Roy D Mugerwa

Summary

Affiliation: Ministry of Health
Country: Uganda

Publications

  1. pmc Wasting among Uganda men with pulmonary tuberculosis is associated with linear regain in lean tissue mass during and after treatment in contrast to women with wasting who regain fat tissue mass: prospective cohort study
    Ezekiel Mupere
    Department of Paediatrics and Child Health College of Health Sciences, Makerere University Kampala, Kampala, Uganda
    BMC Infect Dis 14:24. 2014
  2. pmc First trial of the HIV-1 vaccine in Africa: Ugandan experience
    Roy D Mugerwa
    Department of Medicine, Makerere University Medical School, Kampala, Uganda
    BMJ 324:226-9. 2002
  3. pmc Low-cost rapid detection of rifampicin resistant tuberculosis using bacteriophage in Kampala, Uganda
    Hamidou Traore
    London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
    Ann Clin Microbiol Antimicrob 6:1. 2007
  4. pmc Comparison of rapid tests for detection of rifampicin-resistant Mycobacterium tuberculosis in Kampala, Uganda
    Sam Ogwang
    Department of Medical Microbiology, Makerere University College of Health Sciences, Kampala, Uganda
    BMC Infect Dis 9:139. 2009
  5. ncbi Incidence and predictors of mortality and the effect of tuberculosis immune reconstitution inflammatory syndrome in a cohort of TB/HIV patients commencing antiretroviral therapy
    William Worodria
    Department of Medicine, Makerere University College of Health Sciences, Mulago Hospital, Kampala, Uganda
    J Acquir Immune Defic Syndr 58:32-7. 2011
  6. pmc Treatment outcomes of new tuberculosis patients hospitalized in Kampala, Uganda: a prospective cohort study
    Bruce J Kirenga
    Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda
    PLoS ONE 9:e90614. 2014
  7. ncbi Immunoadjuvant prednisolone therapy for HIV-associated tuberculosis: a phase 2 clinical trial in Uganda
    Harriet Mayanja-Kizza
    Department of Medicine, Makerere University Medical School, Kampala, Uganda
    J Infect Dis 191:856-65. 2005
  8. pmc Men's circumcision status and women's risk of HIV acquisition in Zimbabwe and Uganda
    Abigail Norris Turner
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    AIDS 21:1779-89. 2007
  9. pmc Effect of tuberculosis preventive therapy on HIV disease progression and survival in HIV-infected adults
    Hyun J Lim
    Division of Biostatistics, Department of Population Health, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    HIV Clin Trials 7:172-83. 2006
  10. ncbi Delayed-type hypersensitivity skin test reactivity and survival in HIV-infected patients in Uganda: should anergy be a criterion to start antiretroviral therapy in low-income countries?
    Edward C Jones-Lopez
    Department of Medicine, UMDNJ New Jersey Medical School, Newark, New Jersey, USA
    Am J Trop Med Hyg 74:154-61. 2006

Collaborators

Detail Information

Publications17

  1. pmc Wasting among Uganda men with pulmonary tuberculosis is associated with linear regain in lean tissue mass during and after treatment in contrast to women with wasting who regain fat tissue mass: prospective cohort study
    Ezekiel Mupere
    Department of Paediatrics and Child Health College of Health Sciences, Makerere University Kampala, Kampala, Uganda
    BMC Infect Dis 14:24. 2014
    ..We therefore determined the effect of wasting on rate of mean change in lean tissue and fat mass as measured by bioelectrical impedance analysis (BIA), and mean change in body mass index (BMI) during and after tuberculosis treatment...
  2. pmc First trial of the HIV-1 vaccine in Africa: Ugandan experience
    Roy D Mugerwa
    Department of Medicine, Makerere University Medical School, Kampala, Uganda
    BMJ 324:226-9. 2002
  3. pmc Low-cost rapid detection of rifampicin resistant tuberculosis using bacteriophage in Kampala, Uganda
    Hamidou Traore
    London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
    Ann Clin Microbiol Antimicrob 6:1. 2007
    ..tuberculosis isolates for resistance to rifampicin. The purpose of this study was to investigate the performance of this technology in Kampala, Uganda...
  4. pmc Comparison of rapid tests for detection of rifampicin-resistant Mycobacterium tuberculosis in Kampala, Uganda
    Sam Ogwang
    Department of Medical Microbiology, Makerere University College of Health Sciences, Kampala, Uganda
    BMC Infect Dis 9:139. 2009
    ..The aim of the present study was to assess the feasibility of implementing technology for rapid detection of rifampicin resistance in a high disease burden setting in Africa...
  5. ncbi Incidence and predictors of mortality and the effect of tuberculosis immune reconstitution inflammatory syndrome in a cohort of TB/HIV patients commencing antiretroviral therapy
    William Worodria
    Department of Medicine, Makerere University College of Health Sciences, Mulago Hospital, Kampala, Uganda
    J Acquir Immune Defic Syndr 58:32-7. 2011
    ..Tuberculosis-HIV (TB-HIV) coinfection remains an important cause of mortality in antiretroviral therapy (ART) programs. In a cohort of TB-HIV-coinfected patients starting ART, we examined the incidence and predictors of early mortality...
  6. pmc Treatment outcomes of new tuberculosis patients hospitalized in Kampala, Uganda: a prospective cohort study
    Bruce J Kirenga
    Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda
    PLoS ONE 9:e90614. 2014
    ..We sought to investigate the reasons for hospitalisation and the predictors of poor treatment outcomes and mortality in a cohort of hospitalized new TB patients in Kampala, Uganda...
  7. ncbi Immunoadjuvant prednisolone therapy for HIV-associated tuberculosis: a phase 2 clinical trial in Uganda
    Harriet Mayanja-Kizza
    Department of Medicine, Makerere University Medical School, Kampala, Uganda
    J Infect Dis 191:856-65. 2005
    ..Conclusion. The benefits of prednisolone therapy on immune activation and CD4(+) T cell counts do not outweigh the risks of adverse events in HIV-infected patients with TB and preserved immune function...
  8. pmc Men's circumcision status and women's risk of HIV acquisition in Zimbabwe and Uganda
    Abigail Norris Turner
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    AIDS 21:1779-89. 2007
    ..To assess whether male circumcision of the primary sex partner is associated with women's risk of HIV...
  9. pmc Effect of tuberculosis preventive therapy on HIV disease progression and survival in HIV-infected adults
    Hyun J Lim
    Division of Biostatistics, Department of Population Health, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    HIV Clin Trials 7:172-83. 2006
    ..To determine whether tuberculosis (TB) preventive therapies alter the rate of disease progression to AIDS or death and to identify significant prognostic factors for HIV disease progression to AIDS...
  10. ncbi Delayed-type hypersensitivity skin test reactivity and survival in HIV-infected patients in Uganda: should anergy be a criterion to start antiretroviral therapy in low-income countries?
    Edward C Jones-Lopez
    Department of Medicine, UMDNJ New Jersey Medical School, Newark, New Jersey, USA
    Am J Trop Med Hyg 74:154-61. 2006
    ..Anergy is a strong and independent predictor of death. World Health Organization criteria to start ARV may be strengthened with the addition of DTH testing, an inexpensive and readily available tool in sub-Saharan Africa...
  11. pmc Vdelta2+ gammadelta T cell function in Mycobacterium tuberculosis- and HIV-1-positive patients in the United States and Uganda: application of a whole-blood assay
    Roxana E Rojas
    Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, OH 44106, USA
    J Infect Dis 192:1806-14. 2005
    ..Vdelta 2(+) T cells recognize phosphoantigens, such as bromohydrin pyrophosphate (BrHPP), and link innate and adaptive immunity...
  12. ncbi Linkage and association analysis of candidate genes for TB and TNFalpha cytokine expression: evidence for association with IFNGR1, IL-10, and TNF receptor 1 genes
    Catherine M Stein
    Department of Epidemiology and Biostatistics, Case Western Reserve University, Wolstein Research Building Room 1303, 2103 Cornell Rd, Cleveland, OH 44106, USA
    Hum Genet 121:663-73. 2007
    ..This study further illustrates the utility of such a model for disentangling complex traits...
  13. pmc Immune correlates of acute Mycobacterium tuberculosis infection in household contacts in Kampala, Uganda
    Christopher C Whalen
    Department of Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
    Am J Trop Med Hyg 75:55-61. 2006
    ....
  14. ncbi Early virological response of zidovudine/lamivudine/abacavir for patients co-infected with HIV and tuberculosis in Uganda
    Padmini Srikantiah
    HIV AIDS Division, San Francisco General Hospital, University of California, San Francisco, California, USA
    AIDS 21:1972-4. 2007
    ..No cases of hypersensitivity or immune reconstitution syndrome were observed. These data support the continuing evaluation of nucleoside-based antiretroviral regimens as an alternative treatment for this population...
  15. pmc Rate and amplification of drug resistance among previously-treated patients with tuberculosis in Kampala, Uganda
    Beth Temple
    Medical Research Council Uganda Virus Research Institute, Uganda Research Unit on AIDS, Entebbe, Uganda
    Clin Infect Dis 47:1126-34. 2008
    ..There is a need to measure the extent of and risk factors for drug resistance in such patients...
  16. pmc Burden of tuberculosis in Kampala, Uganda
    David Guwatudde
    Institute of Public Health, Makerere University, Kampala, Uganda
    Bull World Health Organ 81:799-805. 2003
    ..To determine the prevalence and incidence of tuberculosis in one of Uganda's poor peri-urban areas...
  17. ncbi Evidence for a major gene influence on tumor necrosis factor-alpha expression in tuberculosis: path and segregation analysis
    Catherine M Stein
    Department of Epidemiology and Biostatistics, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA
    Hum Hered 60:109-18. 2005
    ..Furthermore, these studies have not accounted for the influence of shared environment within households on TB risk, which may spuriously inflate estimates of heritability...