Research, Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK 4Women s Global Health Imperative, RTI International, San Francisco, California, United States of America 5United Nations Population Fund, Harare, Zimbabwe 6Gesellschaft für Internationale Zusammenarbeit, Harare, Zimbabwe 7Ministry of Health and Child Welfare, Harare, Zimbabwe 8Population Services International Global, Harare, Zimbabwe 9Department of Population Studies, Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    J Acquir Immune Defic Syndr . 2016
    ..Little is known about the HIV diagnosis and care cascade in most countries in southern Africa. We aimed to describe the HIV diagnosis and care cascade among FSW in Zimbabwe...
  28. pmc Poverty, food insufficiency and HIV infection and sexual behaviour among young rural Zimbabwean women
    Sophie J S Pascoe
    Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 10:e0115290. 2015
    ..Despite a recent decline, Zimbabwe still has the fifth highest adult HIV prevalence in the world at 14.7%; 56% of the population are currently living in extreme poverty...
  29. doi How you ask really matters: randomised comparison of four sexual behaviour questionnaire delivery modes in Zimbabwean youth
    Lisa F Langhaug
    University College London, London, UK
    Sex Transm Infect 87:165-73. 2011
    ..A sexual health survey among rural Zimbabwean youth was used to compare the validity and reliability of sexual behaviour measures between four questionnaire delivery modes...
  30. ncbi MR imaging quantification of cerebellar growth following hypoxic-ischemic injury to the neonatal brain
    Elisabeth Le Strange
    Robert Steiner Magnetic Resonance Unit, Imaging Sciences Department, Imperial College, Hammersmith Campus, Du Cane Road, London W12 0HS, England, UK
    AJNR Am J Neuroradiol 25:463-8. 2004
    ..We sought to determine whether perinatal hypoxic-ischemic injury leads to poor cerebellar growth and whether such impairment occurs asymmetrically in infants with predominantly unilateral brain injury...
  31. doi Neurological examination of preterm infants at term equivalent age
    Daniela Ricci
    Department of Paediatrics and Imaging Sciences, Hammersmith Campus, Imperial College, London, UK
    Early Hum Dev 84:751-61. 2008
    ..However, the cohort number was too small to draw any definitive conclusion about the distribution of findings...
  32. pmc Safety and Acceptability of the PrePex Device When Used in Routine Male Circumcision Service Delivery During Active Surveillance in Zimbabwe
    Webster Mavhu
    Centre for Sexual Health and HIV AIDS Research CeSHHAR, Harare, Zimbabwe Population Services International, Harare, Zimbabwe Ministry of Health and Child Care, Harare, Zimbabwe United States Agency for International Development, Harare, Zimbabwe University of Zimbabwe College of Health Sciences, Harare, Zimbabwe United States Agency for International Development, Washington, DC and University College London, London, United Kingdom
    J Acquir Immune Defic Syndr 72:S63-8. 2016
    ..Here, we present findings on safety and acceptability from active surveillance of the implementation of PrePex among 1000 males circumcised in Zimbabwe...
  33. pmc Difference in prevalence of common mental disorder as measured using four questionnaire delivery methods among young people in rural Zimbabwe
    Lisa F Langhaug
    Royal Free and University College Medical School, London, United Kingdom
    J Affect Disord 118:220-3. 2009
    ..We report here on differences in prevalence of reporting mental health between four questionnaire delivery modes (QDM)...
  34. pmc Perspectives of Parents and Health Care Workers on Early Infant Male Circumcision Conducted Using Devices: Qualitative Findings From Harare, Zimbabwe
    Webster Mavhu
    Centre for Sexual Health and HIV AIDS Research CeSHHAR, Harare, Zimbabwe University College London, London, United Kingdom
    Glob Health Sci Pract 4:S55-67. 2016
    ..Here, we present findings from a qualitative study in Zimbabwe that assessed parental and health care workers' perspectives of EIMC conducted using devices...
  35. pmc Statistical design and analysis plan for an impact evaluation of an HIV treatment and prevention intervention for female sex workers in Zimbabwe: a study protocol for a cluster randomised controlled trial
    James R Hargreaves
    Centre for Evaluation Department for Social and Environmental Health Research, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, 15 17 Tavistock Place, London, WC1H 9SH, UK
    Trials 17:6. 2016
    ....
  36. doi Evaluation of early childhood social-communication difficulties in children born preterm using the Quantitative Checklist for Autism in Toddlers
    Hilary S Wong
    Section of Neonatal Medicine, Department of Medicine, Chelsea and Westminster Hospital, Imperial College London, London, United Kingdom
    J Pediatr 164:26-33.e1. 2014
    ....
  37. ncbi T2 relaxation values in the developing preterm brain
    Serena J Counsell
    Robert Steiner MR Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Campus, Imperial College, DuCane Road, London, England
    AJNR Am J Neuroradiol 24:1654-60. 2003
    ..The aim of this study was to obtain T2 values in the preterm brain from 25 weeks' gestational age (GA) until term-equivalent age in infants who had normal neurodevelopmental findings at a minimum corrected age of 1 year...
  38. ncbi Using cerebral ultrasound effectively in the newborn infant
    Lara M Leijser
    Department of Paediatrics and Imaging Science Department, Imperial College, Hammersmith Hospital, Du Cane Road, London, UK
    Early Hum Dev 82:827-35. 2006
    ..Issues of concern regarding teaching, supervision and experience of the examiner are also addressed...
  39. ncbi Diffusion-weighted imaging of the brain in preterm infants with focal and diffuse white matter abnormality
    Serena J Counsell
    Robert Steiner Magnetic Resonance Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Campus, London, United Kingdom
    Pediatrics 112:1-7. 2003
    ....
  40. ncbi School based HIV prevention in Zimbabwe: feasibility and acceptability of evaluation trials using biological outcomes
    Frances M Cowan
    Department of Sexually Transmitted Diseases, Royal Free and University College Medical School, London, UK
    AIDS 16:1673-8. 2002
    ..To determine the feasibility and acceptability of conducting a community randomized trial (CRT) of an adolescent reproductive health intervention (ARHI) using biological measures of effectiveness...
  41. pmc Predicting motor outcome and death in term hypoxic-ischemic encephalopathy
    M Martinez-Biarge
    Department of Pediatrics, Hammersmith Hospital, London, UK
    Neurology 76:2055-61. 2011
    ....
  42. ncbi Maturation of cerebral electrical activity and development of cortical folding in young very preterm infants
    E Biagioni
    Department of Paediatrics, Imperial College Hammersmith Hospital, London, UK
    Clin Neurophysiol 118:53-9. 2007
    ..The aim of this study was to examine the relationship between cortical development and cerebral electrical activity at early gestational ages...
  43. ncbi Neurological and perceptual-motor outcome at 5 - 6 years of age in children with neonatal encephalopathy: relationship with neonatal brain MRI
    A Barnett
    Department of Paediatrics, Imperial College School of Medicine, Hammersmith Campus, London, United Kingdom
    Neuropediatrics 33:242-8. 2002
    ....
  44. pmc Neonatal cerebral infarction and visual function at school age
    E Mercuri
    Department of Paediatrics, Hammersmith Campus, Imperial College School of Medicine, London, UK
    Arch Dis Child Fetal Neonatal Ed 88:F487-91. 2003
    ..To assess various aspects of visual function at school age in children with neonatal cerebral infarction...
  45. ncbi Comparison of findings on cranial ultrasound and magnetic resonance imaging in preterm infants
    E F Maalouf
    Department of Paediatrics, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
    Pediatrics 107:719-27. 2001
    ..In addition, normal WM echogenicity on US is not a good predictor of normal WM signal intensity on MRI...
  46. ncbi Prothrombotic disorders and abnormal neurodevelopmental outcome in infants with neonatal cerebral infarction
    E Mercuri
    Departments of Paediatrics, Imperial College, Hammersmith Campus, London, United Kingdom
    Pediatrics 107:1400-4. 2001
    ....
  47. doi Probabilistic diffusion tractography of the optic radiations and visual function in preterm infants at term equivalent age
    Laura Bassi
    NICU, Institute of Pediatrics and Neonatology, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, University of Milan, Italy
    Brain 131:573-82. 2008
    ..Our results suggest that in preterm infants at term equivalent age visual function is directly related to the development of white matter in the optic radiations...
  48. ncbi Should cranial MRI screening of preterm infants become routine?
    Linda S de Vries
    Department of Neonatology, Wilhelmina Children s Hospital, Utrecht, The Netherlands
    Nat Clin Pract Neurol 3:532-3. 2007
  49. ncbi The value of autopsy in determining the cause of failure to respond to resuscitation at birth
    Waney Squier
    Department of Neuropathology, Radcliffe Infirmary, Oxford OX2 6HE, UK
    Semin Neonatol 9:331-45. 2004
    ..Metabolic disease, including peroxisomal disorders, non-ketotic hyperglycinaemia, lipid and glycogen storage disorders and mitochondrial diseases may cause profound hypotonia and respiratory failure at birth or shortly afterwards...