N Andrews

Summary

Affiliation: Central Public Health Laboratory
Country: UK

Publications

  1. ncbi Does oral polio vaccine cause intussusception in infants? Evidence from a sequence of three self-controlled cases series studies in the United Kingdom
    N Andrews
    Public Health Laboratory Service Statistics Unit, London, UK
    Eur J Epidemiol 17:701-6. 2001
  2. ncbi Statistical assessment of the association between vaccination and rare adverse events post-licensure
    N J Andrews
    Public Health Laboratory Service, Statistics Unit, 61 Colindale Avenue, NW9 5EQ, London, UK
    Vaccine 20:S49-53; discussion S45-8. 2001
  3. doi Comparative hepatitis A seroepidemiology in 10 European countries
    S Kurkela
    Health Protection Agency, Health Protection Services, Colindale, London, UK
    Epidemiol Infect 140:2172-81. 2012
  4. ncbi Risks of convulsion and aseptic meningitis following measles-mumps-rubella vaccination in the United Kingdom
    E Miller
    Immunisation Department, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London, UK
    Am J Epidemiol 165:704-9. 2007
  5. doi Investigating tuberculosis trends in England
    J P Crofts
    Respiratory Diseases Department, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    Public Health 122:1302-10. 2008
  6. doi A comparison of hepatitis B seroepidemiology in ten European countries
    A Nardone
    Centre for Infections, Health Protection Agency, London, UK
    Epidemiol Infect 137:961-9. 2009
  7. ncbi The comparative sero-epidemiology of varicella zoster virus in 11 countries in the European region
    A Nardone
    Health Protection Agency, Centre for Infections, London, UK
    Vaccine 25:7866-72. 2007
  8. ncbi Sero-epidemiology of Bordetella pertussis in England and Wales
    A Nardone
    Immunisation Division, Communicable Disease Surveillance Centre, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    Vaccine 22:1314-9. 2004
  9. ncbi Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom: mid-season analysis 2010/11
    R Pebody
    Health Protection Agency Health Protection Services Colindale, London, UK
    Euro Surveill 16:. 2011
  10. ncbi Review of the effect of measles vaccination on the epidemiology of SSPE
    H Campbell
    Immunisation Department, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5EQ, UK
    Int J Epidemiol 36:1334-48. 2007

Detail Information

Publications43

  1. ncbi Does oral polio vaccine cause intussusception in infants? Evidence from a sequence of three self-controlled cases series studies in the United Kingdom
    N Andrews
    Public Health Laboratory Service Statistics Unit, London, UK
    Eur J Epidemiol 17:701-6. 2001
    ..The discovery of an increased risk of an intestinal obstruction known as intussusception following live rotavirus vaccination raised questions about the possibility of a link between live OPV and intussusception...
  2. ncbi Statistical assessment of the association between vaccination and rare adverse events post-licensure
    N J Andrews
    Public Health Laboratory Service, Statistics Unit, 61 Colindale Avenue, NW9 5EQ, London, UK
    Vaccine 20:S49-53; discussion S45-8. 2001
    ..In this paper, the three methods are reviewed and compared and examples are given of recent applications. The effects of potential sources of bias are demonstrated using a data set on MMR vaccine and convulsions...
  3. doi Comparative hepatitis A seroepidemiology in 10 European countries
    S Kurkela
    Health Protection Agency, Health Protection Services, Colindale, London, UK
    Epidemiol Infect 140:2172-81. 2012
    ..Romania, however, appeared as an area with intermediate transmission. Vaccination of risk groups in countries with high susceptibility of young and middle-aged adults needs to be continued...
  4. ncbi Risks of convulsion and aseptic meningitis following measles-mumps-rubella vaccination in the United Kingdom
    E Miller
    Immunisation Department, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London, UK
    Am J Epidemiol 165:704-9. 2007
    ..48, 95% confidence interval: 0.88, 2.50) as occurred with Urabe-containing vaccines. This study demonstrates the power of active postmarketing surveillance to identify or exclude events too rare to be detected in prelicensure trials...
  5. doi Investigating tuberculosis trends in England
    J P Crofts
    Respiratory Diseases Department, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    Public Health 122:1302-10. 2008
    ..To investigate the factors associated with the increasing incidence of tuberculosis in England...
  6. doi A comparison of hepatitis B seroepidemiology in ten European countries
    A Nardone
    Centre for Infections, Health Protection Agency, London, UK
    Epidemiol Infect 137:961-9. 2009
    ..Regular serological surveys to ascertain HBV status within a population, such as reported here, provide important data to assess the need for and to evaluate universal HBV vaccination programmes...
  7. ncbi The comparative sero-epidemiology of varicella zoster virus in 11 countries in the European region
    A Nardone
    Health Protection Agency, Centre for Infections, London, UK
    Vaccine 25:7866-72. 2007
    ..There are substantial differences in VZV sero-epidemiology within the European region, which will need to be taken into account in designing national policies regarding VZV vaccination...
  8. ncbi Sero-epidemiology of Bordetella pertussis in England and Wales
    A Nardone
    Immunisation Division, Communicable Disease Surveillance Centre, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    Vaccine 22:1314-9. 2004
    ..There is an important incidence of infection in the population, which is greater amongst children than adults, but there is only limited evidence of a correlation with epidemic cycles...
  9. ncbi Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom: mid-season analysis 2010/11
    R Pebody
    Health Protection Agency Health Protection Services Colindale, London, UK
    Euro Surveill 16:. 2011
    ....
  10. ncbi Review of the effect of measles vaccination on the epidemiology of SSPE
    H Campbell
    Immunisation Department, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5EQ, UK
    Int J Epidemiol 36:1334-48. 2007
    ..We conducted a comprehensive review of the impact of measles immunization on the epidemiology of SSPE and examined epidemiological evidence on whether there was any vaccine-associated risk...
  11. pmc No evidence of an association between MMR vaccine and gait disturbance
    E Miller
    Immunisation Division, Public Health Laboratory Service, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    Arch Dis Child 90:292-6. 2005
    ..MMR vaccine has been reported to cause gait disturbance, and this possible association has been claimed to support the MMR-causes-autism theory...
  12. ncbi Immunogenicity and reactogenicity of acellular diphtheria/tetanus/pertussis vaccines given as a pre-school booster: effect of simultaneous administration of MMR
    E Miller
    Immunisation Division, PHLS Communicable Disease Surveillance Centre, 61 Colindale Avenue, London NW9 5EQ, UK
    Vaccine 19:3904-11. 2001
    ....
  13. doi Estimating seroprevalence of vaccine-preventable infections: is it worth standardizing the serological outcomes to adjust for different assays and laboratories?
    G Kafatos
    Public Health England, London, UK
    Epidemiol Infect 143:2269-78. 2015
    ....
  14. pmc Investigating urban-rural disparities in tuberculosis treatment outcome in England and Wales
    I Abubakar
    Respiratory Diseases Department, Centre for Infections, Health Protection Agency, London, UK
    Epidemiol Infect 136:122-7. 2008
    ..02, 95% CI 0.83-1.26, P=0.82) after adjusting for the confounding effects of ethnic group and age. In England and Wales residence in a rural location is not an independent determinant of TB treatment outcome failure...
  15. ncbi The European Sero-Epidemiology Network 2: standardization of assay results for hepatitis B virus
    G Kafatos
    Health Protection Agency Centre for Infections, London, UK
    J Viral Hepat 14:260-8. 2007
    ..Standardization is a very important tool that allows for international serological comparisons to assess the current vaccination policies and the progress of HBV control in Europe...
  16. pmc The epidemiology of subacute sclerosing panencephalitis in England and Wales 1990-2002
    C Miller
    Immunisation Department, Communicable Disease Surveillance Centre, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    Arch Dis Child 89:1145-8. 2004
    ..To assess the impact of measles/mumps/rubella (MMR) vaccine on the epidemiology of subacute sclerosing panencephalitis (SSPE) in England and Wales...
  17. ncbi Host and environmental factors associated with Hib in England, 1998-2002
    J McVernon
    Immunisation Department, Health Protection Agency Centre for Infections, London, UK
    Arch Dis Child 93:670-5. 2008
    ..Declining effectiveness of the UK's Hib vaccine programme was observed between 1998 and 2002...
  18. pmc Recall bias, MMR, and autism
    N Andrews
    Statistics Unit, Public Health Laboratory Service, 61 Colindale Avenue, London NW9 5EQ, UK
    Arch Dis Child 87:493-4. 2002
    ..This is consistent with the recall bias expected under such circumstances...
  19. ncbi Measles immunity testing: comparison of two measles IgG ELISAs with plaque reduction neutralisation assay
    B J Cohen
    Virus Reference Department, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London NW9 5HT, UK
    J Virol Methods 131:209-12. 2006
    ..The specificity of both ELISAs was 100%. Measles IgG ELISAs perform adequately for immunity testing, correctly identifying seronegative individuals for vaccination...
  20. pmc Sero-epidemiology of mumps in western Europe
    A Nardone
    PHLS Communicable Disease Surveillance Centre, 61 Colindale Avenue, London, NW9 SEQ, UK
    Epidemiol Infect 131:691-701. 2003
    ..Sero-surveillance of mumps is an important component of disease control and its usefulness will be enhanced by the development of an international mumps standard...
  21. doi Mortality caused by influenza and respiratory syncytial virus by age group in England and Wales 1999-2010
    P Hardelid
    Statistics Unit, Health Protection Agency Centre for Infections, London, UK
    Influenza Other Respir Viruses 7:35-45. 2013
    ..The mortality burden caused by influenza cannot be quantified directly from death certificates because of under-recording; therefore, the estimated number of influenza deaths has to be obtained through statistical modelling...
  22. doi Use of antibiotics and risk factors for carriage of Streptococcus pneumoniae: a longitudinal household study in the United Kingdom
    R G Pebody
    Centre for Infections, Health Protection Agency, London, UK
    Epidemiol Infect 137:555-61. 2009
    ..52, 95% CI 1.41-4.52). Taking antibiotics significantly reduces the risk of carriage the following month in a setting with a low prevalence of pneumococcal antimicrobial resistance...
  23. pmc Hepatitis A virus infection in people of South Asian origin in England and Wales: analysis of laboratory reports between 1992 and 2004
    U Gungabissoon
    Health Protection Agency Centre for Infections, London, UK
    Epidemiol Infect 135:549-54. 2007
    ..Targeted information campaigns may be indicated in regions of the United Kingdom for people in South Asian minority ethnic groups...
  24. ncbi Institutional risk factors for outbreaks of nosocomial gastroenteritis: survival analysis of a cohort of hospital units in South-west England, 2002-2003
    B A Lopman
    Gastrointestinal Diseases Department, Communicable Disease Surveillance Centre, Health Protection Agency, London, UK
    J Hosp Infect 60:135-43. 2005
    ..80-0.99]. Larger care units and those with higher throughput have increased rates of gastroenteritis outbreaks. These results should guide infection control policy and support the design of hospitals with smaller care units...
  25. pmc Vaccine coverage in England: the impact of health service reorganisation
    J Granerod
    Immunisation Department, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5EQ, UK
    Arch Dis Child 91:805-7. 2006
    ..To evaluate the impact of reorganisation of the health service and a change in the definition used to collect immunisation coverage statistics on vaccine coverage data in England...
  26. pmc Effectiveness of different policies in preventing meningococcal disease clusters following a single case in day-care and pre-school settings in Europe
    D Boccia
    European Programme for Intervention Epidemiology Training, Health Protection Agency Centre for Infections, London, UK
    Epidemiol Infect 134:872-7. 2006
    ..8, 95% CI 0.7-22.0), although the difference was not statistically significant (P=0.22). The costs of this approach and the low risk of clustering need to be taken into account when deciding national policy...
  27. ncbi Immunogenicity of one, two or three doses of a meningococcal C conjugate vaccine conjugated to tetanus toxoid, given as a three-dose primary vaccination course in UK infants at 2, 3 and 4 months of age with acellular pertussis-containing DTP/Hib vaccine
    J Southern
    Immunisation Department, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    Vaccine 24:215-9. 2006
    ..These results suggest that a reduced number of doses of MCC-TT would be adequate in infancy if given concomitantly with an acellular pertussis-containing vaccine...
  28. pmc Bacterial infections, immune overload, and MMR vaccine. Measles, mumps, and rubella
    E Miller
    Immunisation Division, Communicable Disease Surveillance Centre, Public Health Laboratory Service, 61 Colindale Avenue, London NW9 5EQ, UK
    Arch Dis Child 88:222-3. 2003
    ..These results provide no support for the concept of "immunological overload" induced by multiple antigen vaccinations, nor calls for single antigen vaccines...
  29. pmc Deaths from pertussis are underestimated in England
    N S Crowcroft
    Demography and Health, Office for National Statistics, 1 Drummmond Gate, London SW1V 2QQ, UK
    Arch Dis Child 86:336-8. 2002
    ..To improve estimates of deaths from pertussis in England and to identify reasons for under ascertainment...
  30. ncbi Illness absenteeism rates in primary and secondary schools in 2013-2014 in England: was there any impact of vaccinating children of primary-school age against influenza?
    H K Green
    Centre for Infectious Disease Surveillance and Control, Public Health England, London, UK
    Epidemiol Infect . 2016
    ..These insights can be used in conjunction with routine healthcare surveillance data to evaluate the full benefits of such a programme...
  31. doi Age-specific vaccine effectiveness of seasonal 2010/2011 and pandemic influenza A(H1N1) 2009 vaccines in preventing influenza in the United Kingdom
    R G Pebody
    Health Protection Agency Health Protection Services Colindale, London, UK
    Epidemiol Infect 141:620-30. 2013
    ..PIV administered during the previous season provided residual protection after 1 year, particularly in the <5 years age group...
  32. doi Screening for Corynebacterium diphtheriae and Corynebacterium ulcerans in patients with upper respiratory tract infections 2007-2008: a multicentre European study
    K S Wagner
    Immunisation, Hepatitis and Blood Safety Department, Health Protection Agency Centre for Infection, London, UK
    Clin Microbiol Infect 17:519-25. 2011
    ..ulcerans in highly-vaccinated populations highlights the need to maintain microbiological surveillance, laboratory expertise and an awareness of these organisms amongst public health specialists, microbiologists and clinicians...
  33. doi Impact of reduced numbers of isolates phage-typed on the detection of Salmonella outbreaks
    G Kafatos
    Health Protection Agency, Centre for Infections, London, UK
    Epidemiol Infect 137:821-7. 2009
    ....
  34. ncbi Development and evaluation of an antibody capture ELISA for detection of IgG to Epstein-Barr virus in oral fluid samples
    C Sheppard
    Enteric, Respiratory and Neurological Virus Laboratory, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT, UK
    J Virol Methods 93:157-66. 2001
    ..4--73.9% in measles, mumps, and rubella patients and 22.2% in atopic dermatitis study participants. A robust, reliable and reproducible EBV GACELISA has been developed which will be a useful tool for epidemiological investigations...
  35. doi Impact of influenza vaccination on respiratory illness rates in children attending private boarding schools in England, 2013-2014: a cohort study
    N Brousseau
    Immunisation, Hepatitis and Blood Safety Department, Public Health England, London, UK
    Epidemiol Infect 143:3405-15. 2015
    ..Additional research is needed to investigate the impact of influenza vaccination in non-boarding secondary-school settings. ..
  36. ncbi Risk of vaccine failure after Haemophilus influenzae type b (Hib) combination vaccines with acellular pertussis
    J McVernon
    Immunisation Division, Health Protection Agency Communicable Disease Surveillance Centre, Colindale, London, UK
    Lancet 361:1521-3. 2003
    ..More cases than controls received all three doses of their infant primary course as DTaP-Hib, compared with two or three doses of another Hib vaccine (conditional odds ratio 6.77 [95% CI 3.26-14.07])...
  37. pmc The seroepidemiology of herpes simplex virus type 1 and 2 in Europe
    R G Pebody
    Immunisation Department, Communicable Disease Surveillance Centre, London, UK
    Sex Transm Infect 80:185-91. 2004
    ..To describe the seroepidemiology of herpes simplex virus (HSV) types 1 and 2 in the general populations of eight European countries to better understand recent reported changes in disease epidemiology...
  38. pmc Improved hepatitis C treatment response in younger patients: findings from the UK HCV National Register cohort study
    H E Harris
    Immunisation, Hepatitis and Blood Safety Department, Health Protection Services Colindale, Health Protection Agency, 61 Colindale Ave, London, UK
    Epidemiol Infect 140:1830-7. 2012
    ..During the first two decades of chronic HCV infection, treatment at a younger age was found to be more influential in achieving a sustained viral response than treating earlier in the course of infection...
  39. doi Excess mortality monitoring in England and Wales during the influenza A(H1N1) 2009 pandemic
    P Hardelid
    Statistics Unit, Health Protection Agency Centre for Infections, London, UK
    Epidemiol Infect 139:1431-9. 2011
    ..This new system has utility for rapidly estimating excess mortality for other acute public health events such as extreme heat or cold weather...
  40. ncbi The prevalence of hepatitis C in England and Wales
    M A Balogun
    Immunisation Division, PHLS Communicable Disease Surveillance Centre, 61 Colindale Avenue, London, NW9 5EQ, UK
    J Infect 45:219-26. 2002
    ..To estimate the background population prevalence of hepatitis C in England and Wales, observe the prevalence over time and assess the extent of infection outside of known risk groups...
  41. ncbi Risk of relapse after meningococcal C conjugate vaccine in nephrotic syndrome
    A S Abeyagunawardena
    Nephrourology Unit, Institute of Child Health, London, UK
    Lancet 362:449-50. 2003
    ..009). The relapse rate of nephrotic syndrome increased significantly after administration of MCCV. Whether to vaccinate such children needs to be carefully considered...
  42. ncbi Exposure to varicella boosts immunity to herpes-zoster: implications for mass vaccination against chickenpox
    M Brisson
    Immunisation Division, PHLS Communicable Disease Surveillance Centre, London, UK
    Vaccine 20:2500-7. 2002
    ..Mass varicella vaccination is expected to cause a major epidemic of herpes-zoster, affecting more than 50% of those aged 10-44 years at the introduction of vaccination...
  43. pmc Modelling the hepatitis B vaccination programme in prisons
    A J Sutton
    Health Protection Agency, Modelling and Economics Unit, Colindale, London, UK
    Epidemiol Infect 134:231-42. 2006
    ..The HBV vaccination programme in prisons is an effective way of vaccinating this hard-to-reach population although vaccination coverage on prison reception must be increased to achieve this...