W S Atkin
Affiliation: Cancer Research UK
- A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21Ian Tomlinson
Molecular and Population Genetics Laboratory, Cancer Research UK, London WC2A 3PX, UK
Nat Genet 39:984-8. 2007..21, 95% c.i.: 1.10-1.34; P = 6.89 x 10(-5)). These data show that common, low-penetrance susceptibility alleles predispose to colorectal neoplasia...
- Options for screening for colorectal cancerW Atkin
Colorectal Cancer Unit, Cancer Research UK, St Mark s Hospital, Northwick Park, Harrow, UK
Scand J Gastroenterol Suppl . 2003....
- Wide variation in adenoma detection rates at screening flexible sigmoidoscopyWendy Atkin
Colorectal Unit, Cancer Research UK, St Mark s Hospital, Northwick Park, Harrow, Middlesex HA1 3UJ, England, UK
Gastroenterology 126:1247-56. 2004....
- Surveillance guidelines after removal of colorectal adenomatous polypsW S Atkin
Cancer Research UK, Colorectal Cancer Unit, St Mark s Hospital, Harrow, Middlesex HA1 3UJ, UK
Gut 51:V6-9. 2002
- Protagonist: population based endoscopic screening for colorectal cancerW S Atkin
Cancer Research UK Colorectal Cancer Unit, St Mark s Hospital, Northwick Park, Middlesex, UK
Gut 52:321-2. 2003
- Single blind, randomised trial of efficacy and acceptability of oral picolax versus self administered phosphate enema in bowel preparation for flexible sigmoidoscopy screeningW S Atkin
Imperial Cancer Research Fund Colorectal Cancer Unit, St Mark s Hospital, Northwick Park, Harrow HA1 3UJ
BMJ 320:1504-8; discussion 1509. 2000..To compare the acceptability and efficacy of two methods of self administered bowel preparation for flexible sigmoidoscopy screening: a single phosphate enema and a single sachet of Picolax...
- Flexible sigmoidoscopy as a mass screening toolW S Atkin
ICRF Colorectal Cancer Unit, St Mark s Hospital, Northwick Park, Harrow, Middlesex, UK
Eur J Gastroenterol Hepatol 10:219-23. 1998..Several randomized trials, including a large British study, are currently evaluating these aspects...
- Design of a multicentre randomised trial to evaluate flexible sigmoidoscopy in colorectal cancer screeningW S Atkin
Imperial Cancer Research Fund Colorectal Cancer Unit, St Mark s Hospital, Harrow, Middlesex, UK
J Med Screen 8:137-44. 2001..The first analysis of the effect on colorectal cancer incidence and mortality rates and suitability for a national screening programme can be expected in 2004...
- Increasing attendance at colorectal cancer screening: testing the efficacy of a mailed, psychoeducational intervention in a community sample of older adultsJane Wardle
Cancer Research UK, Health Behavior Unit, Department of Epidemiology and Public Health, University College London, 2 16 Torrington Place, London WC1E 6BT, England, UK
Health Psychol 22:99-105. 2003..6% higher level of attendance. These results indicate that psychoeducational interventions can provide an effective means of modifying attitudes and increasing rates of screening attendance...
- Attitudes to colorectal cancer screening among ethnic minority groups in the UKKathryn A Robb
Cancer Research UK Health Behaviour Research Centre, Department of Epidemiology and Public Health, UCL, Gower Street, London, WC1E 6BT, UK
BMC Public Health 8:34. 2008..To ensure equality of access, it is important to understand attitudes towards screening in all ethnic groups so that barriers to screening acceptance can be addressed...
- Uptake of population-based flexible sigmoidoscopy screening for colorectal cancer: a nurse-led feasibility studyHannah Brotherstone
Cancer Research UK Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
J Med Screen 14:76-80. 2007..To assess uptake of once-only flexible sigmoidoscopy (FS) in a community sample to determine whether FS would be viable as a method of population-based screening for colorectal cancer...
- The impact of illustrations on public understanding of the aim of cancer screeningHannah Brotherstone
Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
Patient Educ Couns 63:328-35. 2006..To study the effectiveness of visual illustrations in improving people's understanding of the preventive aim of flexible sigmoidoscopy (FS) screening...
- Polyp measurement and size categorisation by CT colonography: effect of observer experience in a multi-centre settingDavid Burling
Intestinal Imaging Centre, St Marks Hospital, London, UK
Eur Radiol 16:1737-44. 2006..e. large polyps misclassified as medium). Caution should be exercised for polyps whose colonographic diameter is below but close to the 1-cm boundary threshold in order to avoid potential miscategorisation of advanced adenomas...
- History of negative colorectal endoscopy and risk of rectosigmoid neoplasms at screening flexible sigmoidoscopyLuigina Bonelli
Secondary Prevention and Screening, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Int J Colorectal Dis 21:105-13. 2006....
- Socioeconomic differences in cancer screening participation: comparing cognitive and psychosocial explanationsJane Wardle
Department of Epidemiology and Public Health, Cancer Research UK Health Behaviour Unit, University College London, 2 16 Torrington Place, London WC1E 6BT, UK
Soc Sci Med 59:249-61. 2004..Only the inclusion of the cognitive variables significantly reduced the variation associated with SES, providing better support for the cognitive than the psychosocial model...
- Psychological impact of colorectal cancer screeningJane Wardle
Cancer Research UK, Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, 2 16 Torrington Place, London WC1E 6BT, England
Health Psychol 22:54-9. 2003..The longitudinal data suggested that screening might produce transient positive effects...
- The effects of colorectal cancer screening on health attitudes and practicesAnne Miles
Cancer Research UK Health Behavior Unit, Department of Epidemiology and Public Health, University College London, London WC1 6BT, United Kingdom
Cancer Epidemiol Biomarkers Prev 12:651-5. 2003
- Receiving a screen-detected diagnosis of cancer: the experience of participants in the UK flexible sigmoidoscopy trialAnne Miles
Cancer Research UK Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, UK
Psychooncology 12:784-802. 2003..However, any interventions aimed at reducing the distress of a screen-detected cancer would need to consider the overall benefit to screening attenders, most of whom will have benign polyps detected...
- Detection of malondialdehyde DNA adducts in human colorectal mucosa: relationship with diet and the presence of adenomasChiara Leuratti
Medical Research Council Toxicology Unit, University of Leicester, Leicester LE1 9HN, United Kingdom
Cancer Epidemiol Biomarkers Prev 11:267-73. 2002..061). When levels of adducts were compared in individuals with and without adenomas, there was a trend for higher levels in individuals presenting with adenomas especially in the highest category of M(1)-dG adducts (P < 0.005)...
- Standardized colonoscopy reporting and data system: report of the Quality Assurance Task Group of the National Colorectal Cancer RoundtableDavid Lieberman
Division of Gastroenterology, Oregon Health and Science University, Portland VA Medical Center, Portland, Oregon 97239, USA
Gastrointest Endosc 65:757-66. 2007..The Quality Assurance Task Group of the National Colorectal Cancer Roundtable developed a reporting and data system for colonoscopy based on continuous quality improvement indicators...
- Cardiovascular effects at multi-detector row CT colonography compared with those at conventional endoscopy of the colonStuart A Taylor
Department of Intestinal Imaging, St Mark s Hospital, Level 4V, Watford Road, Northwick Park, London HA1 3UJ, England, United Kingdom
Radiology 229:782-90. 2003..To compare the cardiovascular effects of computed tomographic (CT) colonography and conventional endoscopy in a group of patients undergoing both procedures...
- Polyp measurement using CT colonography: agreement with colonoscopy and effect of viewing conditions on interobserver and intraobserver agreementDavid Burling
Intestinal Imaging Centre, St Mark s Hospital, Harrow, Middlesex, England HA1 3UJ
AJR Am J Roentgenol 186:1597-604. 2006..This article presents inter- and intraobserver agreement for estimates of polyp diameter using CT colonography, including the effects of different visualization displays and prior experience...
- CT colonography interpretation times: effect of reader experience, fatigue, and scan findings in a multi-centre settingDavid Burling
Intestinal Imaging Centre, St Marks Hospital, London, UK
Eur Radiol 16:1745-9. 2006..Technicians who report more slowly are more accurate. All groups reported faster as the study period progressed...
- CT colonography in the detection of colorectal polyps and cancer: systematic review, meta-analysis, and proposed minimum data set for study level reportingSteve Halligan
Department of Specialist Radiology, University College Hospital, Euston Rd, London, NW1 2BU, England
Radiology 237:893-904. 2005..To assess the methodologic quality of available data in published reports of computed tomographic (CT) colonography by performing systematic review and meta-analysis...
- CT colonography: effect of experience and training on reader performanceStuart A Taylor
Department of Intestinal Imaging, St Mark s Hospital, Watford Road, Northwick Park, London HA1 3UJ, UK
Eur Radiol 14:1025-33. 2004..There is considerable variation in the ability to report CT colonography. Prior experience in gastrointestinal radiology is a distinct advantage. Competence cannot be assumed even after directed training via a database of 50 cases...
- Unbiased studies are needed before virtual colonoscopy can be dismissedSteve Halligan
Department of Intestinal Imaging and Cancer Research UK Colorectal Cancer Unit, St Mark s Hospital, Northwick Park, Middlesex HA1 3UJ, UK
Lancet 365:275-6. 2005
- NCF1 (p47phox) and ncf1 pseudogenes are not associated with inflammatory bowel diseaseNirosha Suraweera
Cancer Research UK Colorectal Cancer Unit, Harrow, Middlesex, United Kingdom
Inflamm Bowel Dis 10:758-62. 2004..3%). Our data show there is no association of the 1:1 ratio with IBD and that susceptibility is unlikely to be a consequence of an inherited 1:1, rather than a 2:1 (PsiNCF1:NCF1) ratio...
- Understanding intentions and action in colorectal cancer screeningEmily Power
Health Behaviour Research Centre, Department of Epidemiology and Public Health, University College London, London, UK
Ann Behav Med 35:285-94. 2008..Factors involved in forming intentions to attend cancer screening may be different from those involved in translating intentions into action...