Affiliation: Imperial College
- Long-term reinfection of the human genome by endogenous retrovirusesRobert Belshaw
Department of Biological Sciences, Imperial College at Silwood Park, Ascot, Berks SL5 7PY, United Kingdom
Proc Natl Acad Sci U S A 101:4894-9. 2004..Analysis of the env gene of eight other HERV families indicated that reinfection is likely to be the most common mechanism by which endogenous retroviruses proliferate in their hosts...
- BlastAlign: a program that uses blast to align problematic nucleotide sequencesRobert Belshaw
Department of Biological Sciences, Imperial College Silwood Park Campus, Ascot, Berks SL5 7PY, UK
Bioinformatics 21:122-3. 2005..An additional Perl program BlastAlignP uses tblastn to align nucleotide sequences to a single amino acid sequence, thus allowing an open reading frame to be maintained in the resulting multiple alignment...
- Genomewide screening reveals high levels of insertional polymorphism in the human endogenous retrovirus family HERV-K(HML2): implications for present-day activityRobert Belshaw
Department of Biological Sciences, Imperial College, Ascot, Berks, United Kingdom
J Virol 79:12507-14. 2005..This view of the family from a population perspective rather than a genome perspective will inform the current debate about a possible role of HERV-K(HML2) in human disease...
- The cytogenetics of thelytoky in a predominantly asexual parasitoid wasp with covert sexRobert Belshaw
Department of Biological Sciences, Imperial College at Silwood Park, Ascot, Berks SL5 7PY, UK
Genome 46:170-3. 2003..No evidence of the bacterial symbiont Wolbachia was found, and the observed system was compared with that in parasitoid wasps where asexuality is the result of Wolbachia infection...
- Robustness of ancestral state estimates: evolution of life history strategy in ichneumonoid parasitoidsRobert Belshaw
Department of Biological Sciences, Imperial College at Silwood Park, Ascot, Berkshire SL5 7PY, UK
Syst Biol 51:450-77. 2002..We also discuss relationships within the superfamily and expand the Mesostoinae to include all the gall-associated braconids that form the sister group of the Aphidiinae...
- Conserved footprints of APOBEC3G on Hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequencesAndrew E Armitage
MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom
J Virol 82:8743-61. 2008....
- High copy number in human endogenous retrovirus families is associated with copying mechanisms in addition to reinfectionRobert Belshaw
Mol Biol Evol 22:814-7. 2005..We discuss why these other mechanisms are rare in most families and suggest why complementation in trans is significant only in the larger families...
- Phylogenetic evidence for deleterious mutation load in RNA viruses and its contribution to viral evolutionOliver G Pybus
Department of Zoology, University of Oxford, Oxford, United Kingdom
Mol Biol Evol 24:845-52. 2007..From this relationship, we propose an empirical threshold for the maximum viable deleterious mutation load in RNA viruses...
- Rate of recombinational deletion among human endogenous retrovirusesRobert Belshaw
Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
J Virol 81:9437-42. 2007....
- Pacing a small cage: mutation and RNA virusesRobert Belshaw
Department of Zoology, University of Oxford, Oxford, UK
Trends Ecol Evol 23:188-93. 2008..We explain the many terms used in investigating RNA viral evolution and highlight the specific experimental and comparative work that needs to be done...