Peter G Bain
Affiliation: Imperial College
- The management of tremorPeter G Bain
Department of Neurosciences, Imperial College, London, UK
J Neurol Neurosurg Psychiatry 72:I3-I9. 2002
- Parkinsonism & related disorders. TremorPeter G Bain
Movement Disorders and Neuromodulation Group, Division of Neurosciences and Mental Health, Imperial College London, UK
Parkinsonism Relat Disord 13:S369-74. 2007..Treatment of tremor depends on the severity and cause of tremor and includes medical therapy and stereotactic surgery including deep brain stimulation...
- Task-specific tremorPeter G Bain
Department of Medicine, Imperial College School of Medicine, Charing Cross Hospital Campus, London, UK
Handb Clin Neurol 100:711-8. 2011..Hyperactivity in the cerebellar hemispheres has been demonstrated with positron emission tomography in PWT. Other task-specific tremors have been described but have not been studied in detail...
- Intraoperative monitoring of motor symptoms using surface electromyography during stereotactic surgery for movement disordersXuguang Liu
The Movement Disorders and Neurostimulation Group, Department of Neurosciences, Charing Cross Hospital, Division of Neuroscience and Psychological Medicine, Imperial College London, London, UK
J Clin Neurophysiol 22:183-91. 2005....
- The sensory and motor representation of synchronized oscillations in the globus pallidus in patients with primary dystoniaXuguang Liu
Department of Physiology, Anatomy, and Genetics, University of Oxford, UK
Brain 131:1562-73. 2008..This study yields new insights into the pathophysiological mechanisms of primary dystonias and their treatment using pallidal deep brain stimulation...
- Quantifying drug-induced dyskinesias in the arms using digitised spiral-drawing tasksXuguang Liu
Movement Disorders and Neurostimulation Group, Charing Cross Hospital, Division of Neurosciences and Psychological Medicine, Imperial College, London W6 8RF, UK
J Neurosci Methods 144:47-52. 2005..We conclude that the drawing tasks may be used to provide an objective method of quantifying the severity of drug-induced dyskinesias in the arm in PD patients...
- Different mechanisms may generate sustained hypertonic and rhythmic bursting muscle activity in idiopathic dystoniaXuguang Liu
The Movement Disorders and Neurostimulation Unit, Charing Cross Hospital and Division of Neuroscience and Mental Health, Imperial College London, 11L15 East Block, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK
Exp Neurol 198:204-13. 2006..In contrast, the sustained hypertonic muscle activity may be represented by less synchronized activity in the pallidum. Thus, the pallidum may play different roles in generating different components of the dystonic symptom complex...
- Double-blind, single-dose, cross-over study of the effects of pramipexole, pergolide, and placebo on rest tremor and UPDRS part III in Parkinson's diseasePrithiva Navan
Division of Neurosciences and Psychological Medicine, Imperial College School of Medicine, Charing Cross Hospital Campus, London, United Kingdom
Mov Disord 18:176-80. 2003..006, Pr v Pl: P < 0.033). The two active drugs also had weaker beneficial effects on the UPDRS part III. Pergolide, however, was significantly more likely than pramipexole to cause nausea (P = 0.005) or vomiting (P = 0.014)...
- Orthostatic tremorLeah Jones
Imperial College London, London, UK
Pract Neurol 11:240-3. 2011..We discuss the clinical features, management and pathogenesis, and highlight the need for awareness of this condition because the diagnosis is often missed or delayed...
- The onset of voluntary reactive movement is temporally influenced by the central oscillation in action tremor caused by multiple sclerosisMichael F K Wong
The Movement Disorders and Neurostimulation Unit, Department of Clinical Neuroscience, Division of Neuroscience and Mental Health, Imperial College London and Department of Neuroscience, Charing Cross Hospital, London, UK
Neurosci Lett 445:122-5. 2008..In conclusion, in MS action tremor, the timing of the initiation of a rapid voluntary movement may be influenced by the pathological oscillator at a supra-spinal level...
- Effects on cognition of stereotactic lesional surgery for the treatment of tremor in multiple sclerosisMarjan Jahanshahi
Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, The National Hospital for Neurology and Neurosurgery, London, UK
Behav Neurol 20:1-9. 2008..To assess the effect of stereotactic lesional surgery for treatment of tremor in multiple sclerosis on cognition...
- Randomized, double-blind, 3-month parallel study of the effects of pramipexole, pergolide, and placebo on Parkinsonian tremorPrithiva Navan
Division of Neurosciences and Psychological Medicine, Imperial College London, Charing Cross Hospital Campus, London, United Kingdom
Mov Disord 18:1324-31. 2003..5 mg t.i.d.) have similar anti-PD tremor and UPDRS III actions that are significantly superior to placebo. Patients on pergolide were more likely to drop out because of adverse events than those on pramipexole...
- Post-deep brain stimulation--gradual non-stimulation dependent decrease in strength with attenuation of multiple sclerosis tremorJonathan A Hyam
Department of Neurosurgery, West London Neurosciences Centre Charing Cross Hospital, London, UK
J Neurol 254:854-60. 2007..There was also a significant correlation (0.699; p = 0.0359) between decreasing upper limb strength and decreasing intention tremor severity for the upper limbs of patients that had undergone contralateral DBS...
- 48, XXYY syndrome associated tremorHazel Lote
Department of Neurosciences, Imperial College London, Charing Cross Hospital Campus, London, UK
Pract Neurol 13:249-53. 2013..The tremor is typically reported as an intention tremor (in 71% of patients XXYY aged >20 years with 48), which becomes more common with age and worsens over time. ..
- Role of neuroimaging in the evaluation of tremorDavina J Hensman
Department of Neurosciences, Charing Cross Hospital, London, UK
Neuroimaging Clin N Am 20:77-86. 2010....
- Pregnancy in dystonic women with in situ deep brain stimulatorsAlessandro Paluzzi
Movement and Balance, Division of Neurosciences and Mental Health, Imperial College London, Charing Cross Hospital Campus, London, United Kingdom
Mov Disord 21:695-8. 2006..Based on this experience, we also provide an overview of some of the issues that might arise in pregnancy and during delivery in dystonic women with an in situ deep brain stimulator...
- The peri-electrode space is a significant element of the electrode-brain interface in deep brain stimulation: a computational studyNada Yousif
Department of Clinical Neuroscience, Division of Neuroscience and Mental Health, Faculty of Medicine, Imperial College London, UK
Brain Res Bull 74:361-8. 2007..This study leads to a fuller understanding of the EBI and its effects on the crossing electric currents, and will ultimately lead to optimisation of the therapeutic effects of DBS...
- Global attentional-executive sequelae following surgical lesions to globus pallidus internaRichard B Scott
Russell Cairns Unit, Radcliffe Infirmary, Oxford, UK
Brain 125:562-74. 2002..This finding is rare in its specificity and has implications for theoretical models of the functional architecture and pathophysiology of the globus pallidus, and the clinical practice of pallidotomy...
- Do on-off variations cause discrepancies in the historical items of the UPDRS?Camille B Carroll
Mov Disord 19:605. 2004
- The direction of oscillation in spiral drawings can be used to differentiate distal and proximal arm tremorShouyan Wang
University Laboratory of Physiology, Parks Road, Oxford OX1 3PT, UK
Neurosci Lett 384:188-92. 2005..We conclude that the spiral drawing task can be used as an objective and quantitative method for differentiating the involvement of the proximal and distal arm joints in complex arm tremors...
- Deep brain stimulation for movement disorders and painRichard G Bittar
Department of Neurosurgery, Radcliffe Infirmary, Oxford, UK
J Clin Neurosci 12:457-63. 2005..The indications for DBS in our service are outlined, the anatomical targets described, and the anaesthetic and surgical aspects detailed...
- Thalamotomy versus thalamic stimulation for multiple sclerosis tremorRichard G Bittar
Department of Neurosurgery, Radcliffe Infirmary, Oxford, UK
J Clin Neurosci 12:638-42. 2005....
- Physiological and harmonic components in neural and muscular coherence in Parkinsonian tremorShouyan Wang
Department of Physiology, Anatomy, and Genetics, University of Oxford, and Department of Neurosurgery, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK
Clin Neurophysiol 117:1487-98. 2006..To differentiate physiological from harmonic components in coherence analysis of the tremor-related neural and muscular signals by comparing power, cross-power and coherence spectra...
- Identifying cardiorespiratory neurocircuitry involved in central command during exercise in humansAlexander L Green
Department of Neurosurgery, Radcliffe Infirmary, Oxford OX2 6HE, UK
J Physiol 578:605-12. 2007....
- Use of surface electromyography to assess and select patients with idiopathic dystonia for bilateral pallidal stimulationShouyan Wang
University Laboratory of Physiology, University of Oxford, United Kingdom
J Neurosurg 105:21-5. 2006..The object of this study was to identify a preoperative physiological index by using surface electromyography (EMG) signals that would correlate with clinical outcome in dystonic patients following bilateral pallidal stimulation...
- A dominant bursting electromyograph pattern in dystonic conditions predicts an early response to pallidal stimulationJohn Yianni
Oxford Movement Disorder Group, Department of Neurological Surgery, Radcliffe Infirmary, Oxford, OX2 6HE, UK
J Clin Neurosci 13:738-46. 2006..Analysis of EMG activity may provide a sensitive means of identifying dystonic patients who are likely to be most responsive to functional neurosurgical intervention...
- Levodopa can worsen tremor associated with dystoniaDavina J Hensman
St George s, University of London, United Kingdom
Mov Disord 21:1778-80. 2006..A patient with tremor associated with spasmodic dysphonia developed a marked exacerbation of her upper limb tremor whilst on co-careldopa (Sinemet CR) that improved when the drug was withdrawn...
- Deep brain stimulation can regulate arterial blood pressure in awake humansAlexander L Green
Department of Neurosurgery, Radcliffe Infirmary, University of Oxford, Oxford, UK
Neuroreport 16:1741-5. 2005..05). These changes were accompanied by analogous changes in diastolic blood pressure, pulse pressure, maximum dP/dt but not in the time interval between each R wave on the electrocardiogram...
- Stereotactic and Functional Neurosurgery Resident Award: deep brain stimulation for generalized dystonia and spasmodic torticollis: rate and extent of postoperative improvementRichard G Bittar
Australasian Movement Disorder and Pain Surgery Clinic, Department of Surgery, Monash University, The Alfred Hospital, Melbourne
Clin Neurosurg 52:379-83. 2005
- Direct economic impact of Parkinson's disease: a research survey in the United KingdomLeslie Findley
Oldchurch Hospital, Romford, United Kingdom
Mov Disord 18:1139-45. 2003..In conclusion, PD imposes significant direct costs on public services and on individuals. These costs should be taken into account when allocating public funds...
- Deep brain stimulation for generalised dystonia and spasmodic torticollisRichard G Bittar
Department of Neurosurgery, Radcliffe Infirmary, Oxford, UK
J Clin Neurosci 12:12-6. 2005....
- Direction of tremor oscillation in spiral drawings reveals proximal versus distal muscle involvementXuguang Liu
Mov Disord 21:2032. 2006
- Functional Neurosurgery Resident Award: controlling the cardiovascular system with deep brain stimulationAlexander L Green
Department of Neurosurgery, Radcliffe Infirmary, Oxford, England
Clin Neurosurg 53:316-23. 2006