John D Perry

Summary

Affiliation: Freeman Hospital
Country: UK

Publications

  1. ncbi Synthesis and evaluation of novel chromogenic aminopeptidase substrates for microorganism detection and identification
    Arthur L James
    School of Applied Sciences, Northumbria University, Newcastle upon Tyne, NE1 8ST, UK
    Bioorg Med Chem Lett 17:1418-21. 2007
  2. ncbi Evaluation of novel chromogenic substrates for the detection of bacterial beta-glucosidase
    J D Perry
    Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, UK
    J Appl Microbiol 102:410-5. 2007
  3. pmc Evaluation of S. aureus ID, a new chromogenic agar medium for detection of Staphylococcus aureus
    John D Perry
    Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    J Clin Microbiol 41:5695-8. 2003
  4. doi A novel chromogenic medium for isolation of Pseudomonas aeruginosa from the sputa of cystic fibrosis patients
    Larissa Laine
    Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, UK
    J Cyst Fibros 8:143-9. 2009
  5. pmc Use of faropenem as an indicator of carbapenemase activity in the Enterobacteriaceae
    Kathryn M Day
    Microbiology Department, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    J Clin Microbiol 51:1881-6. 2013
  6. doi Routine Use of Probiotics in Preterm Infants: Longitudinal Impact on the Microbiome and Metabolome
    Bashir Abdulkadir
    Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK
    Neonatology 109:239-47. 2016
  7. doi Determining the influence of environmental and patient specific factors on the polymicrobial communities of the cystic fibrosis airway
    Andrew Nelson
    Faculty of Health and Life Sciences, Northumbria University, Ellison Building, Newcastle upon Tyne, NE1 8ST, UK
    Antonie Van Leeuwenhoek 103:755-62. 2013
  8. doi In vitro activity of S-(3,4-dichlorobenzyl)isothiourea hydrochloride and novel structurally related compounds against multidrug-resistant bacteria, including Pseudomonas aeruginosa and Burkholderia cepacia complex
    Audrey Nicholson
    Microbiology Department, Freeman Hospital, Newcastle upon Tyne, UK
    Int J Antimicrob Agents 39:27-32. 2012
  9. doi Prevalence and molecular characterization of Enterobacteriaceae producing NDM-1 carbapenemase at a military hospital in Pakistan and evaluation of two chromogenic media
    Kathryn M Day
    Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, UK
    Diagn Microbiol Infect Dis 75:187-91. 2013
  10. pmc Development and evaluation of a chromogenic agar medium for methicillin-resistant Staphylococcus aureus
    John D Perry
    Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, United Kingdom
    J Clin Microbiol 42:4519-23. 2004

Collaborators

Detail Information

Publications30

  1. ncbi Synthesis and evaluation of novel chromogenic aminopeptidase substrates for microorganism detection and identification
    Arthur L James
    School of Applied Sciences, Northumbria University, Newcastle upon Tyne, NE1 8ST, UK
    Bioorg Med Chem Lett 17:1418-21. 2007
    ....
  2. ncbi Evaluation of novel chromogenic substrates for the detection of bacterial beta-glucosidase
    J D Perry
    Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, UK
    J Appl Microbiol 102:410-5. 2007
    ..To evaluate three previously unreported substrates for the detection of beta-glucosidase activity in clinically relevant bacteria and to compare their performance with a range of known substrates in an agar medium...
  3. pmc Evaluation of S. aureus ID, a new chromogenic agar medium for detection of Staphylococcus aureus
    John D Perry
    Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    J Clin Microbiol 41:5695-8. 2003
    ..aureus compared with 94.4% of mauve colonies on CHROMagar Staph. aureus. We conclude that S. aureus ID is a highly sensitive and specific medium for the isolation and identification of S. aureus from wound swabs...
  4. doi A novel chromogenic medium for isolation of Pseudomonas aeruginosa from the sputa of cystic fibrosis patients
    Larissa Laine
    Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, UK
    J Cyst Fibros 8:143-9. 2009
    ..A novel chromogenic medium for isolation and identification of Pseudomonas aeruginosa from sputa of cystic fibrosis (CF) patients was evaluated and compared with standard laboratory methods...
  5. pmc Use of faropenem as an indicator of carbapenemase activity in the Enterobacteriaceae
    Kathryn M Day
    Microbiology Department, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    J Clin Microbiol 51:1881-6. 2013
    ..Disc susceptibility testing using faropenem (10 μg) is a simple, convenient, and highly predictive screening test for carbapenemase-producing Enterobacteriaceae...
  6. doi Routine Use of Probiotics in Preterm Infants: Longitudinal Impact on the Microbiome and Metabolome
    Bashir Abdulkadir
    Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK
    Neonatology 109:239-47. 2016
    ..Probiotics are live microbial supplements that colonize the gut and potentially exert health benefit to the host...
  7. doi Determining the influence of environmental and patient specific factors on the polymicrobial communities of the cystic fibrosis airway
    Andrew Nelson
    Faculty of Health and Life Sciences, Northumbria University, Ellison Building, Newcastle upon Tyne, NE1 8ST, UK
    Antonie Van Leeuwenhoek 103:755-62. 2013
    ..This is the first paper to identify a reduced bacterial diversity in female patients with CF and to implicate more severe CFTR genotypes with increased risk of infection with multiple fungal species...
  8. doi In vitro activity of S-(3,4-dichlorobenzyl)isothiourea hydrochloride and novel structurally related compounds against multidrug-resistant bacteria, including Pseudomonas aeruginosa and Burkholderia cepacia complex
    Audrey Nicholson
    Microbiology Department, Freeman Hospital, Newcastle upon Tyne, UK
    Int J Antimicrob Agents 39:27-32. 2012
    ..This work establishes the activity of isothiourea derivatives against a broad range of clinically important MDR bacteria...
  9. doi Prevalence and molecular characterization of Enterobacteriaceae producing NDM-1 carbapenemase at a military hospital in Pakistan and evaluation of two chromogenic media
    Kathryn M Day
    Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, UK
    Diagn Microbiol Infect Dis 75:187-91. 2013
    ..NDM-1 carbapenemase was most commonly found amongst commensal types of Escherichia coli, especially phylogenetic group B1...
  10. pmc Development and evaluation of a chromogenic agar medium for methicillin-resistant Staphylococcus aureus
    John D Perry
    Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, United Kingdom
    J Clin Microbiol 42:4519-23. 2004
    ..5, 99.3, 97.9, and 92.8%, respectively, after 22 to 24 h of incubation. We conclude that MRSA ID is a sensitive and specific medium for the isolation and identification of MRSA...
  11. pmc Temporal bacterial and metabolic development of the preterm gut reveals specific signatures in health and disease
    Christopher J Stewart
    Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, NE1 8ST, United Kingdom
    Microbiome 4:67. 2016
    ..We performed detailed temporal bacterial (n = 641) and metabolomic (n = 75) profiling of the gut microbiome throughout the disease...
  12. pmc Preterm gut microbiota and metabolome following discharge from intensive care
    Christopher J Stewart
    Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, United Kingdom
    Sci Rep 5:17141. 2015
    ..Further work is needed to establish the direct effect of weaning as a key event in promoting future gut health. ..
  13. pmc Evaluation of a chromogenic culture medium for isolation of Clostridium difficile within 24 hours
    John D Perry
    Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    J Clin Microbiol 48:3852-8. 2010
    ..difficile generated higher colony counts on IDCd irrespective of alcohol pretreatment or duration of incubation. We conclude that IDCd is an effective medium for isolation of C. difficile from stool samples within 24 h...
  14. pmc Development of the preterm gut microbiome in twins at risk of necrotising enterocolitis and sepsis
    Christopher J Stewart
    Faculty of Health and Life Sciences, University of Northumbria, Newcastle upon Tyne, United Kingdom
    PLoS ONE 8:e73465. 2013
    ..Environmental factors including antibiotic exposure and feeding are additional significant determinants of community structure, regardless of host genetics. ..
  15. pmc Comparison of four chromogenic culture media for carbapenemase-producing Enterobacteriaceae
    Kathryn M Wilkinson
    Microbiology Department, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    J Clin Microbiol 50:3102-4. 2012
    ..The corresponding sensitivities of Trypticase soy broth plus ertapenem or meropenem were 78% and 47%, respectively...
  16. pmc Evaluation of Various Culture Media for Detection of Rapidly Growing Mycobacteria from Patients with Cystic Fibrosis
    Clair L Preece
    Microbiology Department, Freeman Hospital, Newcastle upon Tyne, United Kingdom Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, United Kingdom
    J Clin Microbiol 54:1797-803. 2016
    ..Furthermore, the convenience of using RGM medium enables routine screening for rapidly growing NTM in all submitted sputum samples from patients with CF. ..
  17. doi Comparison of BD GeneOhm real-time polymerase chain reaction with chromogenic and conventional culture methods for detection of group B Streptococcus in clinical samples
    Dawn Smith
    Microbiology Department, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK
    Diagn Microbiol Infect Dis 61:369-72. 2008
    ..5% versus 57% respectively, P < 0.02). After selective enrichment, 92.8% of GBS were isolated on chromID Strepto B compared with 89.2% isolated on sheep blood agar...
  18. doi Recovery of antimicrobial-resistant Pseudomonas aeruginosa from sputa of cystic fibrosis patients by culture on selective media
    John D Perry
    Department of Microbiology, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK
    J Antimicrob Chemother 61:1057-61. 2008
    ..To assess the utility of direct plating of whole sputa onto selective media as a means of identifying antimicrobial resistance in strains of Pseudomonas aeruginosa from the sputa of patients with cystic fibrosis (CF)...
  19. doi A novel culture medium for isolation of rapidly-growing mycobacteria from the sputum of patients with cystic fibrosis
    Clair L Preece
    Microbiology Department, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK
    J Cyst Fibros 15:186-91. 2016
    ..A novel selective culture medium (RGM medium) was evaluated for the isolation of rapidly-growing NTM from the sputum of children and adults with CF...
  20. doi Nocardia kroppenstedtii sp. nov., an actinomycete isolated from a lung transplant patient with a pulmonary infection
    Amanda L Jones
    School of Biology, University Newcastle, Newcastle upon Tyne, NE1 7RU, UK
    Int J Syst Evol Microbiol 64:751-4. 2014
    ..It is concluded that strain N1286(T) represents a novel species of the genus Nocardia for which the name Nocardia kroppenstedtii sp. nov. is proposed. The type strain is N1286(T) ( = DSM 45810(T) = NCTC 13617(T))...
  21. ncbi Polymicrobial challenges to Koch's postulates: ecological lessons from the bacterial vaginosis and cystic fibrosis microbiomes
    Andrew Nelson
    School of Applied Sciences, University of Northumbria, Newcastle upon Tyne, UK
    Innate Immun 18:774-83. 2012
    ..Ecological theory offers a theoretical framework around which testable hypotheses can be developed to clarify the polymicrobial nature and dynamics of such infections in the face of environmental change and therapeutic interventions...
  22. doi Prevalence of faecal carriage of Enterobacteriaceae with NDM-1 carbapenemase at military hospitals in Pakistan, and evaluation of two chromogenic media
    John D Perry
    Microbiology Department, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK
    J Antimicrob Chemother 66:2288-94. 2011
    ....
  23. pmc Determination of Carboxypeptidase Activity in Clinical Pathogens by Gas Chromatography-Mass Spectrometry
    Fraser Lough
    Department of Applied Sciences, Northumbria University, Newcastle upon Tyne, UK
    Anal Lett 49:1272-1277. 2016
    ..However, the method is well-suited for identifying carboxypeptidase activities that have not been previously described or to corroborate a carboxypeptidase assay with the ninhydrin reagent...
  24. doi Non cystic fibrosis bronchiectasis: A longitudinal retrospective observational cohort study of Pseudomonas persistence and resistance
    Melissa J McDonnell
    Institute of Cellular Medicine Newcastle University and Adult Bronchiectasis Service, Department of Respiratory Medicine, The Freeman Hospital, Newcastle upon Tyne, UK
    Respir Med 109:716-26. 2015
    ..These data are important in determining risk stratification and follow up...
  25. doi Guidelines for the diagnosis and antibiotic treatment of endocarditis in adults: a report of the Working Party of the British Society for Antimicrobial Chemotherapy
    F Kate Gould
    Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, UK
    J Antimicrob Chemother 67:269-89. 2012
    ..The guidelines have also been extended by the inclusion of sections on clinical diagnosis, echocardiography and surgery...
  26. doi Primary bronchial epithelial cell culture from explanted cystic fibrosis lungs
    Malcolm Brodlie
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    Exp Lung Res 36:101-10. 2010
    ..This provides an important cellular model to elucidate the pathogenic mechanisms in cystic fibrosis lung disease and to investigate potential therapeutic targets...
  27. doi The effect of ex vivo lung perfusion on microbial load in human donor lungs
    Anders Andreasson
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne Cardiopulmonary Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne
    J Heart Lung Transplant 33:910-6. 2014
    ..In this study, we investigated the effect of EVLP on the microbial load of human donor lungs...
  28. doi Identification of volatile organic compounds produced by bacteria using HS-SPME-GC-MS
    Emma Tait
    1Department of Applied Sciences, Northumbria University, Ellison Building, Newcastle upon Tyne, NE1 8ST, UK
    J Chromatogr Sci 52:363-73. 2014
    ..The whole process is limited by the need to grow the bacteria in broth (18 h) before extraction and analysis (63 min). ..
  29. doi Dietzia papillomatosis sp. nov., a novel actinomycete isolated from the skin of an immunocompetent patient with confluent and reticulated papillomatosis
    Amanda L Jones
    School of Biology, King George VIth Building, University of Newcastle, Newcastle upon Tyne NE1 7RU, UK
    Int J Syst Evol Microbiol 58:68-72. 2008
    ..It is apparent from genotypic and phenotypic data that the organism represents a novel species in the genus Dietzia. The name proposed for this taxon is Dietzia papillomatosis; the type strain is N 1280(T) (=DSM 44961(T)=NCIMB 14145(T))...
  30. doi Synthesis and testing of chromogenic phenoxazinone substrates for beta-alanyl aminopeptidase
    Andrey V Zaytsev
    Pharmacy, Chemistry and Biomedical Sciences, University of Sunderland, Sunderland, SR1 3SD, U K
    Org Biomol Chem 6:682-92. 2008
    ....