Ibtisam E Tothill
Affiliation: Cranfield University
- Rational design of a polymer specific for microcystin-LR using a computational approachIva Chianella
Institute of BioScience and Technology, Cranfield University, Silsoe, Bedfordshire, UK
Anal Chem 74:1288-93. 2002..It is anticipated that the polymer designed could be used in assays, sensors, and solid-phase extraction...
- The use of differential scanning fluorimetry in the rational design of plastic antibodies for protein targetsJon Ashley
Cranfield University, College Road, Cranfield, Bedfordshire MK43 0AL, England, UK
Analyst 141:6463-6470. 2016..The technique is simple, rapid and can be carried out on most quantitative polymerase chain reaction (qPCR) thermal cyclers which have the required filters for SYPRO..
- Biosensors for cancer markers diagnosisIbtisam E Tothill
Cranfield Health, Cranfield University, Cranfield, Bedfordshire, MK 43 0AL England, UK
Semin Cell Dev Biol 20:55-62. 2009..This review provides an overview of the biosensor technology available today, areas which are currently being developed and researched for cancer markers diagnosis-and a consideration of future prospects for the technology...
- Real-time and sensitive detection of Salmonella Typhimurium using an automated quartz crystal microbalance (QCM) instrument with nanoparticles amplificationFaridah Salam
Cranfield Health, Cranfield University, Cranfield, Bedfordshire, MK43 0AL England, United Kingdom
Talanta 115:761-7. 2013....
- Development of urease and glutamic dehydrogenase amperometric assay for heavy metals screening in polluted samplesBelen Bello Rodriguez
Cranfield Biotechnology Centre, Institute of Bioscience, Cranfield University, Silsoe, Bedforshire MK45 4DT, UK
Biosens Bioelectron 19:1157-67. 2004..This approach provides to be a simple and rapid (15 min, including enzyme inhibition time) method for metal ions detection...
- Comparative investigations for adenovirus recognition and quantification: Plastic or natural antibodies?Zeynep Altintas
Cranfield University, Cranfield, Bedfordshire, MK43 0AL England, UK Electronic address
Biosens Bioelectron 74:996-1004. 2015..This work confirmed the suitability of the MIPs SPR sensor for the detection of viruses...
- Surface plasmon resonance based immunosensor for the detection of the cancer biomarker carcinoembryonic antigenZeynep Altintas
Cranfield University, Cranfield Health, Cranfield, Bedfordshire MK43 0AL, UK
Talanta 86:377-83. 2011..The developed SPR immunosensor using the sandwich assay format showed high sensitivity and reproducibility for CEA detection which makes it a promising procedure for cancer biomarker analysis...
- Cancer biomarker detection in serum samples using surface plasmon resonance and quartz crystal microbalance sensors with nanoparticle signal amplificationYildiz Uludag
Cranfield Health, Cranfield University, Cranfield, Bedfordshire, UK
Anal Chem 84:5898-904. 2012..This demonstrates the high potential of the developed sensor devices as platforms for clinical prostate cancer diagnosis and prognosis...
- Urease-glutamic dehydrogenase biosensor for screening heavy metals in water and soil samplesBelen Bello Rodriguez
Cranfield Biotechnology Centre, Cranfield University, Silsoe, MK45 4DT, Beds, UK
Anal Bioanal Chem 380:284-92. 2004..Nevertheless, the use of the amperometric assay (with free urease) proved more feasible for the screening of trace amounts of metals in polluted samples...
- Development of cysteine-modified screen-printed electrode for the chronopotentiometric stripping analysis of cadmium(II) in wastewater and soil extractsMohd F Md Noh
School of Industrial and Manufacturing Science, Cranfield University, Building 61, Cranfield, Bedfordshire, MK43 0AL, UK
Anal Bioanal Chem 382:1175-86. 2005..These results demonstrate the feasibility of using this type of sensor for cadmium analysis...
- Biosensors for waterborne viruses: Detection and removalZeynep Altintas
Biomedical Engineering, Cranfield University, Bedfordshire, MK43 0AL, England, UK Electronic address
Biochimie 115:144-54. 2015..This review reports on the latest technologies used for waterborne virus removal and detection with focus on rapid detection using biosensors. ..
- Detection of the inflammation biomarker C-reactive protein in serum samples: towards an optimal biosensor formulaWellington M Fakanya
Centre of Biomedical Engineering, Cranfield University, Cranfield, Bedfordshire, MK43 0AL, UK E Mail Atlas, Derby Court, Epsom Square, White Horse Business Park, Trowbridge, BA14 0XG, UK
Biosensors (Basel) 4:340-57. 2014....
- Ultrasensitive detection of endotoxins using computationally designed nanoMIPsZeynep Altintas
Cranfield University, Cranfield, Bedfordshire MK43 0AL, England, UK Technical University of Berlin, Straße des 17 Juni 124, Berlin 10623, Germany Electronic address
Anal Chim Acta 935:239-48. 2016....
- Detection of Waterborne Viruses Using High Affinity Molecularly Imprinted PolymersZeynep Altintas
Biomedical Engineering, Cranfield University, Bedfordshire MK43 0AL, United Kingdom
Anal Chem 87:6801-7. 2015....
- SPR detection of cardiac troponin T for acute myocardial infarctionMaria Pawula
Cranfield University, Cranfield, Bedfordshire, MK43 0AL England, UK
Talanta 146:823-30. 2016..This method can also be used for the rapid detection of biomarkers in central nervous system diseases...
- Sensitive detection of Campylobacter jejuni using nanoparticles enhanced QCM sensorNoor Azlina Masdor
Cranfield University, Cranfield, Bedfordshire, MK43 0AL England, UK Biotechnology Research Centre, Malaysian Agricultural Research and Development Institute MARDI, P O Box 12301, Kuala Lumpur, Malaysia
Biosens Bioelectron 78:328-36. 2016..This work demonstrates the potential of this technology for the development of a rapid and sensitive detection method for C. jejuni. ..
- Cardiovascular disease detection using bio-sensing techniquesZeynep Altintas
Advanced Diagnostics and Sensors Group, Cranfield University, Cranfield, Bedfordshire MK43 0AL, UK
Talanta 128:177-86. 2014..This review summarised the classification of CVD, the biomarkers used for its diagnosis, biosensors and their application including the latest developments in the field of heart-disease detection. ..
- Computational design of peptide ligands for ochratoxin AMeike Heurich
Cranfield Health, Cranfield University, Cranfield, Bedfordshire MK43 0AL, England, UK
Toxins (Basel) 5:1202-18. 2013..This work illustrates the potential of using computational modelling to design a peptide sequence that exhibits in vitro binding affinity for a small molecular weight toxin...
- Development of an electrochemical immunosensor for fumonisins detection in foodsMohamad Kamal Abdul Kadir
Cranfield University, Cranfield Health, Cranfield, Bedfordshire, MK43 0AL, UK
Toxins (Basel) 2:382-98. 2010..onboard Ag-AgCl pseudo-reference electrode. The immunosensor exhibited detection limit of 5 µg·L(-1) fumonisins with a dynamic range from 1 µg·L(-1)-1000 µg·L(-1). The sensor also performed well in extracted corn samples...
- Development of a sensitive detection method of cancer biomarkers in human serum (75%) using a quartz crystal microbalance sensor and nanoparticles amplification systemYildiz Uludag
Cranfield University, Cranfield Health, Cranfield, Bedfordshire MK43 0AL, England, UK
Talanta 82:277-82. 2010..With the achieved detection limit in serum samples, the developed QCM assay shows a promising technology for cancer biomarker analysis in patient samples...
- Electrochemical immunochip sensor for aflatoxin M1 detectionCharlie O Parker
Cranfield Health, Cranfield University, Cranfield, Bedfordshire, MK43 0AL, UK
Anal Chem 81:5291-8. 2009..The milk interference with the sensor surface was also found to be minimal. These devices show high potential for development of a range of new applications which have previously only been detected using elaborate instrumentation...
- Development of disposable bulk-modified screen-printed electrode based on bismuth oxide for stripping chronopotentiometric analysis of lead (II) and cadmium (II) in soil and water samplesRashid O Kadara
Cranfield Health, Cranfield University, Silsoe, Bedfordshire MK45 4DT, UK
Anal Chim Acta 623:76-81. 2008..The analytical utility of the modified electrode was illustrated by the stripping chronopotentiometric determinations of lead (II) in soil extracts and wastewater samples...
- Combination of amplification and post-amplification strategies to improve optical DNA sensingElsa Giakoumaki
Cranfield Biotechnology Centre, Cranfield University, Silsoe, Bedfordshire MK45 4DT, UK
Biosens Bioelectron 19:337-44. 2003..The effective combination of the two strategies allowed a rapid and specific hybridisation reaction. The developed method was successfully applied in the detection of genetically modified organisms...
- Development and characterisation of disposable gold electrodes, and their use for lead(II) analysisMohd F Md Noh
Cranfield Health, Cranfield University, Silsoe, MK45 4DT, UK
Anal Bioanal Chem 386:2095-106. 2006..For comparison purposes a mercury-film electrode and ICP-MS were used for validation...
- Benzene analysis in workplace air using an FIA-based bacterial biosensorYvonne H Lanyon
Cranfield Biotechnology Centre, Cranfield University, Silsoe, Bedfordshire MK45 4DT, UK
Biosens Bioelectron 20:2089-96. 2005....
- Detection of Salmonella typhimurium using an electrochemical immunosensorFaridah Salam
Cranfield Health, Cranfield University, Cranfield, Bedfordshire, MK43 0AL, United Kingdom
Biosens Bioelectron 24:2630-6. 2009..The sensor format shows a promising technology for simple and sensitive detection system for Salmonella contamination. Rapid detection of Salmonella is a key to the prevention and identification of problems related to health and safety...
- Development of an electrochemical immunosensor for aflatoxin M1 in milk with focus on matrix interferenceCharlie O Parker
Cranfield Health, Cranfield University, Cranfield, Bedfordshire MK43 0AL, UK
Biosens Bioelectron 24:2452-7. 2009..The immunsensor was comparable, in term of sensitivity, but vastly superior in term of portability and cost therefore a key instrument for the detection of aflatoxin M(1) at the source of the contamination...
- L-malic acid biosensor for field-based evaluation of apple, potato and tomato horticultural produceMobeen Arif
Cranfield Biotechnology Centre, Cranfield University, Silsoe, Bedfordshire, UK
Analyst 127:104-8. 2002..7% of a standard commercially available photometric test kit. The sensor approach is cheap, simple to perform and rapid (6 min), requiring only buffer-electrolyte and a small sample volume...