Sally Sharpe

Summary

Affiliation: Health Protection Agency
Country: UK

Publications

  1. ncbi request reprint Macaques infected long-term with attenuated simian immunodeficiency virus (SIVmac) remain resistant to wild-type challenge, despite declining cytotoxic T lymphocyte responses to an immunodominant epitope
    Sally A Sharpe
    Health Protection Agency, Porton Down, Salisbury SP4 0JG, UK
    J Gen Virol 85:2591-602. 2004
  2. pmc Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles
    Simon H Bridge
    Clinical Research Group, Liverpool School of Tropical Medicine, Liverpool, UK
    Virol J 8:429. 2011
  3. ncbi request reprint Mucosal immunization with PLGA-microencapsulated DNA primes a SIV-specific CTL response revealed by boosting with cognate recombinant modified vaccinia virus Ankara
    Sally Sharpe
    Health Protection Agency, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK
    Virology 313:13-21. 2003
  4. doi request reprint Determination of lesion volume by MRI and stereology in a macaque model of tuberculosis
    S A Sharpe
    Health Protection Agency, Centre for Emergency Preparedness and Response, Porton Down, Salisbury, SP4 0JG, UK
    Tuberculosis (Edinb) 89:405-16. 2009
  5. pmc Establishment of an aerosol challenge model of tuberculosis in rhesus macaques and an evaluation of endpoints for vaccine testing
    S A Sharpe
    Health Protection Agency, Centre for Emergency Preparedness and Response, Porton Down, Salisbury, United Kingdom
    Clin Vaccine Immunol 17:1170-82. 2010
  6. ncbi request reprint Single oral immunization with replication deficient recombinant adenovirus elicits long-lived transgene-specific cellular and humoral immune responses
    Sally Sharpe
    Centre for Applied Microbiology and Research, Salisbury SP4 0JG, United Kingdom
    Virology 293:210-6. 2002
  7. ncbi request reprint Infection of macaques with simian immunodeficiency virus induces a species-specific antibody response to major histocompatibility complex class I and class II molecules
    Natasha Polyanskaya
    Centre for Applied Microbiology and Research, Porton Down, Salisbury SP4 0JG, UK
    J Gen Virol 84:1671-6. 2003
  8. pmc Influenza A Virus Challenge Models in Cynomolgus Macaques Using the Authentic Inhaled Aerosol and Intra-Nasal Routes of Infection
    Anthony C Marriott
    National Infection Service, Public Health England, Porton Down, Wiltshire, United Kingdom
    PLoS ONE 11:e0157887. 2016
  9. ncbi request reprint Biodistribution and persistence of an MVA-vectored candidate HIV vaccine in SIV-infected rhesus macaques and SCID mice
    Tomas Hanke
    MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, The John Radcliffe, Oxford OX3 9DS, UK
    Vaccine 23:1507-14. 2005

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Macaques infected long-term with attenuated simian immunodeficiency virus (SIVmac) remain resistant to wild-type challenge, despite declining cytotoxic T lymphocyte responses to an immunodominant epitope
    Sally A Sharpe
    Health Protection Agency, Porton Down, Salisbury SP4 0JG, UK
    J Gen Virol 85:2591-602. 2004
    ....
  2. pmc Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles
    Simon H Bridge
    Clinical Research Group, Liverpool School of Tropical Medicine, Liverpool, UK
    Virol J 8:429. 2011
    ....
  3. ncbi request reprint Mucosal immunization with PLGA-microencapsulated DNA primes a SIV-specific CTL response revealed by boosting with cognate recombinant modified vaccinia virus Ankara
    Sally Sharpe
    Health Protection Agency, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK
    Virology 313:13-21. 2003
    ..Analysis of lymphoid tissues revealed a disseminated CTL response in peripheral and regional lymph nodes but not the spleen of both mucosally primed animals...
  4. doi request reprint Determination of lesion volume by MRI and stereology in a macaque model of tuberculosis
    S A Sharpe
    Health Protection Agency, Centre for Emergency Preparedness and Response, Porton Down, Salisbury, SP4 0JG, UK
    Tuberculosis (Edinb) 89:405-16. 2009
    ....
  5. pmc Establishment of an aerosol challenge model of tuberculosis in rhesus macaques and an evaluation of endpoints for vaccine testing
    S A Sharpe
    Health Protection Agency, Centre for Emergency Preparedness and Response, Porton Down, Salisbury, United Kingdom
    Clin Vaccine Immunol 17:1170-82. 2010
    ..Therefore, the currently proposed key markers were not shown to correlate with protection, and only imaging offered a potentially reliable correlate...
  6. ncbi request reprint Single oral immunization with replication deficient recombinant adenovirus elicits long-lived transgene-specific cellular and humoral immune responses
    Sally Sharpe
    Centre for Applied Microbiology and Research, Salisbury SP4 0JG, United Kingdom
    Virology 293:210-6. 2002
    ....
  7. ncbi request reprint Infection of macaques with simian immunodeficiency virus induces a species-specific antibody response to major histocompatibility complex class I and class II molecules
    Natasha Polyanskaya
    Centre for Applied Microbiology and Research, Porton Down, Salisbury SP4 0JG, UK
    J Gen Virol 84:1671-6. 2003
    ..In contrast to the species-specific response in infected animals, sera from animals vaccinated with inactivated human cell-grown SIV reacted to both human and rhesus MHC class I and class II molecules...
  8. pmc Influenza A Virus Challenge Models in Cynomolgus Macaques Using the Authentic Inhaled Aerosol and Intra-Nasal Routes of Infection
    Anthony C Marriott
    National Infection Service, Public Health England, Porton Down, Wiltshire, United Kingdom
    PLoS ONE 11:e0157887. 2016
    ..These more authentic infection models will be valuable in the determination of anti-influenza efficacy of novel entities against less severe (and thus more common) influenza infections...
  9. ncbi request reprint Biodistribution and persistence of an MVA-vectored candidate HIV vaccine in SIV-infected rhesus macaques and SCID mice
    Tomas Hanke
    MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, The John Radcliffe, Oxford OX3 9DS, UK
    Vaccine 23:1507-14. 2005
    ..Therefore, the MVA.HIVA vaccine is considered safe for application in phase I clinical trials in HIV-1-infected human subjects. These results also contribute to the confidence of using MVA as a smallpox vaccine...