Affiliation: Guy's and St Thomas' NHS Foundation Trust
- Long-term adherence to a 5 day antibiotic course guideline for treatment of intensive care unit (ICU)-associated Gram-negative infectionsJonathan D Edgeworth
Centre for Clinical Infection and Diagnostic Research CIDR, Department of Infectious Diseases, Kings College London and Guy s and St Thomas NHS Foundation Trust, St Thomas Hospital, Westminster Bridge Road, London SE1 7EH, UK
J Antimicrob Chemother 69:1688-94. 2014..To determine long-term adherence to a 5 day antibiotic course guideline for treating intensive care unit (ICU)-acquired Gram-negative bacteria (GNB) infections...
- Adjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia (ARREST): study protocol for a randomised controlled trialGuy Thwaites
Department of Infectious Diseases Centre for Clinical Infection and Diagnostics Research, Kings College London Guy s and St, Thomas Hospitals NHS Foundation Trust, London, England, United Kingdom
Trials 13:241. 2012..Our aim is to determine whether adjunctive rifampicin reduces all-cause mortality within 14 days and bacteriological failure or death within 12 weeks from randomisation...
- Selection for qacA carriage in CC22, but not CC30, methicillin-resistant Staphylococcus aureus bloodstream infection isolates during a successful institutional infection control programmeJonathan A Otter
Centre for Clinical Infection and Diagnostics Research CIDR, Department of Infectious Diseases, King s College London and Guy s and St Thomas NHS Foundation Trust, London, UK
J Antimicrob Chemother 68:992-9. 2013..We evaluated the carriage of chlorhexidine resistance genes and chlorhexidine susceptibility in MRSA before and after introduction of an institutional MRSA control programme incorporating chlorhexidine-based decolonization in 2004...
- An outbreak in an intensive care unit of a strain of methicillin-resistant Staphylococcus aureus sequence type 239 associated with an increased rate of vascular access device-related bacteremiaJonathan D Edgeworth
Department of Infection, Guy s and St Thomas National Health Service Foundation Trust, St Thomas Hospitals, London, SE1 7EH, UK
Clin Infect Dis 44:493-501. 2007..We report an epidemiological and bacterial genomic analysis of a 2-year outbreak in an intensive care unit of a variant of MRSA sequence type 239 (hereafter designated TW)...
- Intravascular catheter infectionsJ Edgeworth
Guy s and St Thomas Hospital, London SE1 7EH, UK
J Hosp Infect 73:323-30. 2009....
- Has decolonization played a central role in the decline in UK methicillin-resistant Staphylococcus aureus transmission? A focus on evidence from intensive careJonathan D Edgeworth
Directorate of Infection, Guy s and St Thomas NHS Foundation Trust, St Thomas Hospital, London, UK
J Antimicrob Chemother 66:ii41-7. 2011..The dissemination of chlorhexidine-resistant MRSA would have implications for the decolonization of individual patients and for preventing transmission...
- Clinical application of real-time PCR to screening critically ill and emergency-care surgical patients for methicillin-resistant Staphylococcus aureus: a quantitative analytical studyM Trent Herdman
Directorate of Infection, St Thomas Hospital, Guy s and St Thomas NHS Foundation Trust, London SE1 7EH, United Kingdom
J Clin Microbiol 47:4102-8. 2009....
- Efficacy and limitation of a chlorhexidine-based decolonization strategy in preventing transmission of methicillin-resistant Staphylococcus aureus in an intensive care unitRahul Batra
Directorate of Infection, Guy s and St Thomas National Health Service Foundation Trust, London, UK
Clin Infect Dis 50:210-7. 2010..We report on the effect of an antiseptic protocol on acquisition of both endemic MRSA and an outbreak strain of MRSA sequence type 239 (designated TW)...
- Rapid determination of hospital-acquired meticillin-resistant Staphylococcus aureus lineagesJoshua D Cockfield
Centre for Infection, Department of Cellular and Molecular Medicine, St George s, University of London, Cranmer Terrace, London SW17 0RE, UK
J Med Microbiol 56:614-9. 2007..Simple and accurate typing methods will also support large scale epidemiological studies, and could lead to greater understanding of the carriage, spread and virulence of different MRSA lineages...