A J Lawson

Summary

Affiliation: Health Protection Agency
Country: UK

Publications

  1. ncbi request reprint Real-time PCR detection and frequency of 16S rDNA mutations associated with resistance and reduced susceptibility to tetracycline in Helicobacter pylori from England and Wales
    Andrew J Lawson
    Campylobacter and Helicobacter Reference Unit, Laboratory of Enteric Pathogens, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5HT, UK
    J Antimicrob Chemother 56:282-6. 2005
  2. pmc Leukocyte-subset counts in idiopathic parkinsonism provide clues to a pathogenic pathway involving small intestinal bacterial overgrowth. A surveillance study
    R John Dobbs
    Pharmaceutical Science, King s College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH, UK
    Gut Pathog 4:12. 2012
  3. pmc Blood profile holds clues to role of infection in a premonitory state for idiopathic parkinsonism and of gastrointestinal infection in established disease
    Andre Charlett
    Therapeutics Research Group, Institute of Psychiatry at King s College London, London, UK
    Gut Pathog 1:20. 2009
  4. ncbi request reprint Molecular characterisation of an outbreak strain of multiresistant Salmonella enterica serovar Typhimurium DT104 in the UK
    A J Lawson
    Laboratory of Enteric Pathogens, Public Health Laboratory Service PHLS, Weybridge, New Haw, Surrey, UK
    Clin Microbiol Infect 10:143-7. 2004
  5. pmc Use of a LightCycler gyrA mutation assay for rapid identification of mutations conferring decreased susceptibility to ciprofloxacin in multiresistant Salmonella enterica serotype Typhimurium DT104 isolates
    R A Walker
    Laboratory of Enteric Pathogens, Central Public Health Laboratory, London NW9 5HT, United Kingdom
    J Clin Microbiol 39:1443-8. 2001
  6. pmc A national outbreak of multi-resistant Salmonella enterica serovar Typhimurium definitive phage type (DT) 104 associated with consumption of lettuce
    P W Horby
    Gastrointestinal Diseases Division, PHLS Communicable Disease Surveillance Centre CDSC, 61 Colindale Avenue, London, NW9 5EQ, UK
    Epidemiol Infect 130:169-78. 2003
  7. ncbi request reprint Subtyping intimin genes from enteropathogenic Escherichia coli associated with outbreaks and sporadic cases in the United Kingdom and Eire
    C Jenkins
    Laboratory of Enteric Pathogens, Central Public Health Laboratory, Specialist and Reference Microbiology Division, Health Protection Agency, 61 Colindale Avenue, NW9 5HT, London, UK
    Mol Cell Probes 17:149-56. 2003
  8. ncbi request reprint Heterogeneity in expression of lipopolysaccharide by strains of Salmonella enterica serotype Typhimurium definitive phage type 104 and related phage types
    A J Lawson
    Laboratory of Enteric Pathogens, Division of Gastrointestinal Infections, Central Public Health Laboratory, London, UK
    Lett Appl Microbiol 34:428-32. 2002
  9. pmc Detection of oxazolidinone-resistant Enterococcus faecalis and Enterococcus faecium strains by real-time PCR and PCR-restriction fragment length polymorphism analysis
    Neil Woodford
    Antibiotic Resistance Monitoring and Reference Laboratory Laboratory of Enteric Pathogens, Central Public Health Laboratory, London NW9 5HT, United Kingdom
    J Clin Microbiol 40:4298-300. 2002
  10. ncbi request reprint Application of 3'-mismatched reverse primer PCR compared with real-time PCR and PCR-RFLP for the rapid detection of 23S rDNA mutations associated with clarithromycin resistance in Helicobacter pylori
    Nicola C Elviss
    Helicobacter Reference Unit, Laboratory of Enteric Pathogens, Specialist and Reference Microbiology Division, Health Protection Agency, 61 Colindale Avenue, London NW9 5HT, UK
    Int J Antimicrob Agents 23:349-55. 2004

Collaborators

  • E J Threlfall
  • R H Davies
  • H R Smith
  • P Hunter
  • S J O'Brien
  • C Jenkins
  • H Chart
  • G Frankel
  • Robert J Owen
  • D M Livermore
  • Meeta Desai
  • Mark Kidd
  • R John Dobbs
  • Andre Charlett
  • Clive Weller
  • J Malcolm Plant
  • Sylvia M Dobbs
  • Mohammad A A Ibrahim
  • Nicola C Elviss
  • P W Horby
  • Elizabeth A Lindsay
  • Rachel A Walker
  • Neil Woodford
  • L R Ward
  • David Taylor
  • Ingvar Bjarnason
  • Owens Iguodala
  • R A Walker
  • Cori Smee
  • Dale W Peterson
  • James Bowthorpe
  • Alan Curry
  • Tracy Dew
  • Norman L Oxlade
  • Roy Sherwood
  • Ingvar T Bjarnason
  • M H Reacher
  • J I Hawker
  • R T Mitchell
  • G K Adak
  • C Lane
  • C Graham
  • Derek J Brown
  • Linda R Ward
  • Cressida Auckland
  • Hjordis Hardardottir
  • Wim J B Wannet
  • Luke Tysall
  • Ian S T Fisher
  • Mark W Stockdale
  • Paul D Crook
  • Fiona W Scott
  • Deborah Wilson
  • Helmut Tsch├Ąpe
  • M J Woodward
  • E Liebana
  • M Dassama
  • E A Lindsay
  • N Saunders

Detail Information

Publications14

  1. ncbi request reprint Real-time PCR detection and frequency of 16S rDNA mutations associated with resistance and reduced susceptibility to tetracycline in Helicobacter pylori from England and Wales
    Andrew J Lawson
    Campylobacter and Helicobacter Reference Unit, Laboratory of Enteric Pathogens, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5HT, UK
    J Antimicrob Chemother 56:282-6. 2005
    ....
  2. pmc Leukocyte-subset counts in idiopathic parkinsonism provide clues to a pathogenic pathway involving small intestinal bacterial overgrowth. A surveillance study
    R John Dobbs
    Pharmaceutical Science, King s College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH, UK
    Gut Pathog 4:12. 2012
    ..abstract:..
  3. pmc Blood profile holds clues to role of infection in a premonitory state for idiopathic parkinsonism and of gastrointestinal infection in established disease
    Andre Charlett
    Therapeutics Research Group, Institute of Psychiatry at King s College London, London, UK
    Gut Pathog 1:20. 2009
    ..Thus, two prognostic indicators in established IP fit with involvement of Helicobacter and SIBO...
  4. ncbi request reprint Molecular characterisation of an outbreak strain of multiresistant Salmonella enterica serovar Typhimurium DT104 in the UK
    A J Lawson
    Laboratory of Enteric Pathogens, Public Health Laboratory Service PHLS, Weybridge, New Haw, Surrey, UK
    Clin Microbiol Infect 10:143-7. 2004
    ..The study demonstrated the highly clonal nature of MR DT104 and the importance of a hierarchical approach to molecular subtyping for outbreak investigations...
  5. pmc Use of a LightCycler gyrA mutation assay for rapid identification of mutations conferring decreased susceptibility to ciprofloxacin in multiresistant Salmonella enterica serotype Typhimurium DT104 isolates
    R A Walker
    Laboratory of Enteric Pathogens, Central Public Health Laboratory, London NW9 5HT, United Kingdom
    J Clin Microbiol 39:1443-8. 2001
    ..This study confirmed that MR DT104 with decreased susceptibility to ciprofloxacin from humans and food animals in England and Wales may have arisen independently against a background of clonal spread of MR DT104...
  6. pmc A national outbreak of multi-resistant Salmonella enterica serovar Typhimurium definitive phage type (DT) 104 associated with consumption of lettuce
    P W Horby
    Gastrointestinal Diseases Division, PHLS Communicable Disease Surveillance Centre CDSC, 61 Colindale Avenue, London, NW9 5EQ, UK
    Epidemiol Infect 130:169-78. 2003
    ..This has implications for public health since food hazard warnings and product withdrawal are contingent on accurate identification of the suspect product...
  7. ncbi request reprint Subtyping intimin genes from enteropathogenic Escherichia coli associated with outbreaks and sporadic cases in the United Kingdom and Eire
    C Jenkins
    Laboratory of Enteric Pathogens, Central Public Health Laboratory, Specialist and Reference Microbiology Division, Health Protection Agency, 61 Colindale Avenue, NW9 5HT, London, UK
    Mol Cell Probes 17:149-56. 2003
    ..The beta-intimin gene was the most frequently detected sub-type in both the outbreak and sporadic strains...
  8. ncbi request reprint Heterogeneity in expression of lipopolysaccharide by strains of Salmonella enterica serotype Typhimurium definitive phage type 104 and related phage types
    A J Lawson
    Laboratory of Enteric Pathogens, Division of Gastrointestinal Infections, Central Public Health Laboratory, London, UK
    Lett Appl Microbiol 34:428-32. 2002
    ..To investigate lipopolysaccharide (LPS) expression in Salmonella enterica serotype Typhimurium definitive phage type 104 (Salmonella Typhimurium DT104) and related phage types...
  9. pmc Detection of oxazolidinone-resistant Enterococcus faecalis and Enterococcus faecium strains by real-time PCR and PCR-restriction fragment length polymorphism analysis
    Neil Woodford
    Antibiotic Resistance Monitoring and Reference Laboratory Laboratory of Enteric Pathogens, Central Public Health Laboratory, London NW9 5HT, United Kingdom
    J Clin Microbiol 40:4298-300. 2002
    ..Both assays detected isolates heterozygous at this position. Recognition of isolates with what is presently the most frequent oxazolidinone resistance mutation may aid surveillance and individual case management...
  10. ncbi request reprint Application of 3'-mismatched reverse primer PCR compared with real-time PCR and PCR-RFLP for the rapid detection of 23S rDNA mutations associated with clarithromycin resistance in Helicobacter pylori
    Nicola C Elviss
    Helicobacter Reference Unit, Laboratory of Enteric Pathogens, Specialist and Reference Microbiology Division, Health Protection Agency, 61 Colindale Avenue, London NW9 5HT, UK
    Int J Antimicrob Agents 23:349-55. 2004
    ..The novel 3M-PCR assay format was the most sensitive, detecting all alleles at > or =0.02 ng/microl in DNA mixtures, and thus provides more precise information to guide clinical management of patients at risk of treatment failure...
  11. pmc Fluorescent amplified fragment length polymorphism subtyping of multiresistant Salmonella enterica serovar Typhimurium DT104
    Andrew J Lawson
    Laboratory of Enteric Pathogens, Specialist and Reference Microbiology Division, Health Protection Agency, London, United Kingdom
    J Clin Microbiol 42:4843-5. 2004
    ..A single FAFLP profile was shared by 93% of outbreak-associated isolates and 82% of sporadic isolates. This study demonstrates the value of FAFLP as a high-resolution tool for epidemiological investigation of Salmonella...
  12. pmc Multiply resistant (MR) Salmonella enterica serotype Typhimurium DT 12 and DT 120: a case of MR DT 104 in disguise?
    Andrew J Lawson
    Central Public Health Laboratory, London, UK
    Emerg Infect Dis 8:434-6. 2002
    ..Multiresistant DT 12 and DT 120 appear to have arisen due to changes in phage susceptibility of DT 104 rather than horizontal transfer of resistance genes...
  13. ncbi request reprint Investigation of the biological relevance of Helicobacter pylori cagE locus diversity, presence of CagA tyrosine phosphorylation motifs and vacuolating cytotoxin genotype on IL-8 induction in gastric epithelial cells
    Robert J Owen
    Laboratory of Enteric Pathogens, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT, UK
    FEMS Immunol Med Microbiol 36:135-40. 2003
    ....
  14. pmc Role of electronic data exchange in an international outbreak caused by Salmonella enterica serotype Typhimurium DT204b
    Elizabeth A Lindsay
    Public Health Laboratory Service Laboratory of Enteric Pathogens, London, United Kingdom
    Emerg Infect Dis 8:732-4. 2002
    ..This investigation highlights the importance of standardized protocols for molecular typing in international outbreaks of foodborne disease...